STRINGSTRING
ACLA_057210 ACLA_057210 ACLA_057260 ACLA_057260 ACLA_057320 ACLA_057320 ACLA_057960 ACLA_057960 ACLA_058130 ACLA_058130 ACLA_058360 ACLA_058360 ACLA_000670 ACLA_000670 ACLA_002100 ACLA_002100 ACLA_002730 ACLA_002730 fal1 fal1 ACLA_068260 ACLA_068260 ACLA_068370 ACLA_068370 ACLA_068380 ACLA_068380 dbp2 dbp2 LSM4 LSM4 ACLA_073860 ACLA_073860 ACLA_074190 ACLA_074190 ACLA_074440 ACLA_074440 ACLA_075860 ACLA_075860 ACLA_054030 ACLA_054030 ACLA_054040 ACLA_054040 ACLA_054770 ACLA_054770 ACLA_010440 ACLA_010440 ACLA_011490 ACLA_011490 ACLA_011830 ACLA_011830 ACLA_012210 ACLA_012210 ACLA_013700 ACLA_013700 ACLA_014040 ACLA_014040 ACLA_014690 ACLA_014690 ACLA_014940 ACLA_014940 ACLA_015620 ACLA_015620 ACLA_015740 ACLA_015740 ACLA_016460 ACLA_016460 ACLA_016490 ACLA_016490 ACLA_016900 ACLA_016900 ACLA_061920 ACLA_061920 LSM5 LSM5 ACLA_007010 ACLA_007010 ACLA_007670 ACLA_007670 lsm6 lsm6 ACLA_088270 ACLA_088270 ACLA_089160 ACLA_089160 ACLA_089530 ACLA_089530 ACLA_091280 ACLA_091280 ACLA_091810 ACLA_091810 ACLA_065250 ACLA_065250 ACLA_065640 ACLA_065640 ACLA_046120 ACLA_046120 ACLA_046830 ACLA_046830 ACLA_047110 ACLA_047110 prp28 prp28 ACLA_049040 ACLA_049040 ACLA_049460 ACLA_049460 ACLA_049620 ACLA_049620 ACLA_050920 ACLA_050920 ACLA_051190 ACLA_051190 ACLA_052350 ACLA_052350 ACLA_034390 ACLA_034390 ACLA_034740 ACLA_034740 ACLA_038350 ACLA_038350 ACLA_040160 ACLA_040160 ACLA_095350 ACLA_095350 ACLA_095410 ACLA_095410 ACLA_096500 ACLA_096500 sub2 sub2 ACLA_098330 ACLA_098330 ACLA_018520 ACLA_018520 ACLA_021120 ACLA_021120 ACLA_021410 ACLA_021410 ACLA_021570 ACLA_021570 LSM8 LSM8 ACLA_024550 ACLA_024550 ACLA_024810 ACLA_024810 ACLA_025230 ACLA_025230 ACLA_025340 ACLA_025340 ACLA_025350 ACLA_025350 prp5 prp5 ACLA_026120 ACLA_026120 ACLA_027170 ACLA_027170 ACLA_028120 ACLA_028120 ACLA_028900 ACLA_028900 ACLA_030750 ACLA_030750 ACLA_079710 ACLA_079710 ACLA_080400 ACLA_080400 ACLA_080710 ACLA_080710 ACLA_081440 ACLA_081440 ACLA_082970 ACLA_082970 ACLA_086710 ACLA_086710
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACLA_057210Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (150 aa)
ACLA_057260Hsp70 chaperone (HscA), putative; Belongs to the heat shock protein 70 family. (614 aa)
ACLA_057320U5 snRNP component (116 kDa), putative. (986 aa)
ACLA_057960Pre-mRNA splicing factor, putative. (538 aa)
ACLA_058130Pre-mRNA splicing helicase, putative. (2209 aa)
ACLA_058360Small nuclear ribonucleoprotein G. (78 aa)
ACLA_000670Splicing factor 3b, subunit 2, 145kD. (548 aa)
ACLA_002100Transcriptional regulator Cwf13/SkiP, putative. (578 aa)
ACLA_002730Splicing factor 3a subunit 3, putative. (504 aa)
fal1ATP-dependent RNA helicase fal1; ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA (By similarity). Belongs to the DEAD box helicase family. DDX48/FAL1 subfamily. (399 aa)
ACLA_068260mRNA splicing factor (Prp1/Zer1), putative. (939 aa)
ACLA_068370Pre-mRNA branch site protein p14, putative. (113 aa)
ACLA_068380Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (126 aa)
dbp2ATP-dependent RNA helicase dbp2; ATP-dependent RNA helicase involved nonsense-mediated mRNA decay and ribosome biogenesis through rRNA processing. (549 aa)
LSM4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (119 aa)
ACLA_073860Splicing factor 3B subunit 1, putative. (1246 aa)
ACLA_074190U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (98 aa)
ACLA_074440LSM domain protein. (88 aa)
ACLA_075860Pre-mRNA splicing factor ini1, putative. (108 aa)
ACLA_054030Pre-mRNA-splicing factor; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome. (1421 aa)
ACLA_054040Nuclear matrix protein. (669 aa)
ACLA_054770Pre-RNA splicing factor Slt11, putative. (383 aa)
ACLA_010440Nucleoside-diphosphate-sugar epimerase, putative. (2450 aa)
ACLA_011490RNA binding protein, putative. (247 aa)
ACLA_011830Pre-mRNA splicing factor, putative. (242 aa)
ACLA_012210RNA binding protein, putative. (332 aa)
ACLA_013700RNA helicase-like splicing factor (HRH1), putative. (1231 aa)
ACLA_014040Small nuclear ribonucleoprotein U2, A. (266 aa)
ACLA_014690Pre-mRNA splicing factor RNA helicase (Prp43), putative. (772 aa)
ACLA_014940DNA repair and transcription protein (Xab2), putative. (854 aa)
ACLA_015620U6 small nuclear ribonucleoprotein (Lsm3), putative. (74 aa)
ACLA_015740Small nuclear ribonucleoprotein Sm D2. (115 aa)
ACLA_016460U1 small nuclear ribonucleoprotein 70 kDa. (377 aa)
ACLA_016490Cell cycle control protein (Cwf8), putative. (526 aa)
ACLA_016900RNA binding domain protein. (264 aa)
ACLA_061920U2 auxiliary factor small subunit, putative. (209 aa)
LSM5U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (83 aa)
ACLA_007010U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (583 aa)
ACLA_007670Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (95 aa)
lsm6U6 snRNA-associated Sm-like protein LSm6; Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway. Component of the nuclear LSM2- LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 [...] (78 aa)
ACLA_088270RNA binding domain protein. (194 aa)
ACLA_089160Cell division control protein (Cdc5), putative. (792 aa)
ACLA_089530Small nuclear ribonucleoprotein Sm D1; Involved in pre-mRNA splicing. Binds snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site; Belongs to the snRNP core protein family. (123 aa)
ACLA_091280RNA binding protein (Rbm8A), putative. (159 aa)
ACLA_091810Pre-mRNA splicing factor (Prp8), putative. (2354 aa)
ACLA_065250U5 snRNP complex subunit, putative. (359 aa)
ACLA_065640DUF1716 domain protein. (585 aa)
ACLA_046120G-patch DNA repair protein (Drt111), putative. (516 aa)
ACLA_046830SnRNP assembly factor, putative. (614 aa)
ACLA_047110Small nuclear ribonucleoprotein SmB, putative. (219 aa)
prp28Pre-mRNA-splicing ATP-dependent RNA helicase prp28; ATP-dependent RNA helicase involved in mRNA splicing. May destabilize the U1/5'-splice site duplex to permit an effective competition for the 5'-splice site by the U6 snRNA, resulting in the switch between U1 and U6 at the 5'-splice site. May also act to unwind the U4/U6 base-pairing interaction in the U4/U6/U5 snRNP, facilitating the first covalent step of splicing (By similarity). (798 aa)
ACLA_049040SYF2 splicing factor domain protein. (416 aa)
ACLA_049460Small nuclear ribonucleoprotein Sm D3. (136 aa)
ACLA_049620DNA binding protein SART-1, putative. (668 aa)
ACLA_050920Splicing factor 3a subunit 2, putative. (272 aa)
ACLA_051190WD repeat-containing protein. (375 aa)
ACLA_052350U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. (218 aa)
ACLA_034390Pre-mRNA splicing factor, putative. (528 aa)
ACLA_034740mRNA splicing protein, putative. (484 aa)
ACLA_038350CID domain-containing protein. (818 aa)
ACLA_040160Spliceosomal protein DIB1; Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis; Belongs to the DIM1 family. (152 aa)
ACLA_095350Splicing factor 3b subunit 4. (354 aa)
ACLA_095410Cap binding protein. (848 aa)
ACLA_096500SNRNP27 domain-containing protein. (238 aa)
sub2ATP-dependent RNA helicase sub2; ATP-binding RNA helicase involved in transcription elongation and required for the export of mRNA out of the nucleus. SUB2 plays also a role in pre-mRNA splicing and spliceosome assembly. May be involved in rDNA and telomeric silencing, and maintenance of genome integrity (By similarity); Belongs to the DEAD box helicase family. DECD subfamily. (441 aa)
ACLA_098330Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (161 aa)
ACLA_018520mRNA splicing factor (Prp18), putative. (370 aa)
ACLA_021120Small nuclear ribonucleoprotein (LSM7), putative. (140 aa)
ACLA_021410C2H2 finger domain protein, putative. (218 aa)
ACLA_021570U4/U6 small nuclear ribonucleoprotein, putative. (586 aa)
LSM8U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (98 aa)
ACLA_024550Mago nashi domain protein. (110 aa)
ACLA_024810mRNA splicing protein (Prp5), putative. (452 aa)
ACLA_025230Formin binding protein (FNB3), putative. (805 aa)
ACLA_025340Cell cycle control protein (Cwf4), putative. (676 aa)
ACLA_025350Pre-mRNA splicing factor (Prp31), putative. (518 aa)
prp5Pre-mRNA-processing ATP-dependent RNA helicase prp5; ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity); Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily. (1192 aa)
ACLA_026120Uncharacterized protein. (202 aa)
ACLA_027170Molecular chaperone Hsp70; Belongs to the heat shock protein 70 family. (638 aa)
ACLA_028120Uncharacterized protein. (216 aa)
ACLA_028900Splicing factor subunit; Belongs to the SF3B5 family. (84 aa)
ACLA_030750mRNA splicing factor RNA helicase (Prp16), putative. (911 aa)
ACLA_079710mRNA splicing factor RNA helicase (Cdc28), putative. (1129 aa)
ACLA_080400Nuclear cap-binding protein subunit 2. (138 aa)
ACLA_080710Cwf15/Cwc15 cell cycle control family protein. (239 aa)
ACLA_081440mRNA splicing factor (Prp17), putative. (582 aa)
ACLA_082970Tudor domain-containing protein. (312 aa)
ACLA_086710Nuclear mRNA splicing factor, putative. (1209 aa)
Your Current Organism:
Aspergillus clavatus
NCBI taxonomy Id: 344612
Other names: A. clavatus NRRL 1, Aspergillus clavatus NRRL 1
Server load: low (26%) [HD]