(12 nodes) Androgen biosynthesis network (Exophiala xenobiotica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV05_00752	Uncharacterized protein. (246 aa)
	PV05_02879	Uncharacterized protein. (315 aa)
	PV05_01412	Uncharacterized protein. (267 aa)
	PV05_10519	Uncharacterized protein. (289 aa)
	PV05_06089	S5A_REDUCTASE domain-containing protein. (315 aa)
	PV05_04272	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. (336 aa)
	PV05_10330	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (271 aa)
	PV05_09559	Uncharacterized protein. (262 aa)
	PV05_02127	Uncharacterized protein. (295 aa)
	PV05_04491	Uncharacterized protein. (237 aa)
	PV05_08198	Uncharacterized protein. (232 aa)
	PV05_09269	Uncharacterized protein. (144 aa)

Your Current Organism:

Exophiala xenobiotica

NCBI taxonomy Id: 348802
Other names: CBS 118157, E. xenobiotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PV05_00752	PV05_06089	A0A0D2FK90	A0A0D2EPS5	Uncharacterized protein.	S5A_REDUCTASE domain-containing protein.	0.468
PV05_01412	PV05_06089	A0A0D2F001	A0A0D2EPS5	Uncharacterized protein.	S5A_REDUCTASE domain-containing protein.	0.468
PV05_02127	PV05_06089	A0A0D2CAS3	A0A0D2EPS5	Uncharacterized protein.	S5A_REDUCTASE domain-containing protein.	0.468
PV05_02879	PV05_04272	A0A0D2FE65	A0A0D2BSV6	Uncharacterized protein.	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids.	0.747
PV05_02879	PV05_06089	A0A0D2FE65	A0A0D2EPS5	Uncharacterized protein.	S5A_REDUCTASE domain-containing protein.	0.695
PV05_02879	PV05_10519	A0A0D2FE65	A0A0D2EVF1	Uncharacterized protein.	Uncharacterized protein.	0.751
PV05_04272	PV05_02879	A0A0D2BSV6	A0A0D2FE65	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids.	Uncharacterized protein.	0.747
PV05_04272	PV05_06089	A0A0D2BSV6	A0A0D2EPS5	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids.	S5A_REDUCTASE domain-containing protein.	0.695
PV05_04491	PV05_06089	A0A0D2D037	A0A0D2EPS5	Uncharacterized protein.	S5A_REDUCTASE domain-containing protein.	0.468
PV05_06089	PV05_00752	A0A0D2EPS5	A0A0D2FK90	S5A_REDUCTASE domain-containing protein.	Uncharacterized protein.	0.468
PV05_06089	PV05_01412	A0A0D2EPS5	A0A0D2F001	S5A_REDUCTASE domain-containing protein.	Uncharacterized protein.	0.468
PV05_06089	PV05_02127	A0A0D2EPS5	A0A0D2CAS3	S5A_REDUCTASE domain-containing protein.	Uncharacterized protein.	0.468
PV05_06089	PV05_02879	A0A0D2EPS5	A0A0D2FE65	S5A_REDUCTASE domain-containing protein.	Uncharacterized protein.	0.695
PV05_06089	PV05_04272	A0A0D2EPS5	A0A0D2BSV6	S5A_REDUCTASE domain-containing protein.	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids.	0.695
PV05_06089	PV05_04491	A0A0D2EPS5	A0A0D2D037	S5A_REDUCTASE domain-containing protein.	Uncharacterized protein.	0.468
PV05_06089	PV05_08198	A0A0D2EPS5	A0A0D2EB66	S5A_REDUCTASE domain-containing protein.	Uncharacterized protein.	0.468
PV05_06089	PV05_09269	A0A0D2EPS5	A0A0D2EE88	S5A_REDUCTASE domain-containing protein.	Uncharacterized protein.	0.468
PV05_06089	PV05_09559	A0A0D2EPS5	A0A0D2BEW4	S5A_REDUCTASE domain-containing protein.	Uncharacterized protein.	0.468
PV05_06089	PV05_10330	A0A0D2EPS5	A0A0D2BHB0	S5A_REDUCTASE domain-containing protein.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.468
PV05_06089	PV05_10519	A0A0D2EPS5	A0A0D2EVF1	S5A_REDUCTASE domain-containing protein.	Uncharacterized protein.	0.695