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Mflv_2485 Mflv_2485 atpC atpC atpD atpD atpG atpG atpA atpA atpFH atpFH atpF atpF atpE atpE atpB atpB Mflv_2258 Mflv_2258 Mflv_2215 Mflv_2215 tatB tatB Mflv_2100 Mflv_2100 Mflv_2099 Mflv_2099 Mflv_1952 Mflv_1952 Mflv_1937 Mflv_1937 Mflv_1891 Mflv_1891 Mflv_1745 Mflv_1745 Mflv_1661 Mflv_1661 Mflv_1555 Mflv_1555 Mflv_1554 Mflv_1554 Mflv_1456 Mflv_1456 Mflv_1232 Mflv_1232 Mflv_1207 Mflv_1207 Mflv_1083 Mflv_1083 Mflv_1013 Mflv_1013 Mflv_0723 Mflv_0723 Mflv_0713 Mflv_0713 Mflv_0712 Mflv_0712 Mflv_0654 Mflv_0654 Mflv_3582 Mflv_3582 Mflv_0119 Mflv_0119 Mflv_0012 Mflv_0012 Mflv_0011 Mflv_0011 Mflv_4493 Mflv_4493 Mflv_4539 Mflv_4539 Mflv_4540 Mflv_4540 Mflv_4844 Mflv_4844 Mflv_0653 Mflv_0653 Mflv_3604 Mflv_3604 Mflv_3681 Mflv_3681 Mflv_3778 Mflv_3778 Mflv_3854 Mflv_3854 Mflv_3970 Mflv_3970 Mflv_3971 Mflv_3971 Mflv_4055 Mflv_4055 Mflv_4057 Mflv_4057 Mflv_4058 Mflv_4058 Mflv_4272 Mflv_4272 Mflv_4485 Mflv_4485 Mflv_4486 Mflv_4486 Mflv_3503 Mflv_3503 Mflv_4487 Mflv_4487 Mflv_3388 Mflv_3388 Mflv_3387 Mflv_3387 Mflv_3361 Mflv_3361 Mflv_3166 Mflv_3166 potA potA Mflv_3111 Mflv_3111 tatC tatC tatA tatA fbpC fbpC Mflv_2761 Mflv_2761 cysA cysA Mflv_2507 Mflv_2507 Mflv_2506 Mflv_2506
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
Mflv_2485PFAM: Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; KEGG: mmc:Mmcs_3690 respiratory-chain NADH dehydrogenase domain, 51 kDa subunit. (430 aa)
atpCATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (121 aa)
atpDATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (476 aa)
atpGATP synthase F1 subcomplex gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (309 aa)
atpAATP synthase F1 subcomplex alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (548 aa)
atpFHATP synthase F1 subcomplex delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity). (445 aa)
atpFH+-transporting two-sector ATPase, B/B' subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (171 aa)
atpEATP synthase F0 subcomplex C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (81 aa)
atpBATP synthase F0 subcomplex A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (259 aa)
Mflv_2258PFAM: extracellular solute-binding protein, family 5; KEGG: mmc:Mmcs_3931 extracellular solute-binding protein, family 5. (558 aa)
Mflv_2215PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: mmc:Mmcs_3976 substrate-binding region of ABC-type glycine betaine transport system. (241 aa)
tatBTwin-arginine translocation protein, TatB subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. (141 aa)
Mflv_2100PFAM: protein of unknown function DUF140; KEGG: mva:Mvan_4605 protein of unknown function DUF140. (284 aa)
Mflv_2099PFAM: protein of unknown function DUF140; KEGG: mmc:Mmcs_1522 protein of unknown function DUF140. (255 aa)
Mflv_1952PFAM: iron permease FTR1; KEGG: rha:RHA1_ro05775 possible membrane protein. (304 aa)
Mflv_1937PFAM: ABC-2 type transporter; KEGG: mmc:Mmcs_4259 ABC-2 type transporter. (284 aa)
Mflv_1891KEGG: mmc:Mmcs_4296 hypothetical protein. (217 aa)
Mflv_1745PFAM: Ion transport protein; Ion transport 2 domain protein,; KEGG: mkm:Mkms_4534 ion transport 2 domain protein. (252 aa)
Mflv_1661Phosphate ABC transporter substrate-binding protein, PhoT family; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family. (376 aa)
Mflv_1555PFAM: protein of unknown function DUF140; KEGG: mmc:Mmcs_4618 protein of unknown function DUF140. (280 aa)
Mflv_1554PFAM: protein of unknown function DUF140; KEGG: mmc:Mmcs_4619 protein of unknown function DUF140. (237 aa)
Mflv_1456PFAM: ABC-3 protein; KEGG: mva:Mvan_5318 ABC-3 protein. (291 aa)
Mflv_1232L-cystine transport system substrate-binding protein; KEGG: mva:Mvan_5576 polar amino acid ABC transporter, inner membrane subunit; TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; extracellular solute-binding protein, family 3; SMART: ionotropic glutamate receptor; TC 3.A.1.3.-; TC 3.A.1.3.-. (503 aa)
Mflv_1207PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: mva:Mvan_5601 substrate-binding region of ABC-type glycine betaine transport system. (316 aa)
Mflv_1083PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: mva:Mvan_5739 ABC transporter-related protein. (347 aa)
Mflv_1013KEGG: mva:Mvan_5823 conserved hypothetical protein. (225 aa)
Mflv_0723PFAM: Substrate-binding region of ABC-type glycine betaine transport system; SMART: extracellular solute-binding protein, family 3; KEGG: mva:Mvan_0122 substrate-binding region of ABC-type glycine betaine transport system. (345 aa)
Mflv_0713PFAM: protein of unknown function DUF140; KEGG: mva:Mvan_0132 protein of unknown function DUF140. (265 aa)
Mflv_0712PFAM: protein of unknown function DUF140; KEGG: mva:Mvan_0133 protein of unknown function DUF140. (290 aa)
Mflv_0654PFAM: protein of unknown function DUF140; KEGG: mva:Mvan_0498 protein of unknown function DUF140. (269 aa)
Mflv_3582TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mva:Mvan_2833 polar amino acid ABC transporter, inner membrane subunit; TC 3.A.1.3.-. (310 aa)
Mflv_0119PFAM: extracellular solute-binding protein, family 5; KEGG: cdi:DIP2128 putative substrate-binding transport protein. (532 aa)
Mflv_0012PFAM: protein of unknown function DUF140; KEGG: mva:Mvan_0957 protein of unknown function DUF140. (312 aa)
Mflv_0011PFAM: protein of unknown function DUF140; KEGG: mva:Mvan_0958 protein of unknown function DUF140. (285 aa)
Mflv_4493KEGG: mmc:Mmcs_1565 proton-translocating NADH-quinone oxidoreductase, chain M; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I). (511 aa)
Mflv_4539PFAM: protein of unknown function DUF140; KEGG: mmc:Mmcs_0274 protein of unknown function DUF140. (282 aa)
Mflv_4540PFAM: protein of unknown function DUF140; KEGG: mpa:MAP0757 putative ABC transport system permease protein. (270 aa)
Mflv_4844PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: mmc:Mmcs_1230 succinate dehydrogenase, cytochrome b subunit. (142 aa)
Mflv_0653PFAM: protein of unknown function DUF140; KEGG: mva:Mvan_0499 protein of unknown function DUF140. (285 aa)
Mflv_3604PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: nfa:nfa24620 putative ABC transporter ATP-binding protein. (264 aa)
Mflv_3681TIGRFAM: ABC drug efflux pump, inner membrane subunit, DrrB family; PFAM: ABC-2 type transporter; KEGG: mmc:Mmcs_2432 ABC transporter, DrrB efflux protein. (259 aa)
Mflv_3778Carbohydrate ABC transporter ATP-binding protein, CUT1 family; PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: mmc:Mmcs_2417 ABC transporter related; TC 3.A.1.1.-. (356 aa)
Mflv_3854Carbohydrate ABC transporter ATP-binding protein, CUT1 family; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rha:RHA1_ro05991 ABC sugar transporter, ATP-binding component; TC 3.A.1.1.-; Belongs to the ABC transporter superfamily. (409 aa)
Mflv_3970TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mmc:Mmcs_2154 amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine; TC 3.A.1.3.-. (226 aa)
Mflv_3971TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mva:Mvan_2425 polar amino acid ABC transporter, inner membrane subunit; TC 3.A.1.3.-. (291 aa)
Mflv_4055Cobalt ABC transporter, ATPase subunit; KEGG: mmc:Mmcs_2066 ABC transporter related; TIGRFAM: cobalt ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase. (250 aa)
Mflv_4057KEGG: mmc:Mmcs_2064 hypothetical protein. (123 aa)
Mflv_4058PFAM: cobalamin (vitamin B12) biosynthesis CbiM protein; KEGG: mmc:Mmcs_2063 cobalamin (vitamin B12) biosynthesis CbiM protein. (235 aa)
Mflv_4272PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mva:Mvan_2087 ABC transporter-related protein. (280 aa)
Mflv_4485TIGRFAM: NADH-quinone oxidoreductase, E subunit; PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit; KEGG: mmc:Mmcs_1576 NADH dehydrogenase (ubiquinone), 24 kDa subunit. (287 aa)
Mflv_4486NADH-quinone oxidoreductase, F subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (438 aa)
Mflv_3503KEGG: mmc:Mmcs_2945 hypothetical protein. (313 aa)
Mflv_4487NADH dehydrogenase subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (799 aa)
Mflv_3388PFAM: ABC-2 type transporter; KEGG: mmc:Mmcs_2830 ABC transporter, DrrB efflux protein. (282 aa)
Mflv_3387TIGRFAM: ABC drug efflux pump, inner membrane subunit, DrrB family; PFAM: ABC-2 type transporter; KEGG: mva:Mvan_3120 ABC drug efflux pump, inner membrane subunit, DrrB family. (281 aa)
Mflv_3361PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: rha:RHA1_ro08545 Fe(3+)-transporting ATPase protein SfuC; Belongs to the ABC transporter superfamily. (364 aa)
Mflv_3166PFAM: ABC-3 protein; KEGG: rha:RHA1_ro07269 possible ABC Mn(2+)/Zn(2+) transporter, permease component. (314 aa)
potASpermidine/putrescine ABC transporter ATPase subunit; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. (423 aa)
Mflv_3111PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: mmc:Mmcs_2495 substrate-binding region of ABC-type glycine betaine transport system. (324 aa)
tatCSec-independent protein translocase, TatC subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. (314 aa)
tatATwin-arginine translocation protein, TatA/E family subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (84 aa)
fbpCABC transporter related protein; Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system. (359 aa)
Mflv_2761PFAM: extracellular solute-binding protein, family 5; KEGG: mmc:Mmcs_3391 extracellular solute-binding protein, family 5. (515 aa)
cysASulfate ABC transporter, ATPase subunit; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. (344 aa)
Mflv_2507PFAM: protein of unknown function DUF140; KEGG: mmc:Mmcs_3672 protein of unknown function DUF140. (285 aa)
Mflv_2506PFAM: protein of unknown function DUF140; KEGG: mmc:Mmcs_3673 protein of unknown function DUF140. (269 aa)
Your Current Organism:
Mycolicibacterium gilvum
NCBI taxonomy Id: 350054
Other names: M. gilvum PYR-GCK, Mycobacterium flavescens ATCC 700033, Mycobacterium flavescens PYR-GCK, Mycobacterium gilvum PYR-GCK, Mycolicibacterium gilvum PYR-GCK
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