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Mvan_4776 Mvan_4776 deoC deoC Mvan_1121 Mvan_1121 Mvan_1142 Mvan_1142 Mvan_1144 Mvan_1144 Mvan_1155 Mvan_1155 Mvan_1526 Mvan_1526 Mvan_1590 Mvan_1590 Mvan_1805 Mvan_1805 rnhB rnhB pnp pnp Mvan_2437 Mvan_2437 dut dut Mvan_2559 Mvan_2559 Mvan_2820 Mvan_2820 Mvan_3440 Mvan_3440 Mvan_3815 Mvan_3815 Mvan_3829 Mvan_3829 Mvan_4286 Mvan_4286 rph rph deaD deaD xseA xseA xseB xseB Mvan_4903 Mvan_4903 rnhA rnhA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Mvan_4776PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: mmc:Mmcs_4244 MazG nucleotide pyrophosphohydrolase. (327 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (225 aa)
Mvan_1121Hypothetical protein. (332 aa)
Mvan_1142PFAM: ribonuclease H; KEGG: nfa:nfa39810 hypothetical protein. (307 aa)
Mvan_1144Transcriptional modulator of MazE/toxin, MazF; Toxic component of a type II toxin-antitoxin (TA) system. (115 aa)
Mvan_1155KEGG: sco:SCO0324 secreted protein. (776 aa)
Mvan_1526PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: mmc:Mmcs_1178 inosine/uridine-preferring nucleoside hydrolase. (349 aa)
Mvan_1590PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: mmc:Mmcs_1231 cytidine deaminase, homotetrameric. (140 aa)
Mvan_1805PFAM: NUDIX hydrolase; KEGG: mmc:Mmcs_1407 NUDIX hydrolase. (308 aa)
rnhBRNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (249 aa)
pnpPolyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (754 aa)
Mvan_2437PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: mmc:Mmcs_2165 DEAD/DEAH box helicase-like protein. (443 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (154 aa)
Mvan_2559PFAM: histidine triad (HIT) protein; KEGG: mmc:Mmcs_2243 histidine triad (HIT) protein. (182 aa)
Mvan_2820PFAM: TM2 domain containing protein+B7201; KEGG: mmc:Mmcs_3046 TM2 domain containing protein. (143 aa)
Mvan_3440PFAM: helicase domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; DSH domain protein; SMART: DEAD-like helicases-like; KEGG: mmc:Mmcs_2476 DEAD/DEAH box helicase-like protein. (929 aa)
Mvan_3815KEGG: mmc:Mmcs_3443 deoxyguanosinetriphosphate triphosphohydrolase; TIGRFAM: putative deoxyguanosinetriphosphate triphosphohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; Belongs to the dGTPase family. Type 2 subfamily. (424 aa)
Mvan_3829KEGG: mbo:Mb2386c hypothetical protein. (105 aa)
Mvan_4286Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (183 aa)
rphRNAse PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (260 aa)
deaDATP-dependent RNA helicase CsdA; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. (564 aa)
xseAExodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (410 aa)
xseBExodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (70 aa)
Mvan_4903Hypothetical protein. (216 aa)
rnhARibonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (154 aa)
Your Current Organism:
Mycolicibacterium vanbaalenii
NCBI taxonomy Id: 350058
Other names: M. vanbaalenii PYR-1, Mycobacterium sp. PYR-1, Mycobacterium vanbaalenii DSM 7251, Mycobacterium vanbaalenii PYR-1, Mycolicibacterium vanbaalenii DSM 7251, Mycolicibacterium vanbaalenii PYR-1
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