STRINGSTRING
acs5 acs5 citB1 citB1 mdh mdh ppsA ppsA mmcA2 mmcA2 mce mce korA korA korB1 korB1 citB2 citB2 folD folD acaB8 acaB8 mmcA1 mmcA1 icd icd acaB1 acaB1 mmcB mmcB hbd2 hbd2 acaB3 acaB3 acaB4 acaB4 acaB7 acaB7 fumC fumC porB porB porA porA acs1 acs1 acs2 acs2 sdhA sdhA sdhB sdhB sdhD sdhD sdhC sdhC sucD sucD sucC sucC acs3 acs3 acs4 acs4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
acs5acyl-CoA synthetase. (544 aa)
citB1Aconitate hydratase. (657 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. (304 aa)
ppsAPhosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (759 aa)
mmcA2methylmalonyl-CoA mutase subunit A. (556 aa)
mcemethylmalonyl-CoA epimerase. (127 aa)
korAOxoglutarate--ferredoxin oxidoreductase alpha subunit. (587 aa)
korB1Oxoglutarate--ferredoxin oxidoreductase beta subunit. (289 aa)
citB2Aconitate hydratase. (917 aa)
folDMethylenetetrahydrofolate dehydrogenase / methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (297 aa)
acaB8acetyl-CoA C-acyltransferase. (388 aa)
mmcA1methylmalonyl-CoA mutase subunit A. (561 aa)
icdIsocitrate dehydrogenase (NADP). (418 aa)
acaB1acetyl-CoA C-acyltransferase. (393 aa)
mmcBmethylmalonyl-CoA mutase subunit B (cobalamin-binding subunit). (138 aa)
hbd23-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (651 aa)
acaB3acetyl-CoA C-acyltransferase. (389 aa)
acaB4acetyl-CoA C-acetyltransferase. (384 aa)
acaB7acetyl-CoA C-acetyltransferase catalytic subunit. (384 aa)
fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (471 aa)
porBPyruvate--ferredoxin oxidoreductase beta subunit. (311 aa)
porAPyruvate--ferredoxin oxidoreductase alpha subunit. (629 aa)
acs1acyl-CoA synthetase. (655 aa)
acs2acyl-CoA synthetase. (560 aa)
sdhASuccinate dehydrogenase subunit A; Deleted EC_number 1.3.99.1. (611 aa)
sdhBSuccinate dehydrogenase subunit B; Deleted EC_number 1.3.99.1. (287 aa)
sdhDSuccinate dehydrogenase subunit D; Deleted EC_number 1.3.99.1. (121 aa)
sdhCSuccinate dehydrogenase subunit C; Deleted EC_number 1.3.99.1. (130 aa)
sucDsuccinate--CoA ligase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (289 aa)
sucCsuccinate--CoA ligase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (380 aa)
acs3acyl-CoA synthetase. (662 aa)
acs4acyl-CoA synthetase. (657 aa)
Your Current Organism:
Natronomonas pharaonis
NCBI taxonomy Id: 348780
Other names: N. pharaonis DSM 2160, Natronomonas pharaonis ATCC 35678, Natronomonas pharaonis DSM 2160, Natronomonas pharaonis Gabara, Natronomonas pharaonis JCM 8858, Natronomonas pharaonis str. DSM 2160, Natronomonas pharaonis strain DSM 2160
Server load: low (14%) [HD]