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Mflv_0176 Mflv_0176 Mflv_0279 Mflv_0279 ilvD ilvD leuA leuA Mflv_1304 Mflv_1304 asd asd Mflv_1545 Mflv_1545 Mflv_1726 Mflv_1726 Mflv_1729 Mflv_1729 Mflv_2940 Mflv_2940 Mflv_3455 Mflv_3455 argD argD argB argB argJ argJ argC argC Mflv_3665 Mflv_3665 Mflv_3990 Mflv_3990 leuD leuD leuC leuC leuB leuB ilvC ilvC Mflv_4238 Mflv_4238 Mflv_4239 Mflv_4239 Mflv_4833 Mflv_4833 ilvD-2 ilvD-2
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Mflv_0176PFAM: GCN5-related N-acetyltransferase; KEGG: mva:Mvan_0731 GCN5-related N-acetyltransferase. (295 aa)
Mflv_0279L-aspartate aminotransferase apoenzyme; PFAM: aminotransferase, class I and II; KEGG: mva:Mvan_0618 aminotransferase, class I and II. (422 aa)
ilvDKEGG: mkm:Mkms_0155 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (589 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (606 aa)
Mflv_1304KEGG: mva:Mvan_5504 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. (440 aa)
asdAspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (347 aa)
Mflv_1545PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: mbo:Mb3539c probable acetohydroxyacid synthase IlvX (acetolactate synthase). (531 aa)
Mflv_1726PFAM: Citrate synthase; KEGG: mva:Mvan_5025 citrate (Si)-synthase; Belongs to the citrate synthase family. (373 aa)
Mflv_1729KEGG: mmc:Mmcs_4456 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. (434 aa)
Mflv_2940KEGG: mmc:Mmcs_3308 branched-chain amino acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase, class IV. (367 aa)
Mflv_3455KEGG: mmc:Mmcs_1209 isocitrate dehydrogenase, NADP-dependent; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate dehydrogenase NADP-dependent, monomeric type; Belongs to the monomeric-type IDH family. (749 aa)
argDAminotransferase; TIGRFAM: acetylornithine and succinylornithine aminotransferases; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class-III; KEGG: mmc:Mmcs_2969 acetylornithine and succinylornithine aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (395 aa)
argBN-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (290 aa)
argJGlutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (398 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (349 aa)
Mflv_3665Aconitase; TIGRFAM: aconitate hydratase 1; PFAM: aconitate hydratase domain protein; KEGG: mmc:Mmcs_2449 aconitate hydratase 1. (941 aa)
Mflv_3990N-acetylglutamate synthase; PFAM: GCN5-related N-acetyltransferase; KEGG: mva:Mvan_2394 GCN5-related N-acetyltransferase; Belongs to the acetyltransferase family. (161 aa)
leuD3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (197 aa)
leuC3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (481 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. (336 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (337 aa)
Mflv_4238TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: mmc:Mmcs_1907 acetolactate synthase, small subunit. (166 aa)
Mflv_4239TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: mmc:Mmcs_1906 acetolactate synthase, large subunit, biosynthetic type. (620 aa)
Mflv_4833Diaminobutyrate aminotransferase apoenzyme; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (433 aa)
ilvD-2KEGG: sco:SCO3345 dihydroxy acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (613 aa)
Your Current Organism:
Mycolicibacterium gilvum
NCBI taxonomy Id: 350054
Other names: M. gilvum PYR-GCK, Mycobacterium flavescens ATCC 700033, Mycobacterium flavescens PYR-GCK, Mycobacterium gilvum PYR-GCK, Mycolicibacterium gilvum PYR-GCK
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