STRINGSTRING
PV05_07881 PV05_07881 PV05_00395 PV05_00395 PV05_01284 PV05_01284 PV05_07520 PV05_07520 PV05_11995 PV05_11995 PV05_05735 PV05_05735 PV05_00822 PV05_00822 PV05_00162 PV05_00162 PV05_00917 PV05_00917 PV05_01223 PV05_01223
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PV05_07881Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (1043 aa)
PV05_00395Telo_bind domain-containing protein. (645 aa)
PV05_01284Histone H2B; Belongs to the histone H2B family. (141 aa)
PV05_07520AAA_23 domain-containing protein. (1306 aa)
PV05_11995Uncharacterized protein. (1619 aa)
PV05_05735Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. (285 aa)
PV05_00822Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (548 aa)
PV05_00162Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2926 aa)
PV05_00917Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (746 aa)
PV05_01223HUN domain-containing protein. (596 aa)
Your Current Organism:
Exophiala xenobiotica
NCBI taxonomy Id: 348802
Other names: CBS 118157, E. xenobiotica
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