STRINGSTRING
Mflv_0017 Mflv_0017 Mflv_0018 Mflv_0018 Mflv_0079 Mflv_0079 Mflv_0375 Mflv_0375 Mflv_0507 Mflv_0507 Mflv_1079 Mflv_1079 Mflv_1080 Mflv_1080 Mflv_1081 Mflv_1081 Mflv_1082 Mflv_1082 Mflv_1083 Mflv_1083 Mflv_1085 Mflv_1085 Mflv_1086 Mflv_1086 Mflv_1313 Mflv_1313 Mflv_1314 Mflv_1314 egtA egtA egtB egtB egtC egtC egtD egtD egtE egtE Mflv_1448 Mflv_1448 Mflv_1449 Mflv_1449 Mflv_1450 Mflv_1450 Mflv_1454 Mflv_1454 Mflv_1455 Mflv_1455 Mflv_1456 Mflv_1456 Mflv_1457 Mflv_1457 Mflv_1950 Mflv_1950 Mflv_1951 Mflv_1951 Mflv_1952 Mflv_1952 Mflv_1953 Mflv_1953 Mflv_1955 Mflv_1955 Mflv_1956 Mflv_1956 Mflv_1957 Mflv_1957 fbpC fbpC Mflv_2857 Mflv_2857 Mflv_2858 Mflv_2858 Mflv_3135 Mflv_3135 Mflv_3136 Mflv_3136 Mflv_3137 Mflv_3137 potA potA Mflv_3166 Mflv_3166 Mflv_3167 Mflv_3167 Mflv_3168 Mflv_3168 Mflv_3273 Mflv_3273 Mflv_3361 Mflv_3361 Mflv_3362 Mflv_3362 Mflv_3363 Mflv_3363 Mflv_3452 Mflv_3452 Mflv_3453 Mflv_3453 Mflv_3454 Mflv_3454 Mflv_3456 Mflv_3456 Mflv_3457 Mflv_3457 Mflv_3560 Mflv_3560 Mflv_3643 Mflv_3643 Mflv_3667 Mflv_3667 Mflv_3668 Mflv_3668 Mflv_3671 Mflv_3671 Mflv_3672 Mflv_3672 Mflv_3673 Mflv_3673 Mflv_3674 Mflv_3674 Mflv_3675 Mflv_3675 Mflv_3676 Mflv_3676 Mflv_3677 Mflv_3677 Mflv_3678 Mflv_3678 Mflv_3679 Mflv_3679 Mflv_3680 Mflv_3680 Mflv_3681 Mflv_3681 Mflv_3812 Mflv_3812 Mflv_3879 Mflv_3879 Mflv_3880 Mflv_3880 Mflv_3881 Mflv_3881 Mflv_3882 Mflv_3882 Mflv_3883 Mflv_3883 Mflv_3884 Mflv_3884 Mflv_3885 Mflv_3885 Mflv_4126 Mflv_4126 Mflv_4127 Mflv_4127 Mflv_4128 Mflv_4128 Mflv_4129 Mflv_4129 ppk ppk Mflv_4278 Mflv_4278 Mflv_4700 Mflv_4700 Mflv_4701 Mflv_4701 Mflv_4702 Mflv_4702 Mflv_4703 Mflv_4703 Mflv_4704 Mflv_4704 Mflv_4944 Mflv_4944 Mflv_4945 Mflv_4945 Mflv_4946 Mflv_4946 Mflv_4948 Mflv_4948 Mflv_5091 Mflv_5091
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
Mflv_0017PFAM: major facilitator superfamily MFS_1; KEGG: mva:Mvan_0951 major facilitator superfamily MFS_1. (406 aa)
Mflv_0018KEGG: mva:Mvan_0950 conserved hypothetical protein. (416 aa)
Mflv_0079PFAM: Ppx/GppA phosphatase; KEGG: mva:Mvan_0833 Ppx/GppA phosphatase. (343 aa)
Mflv_0375PFAM: periplasmic binding protein; KEGG: mva:Mvan_0308 periplasmic binding protein. (315 aa)
Mflv_0507KEGG: sme:SMb20158 hypothetical ABC transporter periplasmic solute-binding protein. (399 aa)
Mflv_1079PFAM: pyridoxamine 5'-phosphate oxidase-related, FMN-binding; KEGG: mva:Mvan_5743 pyridoxamine 5'-phosphate oxidase-related, FMN-binding. (142 aa)
Mflv_1080KEGG: mva:Mvan_5742 extracellular solute-binding protein, family 1. (377 aa)
Mflv_1081PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mva:Mvan_5741 binding-protein-dependent transport systems inner membrane component. (283 aa)
Mflv_1082PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mva:Mvan_5740 binding-protein-dependent transport systems inner membrane component. (259 aa)
Mflv_1083PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: mva:Mvan_5739 ABC transporter-related protein. (347 aa)
Mflv_1085PFAM: pyridoxamine 5'-phosphate oxidase-related, FMN-binding; KEGG: mva:Mvan_5737 pyridoxamine 5'-phosphate oxidase-related, FMN-binding. (276 aa)
Mflv_1086KEGG: mva:Mvan_5736 conserved hypothetical protein. (366 aa)
Mflv_1313PFAM: cobalamin synthesis CobW domain protein; KEGG: mva:Mvan_5488 cobalamin synthesis CobW domain protein. (370 aa)
Mflv_1314KEGG: mva:Mvan_5487 conserved hypothetical protein. (224 aa)
egtAGlutamate--cysteine ligase, GCS2; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. (448 aa)
egtBProtein of unknown function DUF323; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. (429 aa)
egtCConserved hypothetical protein; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. (229 aa)
egtDConserved hypothetical protein; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family. (321 aa)
egtEAminotransferase, class V; Probably catalyzes the conversion of hercynylcysteine sulfoxide to ergothioneine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily. (370 aa)
Mflv_1448Arsenite efflux membrane protein ArsB; PFAM: Arsenical pump membrane protein; Citrate transporter; KEGG: mva:Mvan_5336 arsenical pump membrane protein; TC 3.A.4.1.1; TC 2.A.45.1.1. (411 aa)
Mflv_1449KEGG: mmc:Mmcs_4733 hypothetical protein. (305 aa)
Mflv_1450PFAM: major facilitator superfamily MFS_1; KEGG: mmc:Mmcs_4729 major facilitator superfamily MFS_1. (400 aa)
Mflv_1454PFAM: periplasmic solute binding protein; KEGG: mmc:Mmcs_4719 periplasmic solute binding protein. (339 aa)
Mflv_1455PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mmc:Mmcs_4718 ABC transporter related. (259 aa)
Mflv_1456PFAM: ABC-3 protein; KEGG: mva:Mvan_5318 ABC-3 protein. (291 aa)
Mflv_1457PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein, LacI; KEGG: mmc:Mmcs_4716 transcriptional regulator, LacI family. (365 aa)
Mflv_1950Dyp-type peroxidase family; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Belongs to the DyP-type peroxidase family. (451 aa)
Mflv_1951PFAM: protein of unknown function DUF451; KEGG: rha:RHA1_ro05774 hypothetical protein. (378 aa)
Mflv_1952PFAM: iron permease FTR1; KEGG: rha:RHA1_ro05775 possible membrane protein. (304 aa)
Mflv_1953KEGG: mmc:Mmcs_4241 putative conserved lipoprotein LpqU. (249 aa)
Mflv_1955PFAM: Septum formation initiator; KEGG: mmc:Mmcs_4239 septum formation initiator. (241 aa)
Mflv_1956PFAM: protein of unknown function DUF501; KEGG: mva:Mvan_4769 protein of unknown function DUF501. (164 aa)
Mflv_1957PFAM: Ppx/GppA phosphatase; KEGG: mmc:Mmcs_4237 Ppx/GppA phosphatase. (318 aa)
fbpCABC transporter related protein; Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system. (359 aa)
Mflv_2857PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mmc:Mmcs_1981 binding-protein-dependent transport systems inner membrane component. (536 aa)
Mflv_2858PFAM: extracellular solute-binding protein, family 1; KEGG: mmc:Mmcs_1982 extracellular solute-binding protein, family 1. (341 aa)
Mflv_3135PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mmc:Mmcs_2564 binding-protein-dependent transport systems inner membrane component. (285 aa)
Mflv_3136PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mmc:Mmcs_2565 binding-protein-dependent transport systems inner membrane component. (291 aa)
Mflv_3137PFAM: extracellular solute-binding protein, family 1; KEGG: mmc:Mmcs_2566 twin-arginine translocation pathway signal. (393 aa)
potASpermidine/putrescine ABC transporter ATPase subunit; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. (423 aa)
Mflv_3166PFAM: ABC-3 protein; KEGG: rha:RHA1_ro07269 possible ABC Mn(2+)/Zn(2+) transporter, permease component. (314 aa)
Mflv_3167PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rha:RHA1_ro07270 ABC metal transporter, ATP-binding component. (249 aa)
Mflv_3168PFAM: periplasmic solute binding protein; KEGG: rha:RHA1_ro07271 ABC metal ion transporter, substrate-binding protein; Belongs to the bacterial solute-binding protein 9 family. (313 aa)
Mflv_3273PFAM: protein of unknown function DUF328; KEGG: mmc:Mmcs_2696 protein of unknown function DUF328; Belongs to the UPF0246 family. (248 aa)
Mflv_3361PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: rha:RHA1_ro08545 Fe(3+)-transporting ATPase protein SfuC; Belongs to the ABC transporter superfamily. (364 aa)
Mflv_3362PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mva:Mvan_3092 binding-protein-dependent transport systems inner membrane component. (511 aa)
Mflv_3363PFAM: extracellular solute-binding protein, family 1; KEGG: rxy:Rxyl_1175 extracellular solute-binding protein, family 1. (342 aa)
Mflv_3452Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: mbo:Mb1944c ferric uptake regulation protein FurA (fur); Belongs to the Fur family. (145 aa)
Mflv_3453KEGG: mmc:Mmcs_2903 hypothetical protein. (442 aa)
Mflv_3454KEGG: mva:Mvan_3211 hypothetical protein. (372 aa)
Mflv_3456KEGG: mbo:Mb0351c probable lipoprotein LpqJ. (281 aa)
Mflv_3457KEGG: mmc:Mmcs_2904 hypothetical protein. (220 aa)
Mflv_3560KEGG: cgb:cg0040 putative secreted protein. (408 aa)
Mflv_3643PFAM: RNA-binding S4 domain protein; KEGG: mmc:Mmcs_3096 RNA-binding S4. (80 aa)
Mflv_3667KEGG: mmc:Mmcs_2447 hypothetical protein. (64 aa)
Mflv_3668PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mmc:Mmcs_2446 ABC transporter related. (542 aa)
Mflv_3671KEGG: mbo:Mb3795 hypothetical protein. (93 aa)
Mflv_3672PFAM: protein of unknown function DUF59; KEGG: mmc:Mmcs_2441 protein of unknown function DUF59. (119 aa)
Mflv_3673TIGRFAM: SUF system FeS assembly protein, NifU family; PFAM: nitrogen-fixing NifU domain protein; KEGG: mmc:Mmcs_2440 SUF system FeS assembly protein. (155 aa)
Mflv_3674Cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. (419 aa)
Mflv_3675KEGG: nfa:nfa35580 putative ABC transporter ATP-binding protein; TIGRFAM: FeS assembly ATPase SufC; PFAM: ABC transporter related; SMART: AAA ATPase. (256 aa)
Mflv_3676Iron-regulated ABC transporter permease protein SufD; TIGRFAM: FeS assembly protein SufD; PFAM: SufBD protein; KEGG: mmc:Mmcs_2437 FeS assembly protein SufD. (399 aa)
Mflv_3677Iron-regulated ABC transporter membrane component SufB; TIGRFAM: FeS assembly protein SufB; PFAM: SufBD protein; KEGG: mmc:Mmcs_2436 FeS assembly protein SufB. (479 aa)
Mflv_3678PFAM: regulatory protein, ArsR; Helix-turn-helix, type 11 domain protein; KEGG: mva:Mvan_2732 putative transcriptional regulator. (245 aa)
Mflv_3679KEGG: mmc:Mmcs_2434 hypothetical protein. (551 aa)
Mflv_3680PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mva:Mvan_2730 ABC transporter-related protein. (319 aa)
Mflv_3681TIGRFAM: ABC drug efflux pump, inner membrane subunit, DrrB family; PFAM: ABC-2 type transporter; KEGG: mmc:Mmcs_2432 ABC transporter, DrrB efflux protein. (259 aa)
Mflv_3812(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (790 aa)
Mflv_3879PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: mmc:Mmcs_2898 anti-sigma-factor antagonist. (155 aa)
Mflv_3880KEGG: msm:MSMEG_1076 hypothetical protein. (92 aa)
Mflv_3881PFAM: CsbD family protein; KEGG: nfa:nfa43340 hypothetical protein; Belongs to the UPF0337 (CsbD) family. (79 aa)
Mflv_3882PFAM: periplasmic binding protein; KEGG: sco:SCO0996 putative lipoprotein. (326 aa)
Mflv_3883PFAM: transport system permease protein; KEGG: sco:SCO0997 Fe uptake system integral membrane protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (353 aa)
Mflv_3884PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sco:SCO0998 Fe uptake system permease. (267 aa)
Mflv_3885KEGG: mmc:Mmcs_1464 hypothetical protein. (225 aa)
Mflv_4126Amino acid/polyamine/organocation transporter, APC superfamily; PFAM: amino acid permease-associated region; KEGG: mmc:Mmcs_1999 amino acid permease-associated region; TC 2.A.3. (502 aa)
Mflv_4127PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mmc:Mmcs_1998 ABC transporter related. (241 aa)
Mflv_4128PFAM: protein of unknown function DUF214; KEGG: mmc:Mmcs_1997 protein of unknown function DUF214. (189 aa)
Mflv_4129PFAM: protein of unknown function DUF214; KEGG: mmc:Mmcs_1996 protein of unknown function DUF214. (383 aa)
ppkPolyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP); Belongs to the polyphosphate kinase 1 (PPK1) family. (729 aa)
Mflv_4278PFAM: periplasmic binding protein; KEGG: mmc:Mmcs_1851 periplasmic binding protein. (405 aa)
Mflv_4700KEGG: mbo:Mb3260c hypothetical protein. (182 aa)
Mflv_4701PFAM: protein of unknown function DUF344; KEGG: mbo:Mb3261c possible transcriptional regulatory protein PvdS (probable RNA polymerase sigma factor). (285 aa)
Mflv_4702TIGRFAM: choline/carnitine/betaine transporter; PFAM: BCCT transporter; KEGG: mmc:Mmcs_1356 choline/carnitine/betaine transport; Belongs to the BCCT transporter (TC 2.A.15) family. (583 aa)
Mflv_4703Diacylglycerol O-acyltransferase; PFAM: protein of unknown function UPF0089; KEGG: mmc:Mmcs_1355 protein of unknown function UPF0089; Belongs to the long-chain O-acyltransferase family. (469 aa)
Mflv_4704KEGG: mmc:Mmcs_1354 conserved hypothetical alanine arginine proline rich protein. (173 aa)
Mflv_4944Hypothetical protein. (204 aa)
Mflv_4945KEGG: mbo:Mb3469c conserved hypothetical alanine and proline rich protein. (463 aa)
Mflv_4946KEGG: mmc:Mmcs_1135 hypothetical protein. (101 aa)
Mflv_4948KEGG: mmc:Mmcs_1132 hypothetical protein. (153 aa)
Mflv_5091PFAM: Collagen triple helix repeat. (766 aa)
Your Current Organism:
Mycolicibacterium gilvum
NCBI taxonomy Id: 350054
Other names: M. gilvum PYR-GCK, Mycobacterium flavescens ATCC 700033, Mycobacterium flavescens PYR-GCK, Mycobacterium gilvum PYR-GCK, Mycolicibacterium gilvum PYR-GCK
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