STRINGSTRING
Amuc_0177 Amuc_0177 Amuc_0444 Amuc_0444 Amuc_0514 Amuc_0514 Amuc_0652 Amuc_0652 murE murE murF murF mraY mraY murD murD murG murG murB murB ddl ddl Amuc_0730 Amuc_0730 Amuc_1193 Amuc_1193 Amuc_1241 Amuc_1241 Amuc_1480 Amuc_1480 uppP uppP murA murA Amuc_2122 Amuc_2122
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Amuc_0177Peptidoglycan glycosyltransferase; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: aba:Acid345_1065 penicillin-binding protein 1A. (886 aa)
Amuc_0444Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; KEGG: pth:PTH_1876 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (307 aa)
Amuc_0514Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: gur:Gura_2858 peptidoglycan glycosyltransferase. (822 aa)
Amuc_0652Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: gur:Gura_3980 peptidoglycan glycosyltransferase. (699 aa)
murEUDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (501 aa)
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (457 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (367 aa)
murDUDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (436 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (374 aa)
murBUDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurB family. (765 aa)
ddlD-alanine/D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (311 aa)
Amuc_0730KEGG: rpa:RPA1388 hypothetical protein. (341 aa)
Amuc_1193Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (238 aa)
Amuc_1241PFAM: glycosyl transferase family 51; KEGG: chy:CHY_1635 penicillin-binding protein, 1A family. (597 aa)
Amuc_1480PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; KEGG: cth:Cthe_3179 serine-type D-Ala-D-Ala carboxypeptidase. (323 aa)
uppPUndecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (278 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (425 aa)
Amuc_2122PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: sat:SYN_00304 multimodular transpeptidase-transglycosylase. (829 aa)
Your Current Organism:
Akkermansia muciniphila
NCBI taxonomy Id: 349741
Other names: A. muciniphila ATCC BAA-835, Akkermansia muciniphila ATCC BAA-835, Akkermansia muciniphila Muc, Akkermansia muciniphila str. ATCC BAA-835, Akkermansia muciniphila strain ATCC BAA-835, Akkermansia sp. Muc
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