(45 nodes) Epithelial structure maintenance network (Anopheles melas)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A182UJP2	Uncharacterized protein. (910 aa)
	A0A182TPN4	Uncharacterized protein. (2755 aa)
	A0A182UI68	Uncharacterized protein. (282 aa)
	A0A182UHK8	Merlin (moesin-ezrin-radixin-like protein). (592 aa)
	A0A182UH63	Uncharacterized protein. (321 aa)
	A0A182UGV3	Uncharacterized protein. (207 aa)
	A0A182UFN6	Uncharacterized protein. (401 aa)
	A0A182UDV9	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (578 aa)
	A0A182UDA6	Ig-like domain-containing protein. (208 aa)
	A0A182UD86	Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (752 aa)
	A0A182UD11	Protein kinase domain-containing protein. (669 aa)
	A0A182UCQ2	Tyrosine-protein kinase. (598 aa)
	A0A182UBR6	Uncharacterized protein. (190 aa)
	A0A182UBB6	Uncharacterized protein. (115 aa)
	A0A182UAG0	Protein kinase domain-containing protein. (764 aa)
	A0A182U9M5	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (129 aa)
	A0A182U7Z9	Receptor protein-tyrosine kinase. (1421 aa)
	A0A182U6R1	Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1281 aa)
	A0A182U3A1	Uncharacterized protein. (247 aa)
	A0A182U351	C2H2-type domain-containing protein. (682 aa)
	A0A182U2B5	Uncharacterized protein. (145 aa)
	A0A182U203	ATG11 domain-containing protein. (1371 aa)
	A0A182U0E3	Uncharacterized protein. (66 aa)
	A0A182TZJ4	Uncharacterized protein. (382 aa)
	A0A182TZ89	Uncharacterized protein. (376 aa)
	A0A182TZ14	Uncharacterized protein. (1701 aa)
	A0A182TX08	Uncharacterized protein. (462 aa)
	A0A182TWH1	Integrin_alpha2 domain-containing protein. (411 aa)
	A0A182TV93	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (136 aa)
	A0A182TU40	Uncharacterized protein. (289 aa)
	A0A182TT42	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (158 aa)
	A0A182TSQ5	Collagen IV NC1 domain-containing protein. (1766 aa)
	A0A182TRW1	Uncharacterized protein. (629 aa)
	A0A182TRC9	Uncharacterized protein. (1256 aa)
	A0A182TQX4	I/LWEQ domain-containing protein. (428 aa)
	A0A182TMR4	PDZ domain-containing protein. (305 aa)
	A0A182TMK7	Uncharacterized protein. (173 aa)
	A0A182TMB6	LAM_G_DOMAIN domain-containing protein. (451 aa)
	A0A182TM93	Uncharacterized protein. (519 aa)
	A0A182TKM3	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (986 aa)
	A0A182TIH0	Integrin beta; Belongs to the integrin beta chain family. (837 aa)
	A0A182TH77	Protein kinase domain-containing protein. (210 aa)
	A0A182TGI3	Rhomboid-like protein. (358 aa)
	A0A182TG95	Rho-GAP domain-containing protein. (777 aa)
	A0A182TF76	Uncharacterized protein. (348 aa)

Your Current Organism:

Anopheles melas

NCBI taxonomy Id: 34690
Other names: A. melas

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A182TF76	A0A182TG95	Uncharacterized protein.	Rho-GAP domain-containing protein.	0.927
A0A182TF76	A0A182TPN4	Uncharacterized protein.	Uncharacterized protein.	0.493
A0A182TF76	A0A182TQX4	Uncharacterized protein.	I/LWEQ domain-containing protein.	0.493
A0A182TG95	A0A182TF76	Rho-GAP domain-containing protein.	Uncharacterized protein.	0.927
A0A182TG95	A0A182TPN4	Rho-GAP domain-containing protein.	Uncharacterized protein.	0.493
A0A182TG95	A0A182TQX4	Rho-GAP domain-containing protein.	I/LWEQ domain-containing protein.	0.493
A0A182TGI3	A0A182U7Z9	Rhomboid-like protein.	Receptor protein-tyrosine kinase.	0.616
A0A182TH77	A0A182TIH0	Protein kinase domain-containing protein.	Integrin beta; Belongs to the integrin beta chain family.	0.669
A0A182TH77	A0A182TPN4	Protein kinase domain-containing protein.	Uncharacterized protein.	0.639
A0A182TH77	A0A182TQX4	Protein kinase domain-containing protein.	I/LWEQ domain-containing protein.	0.639
A0A182TH77	A0A182TT42	Protein kinase domain-containing protein.	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	0.440
A0A182TH77	A0A182TWH1	Protein kinase domain-containing protein.	Integrin_alpha2 domain-containing protein.	0.481
A0A182TH77	A0A182U6R1	Protein kinase domain-containing protein.	Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family.	0.481
A0A182TH77	A0A182U7Z9	Protein kinase domain-containing protein.	Receptor protein-tyrosine kinase.	0.818
A0A182TH77	A0A182U9M5	Protein kinase domain-containing protein.	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	0.440
A0A182TH77	A0A182UAG0	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.544
A0A182TH77	A0A182UBB6	Protein kinase domain-containing protein.	Uncharacterized protein.	0.481
A0A182TH77	A0A182UCQ2	Protein kinase domain-containing protein.	Tyrosine-protein kinase.	0.867
A0A182TH77	A0A182UD11	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.489
A0A182TH77	A0A182UD86	Protein kinase domain-containing protein.	Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family.	0.481