77 items (Exophiala xenobiotica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV05_10519	Uncharacterized protein. (289 aa)
	PV05_06076	SAT domain-containing protein. (446 aa)
	PV05_05864	PKS_AT domain-containing protein; Belongs to the fungal fatty acid synthetase subunit beta family. (2088 aa)
	PV05_05771	AMP-binding domain-containing protein. (630 aa)
	PV05_05488	Uncharacterized protein. (965 aa)
	PV05_04654	Carrier domain-containing protein. (2522 aa)
	PV05_04541	PKS_ER domain-containing protein. (409 aa)
	PV05_04791	Carrier domain-containing protein. (2617 aa)
	PV05_07041	Uncharacterized protein. (293 aa)
	PV05_07385	Uncharacterized protein. (1430 aa)
	PV05_07039	Uncharacterized protein. (226 aa)
	PV05_06972	Uncharacterized protein. (986 aa)
	PV05_06604	Elongation of fatty acids protein. (341 aa)
	PV05_09269	Uncharacterized protein. (144 aa)
	PV05_07992	PKS_AT domain-containing protein. (385 aa)
	PV05_08198	Uncharacterized protein. (232 aa)
	PV05_10612	Uncharacterized protein. (270 aa)
	PV05_09926	PNPLA domain-containing protein. (521 aa)
	PV05_09287	AMP-binding domain-containing protein. (645 aa)
	PV05_11105	PNPLA domain-containing protein. (397 aa)
	PV05_10894	AMP-binding domain-containing protein. (678 aa)
	PV05_11356	Uncharacterized protein. (2291 aa)
	PV05_11034	S5A_REDUCTASE domain-containing protein. (307 aa)
	PV05_10787	Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (419 aa)
	PV05_01928	Uncharacterized protein. (646 aa)
	PV05_01114	F-box domain-containing protein. (1208 aa)
	PV05_00911	Carrier domain-containing protein. (2572 aa)
	PV05_00906	Carrier domain-containing protein. (2106 aa)
	PV05_03533	Uncharacterized protein. (260 aa)
	PV05_03437	Uncharacterized protein. (641 aa)
	PV05_04695	PNPLA domain-containing protein. (1294 aa)
	PV05_04656	Carrier domain-containing protein. (2756 aa)
	PV05_04491	Uncharacterized protein. (237 aa)
	PV05_07262	Elongation of fatty acids protein. (725 aa)
	PV05_08651	PNPLA domain-containing protein. (576 aa)
	PV05_10662	Uncharacterized protein. (1165 aa)
	PV05_02127	Uncharacterized protein. (295 aa)
	PV05_01937	Uncharacterized protein. (437 aa)
	PV05_01841	Uncharacterized protein. (375 aa)
	PV05_01130	Uncharacterized protein. (1155 aa)
	PV05_00405	Uncharacterized protein. (485 aa)
	PV05_00158	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (239 aa)
	PV05_04160	Uncharacterized protein. (649 aa)
	PV05_03510	Uncharacterized protein. (245 aa)
	PV05_05865	Fatty acid synthase subunit alpha; Belongs to the thiolase-like superfamily. Fungal fatty acid synthetase subunit alpha family. (1868 aa)
	PV05_05311	AB hydrolase-1 domain-containing protein. (467 aa)
	PV05_04272	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. (336 aa)
	PV05_06932	Ceramide very long chain fatty acid hydroxylase; Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids. Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2; Belongs to the sterol desaturase family. SCS7 subfamily. (394 aa)
	PV05_06233	Uncharacterized protein. (2180 aa)
	PV05_09282	Carrier domain-containing protein. (2606 aa)
	PV05_10330	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (271 aa)
	PV05_09559	Uncharacterized protein. (262 aa)
	PV05_11268	Uncharacterized protein. (418 aa)
	PV05_07621	Uncharacterized protein. (270 aa)
	PV05_01564	Uncharacterized protein. (2154 aa)
	PV05_01559	Holo-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Fungal fatty acid synthetase subunit alpha family. (1814 aa)
	PV05_01246	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (139 aa)
	PV05_00752	Uncharacterized protein. (246 aa)
	PV05_03135	Uncharacterized protein. (645 aa)
	PV05_02879	Uncharacterized protein. (315 aa)
	PV05_02221	Elongation of fatty acids protein. (353 aa)
	PV05_05629	Uncharacterized protein. (489 aa)
	PV05_06835	Neutral ceramidase. (770 aa)
	PV05_01270	ACB domain-containing protein. (102 aa)
	PV05_01143	Uncharacterized protein. (406 aa)
	PV05_01803	Uncharacterized protein. (460 aa)
	PV05_09119	Uncharacterized protein. (280 aa)
	PV05_01558	PKS_AT domain-containing protein; Belongs to the fungal fatty acid synthetase subunit beta family. (2053 aa)
	PV05_00631	Uncharacterized protein. (449 aa)
	PV05_01412	Uncharacterized protein. (267 aa)
	PV05_01272	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. (480 aa)
	PV05_01245	Uncharacterized protein. (455 aa)
	PV05_08636	Uncharacterized protein. (460 aa)
	PV05_04120	PNPLA domain-containing protein. (381 aa)
	PV05_04076	3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (430 aa)
	PV05_03954	Uncharacterized protein. (251 aa)
	PV05_00663	Uncharacterized protein. (574 aa)

Your Current Organism:

Exophiala xenobiotica

NCBI taxonomy Id: 348802
Other names: CBS 118157, E. xenobiotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PV05_00158	PV05_00752	A0A0D2C4T3	A0A0D2FK90	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Uncharacterized protein.	0.565
PV05_00158	PV05_01272	A0A0D2C4T3	A0A0D2EZK2	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	0.775
PV05_00158	PV05_01412	A0A0D2C4T3	A0A0D2F001	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Uncharacterized protein.	0.565
PV05_00158	PV05_02127	A0A0D2C4T3	A0A0D2CAS3	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Uncharacterized protein.	0.565
PV05_00158	PV05_02221	A0A0D2C4T3	A0A0D2FC55	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Elongation of fatty acids protein.	0.817
PV05_00158	PV05_02879	A0A0D2C4T3	A0A0D2FE65	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Uncharacterized protein.	0.867
PV05_00158	PV05_04272	A0A0D2C4T3	A0A0D2BSV6	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids.	0.876
PV05_00158	PV05_04491	A0A0D2C4T3	A0A0D2D037	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Uncharacterized protein.	0.565
PV05_00158	PV05_06604	A0A0D2C4T3	A0A0D2EFL6	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Elongation of fatty acids protein.	0.817
PV05_00158	PV05_07262	A0A0D2C4T3	A0A0D2CXR2	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Elongation of fatty acids protein.	0.736
PV05_00158	PV05_08198	A0A0D2C4T3	A0A0D2EB66	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Uncharacterized protein.	0.565
PV05_00158	PV05_09269	A0A0D2C4T3	A0A0D2EE88	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Uncharacterized protein.	0.565
PV05_00158	PV05_09559	A0A0D2C4T3	A0A0D2BEW4	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Uncharacterized protein.	0.565
PV05_00158	PV05_10330	A0A0D2C4T3	A0A0D2BHB0	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.565
PV05_00158	PV05_10519	A0A0D2C4T3	A0A0D2EVF1	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Uncharacterized protein.	0.876
PV05_00158	PV05_11034	A0A0D2C4T3	A0A0D2E1M9	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	S5A_REDUCTASE domain-containing protein.	0.950
PV05_00405	PV05_00906	A0A0D2C5H8	A0A0D2DEF9	Uncharacterized protein.	Carrier domain-containing protein.	0.712
PV05_00405	PV05_00911	A0A0D2C5H8	A0A0D2DEG4	Uncharacterized protein.	Carrier domain-containing protein.	0.712
PV05_00405	PV05_01246	A0A0D2C5H8	A0A0D2FLS3	Uncharacterized protein.	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	0.622
PV05_00405	PV05_01272	A0A0D2C5H8	A0A0D2EZK2	Uncharacterized protein.	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	0.505