STRINGSTRING
dapE dapE dapD dapD SEL78247.1 SEL78247.1 metXS metXS asd asd SEL67348.1 SEL67348.1 SEL52969.1 SEL52969.1 thrB thrB SEL96078.1 SEL96078.1 SEL59025.1 SEL59025.1 dapB dapB dapA dapA SEL47476.1 SEL47476.1 SEL96105.1 SEL96105.1 SEL22428.1 SEL22428.1 folD folD SEL27729.1 SEL27729.1 lysA lysA dapF dapF SEL47388.1 SEL47388.1 ilvE ilvE SEM13287.1 SEM13287.1 SEM13310.1 SEM13310.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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dapESuccinyldiaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (377 aa)
dapD2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. (273 aa)
SEL78247.1Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1228 aa)
metXSHomoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. (386 aa)
asdAspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (372 aa)
SEL67348.1Protein of unknown function. (83 aa)
SEL52969.15-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. (63 aa)
thrBHomoserine kinase type II; Belongs to the pseudomonas-type ThrB family. (316 aa)
SEL96078.1Homoserine dehydrogenase. (434 aa)
SEL59025.1Adenosylhomocysteine nucleosidase. (188 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (273 aa)
dapA4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (299 aa)
SEL47476.1Methionine synthase (B12-independent). (347 aa)
SEL96105.1L-threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (379 aa)
SEL22428.15,10-methylenetetrahydrofolate reductase (NAD(P)); Belongs to the methylenetetrahydrofolate reductase family. (278 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (282 aa)
SEL27729.1Aspartate kinase; Belongs to the aspartokinase family. (426 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (414 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (280 aa)
SEL47388.1Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (305 aa)
ilvEBranched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (308 aa)
SEM13287.1Protein of unknown function. (83 aa)
SEM13310.1Protein of unknown function. (79 aa)
Your Current Organism:
Acinetobacter sp. DSM 11652
NCBI taxonomy Id: 346222
Other names: A. sp. DSM 11652, Acinetobacter hebeiensis
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