(32 nodes) Steroid biosynthesis, and Endogenous sterols network (Exophiala xenobiotica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	PV05_10732	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (380 aa)
	PV05_09346	FAD-binding PCMH-type domain-containing protein. (524 aa)
	PV05_09640	Uncharacterized protein; Belongs to the cytochrome P450 family. (533 aa)
	PV05_06164	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (749 aa)
	PV05_06305	Uncharacterized protein. (578 aa)
	PV05_05196	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (296 aa)
	PV05_02502	Uncharacterized protein; Belongs to the cytochrome P450 family. (600 aa)
	PV05_03089	Methyltranfer_dom domain-containing protein. (302 aa)
	PV05_03663	GFA domain-containing protein. (290 aa)
	PV05_10906	Uncharacterized protein. (485 aa)
	PV05_07945	Zn(2)-C6 fungal-type domain-containing protein. (741 aa)
	PV05_07223	EXPERA domain-containing protein. (259 aa)
	PV05_04273	Uncharacterized protein. (145 aa)
	PV05_11598	Uncharacterized protein; Belongs to the cytochrome P450 family. (533 aa)
	PV05_09585	3Beta_HSD domain-containing protein. (435 aa)
	PV05_10680	Uncharacterized protein. (175 aa)
	PV05_07403	Uncharacterized protein; Belongs to the cytochrome P450 family. (570 aa)
	PV05_10977	Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol. (449 aa)
	PV05_09691	Epimerase domain-containing protein. (439 aa)
	PV05_10264	FAD_binding_3 domain-containing protein. (658 aa)
	PV05_00458	Methyltransf_11 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family. (343 aa)
	PV05_00894	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (248 aa)
	PV05_06703	Uncharacterized protein. (250 aa)
	PV05_07011	Uncharacterized protein. (214 aa)
	PV05_01915	Farnesyl-diphosphate farnesyltransferase. (479 aa)
	PV05_07269	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (393 aa)
	PV05_06000	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (359 aa)
	PV05_06025	SE domain-containing protein. (492 aa)
	PV05_03472	Epimerase domain-containing protein. (405 aa)
	PV05_03556	Uncharacterized protein. (443 aa)
	PV05_04051	Uncharacterized protein; Belongs to the cytochrome P450 family. (506 aa)
	PV05_01265	Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol. (385 aa)

Your Current Organism:

Exophiala xenobiotica

NCBI taxonomy Id: 348802
Other names: CBS 118157, E. xenobiotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PV05_00458	PV05_00894	A0A0D2EWV1	A0A0D2F171	Methyltransf_11 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.449
PV05_00458	PV05_01915	A0A0D2EWV1	A0A0D2F4C2	Methyltransf_11 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.	Farnesyl-diphosphate farnesyltransferase.	0.869
PV05_00458	PV05_02502	A0A0D2EWV1	A0A0D2BZR6	Methyltransf_11 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.415
PV05_00458	PV05_03556	A0A0D2EWV1	A0A0D2FG58	Methyltransf_11 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.	Uncharacterized protein.	0.922
PV05_00458	PV05_04051	A0A0D2EWV1	A0A0D2FHI9	Methyltransf_11 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.847
PV05_00458	PV05_04273	A0A0D2EWV1	A0A0D2CZJ3	Methyltransf_11 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.	Uncharacterized protein.	0.819
PV05_00458	PV05_05196	A0A0D2EWV1	A0A0D2BVR3	Methyltransf_11 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.	0.763
PV05_00458	PV05_06000	A0A0D2EWV1	A0A0D2FBK8	Methyltransf_11 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.	0.906
PV05_00458	PV05_06164	A0A0D2EWV1	A0A0D2BMJ3	Methyltransf_11 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.	0.873
PV05_00458	PV05_06305	A0A0D2EWV1	A0A0D2BMY1	Methyltransf_11 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.	Uncharacterized protein.	0.856
PV05_00458	PV05_07011	A0A0D2EWV1	A0A0D2F434	Methyltransf_11 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.	Uncharacterized protein.	0.943
PV05_00458	PV05_07269	A0A0D2EWV1	A0A0D2F4Z9	Methyltransf_11 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.	0.763
PV05_00458	PV05_07403	A0A0D2EWV1	A0A0D2EKC9	Methyltransf_11 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.415
PV05_00458	PV05_07945	A0A0D2EWV1	A0A0D2CQM9	Methyltransf_11 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.	Zn(2)-C6 fungal-type domain-containing protein.	0.415
PV05_00458	PV05_09346	A0A0D2EWV1	A0A0D2BEF4	Methyltransf_11 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.	FAD-binding PCMH-type domain-containing protein.	0.595
PV05_00458	PV05_09585	A0A0D2EWV1	A0A0D2E5Q3	Methyltransf_11 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.	3Beta_HSD domain-containing protein.	0.713
PV05_00458	PV05_09640	A0A0D2EWV1	A0A0D2BF71	Methyltransf_11 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.847
PV05_00458	PV05_09691	A0A0D2EWV1	A0A0D2ESX9	Methyltransf_11 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.	Epimerase domain-containing protein.	0.713
PV05_00458	PV05_10732	A0A0D2EWV1	A0A0D2BA01	Methyltransf_11 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.	0.763
PV05_00458	PV05_10906	A0A0D2EWV1	A0A0D2CH60	Methyltransf_11 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.	Uncharacterized protein.	0.855