43 items (Exophiala xenobiotica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV05_04990	Non-specific serine/threonine protein kinase. (640 aa)
	PV05_01729	Uncharacterized protein. (1554 aa)
	PV05_02193	Uncharacterized protein. (825 aa)
	PV05_05639	Fungal_trans domain-containing protein. (687 aa)
	PV05_05079	Polyubiquitin. (305 aa)
	PV05_01670	Uncharacterized protein. (588 aa)
	PV05_00675	Serine/threonine-protein phosphatase. (329 aa)
	PV05_00791	Uncharacterized protein. (1024 aa)
	PV05_07883	Zn(2)-C6 fungal-type domain-containing protein. (738 aa)
	PV05_03618	Uncharacterized protein. (170 aa)
	PV05_09373	Ubiquitin-40S ribosomal protein S27a. (154 aa)
	PV05_12007	Uncharacterized protein. (818 aa)
	PV05_04668	Guanylate cyclase domain-containing protein. (360 aa)
	PV05_06874	MIT domain-containing protein. (1187 aa)
	PV05_08900	Non-specific serine/threonine protein kinase. (907 aa)
	PV05_08706	Uncharacterized protein. (493 aa)
	PV05_08291	Uncharacterized protein. (448 aa)
	PV05_08521	PIPK domain-containing protein. (350 aa)
	PV05_08033	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (279 aa)
	MDM34	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. (611 aa)
	PV05_10884	Uncharacterized protein. (620 aa)
	PV05_11205	Uncharacterized protein. (793 aa)
	PV05_00541	OTU domain-containing protein. (414 aa)
	PV05_03881	WD_REPEATS_REGION domain-containing protein. (546 aa)
	PV05_02478	Metallophos domain-containing protein. (453 aa)
	PV05_05210	PIPK domain-containing protein. (969 aa)
	PV05_06588	VEFS-Box domain-containing protein. (897 aa)
	PV05_06556	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (662 aa)
	PV05_09062	Zn(2)-C6 fungal-type domain-containing protein. (761 aa)
	PV05_08826	Protein kinase domain-containing protein. (869 aa)
	PV05_11433	Uncharacterized protein. (154 aa)
	PV05_02022	Uncharacterized protein. (1479 aa)
	GUF1	Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. (660 aa)
	PV05_01271	U-box domain-containing protein. (287 aa)
	PV05_00728	Uncharacterized protein. (104 aa)
	PV05_02213	Uncharacterized protein. (184 aa)
	PV05_05818	Rap-GAP domain-containing protein. (1443 aa)
	PV05_05670	Uncharacterized protein. (1304 aa)
	PV05_04584	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2491 aa)
	PV05_07578	Fork-head domain-containing protein. (415 aa)
	PV05_06209	Uncharacterized protein. (176 aa)
	PV05_09061	BZIP domain-containing protein. (494 aa)
	PV05_08811	Non-specific serine/threonine protein kinase. (628 aa)

Your Current Organism:

Exophiala xenobiotica

NCBI taxonomy Id: 348802
Other names: CBS 118157, E. xenobiotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GUF1	PV05_00728	A0A0D2C9E0	A0A0D2C6N6	Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.	Uncharacterized protein.	0.625
GUF1	PV05_05079	A0A0D2C9E0	A0A0D2F8Q2	Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.	Polyubiquitin.	0.603
GUF1	PV05_09061	A0A0D2C9E0	A0A0D2BLT8	Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.	BZIP domain-containing protein.	0.625
GUF1	PV05_09373	A0A0D2C9E0	A0A0D2ERZ6	Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.	Ubiquitin-40S ribosomal protein S27a.	0.625
MDM34	PV05_00675	A0A0D2E393	A0A0D2F0L7	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	Serine/threonine-protein phosphatase.	0.417
MDM34	PV05_02478	A0A0D2E393	A0A0D2D6H2	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	Metallophos domain-containing protein.	0.417
MDM34	PV05_05639	A0A0D2E393	A0A0D2FAK7	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	Fungal_trans domain-containing protein.	0.862
MDM34	PV05_07883	A0A0D2E393	A0A0D2EWK5	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	Zn(2)-C6 fungal-type domain-containing protein.	0.862
MDM34	PV05_08033	A0A0D2E393	A0A0D2EAN0	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.862
MDM34	PV05_09062	A0A0D2E393	A0A0D2CTZ1	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	Zn(2)-C6 fungal-type domain-containing protein.	0.862
PV05_00541	PV05_00728	A0A0D2DDB9	A0A0D2C6N6	OTU domain-containing protein.	Uncharacterized protein.	0.625
PV05_00541	PV05_05079	A0A0D2DDB9	A0A0D2F8Q2	OTU domain-containing protein.	Polyubiquitin.	0.764
PV05_00541	PV05_09061	A0A0D2DDB9	A0A0D2BLT8	OTU domain-containing protein.	BZIP domain-containing protein.	0.682
PV05_00541	PV05_09373	A0A0D2DDB9	A0A0D2ERZ6	OTU domain-containing protein.	Ubiquitin-40S ribosomal protein S27a.	0.682
PV05_00675	MDM34	A0A0D2F0L7	A0A0D2E393	Serine/threonine-protein phosphatase.	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	0.417
PV05_00675	PV05_00728	A0A0D2F0L7	A0A0D2C6N6	Serine/threonine-protein phosphatase.	Uncharacterized protein.	0.620
PV05_00675	PV05_00791	A0A0D2F0L7	A0A0D2EXZ2	Serine/threonine-protein phosphatase.	Uncharacterized protein.	0.462
PV05_00675	PV05_02193	A0A0D2F0L7	A0A0D2FC30	Serine/threonine-protein phosphatase.	Uncharacterized protein.	0.887
PV05_00675	PV05_04584	A0A0D2F0L7	A0A0D2BTR9	Serine/threonine-protein phosphatase.	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.864
PV05_00675	PV05_04990	A0A0D2F0L7	A0A0D2D1N2	Serine/threonine-protein phosphatase.	Non-specific serine/threonine protein kinase.	0.646