10 items (Exophiala xenobiotica) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Your Input:
	PV05_07881	Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (1043 aa)
	PV05_00395	Telo_bind domain-containing protein. (645 aa)
	PV05_01284	Histone H2B; Belongs to the histone H2B family. (141 aa)
	PV05_07520	AAA_23 domain-containing protein. (1306 aa)
	PV05_11995	Uncharacterized protein. (1619 aa)
	PV05_05735	Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. (285 aa)
	PV05_00822	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (548 aa)
	PV05_00162	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2926 aa)
	PV05_00917	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (746 aa)
	PV05_01223	HUN domain-containing protein. (596 aa)

Your Current Organism:

Exophiala xenobiotica

NCBI taxonomy Id: 348802
Other names: CBS 118157, E. xenobiotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PV05_00162	PV05_00822	A0A0D2EZ01	A0A0D2EY24	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.825
PV05_00162	PV05_00917	A0A0D2EZ01	A0A0D2F191	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.991
PV05_00162	PV05_01284	A0A0D2EZ01	A0A0D2C868	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.	Histone H2B; Belongs to the histone H2B family.	0.633
PV05_00162	PV05_07520	A0A0D2EZ01	A0A0D2CYJ9	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.	AAA_23 domain-containing protein.	0.986
PV05_00395	PV05_00917	A0A0D2C5H1	A0A0D2F191	Telo_bind domain-containing protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.654
PV05_00395	PV05_01284	A0A0D2C5H1	A0A0D2C868	Telo_bind domain-containing protein.	Histone H2B; Belongs to the histone H2B family.	0.719
PV05_00395	PV05_07520	A0A0D2C5H1	A0A0D2CYJ9	Telo_bind domain-containing protein.	AAA_23 domain-containing protein.	0.643
PV05_00822	PV05_00162	A0A0D2EY24	A0A0D2EZ01	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.	0.825
PV05_00822	PV05_00917	A0A0D2EY24	A0A0D2F191	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.699
PV05_00822	PV05_01284	A0A0D2EY24	A0A0D2C868	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Histone H2B; Belongs to the histone H2B family.	0.804
PV05_00822	PV05_05735	A0A0D2EY24	A0A0D2ENS8	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.	0.483
PV05_00822	PV05_07520	A0A0D2EY24	A0A0D2CYJ9	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	AAA_23 domain-containing protein.	0.738
PV05_00822	PV05_11995	A0A0D2EY24	A0A0D2E6M8	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Uncharacterized protein.	0.713
PV05_00917	PV05_00162	A0A0D2F191	A0A0D2EZ01	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.	0.991
PV05_00917	PV05_00395	A0A0D2F191	A0A0D2C5H1	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Telo_bind domain-containing protein.	0.654
PV05_00917	PV05_00822	A0A0D2F191	A0A0D2EY24	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.699
PV05_00917	PV05_01284	A0A0D2F191	A0A0D2C868	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Histone H2B; Belongs to the histone H2B family.	0.696
PV05_00917	PV05_07520	A0A0D2F191	A0A0D2CYJ9	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	AAA_23 domain-containing protein.	0.999
PV05_00917	PV05_11995	A0A0D2F191	A0A0D2E6M8	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Uncharacterized protein.	0.407
PV05_01223	PV05_05735	A0A0D2F2B7	A0A0D2ENS8	HUN domain-containing protein.	Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.	0.942