(16 nodes) Synthesis of very long-chain fatty acyl-CoAs network (Exophiala xenobiotica)

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Your Input:
	PV05_04272	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. (336 aa)
	PV05_00158	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (239 aa)
	PV05_09803	BZIP domain-containing protein. (319 aa)
	PV05_07262	Elongation of fatty acids protein. (725 aa)
	PV05_04491	Uncharacterized protein. (237 aa)
	PV05_11034	S5A_REDUCTASE domain-containing protein. (307 aa)
	PV05_11778	Uncharacterized protein. (364 aa)
	PV05_08198	Uncharacterized protein. (232 aa)
	PV05_10614	BZIP domain-containing protein. (234 aa)
	PV05_06604	Elongation of fatty acids protein. (341 aa)
	PV05_10519	Uncharacterized protein. (289 aa)
	PV05_00805	BZIP domain-containing protein. (297 aa)
	PV05_01412	Uncharacterized protein. (267 aa)
	PV05_01157	BZIP domain-containing protein. (241 aa)
	PV05_02221	Elongation of fatty acids protein. (353 aa)
	PV05_02879	Uncharacterized protein. (315 aa)

Your Current Organism:

Exophiala xenobiotica

NCBI taxonomy Id: 348802
Other names: CBS 118157, E. xenobiotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PV05_00158	PV05_01412	A0A0D2C4T3	A0A0D2F001	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Uncharacterized protein.	0.565
PV05_00158	PV05_02221	A0A0D2C4T3	A0A0D2FC55	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Elongation of fatty acids protein.	0.817
PV05_00158	PV05_02879	A0A0D2C4T3	A0A0D2FE65	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Uncharacterized protein.	0.867
PV05_00158	PV05_04272	A0A0D2C4T3	A0A0D2BSV6	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids.	0.876
PV05_00158	PV05_04491	A0A0D2C4T3	A0A0D2D037	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Uncharacterized protein.	0.565
PV05_00158	PV05_06604	A0A0D2C4T3	A0A0D2EFL6	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Elongation of fatty acids protein.	0.817
PV05_00158	PV05_07262	A0A0D2C4T3	A0A0D2CXR2	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Elongation of fatty acids protein.	0.736
PV05_00158	PV05_08198	A0A0D2C4T3	A0A0D2EB66	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Uncharacterized protein.	0.565
PV05_00158	PV05_10519	A0A0D2C4T3	A0A0D2EVF1	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Uncharacterized protein.	0.876
PV05_00158	PV05_11034	A0A0D2C4T3	A0A0D2E1M9	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	S5A_REDUCTASE domain-containing protein.	0.950
PV05_00158	PV05_11778	A0A0D2C4T3	A0A0D2E3X1	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Uncharacterized protein.	0.406
PV05_00805	PV05_01412	A0A0D2EY05	A0A0D2F001	BZIP domain-containing protein.	Uncharacterized protein.	0.565
PV05_00805	PV05_02221	A0A0D2EY05	A0A0D2FC55	BZIP domain-containing protein.	Elongation of fatty acids protein.	0.593
PV05_00805	PV05_02879	A0A0D2EY05	A0A0D2FE65	BZIP domain-containing protein.	Uncharacterized protein.	0.840
PV05_00805	PV05_04272	A0A0D2EY05	A0A0D2BSV6	BZIP domain-containing protein.	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids.	0.768
PV05_00805	PV05_04491	A0A0D2EY05	A0A0D2D037	BZIP domain-containing protein.	Uncharacterized protein.	0.565
PV05_00805	PV05_06604	A0A0D2EY05	A0A0D2EFL6	BZIP domain-containing protein.	Elongation of fatty acids protein.	0.593
PV05_00805	PV05_07262	A0A0D2EY05	A0A0D2CXR2	BZIP domain-containing protein.	Elongation of fatty acids protein.	0.593
PV05_00805	PV05_08198	A0A0D2EY05	A0A0D2EB66	BZIP domain-containing protein.	Uncharacterized protein.	0.565
PV05_00805	PV05_10519	A0A0D2EY05	A0A0D2EVF1	BZIP domain-containing protein.	Uncharacterized protein.	0.768