(122 nodes) Phagosome network (Anopheles melas)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A182UF18	Uncharacterized protein; Belongs to the CD36 family. (506 aa)
	A0A182UFC2	Uncharacterized protein. (425 aa)
	A0A182UGE6	t-SNARE coiled-coil homology domain-containing protein. (338 aa)
	A0A182UGP4	Uncharacterized protein. (550 aa)
	A0A182UH31	Poly [ADP-ribose] polymerase. (848 aa)
	A0A182UH37	Nitric oxide synthase; Produces nitric oxide (NO). (1090 aa)
	A0A182UHK2	Uncharacterized protein. (320 aa)
	A0A182UHW3	Uncharacterized protein. (1066 aa)
	A0A182UIJ7	Uncharacterized protein. (210 aa)
	A0A182UIV6	Uncharacterized protein. (341 aa)
	A0A182UJ46	Uncharacterized protein. (133 aa)
	A0A182UJJ7	Uncharacterized protein. (368 aa)
	A0A182UJN9	Uncharacterized protein; Belongs to the CD36 family. (531 aa)
	A0A182UJY4	Uncharacterized protein. (2223 aa)
	A0A182UK67	Uncharacterized protein; Belongs to the DEAD box helicase family. (507 aa)
	A0A182UK85	Uncharacterized protein. (1766 aa)
	A0A182UKH2	WD_REPEATS_REGION domain-containing protein. (526 aa)
	A0A182UKN1	Uncharacterized protein. (390 aa)
	A0A182UL42	Uncharacterized protein. (1313 aa)
	A0A182ULM9	Uncharacterized protein. (376 aa)
	A0A182ULN0	Uncharacterized protein. (376 aa)
	A0A182TIV2	t-SNARE coiled-coil homology domain-containing protein. (288 aa)
	A0A182TJM1	Coronin; Belongs to the WD repeat coronin family. (542 aa)
	A0A182TJQ3	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (456 aa)
	A0A182TK22	Uncharacterized protein. (864 aa)
	A0A182TK28	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (460 aa)
	A0A182TK91	Uncharacterized protein. (175 aa)
	A0A182TKC5	Uncharacterized protein. (70 aa)
	A0A182TKH2	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (498 aa)
	A0A182TKK9	Uncharacterized protein. (3530 aa)
	A0A182TKT8	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded. (777 aa)
	A0A182TL15	Uncharacterized protein. (184 aa)
	A0A182TL66	Uncharacterized protein. (196 aa)
	A0A182TL92	Uncharacterized protein; Belongs to the CD36 family. (507 aa)
	A0A182TLA2	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (116 aa)
	A0A182TLG7	Uncharacterized protein. (126 aa)
	A0A182TLH2	Uncharacterized protein. (216 aa)
	A0A182TLU1	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
	A0A182TMA3	Uncharacterized protein. (595 aa)
	A0A182TME3	Uncharacterized protein. (455 aa)
	A0A182TMG4	Uncharacterized protein. (359 aa)
	A0A182TMZ6	Tr-type G domain-containing protein. (687 aa)
	A0A182TNR8	PHD domain-containing protein. (1085 aa)
	A0A182TNS9	Uncharacterized protein. (2234 aa)
	A0A182TP75	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (432 aa)
	A0A182TPS1	Uncharacterized protein; Belongs to the CD36 family. (609 aa)
	A0A182TQQ9	Uncharacterized protein; Belongs to the CD36 family. (562 aa)
	A0A182TRN4	INB domain-containing protein. (385 aa)
	A0A182TD76	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (428 aa)
	A0A182TDC6	Uncharacterized protein. (226 aa)
	A0A182TEK7	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (441 aa)
	A0A182TER9	Uncharacterized protein. (241 aa)
	A0A182TFA6	Uncharacterized protein. (207 aa)
	A0A182TFD4	Uncharacterized protein; Belongs to the CD36 family. (409 aa)
	A0A182TFK0	Uncharacterized protein. (228 aa)
	A0A182TFZ9	Uncharacterized protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (588 aa)
	A0A182TGQ6	Uncharacterized protein. (192 aa)
	A0A182TGR6	Uncharacterized protein. (442 aa)
	A0A182TGU8	V-ATPase_H_C domain-containing protein. (360 aa)
	A0A182TH85	Uncharacterized protein. (236 aa)
	A0A182THS5	Uncharacterized protein. (629 aa)
	A0A182TIH0	Integrin beta; Belongs to the integrin beta chain family. (837 aa)
	A0A182TIQ6	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (458 aa)
	A0A182UEL6	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (510 aa)
	A0A182UEE0	Uncharacterized protein. (144 aa)
	A0A182UDX3	Uncharacterized protein; Belongs to the CD36 family. (457 aa)
	A0A182UDV9	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (578 aa)
	A0A182UDQ6	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (831 aa)
	A0A182UD30	Fe2OG dioxygenase domain-containing protein. (318 aa)
	A0A182UCM8	Calreticulin. (406 aa)
	A0A182UCI3	Uncharacterized protein. (396 aa)
	A0A182UC56	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (298 aa)
	A0A182UBU4	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
	A0A182UBK8	Uncharacterized protein. (126 aa)
	A0A182UBJ9	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (833 aa)
	A0A182UB29	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (240 aa)
	A0A182UAW0	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (465 aa)
	A0A182UAD0	Uncharacterized protein. (263 aa)
	A0A182U9Y6	t-SNARE coiled-coil homology domain-containing protein. (259 aa)
	A0A182U911	Uncharacterized protein. (1236 aa)
	A0A182U8P2	Uncharacterized protein; Belongs to the tubulin family. (1194 aa)
	A0A182U8P0	Uncharacterized protein. (614 aa)
	A0A182U7Y3	Uncharacterized protein. (3765 aa)
	A0A182U7M0	Uncharacterized protein; Belongs to the peptidase C1 family. (296 aa)
	A0A182U751	Uncharacterized protein; Belongs to the CD36 family. (452 aa)
	A0A182U6A2	Uncharacterized protein. (1046 aa)
	A0A182U5H7	Uncharacterized protein. (376 aa)
	A0A182U5C7	zf-Tim10_DDP domain-containing protein. (123 aa)
	A0A182U4L6	Uncharacterized protein; Belongs to the V-ATPase proteolipid subunit family. (208 aa)
	A0A182U3B5	Uncharacterized protein. (376 aa)
	A0A182U309	Plug_translocon domain-containing protein. (476 aa)
	A0A182U240	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (139 aa)
	A0A182U1E7	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (403 aa)
	A0A182U0U9	Uncharacterized protein. (195 aa)
	A0A182U0G0	Uncharacterized protein. (376 aa)
	A0A182U0E3	Uncharacterized protein. (66 aa)
	A0A182U0C6	Uncharacterized protein. (480 aa)
	A0A182U010	Uncharacterized protein; Belongs to the CD36 family. (522 aa)
	A0A182TZM2	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (849 aa)
	A0A182TZE3	Coronin; Belongs to the WD repeat coronin family. (706 aa)
	A0A182TZ17	Uncharacterized protein. (179 aa)
	A0A182TYQ9	Uncharacterized protein. (520 aa)
	A0A182TYA2	Uncharacterized protein; Belongs to the peptidase C1 family. (303 aa)
	A0A182TY53	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (127 aa)
	A0A182TXY7	Uncharacterized protein. (132 aa)
	A0A182TXM7	Uncharacterized protein. (376 aa)
	A0A182TX37	WD_REPEATS_REGION domain-containing protein. (648 aa)
	A0A182TWX5	PHD-type domain-containing protein. (376 aa)
	A0A182TWT6	Vacuolar H+ ATPase AC45 accessory subunit. (388 aa)
	A0A182TWN5	Uncharacterized protein. (107 aa)
	A0A182TWD7	Uncharacterized protein. (564 aa)
	A0A182TVY9	Uncharacterized protein. (1650 aa)
	A0A182TVK7	Uncharacterized protein; Belongs to the CD36 family. (463 aa)
	A0A182TVI0	Uncharacterized protein. (657 aa)
	A0A182TV74	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (385 aa)
	A0A182TUU9	Uncharacterized protein. (223 aa)
	A0A182TUQ6	Uncharacterized protein; Belongs to the CD36 family. (516 aa)
	A0A182TUH0	WD_REPEATS_REGION domain-containing protein. (608 aa)
	A0A182TSS7	Longin domain-containing protein; Belongs to the synaptobrevin family. (137 aa)
	A0A182TS83	Uncharacterized protein. (357 aa)
	A0A182TS26	WD_REPEATS_REGION domain-containing protein. (919 aa)
	A0A182TRS6	Uncharacterized protein. (204 aa)

Your Current Organism:

Anopheles melas

NCBI taxonomy Id: 34690
Other names: A. melas

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A182TD76	A0A182TFZ9	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Uncharacterized protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.891
A0A182TD76	A0A182TGQ6	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Uncharacterized protein.	0.498
A0A182TD76	A0A182TGR6	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Uncharacterized protein.	0.602
A0A182TD76	A0A182TIQ6	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.967
A0A182TD76	A0A182TJQ3	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	0.831
A0A182TD76	A0A182TK22	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Uncharacterized protein.	0.602
A0A182TD76	A0A182TK28	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.973
A0A182TD76	A0A182TKK9	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Uncharacterized protein.	0.443
A0A182TD76	A0A182TL15	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Uncharacterized protein.	0.873
A0A182TD76	A0A182TL66	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Uncharacterized protein.	0.498
A0A182TD76	A0A182TLU1	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.908
A0A182TD76	A0A182TMG4	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Uncharacterized protein.	0.602
A0A182TD76	A0A182TNS9	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Uncharacterized protein.	0.443
A0A182TD76	A0A182TRS6	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Uncharacterized protein.	0.603
A0A182TD76	A0A182TS26	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	WD_REPEATS_REGION domain-containing protein.	0.602
A0A182TD76	A0A182TS83	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Uncharacterized protein.	0.571
A0A182TD76	A0A182TUH0	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	WD_REPEATS_REGION domain-containing protein.	0.602
A0A182TD76	A0A182TVI0	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Uncharacterized protein.	0.862
A0A182TD76	A0A182TWD7	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Uncharacterized protein.	0.443
A0A182TD76	A0A182TWN5	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Uncharacterized protein.	0.613