STRINGSTRING
Amuc_0177 Amuc_0177 Amuc_0444 Amuc_0444 Amuc_0514 Amuc_0514 Amuc_0647 Amuc_0647 Amuc_0648 Amuc_0648 mraZ mraZ rsmH rsmH Amuc_0651 Amuc_0651 Amuc_0652 Amuc_0652 murE murE murF murF mraY mraY murD murD Amuc_0657 Amuc_0657 Amuc_0658 Amuc_0658 murG murG murB murB ddl ddl Amuc_0662 Amuc_0662 Amuc_0664 Amuc_0664 Amuc_0668 Amuc_0668 Amuc_0669 Amuc_0669 Amuc_0670 Amuc_0670 Amuc_0681 Amuc_0681 Amuc_0730 Amuc_0730 Amuc_0973 Amuc_0973 Amuc_0976 Amuc_0976 Amuc_0977 Amuc_0977 dtd dtd Amuc_1183 Amuc_1183 Amuc_1241 Amuc_1241 Amuc_1480 Amuc_1480 Amuc_1850 Amuc_1850 murA murA Amuc_2011 Amuc_2011 Amuc_2122 Amuc_2122
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Amuc_0177Peptidoglycan glycosyltransferase; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: aba:Acid345_1065 penicillin-binding protein 1A. (886 aa)
Amuc_0444Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; KEGG: pth:PTH_1876 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (307 aa)
Amuc_0514Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: gur:Gura_2858 peptidoglycan glycosyltransferase. (822 aa)
Amuc_0647PFAM: protein of unknown function UPF0126; KEGG: pat:Patl_4251 protein of unknown function UPF0126. (217 aa)
Amuc_0648PFAM: beta-lactamase domain protein; KEGG: pca:Pcar_1329 metal-dependent hydrolases of the beta-lactamase superfamily I. (259 aa)
mraZKEGG: cth:Cthe_0982 MraZ protein; Belongs to the MraZ family. (151 aa)
rsmHS-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (520 aa)
Amuc_0651Hypothetical protein. (114 aa)
Amuc_0652Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: gur:Gura_3980 peptidoglycan glycosyltransferase. (699 aa)
murEUDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (501 aa)
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (457 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (367 aa)
murDUDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (436 aa)
Amuc_0657PFAM: Peptidoglycan-binding LysM; KEGG: dde:Dde_3580 peptidoglycan-binding LysM. (266 aa)
Amuc_0658PFAM: cell cycle protein; KEGG: rrs:RoseRS_3785 cell division protein FtsW; Belongs to the SEDS family. (380 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (374 aa)
murBUDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurB family. (765 aa)
ddlD-alanine/D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (311 aa)
Amuc_0662Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein. (299 aa)
Amuc_0664PFAM: cell wall hydrolase/autolysin; KEGG: mxa:MXAN_3886 N-acetylmuramoyl-L-alanine amidase domain protein. (339 aa)
Amuc_0668Hypothetical protein. (373 aa)
Amuc_06692-alkenal reductase; PFAM: peptidase S1 and S6 chymotrypsin/Hap; KEGG: lbl:LBL_4184 trypsin-like serine protease. (524 aa)
Amuc_0670KEGG: sun:SUN_0311 serine protease. (526 aa)
Amuc_0681TIGRFAM: UDP-N-acetylmuramate; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: cte:CT1479 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase. (460 aa)
Amuc_0730KEGG: rpa:RPA1388 hypothetical protein. (341 aa)
Amuc_0973PFAM: Monogalactosyldiacylglycerol synthase; KEGG: drm:Dred_1966 monogalactosyldiacylglycerol synthase. (375 aa)
Amuc_0976KEGG: deb:DehaBAV1_0739 hypothetical protein. (189 aa)
Amuc_0977Hypothetical protein. (242 aa)
dtdD-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (150 aa)
Amuc_1183Hypothetical protein; KEGG: hmo:HM1_0712 septum formation initiator family protein. (122 aa)
Amuc_1241PFAM: glycosyl transferase family 51; KEGG: chy:CHY_1635 penicillin-binding protein, 1A family. (597 aa)
Amuc_1480PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; KEGG: cth:Cthe_3179 serine-type D-Ala-D-Ala carboxypeptidase. (323 aa)
Amuc_1850Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (367 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (425 aa)
Amuc_2011Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (368 aa)
Amuc_2122PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: sat:SYN_00304 multimodular transpeptidase-transglycosylase. (829 aa)
Your Current Organism:
Akkermansia muciniphila
NCBI taxonomy Id: 349741
Other names: A. muciniphila ATCC BAA-835, Akkermansia muciniphila ATCC BAA-835, Akkermansia muciniphila Muc, Akkermansia muciniphila str. ATCC BAA-835, Akkermansia muciniphila strain ATCC BAA-835, Akkermansia sp. Muc
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