(22 nodes) Glycosylphosphatidylinositol (GPI)-anchor biosynthesis network (Aspergillus clavatus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Predicted Interactions

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Your Input:
	ACLA_003520	PIG-P domain-containing protein. (340 aa)
	ACLA_054460	GPI-anchor biosynthetic protein (Mcd4), putative. (1015 aa)
	ACLA_009320	Mannosyltransferase. (535 aa)
	ACLA_015600	N-acetylglucosaminyl-phosphatidylinositol deacetylase, putative. (304 aa)
	ACLA_007230	GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins. (1155 aa)
	ACLA_088980	GPI transamidase component PIG-S, putative. (593 aa)
	ACLA_094380	GPI-anchor biosynthesis protein (Pig-F), putative. (284 aa)
	ACLA_066260	GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly. Required for cell wall integrity. (416 aa)
	ACLA_047560	GPI transamidase component PIG-U, putative. (415 aa)
	ACLA_048500	Mannosyltransferase. (797 aa)
	ACLA_050370	GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. (441 aa)
	ACLA_035110	Phosphatidylinositol:UDP-GlcNAc transferase PIG-C. (514 aa)
	ACLA_037710	N-acetylglucosaminyl transferase component Gpi1. (718 aa)
	ACLA_041060	Uncharacterized protein. (224 aa)
	ACLA_095280	Sulfatase, putative. (862 aa)
	ACLA_096310	Phosphoethanolamine N-methyltransferase, putative. (1069 aa)
	ACLA_018560	Phosphatidylinositol:UDP-GlcNAc transferase subunit PIG-A. (489 aa)
	ACLA_020040	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (398 aa)
	ACLA_020490	GPI-anchored wall transfer protein; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. (501 aa)
	ACLA_031500	Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family. (79 aa)
	ACLA_083390	GPI transamidase component Gpi16, putative. (599 aa)
	ACLA_086010	GPI transamidase component (GAA1), putative. (684 aa)

Your Current Organism:

Aspergillus clavatus

NCBI taxonomy Id: 344612
Other names: A. clavatus NRRL 1, Aspergillus clavatus NRRL 1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACLA_003520	ACLA_009320	A1C5H1	A1C9U4	PIG-P domain-containing protein.	Mannosyltransferase.	0.555
ACLA_003520	ACLA_015600	A1C5H1	A1CBK0	PIG-P domain-containing protein.	N-acetylglucosaminyl-phosphatidylinositol deacetylase, putative.	0.938
ACLA_003520	ACLA_018560	A1C5H1	A1CND1	PIG-P domain-containing protein.	Phosphatidylinositol:UDP-GlcNAc transferase subunit PIG-A.	0.992
ACLA_003520	ACLA_020040	A1C5H1	A1CNS6	PIG-P domain-containing protein.	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	0.589
ACLA_003520	ACLA_031500	A1C5H1	A1CRZ6	PIG-P domain-containing protein.	Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family.	0.988
ACLA_003520	ACLA_035110	A1C5H1	A1CJI4	PIG-P domain-containing protein.	Phosphatidylinositol:UDP-GlcNAc transferase PIG-C.	0.989
ACLA_003520	ACLA_037710	A1C5H1	A1CK87	PIG-P domain-containing protein.	N-acetylglucosaminyl transferase component Gpi1.	0.988
ACLA_003520	ACLA_041060	A1C5H1	A1CL66	PIG-P domain-containing protein.	Uncharacterized protein.	0.989
ACLA_003520	ACLA_047560	A1C5H1	A1CHD2	PIG-P domain-containing protein.	GPI transamidase component PIG-U, putative.	0.448
ACLA_003520	ACLA_048500	A1C5H1	A1CHM5	PIG-P domain-containing protein.	Mannosyltransferase.	0.595
ACLA_003520	ACLA_050370	A1C5H1	A1CI60	PIG-P domain-containing protein.	GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis.	0.595
ACLA_003520	ACLA_054460	A1C5H1	A1C975	PIG-P domain-containing protein.	GPI-anchor biosynthetic protein (Mcd4), putative.	0.558
ACLA_003520	ACLA_066260	A1C5H1	A1CGB0	PIG-P domain-containing protein.	GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly. Required for cell wall integrity.	0.400
ACLA_003520	ACLA_083390	A1C5H1	A1CTK7	PIG-P domain-containing protein.	GPI transamidase component Gpi16, putative.	0.588
ACLA_003520	ACLA_086010	A1C5H1	A1CUB7	PIG-P domain-containing protein.	GPI transamidase component (GAA1), putative.	0.589
ACLA_003520	ACLA_095280	A1C5H1	A1CM08	PIG-P domain-containing protein.	Sulfatase, putative.	0.539
ACLA_003520	ACLA_096310	A1C5H1	A1CMB1	PIG-P domain-containing protein.	Phosphoethanolamine N-methyltransferase, putative.	0.605
ACLA_007230	ACLA_018560	A1CDN7	A1CND1	GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.	Phosphatidylinositol:UDP-GlcNAc transferase subunit PIG-A.	0.565
ACLA_007230	ACLA_020040	A1CDN7	A1CNS6	GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	0.959
ACLA_007230	ACLA_035110	A1CDN7	A1CJI4	GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.	Phosphatidylinositol:UDP-GlcNAc transferase PIG-C.	0.553