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NP_4924A NP_4924A acs4 acs4 acs3 acs3 NP_5076A NP_5076A hmgB hmgB panB panB acs2 acs2 acs1 acs1 acd12 acd12 acd10 acd10 NP_3860A NP_3860A coaD coaD acd6 acd6 NP_2856A NP_2856A mvk mvk NP_2700A NP_2700A acd2 acd2 acd1 acd1 oxdhA2 oxdhA2 hmgA1 hmgA1 acd9 acd9 NP_1690A NP_1690A acd5 acd5 mvaD mvaD coaBC coaBC mce mce panD panD panE panE NP_0848A NP_0848A NP_0844A NP_0844A oxdhA1 oxdhA1 hmgA2 hmgA2 acs5 acs5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NP_4924AThioesterase domain protein. (142 aa)
acs4acyl-CoA synthetase. (657 aa)
acs3acyl-CoA synthetase. (662 aa)
NP_5076AUPF0218 family protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). (178 aa)
hmgBhydroxymethylglutaryl-CoA synthase. (445 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (268 aa)
acs2acyl-CoA synthetase. (560 aa)
acs1acyl-CoA synthetase. (655 aa)
acd12acyl-CoA dehydrogenase. (406 aa)
acd10acyl-CoA dehydrogenase. (384 aa)
NP_3860AHD family hydrolase. (147 aa)
coaDPhosphopantetheine adenylyltransferase. (163 aa)
acd6acyl-CoA dehydrogenase. (384 aa)
NP_2856ADRTGG domain protein. (352 aa)
mvkMevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (329 aa)
NP_2700AThioesterase domain protein. (159 aa)
acd2acyl-CoA dehydrogenase. (379 aa)
acd1glutaryl-CoA dehydrogenase. (387 aa)
oxdhA2Probable 2-oxoacid dehydrogenase E1 component alpha subunit. (379 aa)
hmgA1hydroxymethylglutaryl-CoA reductase (NADPH); Belongs to the HMG-CoA reductase family. (402 aa)
acd9acyl-CoA dehydrogenase. (374 aa)
NP_1690AUncharacterized protein. (287 aa)
acd5acyl-CoA dehydrogenase. (381 aa)
mvaDPhosphomevalonate decarboxylase. (324 aa)
coaBCPhosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase. (385 aa)
mcemethylmalonyl-CoA epimerase. (127 aa)
panDAspartate 1-decarboxylase; Catalyzes the decarboxylation of L-aspartate to produce beta- alanine; Belongs to the group II decarboxylase family. MfnA subfamily. (350 aa)
panE2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (299 aa)
NP_0848A4-phosphopantoate--beta-alanine ligase. (246 aa)
NP_0844APantoate kinase. (272 aa)
oxdhA12-oxo-3-methylvalerate dehydrogenase E1 component alpha subunit. (374 aa)
hmgA2hydroxymethylglutaryl-CoA reductase (NADPH). (539 aa)
acs5acyl-CoA synthetase. (544 aa)
Your Current Organism:
Natronomonas pharaonis
NCBI taxonomy Id: 348780
Other names: N. pharaonis DSM 2160, Natronomonas pharaonis ATCC 35678, Natronomonas pharaonis DSM 2160, Natronomonas pharaonis Gabara, Natronomonas pharaonis JCM 8858, Natronomonas pharaonis str. DSM 2160, Natronomonas pharaonis strain DSM 2160
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