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A0A090LKQ0 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (664 aa) | ||||
A0A090LKN8 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (152 aa) | ||||
A0A090LKM7 | CDK-activating kinase assembly factor MAT1. (309 aa) | ||||
A0A090LKF1 | Replication factor C subunit 1. (1382 aa) | ||||
A0A090LKD6 | Nucleolar complex protein 3 homolog. (777 aa) | ||||
A0A090L9I6 | RMI1_N domain-containing protein. (593 aa) | ||||
A0A090LK28 | Exosome complex component RRP46. (223 aa) | ||||
A0A090LJZ0 | DNA repair protein Rad51 homolog; Belongs to the RecA family. (333 aa) | ||||
NTH1 | Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. (286 aa) | ||||
A0A090LJJ3 | DNA polymerase. (1425 aa) | ||||
A0A090LJH5 | DNA repair protein REV1. (733 aa) | ||||
A0A090LJ42 | Uncharacterized protein. (338 aa) | ||||
A0A090LIS9 | X-ray repair cross-complementing protein 6. (491 aa) | ||||
A0A090LIP5 | Endonuclease. (266 aa) | ||||
A0A090MXG1 | Zinc finger, RING-type domain and Zinc finger, RING/FYVE/PHD-type domain-containing protein. (196 aa) | ||||
A0A090MUJ9 | RuvB-like helicase; Belongs to the RuvB family. (448 aa) | ||||
A0A090L9A7 | Double-strand break repair protein MRE11A; Belongs to the MRE11/RAD32 family. (541 aa) | ||||
A0A090L977 | Uncharacterized protein. (287 aa) | ||||
A0A090L952 | Alpha-1,3-glucosyltransferase; Belongs to the ALG6/ALG8 glucosyltransferase family. (766 aa) | ||||
A0A090L8Z5 | Zinc finger, RING-type domain and Zinc finger, RING/FYVE/PHD-type domain-containing protein. (397 aa) | ||||
A0A090L8Y8 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (542 aa) | ||||
A0A090L8X4 | ORC4_C domain-containing protein. (402 aa) | ||||
A0A090L8S5 | Ubiquitin-conjugating enzyme E2-17 kDa; Belongs to the ubiquitin-conjugating enzyme family. (220 aa) | ||||
A0A090L8P1 | BTB/POZ-like domain and BTB/POZ fold domain and BTB/POZ domain-containing protein. (252 aa) | ||||
A0A090L8M9 | annotation not available (462 aa) | ||||
A0A090L8M4 | Uncharacterized protein. (427 aa) | ||||
A0A090L8K2 | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2154 aa) | ||||
A0A090L8E2 | SAP domain and Zinc finger, MIZ-type domain-containing protein. (640 aa) | ||||
A0A090L8D6 | EKC/KEOPS complex subunit TPRKB; Belongs to the CGI121/TPRKB family. (250 aa) | ||||
A0A090L7P2 | Transcription factor CBF/NF-Y/archaeal histone domain and Histone-fold domain-containing protein. (493 aa) | ||||
A0A090L7L1 | Mutagen-sensitive 301. (854 aa) | ||||
A0A090L7G6 | annotation not available (465 aa) | ||||
A0A090L7F3 | annotation not available (646 aa) | ||||
A0A090L7F1 | Tetratricopeptide repeat protein 5. (415 aa) | ||||
A0A090L784 | Serine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family. (2555 aa) | ||||
A0A090L753 | XPG-I domain and 5'-3' exonuclease, C-terminal domain-containing protein. (501 aa) | ||||
A0A090L6K6 | Cell division control protein 45 homolog. (563 aa) | ||||
A0A090L6G6 | DNA repair protein complementing XP-A cells. (128 aa) | ||||
A0A090L5Z5 | Poly [ADP-ribose] polymerase 1. (456 aa) | ||||
A0A090L5Y0 | Ribonuclease H1. (177 aa) | ||||
A0A090L5W9 | DNA polymerase eta. (585 aa) | ||||
A0A090L5I4 | DNA excision repair protein ERCC-1. (207 aa) | ||||
A0A090L5F7 | SprT-like domain-containing protein. (465 aa) | ||||
A0A090L5C9 | DNA ligase 4. (740 aa) | ||||
A0A090L5A0 | Replication factor C subunit 2. (329 aa) | ||||
A0A090L542 | LD34181p. (1004 aa) | ||||
A0A090L4Z7 | Uncharacterized protein. (408 aa) | ||||
A0A090L4Z4 | Uncharacterized protein. (1143 aa) | ||||
A0A090L4V1 | ApaG domain and Hemimethylated DNA-binding domain-containing protein. (349 aa) | ||||
A0A090L4I3 | Zinc finger, MIZ-type domain-containing protein. (368 aa) | ||||
A0A090L4C9 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (417 aa) | ||||
A0A090L490 | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (311 aa) | ||||
A0A090L456 | Protein MCM10 homolog. (672 aa) | ||||
A0A090L3W0 | Origin recognition complex, subunit 2 family-containing protein. (312 aa) | ||||
A0A090L3T2 | PRP19/PSO4 homolog. (488 aa) | ||||
A0A090L3L0 | Zinc finger, RING/FYVE/PHD-type domain-containing protein. (399 aa) | ||||
A0A090L3I2 | annotation not available (408 aa) | ||||
A0A090L3C6 | DNA excision repair protein ERCC-6. (291 aa) | ||||
A0A090L2V3 | Homeotic protein ocelliless. (325 aa) | ||||
A0A090L2R7 | Twinkle protein, mitochondrial. (661 aa) | ||||
A0A090L2P2 | Uncharacterized protein. (859 aa) | ||||
A0A090L2M0 | Zinc finger, RING/FYVE/PHD-type domain-containing protein. (395 aa) | ||||
A0A090L2I2 | Uncharacterized protein. (343 aa) | ||||
A0A090L263 | Uncharacterized protein. (380 aa) | ||||
A0A090L259 | Serine/threonine-protein phosphatase. (322 aa) | ||||
A0A090L207 | Zinc finger, RING-type domain and Zinc finger, RING/FYVE/PHD-type domain-containing protein. (526 aa) | ||||
A0A090L1Z9 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1. (487 aa) | ||||
A0A090L1U9 | Endonuclease. (162 aa) | ||||
A0A090L1Q6 | Protein RTF2 homolog. (224 aa) | ||||
A0A090L1N6 | annotation not available (215 aa) | ||||
A0A090L1J7 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (806 aa) | ||||
A0A090L1F7 | Zinc finger, MIZ-type domain-containing protein. (854 aa) | ||||
A0A090L1C6 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (587 aa) | ||||
A0A090L1A0 | Mismatch repair endonuclease PMS2. (718 aa) | ||||
A0A090L171 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (269 aa) | ||||
A0A090L0Z0 | Replication factor C subunit 4. (362 aa) | ||||
A0A090L0T6 | UNC93-like protein MFSD11. (453 aa) | ||||
A0A090L0Q1 | Zinc finger protein ZPR1. (436 aa) | ||||
A0A090KZU7 | Integrator complex subunit 3. (1112 aa) | ||||
A0A090KYR3 | Bloom syndrome protein. (735 aa) | ||||
A0A090KYQ8 | Zinc finger, MIZ-type domain-containing protein. (399 aa) | ||||
A0A090KXX7 | DNA repair endonuclease XPF. (866 aa) | ||||
A0A090KXF1 | Twinkle protein, mitochondrial. (738 aa) | ||||
A0A090KXE1 | Helicase ATP-binding domain-containing protein. (985 aa) | ||||
A0A090KXC5 | Uncharacterized protein. (1161 aa) | ||||
A0A090KX93 | General transcription factor IIH subunit 5. (72 aa) | ||||
A0A090KX43 | MMS19 nucleotide excision repair protein homolog. (934 aa) | ||||
A0A090KWZ2 | Zinc finger, RING-type domain and Zinc finger, RING/FYVE/PHD-type domain-containing protein. (427 aa) | ||||
A0A090KWK3 | Homeotic protein ocelliless. (424 aa) | ||||
A0A090KWH2 | Proteasome activator complex subunit 4B. (1892 aa) | ||||
A0A090KW75 | Protein-tyrosine phosphatase, receptor/non-receptor type domain-containing protein. (74 aa) | ||||
A0A090L9L2 | Zinc finger, RING-type domain and Zinc finger, RING/FYVE/PHD-type domain-containing protein. (353 aa) | ||||
A0A090L9R8 | Uncharacterized protein. (161 aa) | ||||
A0A090L9U3 | DNA helicase; Belongs to the MCM family. (811 aa) | ||||
A0A090L9X2 | Bloom syndrome protein. (1034 aa) | ||||
A0A090L9Z2 | Tonsoku-like protein. (1159 aa) | ||||
A0A090L9Z5 | Transformation/transcription domain-associated protein. (3960 aa) | ||||
A0A090LA04 | Bloom syndrome protein. (1520 aa) | ||||
A0A090LA41 | Endoribonuclease Dicer; Belongs to the helicase family. Dicer subfamily. (1819 aa) | ||||
A0A090LA71 | DNA-directed primase/polymerase protein. (638 aa) | ||||
A0A090LA78 | Sld5 domain-containing protein. (131 aa) | ||||
A0A090LA91 | DNA topoisomerase 2-binding protein 1. (891 aa) | ||||
A0A090LAV4 | Fanconi anemia group J protein. (521 aa) | ||||
A0A090LAV9 | Armadillo-type fold domain-containing protein. (1522 aa) | ||||
A0A090LB58 | DNA excision repair protein haywire. (779 aa) | ||||
A0A090LB94 | Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family. (294 aa) | ||||
A0A090LBB6 | General transcription factor IIH subunit 1. (379 aa) | ||||
A0A090LBE3 | annotation not available (748 aa) | ||||
A0A090LBI1 | Uncharacterized protein. (472 aa) | ||||
A0A090LBI9 | annotation not available (1166 aa) | ||||
A0A090LBW5 | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4. (292 aa) | ||||
A0A090LBX2 | annotation not available (462 aa) | ||||
A0A090LBX7 | Mlh1. (805 aa) | ||||
A0A090LBZ6 | INO80 complex subunit D. (1293 aa) | ||||
A0A090LC06 | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1107 aa) | ||||
A0A090LC64 | N-glycosylase/DNA lyase. (305 aa) | ||||
A0A090LCH7 | Xeroderma pigmentosum D. (779 aa) | ||||
A0A090LCN1 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (781 aa) | ||||
A0A090LCP1 | DNA helicase; Belongs to the MCM family. (795 aa) | ||||
A0A090LCX5 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (392 aa) | ||||
A0A090LD11 | FANCI_HD2 domain-containing protein. (1294 aa) | ||||
A0A090LD92 | DNA damage-binding protein 1. (1141 aa) | ||||
MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (732 aa) | ||||
A0A090LDB0 | Transposase, ISXO2-like domain-containing protein. (293 aa) | ||||
A0A090LDF6 | Replication factor C subunit 5. (340 aa) | ||||
A0A090LDJ2 | DNA repair protein RAD50. (1309 aa) | ||||
A0A090MXG5 | DNA polymerase alpha subunit B. (494 aa) | ||||
A0A090MXH3 | DNA primase large subunit. (479 aa) | ||||
A0A090MXI5 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5. (894 aa) | ||||
A0A090MXK7 | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1414 aa) | ||||
A0A090MXL7 | Ring finger protein 113A. (153 aa) | ||||
A0A090MXQ4 | Histone-lysine N-methyltransferase, H3 lysine-79 specific. (1007 aa) | ||||
A0A090MY01 | Crossover junction endonuclease MUS81. (462 aa) | ||||
A0A090MY28 | E3 ubiquitin-protein ligase TRAIP. (363 aa) | ||||
A0A090MY83 | DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (329 aa) | ||||
A0A090MY85 | DNA polymerase epsilon subunit 2. (478 aa) | ||||
A0A090MYF0 | Cyclin-like domain-containing protein. (327 aa) | ||||
A0A090MYJ3 | DNA ligase 4. (740 aa) | ||||
A0A090MYN5 | Replication factor C subunit 3. (358 aa) | ||||
A0A090MYQ9 | FACT complex subunit SPT16. (1034 aa) | ||||
A0A090MYR9 | RMI1_N domain-containing protein. (847 aa) | ||||
A0A090MYW4 | Exonuclease 1. (530 aa) | ||||
A0A090MYX3 | Replication protein A 70 kDa DNA-binding subunit. (609 aa) | ||||
A0A090MZK1 | Ribonuclease H1. (182 aa) | ||||
A0A090MZK2 | DNA excision repair protein ERCC-6. (411 aa) | ||||
A0A090MZK7 | Bifunctional polynucleotide phosphatase/kinase. (416 aa) | ||||
A0A090MZR7 | Nuclear factor I. (491 aa) | ||||
A0A090N044 | SprT-like domain-containing protein. (382 aa) | ||||
A0A090N047 | Snurportin-1. (339 aa) | ||||
A0A090N048 | Transcription factor CBF/NF-Y/archaeal histone domain and Histone-fold domain-containing protein. (138 aa) | ||||
A0A090N049 | SAP domain-containing protein. (338 aa) | ||||
A0A090MUP8 | Zinc finger, RING/FYVE/PHD-type domain-containing protein. (365 aa) | ||||
A0A090MUR1 | Poly [ADP-ribose] polymerase 2. (538 aa) | ||||
A0A090MV00 | RuvB-like helicase; Belongs to the RuvB family. (655 aa) | ||||
A0A090MV02 | Zinc finger, C2H2 domain and Zinc finger, C2H2-like domain-containing protein. (526 aa) | ||||
A0A090MV84 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (771 aa) | ||||
A0A090MVC4 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (600 aa) | ||||
A0A090MVI5 | Thymidine kinase. (227 aa) | ||||
A0A090MVL4 | Putative deoxyribonuclease TATDN1. (317 aa) | ||||
A0A090MVU8 | UNC93-like protein MFSD11. (438 aa) | ||||
A0A090MVY7 | Transcription termination factor 2. (949 aa) | ||||
A0A090MVY9 | DNA polymerase delta subunit 2. (435 aa) | ||||
A0A090MVZ8 | BRCA2 and CDKN1A-interacting protein. (274 aa) | ||||
A0A090MW20 | Ribonuclease H1. (169 aa) | ||||
A0A090MW35 | Proteasome activator complex subunit 4B. (1933 aa) | ||||
A0A090MW92 | Transcriptional regulator ATRX. (993 aa) | ||||
A0A090MWH8 | Fanconi anemia group J protein. (757 aa) | ||||
A0A090MWJ5 | DNA replication complex GINS protein PSF2. (303 aa) | ||||
A0A090MWV8 | annotation not available (263 aa) | ||||
A0A090MX02 | Uncharacterized protein. (212 aa) | ||||
A0A090MX07 | SOSS complex subunit B homolog. (137 aa) | ||||
A0A090MX40 | P-loop containing Nucleoside triphosphate hydrolase domain-containing protein. (556 aa) | ||||
A0A090MX53 | DNA polymerase. (1286 aa) | ||||
A0A090MX80 | Timeless protein domain-containing protein. (850 aa) | ||||
A0A090MX87 | Putative apoptosis-inducing factor 1, mitochondrial. (633 aa) | ||||
A0A090MX94 | Zinc finger, RING-type domain and Zinc finger, RING/FYVE/PHD-type domain-containing protein. (491 aa) | ||||
A0A090MXD2 | Fanconi anemia group J protein. (320 aa) | ||||
A0A090MUA9 | DNA_MISMATCH_REPAIR_2 domain-containing protein. (859 aa) | ||||
A0A090MU66 | WD40-repeat-containing domain-containing protein. (429 aa) | ||||
A0A090MU36 | E3 ubiquitin-protein ligase TRIP12. (1951 aa) | ||||
A0A090LV35 | Wings apart-like protein homolog. (571 aa) | ||||
A0A090LTH3 | Uncharacterized protein. (508 aa) | ||||
A0A090LSM1 | Transposase, ISXO2-like domain-containing protein. (157 aa) | ||||
A0A090LRY7 | Transposase, ISXO2-like domain-containing protein. (275 aa) | ||||
A0A090LR85 | G1/S-specific cyclin-E; Belongs to the cyclin family. (495 aa) | ||||
A0A090LR29 | Ribonucleoside-diphosphate reductase subunit M2. (360 aa) | ||||
A0A090LQL9 | ATP-dependent DNA helicase Q1. (564 aa) | ||||
A0A090LQJ1 | DNA-directed primase/polymerase protein. (699 aa) | ||||
A0A090LQF1 | CDT1 Geminin-binding domain-like-containing protein. (729 aa) | ||||
A0A090LQ87 | Histone H4 transcription factor. (442 aa) | ||||
A0A090LP77 | annotation not available (479 aa) | ||||
A0A090LP26 | DNA helicase; Belongs to the MCM family. (763 aa) | ||||
A0A090LN96 | Mutagen-sensitive 301. (797 aa) | ||||
A0A090LMV8 | RNA exonuclease 4. (238 aa) | ||||
A0A090LMM2 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (843 aa) | ||||
A0A090LMF4 | DNA/RNA-binding protein KIN17. (373 aa) | ||||
A0A090LM61 | C6 domain-containing protein. (163 aa) | ||||
A0A090LLX1 | Nipped-B protein. (2177 aa) | ||||
A0A090LLU7 | DNA polymerase. (1066 aa) | ||||
A0A090LLT1 | Transposase, ISXO2-like domain-containing protein. (292 aa) | ||||
A0A090LLF0 | Zinc finger, RING-type domain and Zinc finger, RING/FYVE/PHD-type domain-containing protein. (608 aa) | ||||
A0A090LLA6 | Poly [ADP-ribose] polymerase. (729 aa) | ||||
A0A090LL93 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (468 aa) | ||||
A0A090LL80 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (784 aa) | ||||
A0A090LL63 | DNA-directed primase/polymerase protein. (724 aa) | ||||
A0A090LL18 | DNA repair protein RAD50. (1254 aa) | ||||
A0A090LKY3 | Tyrosyl-DNA phosphodiesterase 2. (340 aa) | ||||
A0A090LKU9 | Fanconi anemia group J protein. (1002 aa) | ||||
A0A090LIP2 | Tyrosyl-DNA phosphodiesterase 1. (445 aa) | ||||
A0A090LIN3 | Exosome component 10. (746 aa) | ||||
A0A090LIG2 | DNA ligase. (621 aa) | ||||
A0A090LI74 | UNC93-like protein MFSD11. (459 aa) | ||||
A0A090LI71 | DNA helicase; Belongs to the MCM family. (809 aa) | ||||
A0A090LI61 | MIP16420p. (141 aa) | ||||
A0A090LI43 | Ribonuclease H domain and Ribonuclease H-like domain-containing protein. (329 aa) | ||||
A0A090LHV2 | UDP-N-acetylglucosamine transporter. (339 aa) | ||||
A0A090LHS8 | Uncharacterized protein. (647 aa) | ||||
A0A090LHS0 | Uncharacterized protein. (570 aa) | ||||
A0A090LHN6 | Histone-lysine N-methyltransferase, H3 lysine-79 specific. (382 aa) | ||||
A0A090LHM4 | DNA repair protein complementing XP-C cells. (559 aa) | ||||
A0A090LH86 | Zinc finger, RING-type domain and Zinc finger, RING/FYVE/PHD-type domain-containing protein. (426 aa) | ||||
A0A090LH58 | Structural maintenance of chromosomes protein. (1204 aa) | ||||
A0A090LH54 | Methyltransferase-like protein 4; Belongs to the MT-A70-like family. (370 aa) | ||||
A0A090LH03 | DNA excision repair protein ERCC-6. (1042 aa) | ||||
A0A090LGY3 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (702 aa) | ||||
A0A090LGS3 | Probable ATP-dependent RNA helicase DDX11. (823 aa) | ||||
A0A090LGQ8 | DNA repair protein Sae2/CtIP family-containing protein. (320 aa) | ||||
A0A090LGN2 | Zinc finger, RING-type domain and Zinc finger, RING/FYVE/PHD-type domain-containing protein. (659 aa) | ||||
A0A090LGL8 | Transcription termination factor 2. (930 aa) | ||||
A0A090LGJ6 | Nipped-B protein. (1394 aa) | ||||
A0A090LGB9 | annotation not available (433 aa) | ||||
A0A090LG25 | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1406 aa) | ||||
A0A090LG13 | annotation not available (437 aa) | ||||
A0A090LG02 | FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (414 aa) | ||||
A0A090LFU6 | 5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. Plays a role in maintenance of steady-state concentration and turnover of microRNAs (miRNA) by degradation of mature miRNA. Degradation role is enhanced when in complex with paxt-1. Partially redundant to xrn-1 in miRNA guide strand degradation. Implicated in differential regulation of mRNAs such as let-7 by controlling the accumulation of mature miRNA. Positively regulates molting of the pharyngeal cuticle. (858 aa) | ||||
A0A090LFU1 | 5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. Plays a role in maintenance of steady-state concentration and turnover of microRNAs (miRNA) by degradation of mature miRNA. Degradation role is enhanced when in complex with paxt-1. Partially redundant to xrn-1 in miRNA guide strand degradation. Implicated in differential regulation of mRNAs such as let-7 by controlling the accumulation of mature miRNA. Positively regulates molting of the pharyngeal cuticle. (944 aa) | ||||
A0A090LFT2 | Enhancer of polycomb-like protein. (516 aa) | ||||
A0A090LFJ6 | MutS protein homolog 4. (840 aa) | ||||
A0A090LFJ2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1170 aa) | ||||
A0A090LFJ0 | WD repeat and HMG-box DNA-binding protein 1. (925 aa) | ||||
A0A090LFF7 | Origin recognition complex subunit 5. (429 aa) | ||||
A0A090LFA8 | DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily. (382 aa) | ||||
A0A090LF85 | DNA repair and recombination protein RAD54-like. (771 aa) | ||||
A0A090LF81 | N-alpha-acetyltransferase 25, NatB auxiliary subunit. (822 aa) | ||||
A0A090LF20 | Pachytene checkpoint protein 2 homolog. (403 aa) | ||||
A0A090LF05 | Belongs to the ubiquitin-conjugating enzyme family. (146 aa) | ||||
A0A090LEY8 | DNA polymerase subunit gamma-1. (1031 aa) | ||||
A0A090LEU0 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (609 aa) | ||||
A0A090LES0 | General transcription factor IIH subunit 3. (335 aa) | ||||
A0A090LEJ1 | DNA helicase; Belongs to the MCM family. (736 aa) | ||||
A0A090LEI3 | RMI1_N domain-containing protein. (491 aa) | ||||
A0A090LEC7 | General transcription factor IIH subunit. (457 aa) | ||||
A0A090LE74 | Uncharacterized protein. (1499 aa) | ||||
A0A090LE72 | Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (290 aa) | ||||
A0A090LE64 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (822 aa) | ||||
A0A090LE48 | MIF4-like, type 1/2/3 domain and Armadillo-type fold domain-containing protein. (280 aa) | ||||
FEN1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (366 aa) | ||||
A0A090LE13 | annotation not available (176 aa) | ||||
A0A090LDZ8 | Ubiquitin-conjugating enzyme E2-17 kDa; Belongs to the ubiquitin-conjugating enzyme family. (158 aa) | ||||
A0A090LDS3 | DNA replication ATP-dependent helicase/nuclease DNA2. (1032 aa) | ||||
A0A090LDQ1 | BTB/POZ-like domain and BTB/POZ fold domain and BTB/POZ domain-containing protein. (308 aa) | ||||
A0A090LDP0 | Cell division control protein 6 homolog. (377 aa) | ||||
A0A090LDK4 | General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (501 aa) |