101 items (Exophiala xenobiotica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV05_11150	Serine/threonine-protein kinase pef1; Belongs to the protein kinase superfamily. (407 aa)
	PV05_11318	t-SNARE coiled-coil homology domain-containing protein. (229 aa)
	PV05_09886	Zn(2)-C6 fungal-type domain-containing protein. (679 aa)
	PV05_09943	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (402 aa)
	PV05_08516	Uncharacterized protein. (965 aa)
	PV05_08811	Non-specific serine/threonine protein kinase. (628 aa)
	PV05_07485	WD_REPEATS_REGION domain-containing protein. (1451 aa)
	PV05_04584	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2491 aa)
	PV05_04916	Protein kinase domain-containing protein. (827 aa)
	PV05_03820	S1 motif domain-containing protein. (313 aa)
	PV05_04106	Autophagy-related protein 13; Belongs to the ATG13 family. Fungi subfamily. (922 aa)
	PV05_00117	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology. (830 aa)
	PV05_00423	Uncharacterized protein. (353 aa)
	PV05_01105	Phosphatidylinositol 3-kinase VPS34. (940 aa)
	PV05_01912	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (389 aa)
	PV05_02065	Autophagy_act_C domain-containing protein. (214 aa)
	PV05_11204	cAMP-dependent protein kinase type 2; Belongs to the protein kinase superfamily. (427 aa)
	PV05_11226	Autophagy-related protein; Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation; Belongs to the ATG22 family. (643 aa)
	PV05_11919	Autophagy-related protein. (118 aa)
	PV05_12005	CNH domain-containing protein. (1020 aa)
	PV05_09771	Protein Ras-2, variant. (241 aa)
	PV05_10624	Uncharacterized protein. (212 aa)
	PV05_09167	Uncharacterized protein. (827 aa)
	PV05_06376	Aminotran_1_2 domain-containing protein. (508 aa)
	PV05_07259	Uncharacterized protein. (2030 aa)
	PV05_04680	Uncharacterized protein. (528 aa)
	PV05_04990	Non-specific serine/threonine protein kinase. (640 aa)
	PV05_02380	Mannan endo-1,6-alpha-mannosidase. (462 aa)
	PV05_03545	G-patch domain-containing protein. (648 aa)
	PV05_03886	Uncharacterized protein. (292 aa)
	PV05_00466	Kinase; Belongs to the inositol phosphokinase (IPK) family. (396 aa)
	PV05_00583	ATG16 domain-containing protein. (207 aa)
	PV05_00701	Uncharacterized protein. (433 aa)
	PV05_01285	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. (523 aa)
	PV05_01440	Uncharacterized protein. (220 aa)
	PV05_01457	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (415 aa)
	PV05_01888	Uncharacterized protein. (524 aa)
	PV05_10805	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. (173 aa)
	PV05_11295	Mannan endo-1,6-alpha-mannosidase. (467 aa)
	PV05_11417	Uncharacterized protein. (607 aa)
	PV05_11610	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (590 aa)
	PV05_11585	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA. (697 aa)
	PV05_10040	Vps8 domain-containing protein. (1563 aa)
	PV05_09389	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (970 aa)
	PV05_10474	Uncharacterized protein. (1476 aa)
	PV05_10489	Autophagy-related protein 3. (371 aa)
	PV05_10578	Subtilisin-like protease; Belongs to the peptidase S8 family. (496 aa)
	PV05_09933	Uncharacterized protein. (558 aa)
	PV05_07716	Uncharacterized protein. (883 aa)
	PV05_07734	Uncharacterized protein. (361 aa)
	PV05_07723	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (406 aa)
	PV05_07818	Response regulatory domain-containing protein. (463 aa)
	PV05_08817	Uncharacterized protein; Belongs to the actin family. (527 aa)
	PV05_08291	Uncharacterized protein. (448 aa)
	PV05_08805	ATG11 domain-containing protein. (1500 aa)
	PV05_08900	Non-specific serine/threonine protein kinase. (907 aa)
	PV05_06937	Zn(2)-C6 fungal-type domain-containing protein. (638 aa)
	PV05_07201	Uncharacterized protein. (309 aa)
	PV05_04641	Uncharacterized protein. (697 aa)
	PV05_04766	Lipase_3 domain-containing protein. (351 aa)
	PV05_10920	Myotubularin phosphatase domain-containing protein. (889 aa)
	PV05_05469	Pep3_Vps18 domain-containing protein. (963 aa)
	PV05_05634	Uncharacterized protein; Belongs to the synaptobrevin family. (198 aa)
	PV05_05905	Uncharacterized protein; Belongs to the protein kinase superfamily. (458 aa)
	PV05_05725	Mannan endo-1,6-alpha-mannosidase. (458 aa)
	PV05_05839	Uncharacterized protein. (844 aa)
	PV05_09512	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. (316 aa)
	PV05_09586	Uncharacterized protein. (1979 aa)
	PV05_09638	Protein kinase domain-containing protein. (985 aa)
	PV05_09720	Uncharacterized protein. (186 aa)
	PV05_03721	Uncharacterized protein. (496 aa)
	PV05_00084	Uncharacterized protein. (842 aa)
	PV05_00168	Ras-like protein. (218 aa)
	PV05_00206	Kinase; Belongs to the inositol phosphokinase (IPK) family. (1281 aa)
	PV05_00280	Aminotran_1_2 domain-containing protein. (685 aa)
	PV05_00318	Mannan endo-1,6-alpha-mannosidase. (459 aa)
	PV05_08254	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (496 aa)
	PV05_08280	Protein kinase domain-containing protein. (1270 aa)
	PV05_00883	E3 ubiquitin-protein ligase PEP5. (984 aa)
	PV05_00198	Uncharacterized protein. (686 aa)
	PV05_01255	Vacuolar protease A; Belongs to the peptidase A1 family. (397 aa)
	PV05_00431	Uncharacterized protein; Belongs to the actin family. (439 aa)
	PV05_00626	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (414 aa)
	PV05_00675	Serine/threonine-protein phosphatase. (329 aa)
	PV05_01704	Mannan endo-1,6-alpha-mannosidase. (461 aa)
	PV05_01714	Non-specific serine/threonine protein kinase. (914 aa)
	PV05_01026	Uncharacterized protein. (1649 aa)
	PV05_06358	Uncharacterized protein. (1307 aa)
	PV05_02151	Aa_trans domain-containing protein. (762 aa)
	PV05_07191	CNH domain-containing protein. (1197 aa)
	PV05_04213	Aa_trans domain-containing protein. (569 aa)
	PV05_05273	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (660 aa)
	PV05_05474	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (496 aa)
	PV05_05543	Uncharacterized protein. (1041 aa)
	PV05_02696	Uncharacterized protein. (584 aa)
	PV05_03846	SPX domain-containing protein. (921 aa)
	PV05_04139	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...] (727 aa)
	PV05_00584	Uncharacterized protein. (205 aa)
	PV05_01226	Uncharacterized protein. (270 aa)
	PV05_01631	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (248 aa)
	PV05_01692	Uncharacterized protein. (276 aa)

Your Current Organism:

Exophiala xenobiotica

NCBI taxonomy Id: 348802
Other names: CBS 118157, E. xenobiotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PV05_00084	PV05_05474	A0A0D2EVS9	A0A0D2FA05	Uncharacterized protein.	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.	0.465
PV05_00117	PV05_00584	A0A0D2C4N4	A0A0D2FJP1	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	Uncharacterized protein.	0.970
PV05_00117	PV05_00883	A0A0D2C4N4	A0A0D2EY73	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	E3 ubiquitin-protein ligase PEP5.	0.997
PV05_00117	PV05_01026	A0A0D2C4N4	A0A0D2F1L9	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	Uncharacterized protein.	0.416
PV05_00117	PV05_01105	A0A0D2C4N4	A0A0D2C7M0	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	Phosphatidylinositol 3-kinase VPS34.	0.437
PV05_00117	PV05_03886	A0A0D2C4N4	A0A0D2DAW8	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	Uncharacterized protein.	0.418
PV05_00117	PV05_05273	A0A0D2C4N4	A0A0D2F9D5	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	0.997
PV05_00117	PV05_05469	A0A0D2C4N4	A0A0D2EN58	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	Pep3_Vps18 domain-containing protein.	0.997
PV05_00117	PV05_05634	A0A0D2C4N4	A0A0D2ENM2	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	Uncharacterized protein; Belongs to the synaptobrevin family.	0.953
PV05_00117	PV05_06358	A0A0D2C4N4	A0A0D2F200	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	Uncharacterized protein.	0.997
PV05_00117	PV05_07191	A0A0D2C4N4	A0A0D2F4P4	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	CNH domain-containing protein.	0.995
PV05_00117	PV05_08516	A0A0D2C4N4	A0A0D2BK99	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	Uncharacterized protein.	0.970
PV05_00117	PV05_10040	A0A0D2C4N4	A0A0D2E756	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	Vps8 domain-containing protein.	0.940
PV05_00117	PV05_11318	A0A0D2C4N4	A0A0D2BBZ7	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	t-SNARE coiled-coil homology domain-containing protein.	0.966
PV05_00117	PV05_11417	A0A0D2C4N4	A0A0D2E2M9	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	Uncharacterized protein.	0.568
PV05_00117	PV05_11610	A0A0D2C4N4	A0A0D2E3F2	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	0.849
PV05_00117	PV05_12005	A0A0D2C4N4	A0A0D2CKS6	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	CNH domain-containing protein.	0.998
PV05_00168	PV05_00584	A0A0D2EVY7	A0A0D2FJP1	Ras-like protein.	Uncharacterized protein.	0.594
PV05_00168	PV05_00675	A0A0D2EVY7	A0A0D2F0L7	Ras-like protein.	Serine/threonine-protein phosphatase.	0.702
PV05_00168	PV05_01440	A0A0D2EVY7	A0A0D2DG68	Ras-like protein.	Uncharacterized protein.	0.416