STRINGSTRING
Mflv_2529 Mflv_2529 Mflv_4860 Mflv_4860 Mflv_4389 Mflv_4389 dxr dxr ispG ispG Mflv_4063 Mflv_4063 Mflv_3819 Mflv_3819 Mflv_3083 Mflv_3083 Mflv_2528 Mflv_2528 ispH ispH ispE ispE Mflv_1907 Mflv_1907 Mflv_1797 Mflv_1797 ispF ispF Mflv_0667 Mflv_0667 Mflv_0643 Mflv_0643 Mflv_0569 Mflv_0569 Mflv_0428 Mflv_0428
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Mflv_25292-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; KEGG: ace:Acel_1533 4-diphosphocytidyl-2C-methyl-D-erythritol synthase. (237 aa)
Mflv_4860PFAM: aldehyde dehydrogenase; KEGG: mmc:Mmcs_1220 betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (491 aa)
Mflv_4389PFAM: aldehyde dehydrogenase; KEGG: rha:RHA1_ro00395 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (482 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (387 aa)
ispG4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (391 aa)
Mflv_4063PFAM: aldehyde dehydrogenase; KEGG: mmc:Mmcs_2059 betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (454 aa)
Mflv_3819PFAM: aldehyde dehydrogenase; KEGG: mmc:Mmcs_2273 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (477 aa)
Mflv_3083PFAM: aldehyde dehydrogenase; KEGG: mmc:Mmcs_2462 betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (499 aa)
Mflv_2528PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; KEGG: nfa:nfa4360 putative 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase. (223 aa)
ispH4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (333 aa)
ispE4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (322 aa)
Mflv_1907PFAM: aldehyde dehydrogenase; KEGG: mpa:MAP2782 hypothetical protein. (485 aa)
Mflv_1797PFAM: aldehyde dehydrogenase; KEGG: mmc:Mmcs_4395 aldehyde dehydrogenase. (474 aa)
ispF2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (160 aa)
Mflv_0667PFAM: aldehyde dehydrogenase; KEGG: mkm:Mkms_1663 aldehyde dehydrogenase (NAD(+)). (486 aa)
Mflv_0643PFAM: aldehyde dehydrogenase; KEGG: mkm:Mkms_5636 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (477 aa)
Mflv_0569PFAM: aldehyde dehydrogenase; KEGG: mkm:Mkms_1663 aldehyde dehydrogenase (NAD(+)); Belongs to the aldehyde dehydrogenase family. (486 aa)
Mflv_0428PFAM: aldehyde dehydrogenase; KEGG: mva:Mvan_0240 betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (492 aa)
Your Current Organism:
Mycolicibacterium gilvum
NCBI taxonomy Id: 350054
Other names: M. gilvum PYR-GCK, Mycobacterium flavescens ATCC 700033, Mycobacterium flavescens PYR-GCK, Mycobacterium gilvum PYR-GCK, Mycolicibacterium gilvum PYR-GCK
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