(13 nodes) Phenylalanine, tyrosine and tryptophan biosynthesis, and Cyclic nucleotide-binding domain network (Leuconostoc citreum)

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	LCK_00695	Phosphate/sulphate permease. (181 aa)
	aroE	Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (281 aa)
	aroF	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; COG2876E. (331 aa)
	aroB	3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (360 aa)
	aroC	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (392 aa)
	aroA	3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (431 aa)
	tyrA	Prephenate dehydrogenase; COG0287E. (280 aa)
	aroK	Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (267 aa)
	LCK_00704	Protein of unknown function. (184 aa)
	aroD	3-dehydroquinate dehydratase; COG0710E. (294 aa)
	nox	NADH oxidase; COG0446R. (449 aa)
	flpA	FNR-like transcriptional regulator; COG0664T. (214 aa)
	hisC	Histidinol-phosphate aminotransferase; COG0079E; TIGR01141; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (354 aa)

Your Current Organism:

Leuconostoc citreum

NCBI taxonomy Id: 349519
Other names: L. citreum KM20, Leuconostoc citreum KM20, Leuconostoc citreum str. KM20, Leuconostoc citreum strain KM20

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LCK_00695	aroA	LCK_00695	LCK_00701	Phosphate/sulphate permease.	3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.	0.400
LCK_00695	aroD	LCK_00695	LCK_00705	Phosphate/sulphate permease.	3-dehydroquinate dehydratase; COG0710E.	0.400
LCK_00695	aroE	LCK_00695	LCK_00697	Phosphate/sulphate permease.	Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).	0.547
LCK_00695	aroF	LCK_00695	LCK_00698	Phosphate/sulphate permease.	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; COG2876E.	0.401
LCK_00695	flpA	LCK_00695	LCK_00940	Phosphate/sulphate permease.	FNR-like transcriptional regulator; COG0664T.	0.596
LCK_00704	aroA	LCK_00704	LCK_00701	Protein of unknown function.	3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.	0.904
LCK_00704	aroB	LCK_00704	LCK_00699	Protein of unknown function.	3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.	0.718
LCK_00704	aroC	LCK_00704	LCK_00700	Protein of unknown function.	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	0.879
LCK_00704	aroD	LCK_00704	LCK_00705	Protein of unknown function.	3-dehydroquinate dehydratase; COG0710E.	0.814
LCK_00704	aroE	LCK_00704	LCK_00697	Protein of unknown function.	Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).	0.685
LCK_00704	aroF	LCK_00704	LCK_00698	Protein of unknown function.	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; COG2876E.	0.752
LCK_00704	aroK	LCK_00704	LCK_00703	Protein of unknown function.	Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.	0.914
LCK_00704	tyrA	LCK_00704	LCK_00702	Protein of unknown function.	Prephenate dehydrogenase; COG0287E.	0.849
aroA	LCK_00695	LCK_00701	LCK_00695	3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.	Phosphate/sulphate permease.	0.400
aroA	LCK_00704	LCK_00701	LCK_00704	3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.	Protein of unknown function.	0.904
aroA	aroB	LCK_00701	LCK_00699	3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.	3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.	0.989
aroA	aroC	LCK_00701	LCK_00700	3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	0.998
aroA	aroD	LCK_00701	LCK_00705	3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.	3-dehydroquinate dehydratase; COG0710E.	0.830
aroA	aroE	LCK_00701	LCK_00697	3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.	Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).	0.912
aroA	aroF	LCK_00701	LCK_00698	3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; COG2876E.	0.770