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LCK_00051 | Ser/Thr protein phosphatase family protein; COG0737F; Belongs to the 5'-nucleotidase family. (605 aa) | ||||
asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (365 aa) | ||||
LCK_00158 | dUTPase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. (179 aa) | ||||
gmk1 | Guanylate kinase; COG0194F. (196 aa) | ||||
proB | Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (271 aa) | ||||
proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (415 aa) | ||||
LCK_00288 | Inosine-uridine nucleoside N-ribohydrolase; COG1957F. (330 aa) | ||||
birA | Biotin-(acetyl-CoA carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. (326 aa) | ||||
cdd | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (133 aa) | ||||
folC1 | Folylpolyglutamate synthase; COG0285H. (393 aa) | ||||
gmk2 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (198 aa) | ||||
LCK_00449 | GAF domain protein; COG1956T. (160 aa) | ||||
udk | Uridine kinase; COG0572F; TIGR00235. (210 aa) | ||||
upp | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (203 aa) | ||||
LCK_00551 | Homocysteine S-methyltransferase; COG2040E. (303 aa) | ||||
LCK_00587 | IMP dehydrogenase/GMP reductase; COG0516F. (390 aa) | ||||
LCK_00588 | IMP dehydrogenase/GMP reductase; COG0516F. (326 aa) | ||||
guaA | GMP synthase; Catalyzes the synthesis of GMP from XMP. (515 aa) | ||||
purE | Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (161 aa) | ||||
purK | Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase); Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (371 aa) | ||||
purC | Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; COG0152F; Belongs to the SAICAR synthetase family. (247 aa) | ||||
purS | Phosphoribosylformylglycinamidine synthase, PurS protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (88 aa) | ||||
purQ | Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with [...] (222 aa) | ||||
purL | Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL an [...] (746 aa) | ||||
purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (540 aa) | ||||
purM | Phosphoribosylaminoimidazole (AIR) synthetase; COG0150F. (345 aa) | ||||
purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (196 aa) | ||||
purH | Bifunctional purine biosynthesis protein PurH; COG0138F; TIGR00355. (508 aa) | ||||
LCK_00612 | NTP pyrophosphohydrolase including oxidative damage repair enzymes; COG0494LR. (153 aa) | ||||
purD | Phosphoribosylamine-glycine ligase; COG0151F; Belongs to the GARS family. (417 aa) | ||||
fhs | Formyltetrahydrofolate synthetase; COG2759F; Belongs to the formate--tetrahydrofolate ligase family. (554 aa) | ||||
LCK_00616 | Esterase; COG0627R. (267 aa) | ||||
LCK_00617 | Probable integral membrane transporter; COG0477GEPR. (405 aa) | ||||
purB | Adenylosuccinate lyase; COG0015F; TIGR00928; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (431 aa) | ||||
hpt1 | Hypoxanthine phosphoribosyltransferase; COG0634F; TIGR01203; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (187 aa) | ||||
LCK_00674 | GatB/Yqey domain-containing protein; COG1610S. (147 aa) | ||||
LCK_00675 | Protein of unknown function; COG2996S; Belongs to the CvfB family. (293 aa) | ||||
xerD | Site-specific recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (298 aa) | ||||
ribT | Putative reductase. (117 aa) | ||||
scpA | Segregation and condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. (258 aa) | ||||
scpB | Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. (200 aa) | ||||
rluB | 16S rRNA uridine-516 pseudouridylate synthase; COG1187J; similar to pseudouridylate synthase; Belongs to the pseudouridine synthase RsuA family. (249 aa) | ||||
LCK_00681 | Predicted membrane protein; Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins; Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family. (194 aa) | ||||
cmk | Cytidylate kinase; COG0283F; TIGR00017. (225 aa) | ||||
der | GTP-binding protein engA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (437 aa) | ||||
hbsU | Bacterial nucleoid DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (91 aa) | ||||
LCK_00687 | Protein of unknown function. (82 aa) | ||||
LCK_00688 | Related to diketogulonate reductase; COG0656R. (277 aa) | ||||
folA | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (166 aa) | ||||
LCK_00694 | Inosine-uridine nucleoside N-ribohydrolase; COG1957F. (331 aa) | ||||
LCK_00695 | Phosphate/sulphate permease. (181 aa) | ||||
aroE | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (281 aa) | ||||
aroF | 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; COG2876E. (331 aa) | ||||
aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (360 aa) | ||||
aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (392 aa) | ||||
aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (431 aa) | ||||
tyrA | Prephenate dehydrogenase; COG0287E. (280 aa) | ||||
aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (267 aa) | ||||
LCK_00704 | Protein of unknown function. (184 aa) | ||||
aroD | 3-dehydroquinate dehydratase; COG0710E. (294 aa) | ||||
LCK_00720 | Hypothetical protein. (184 aa) | ||||
LCK_00721 | Aspartokinase; COG0527E; Belongs to the aspartokinase family. (453 aa) | ||||
thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (291 aa) | ||||
hom | Homoserine dehydrogenase; COG0460E. (428 aa) | ||||
thrC | Threonine synthase; COG0498E; TIGR00260. (486 aa) | ||||
glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (410 aa) | ||||
fthC | 5-formyltetrahydrofolate cyclo-ligase; COG0212H; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (177 aa) | ||||
tnpA1 | Transposase; COG2826L. (305 aa) | ||||
kup | K+ transporter; Transport of potassium into the cell; Belongs to the HAK/KUP transporter (TC 2.A.72) family. (674 aa) | ||||
LCK_00760 | Transcriptional regulator; COG1316K. (414 aa) | ||||
LCK_00761 | Predicted permease; COG0628R. (331 aa) | ||||
ribD | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (347 aa) | ||||
ribE | Riboflavin synthase, alpha subunit; COG0307H; TIGR00187. (199 aa) | ||||
ribA | 3,4-dihydroxy-2-butanone 4-phosphate synthase; COG0807H; In the N-terminal section; belongs to the DHBP synthase family. (400 aa) | ||||
ribH | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (157 aa) | ||||
LCK_00766 | Predicted ATPase; COG0433R. (411 aa) | ||||
apbE | Membrane-associated lipoprotein involved in thiamine biosynthesis; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. (308 aa) | ||||
LCK_00768 | Predicted flavoprotein; COG0431R. (202 aa) | ||||
LCK_00769 | Predicted flavoprotein; COG0431R. (415 aa) | ||||
LCK_00771 | Putative penicillin-binding protein; COG1680V. (374 aa) | ||||
LCK_00772 | Predicted membrane protein; COG2261S. (81 aa) | ||||
LCK_00773 | Protein of unknown function. (184 aa) | ||||
LCK_00774 | Small integral membrane protein. (64 aa) | ||||
LCK_00775 | DUF322 domain-containing protein; COG1302S. (171 aa) | ||||
nox | NADH oxidase; COG0446R. (449 aa) | ||||
flpA | FNR-like transcriptional regulator; COG0664T. (214 aa) | ||||
LCK_00958 | Histone acetyltransferase HPA2; COG0454KR; similar to acetyltransferase. (189 aa) | ||||
tex | Transcriptional accessory protein; COG2183K. (733 aa) | ||||
LCK_00960 | Transcriptional antiterminator bglG:CAT RNA-binding region; COG3711K. (286 aa) | ||||
LCK_00961 | Glycoside hydrolase, family 1; COG2723G; Belongs to the glycosyl hydrolase 1 family. (394 aa) | ||||
LCK_00962 | Glycoside hydrolase, family 1; COG2723G; Belongs to the glycosyl hydrolase 1 family. (73 aa) | ||||
folP | Dihydropteroate synthase; COG0294H. (358 aa) | ||||
xtp | Xanthosine triphosphate pyrophosphatase; COG0127F. (199 aa) | ||||
folC2 | Folylpolyglutamate synthase; COG0285H; Belongs to the folylpolyglutamate synthase family. (423 aa) | ||||
folE | GTP cyclohydrolase; COG0302H. (191 aa) | ||||
folK | Hydroxymethylpterin pyrophosphokinase; COG0801H. (166 aa) | ||||
folB | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (128 aa) | ||||
LCK_00970 | Nicotinamide mononucleotide transporter PnuC. (239 aa) | ||||
LCK_00971 | Galactose mutarotase; COG2017G; similar to enzyme. (292 aa) | ||||
xerC | Site-specific recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (304 aa) | ||||
LCK_00973 | Protein of unknown function. (147 aa) | ||||
pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (209 aa) | ||||
pyrF | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (232 aa) | ||||
pyrDB | Dihydroorotate dehydrogenase B, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. (306 aa) | ||||
carB | Carbamoylphosphate synthase large subunit (split gene in MJ); COG0458EF. (1059 aa) | ||||
pyrAA1 | Carbamoylphosphate synthase small subunit; COG0505EF; Belongs to the CarA family. (362 aa) | ||||
pyrC | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (422 aa) | ||||
pyrB | Aspartate carbamoyltransferase; COG0540F; TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (303 aa) | ||||
argR-2 | Arginine repressor; Regulates arginine biosynthesis genes. (156 aa) | ||||
folC3 | Folylpolyglutamate synthase; COG0285H; Belongs to the folylpolyglutamate synthase family. (438 aa) | ||||
ilvE | Branched-chain amino acid aminotransferase; COG0115EH; TIGR01123. (346 aa) | ||||
ribF | Riboflavin biosynthesis protein RibF; COG0196H; TIGR00083; Belongs to the ribF family. (316 aa) | ||||
pyrAB | Carbamoylphosphate synthase large subunit (split gene in MJ); COG0458EF; Belongs to the CarB family. (840 aa) | ||||
pyrAA2 | Carbamoylphosphate synthase small subunit; COG0505EF; Belongs to the CarA family. (362 aa) | ||||
pyrR | Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase; Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. (175 aa) | ||||
LCK_01131 | Nucleoside phosphorylase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (224 aa) | ||||
argF | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (338 aa) | ||||
argH | Argininosuccinate lyase; COG0165E; TIGR00838. (462 aa) | ||||
argG | Argininosuccinate synthase; COG0137E; TIGR00032; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (410 aa) | ||||
apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (190 aa) | ||||
LCK_01221 | 5 nucleotidase, deoxy, cytosolic type C. (198 aa) | ||||
purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (427 aa) | ||||
hisC | Histidinol-phosphate aminotransferase; COG0079E; TIGR01141; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (354 aa) | ||||
smc | Barmotin; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1184 aa) | ||||
folD | 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (282 aa) | ||||
comEB | Deoxycytidylate deaminase; COG2131F. (161 aa) | ||||
thyA | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (319 aa) | ||||
metK | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (385 aa) | ||||
hpt2 | Hypoxanthine phosphoribosyltransferase; COG0634F; TIGR01203; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (179 aa) | ||||
LCK_01452 | Nitroreductase; COG0778C; Belongs to the flavin oxidoreductase frp family. (245 aa) | ||||
tdk | Thymidine kinase; COG1435F. (201 aa) | ||||
LCK_01475 | Methionine synthase II (cobalamin-independent); COG0620E. (375 aa) | ||||
luxS | LuxS protein involved in autoinducer AI2 synthesis; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (158 aa) | ||||
LCK_01477 | Methionine synthase II (cobalamin-independent); COG0620E. (373 aa) | ||||
LCK_01478 | Cystathionine beta-lyase; COG0626E. (383 aa) | ||||
metB | Cystathionine gamma-synthase; COG0626E. (369 aa) | ||||
metA | Homoserine trans-succinylase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (293 aa) | ||||
proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (255 aa) | ||||
tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (214 aa) | ||||
tadA | Cytosine/adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (169 aa) | ||||
LCK_01621 | Phosphatase; COG0737F; Belongs to the 5'-nucleotidase family. (501 aa) | ||||
pyrP | Xanthine/uracil Permease; COG2233F. (432 aa) | ||||
argC | Acetylglutamate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (347 aa) | ||||
argJ | Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (404 aa) | ||||
argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (245 aa) | ||||
argD | Ornithine/acetylornithine aminotransferase; COG4992E. (373 aa) | ||||
LCK_01694 | Aspartate/tyrosine/aromatic aminotransferase; COG0436E. (392 aa) | ||||
LCK_01695 | Predicted amidohydrolase; COG0388R. (263 aa) | ||||
xpt | Adenine/guanine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. (190 aa) |