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glyA glyA Mvan_3146 Mvan_3146 Mvan_0618 Mvan_0618 metZ metZ hemL hemL Mvan_1179 Mvan_1179 Mvan_1287 Mvan_1287 Mvan_1355 Mvan_1355 Mvan_1554 Mvan_1554 Mvan_5803 Mvan_5803 Mvan_5776 Mvan_5776 Mvan_5616 Mvan_5616 Mvan_1652 Mvan_1652 Mvan_1823 Mvan_1823 Mvan_1858 Mvan_1858 Mvan_2084 Mvan_2084 Mvan_2105 Mvan_2105 Mvan_2142 Mvan_2142 Mvan_2581 Mvan_2581 Mvan_2736 Mvan_2736 bioA bioA Mvan_2789 Mvan_2789 Mvan_4670 Mvan_4670 serC serC Mvan_5070 Mvan_5070 gcvP gcvP Mvan_2918 Mvan_2918 hisC hisC argD argD Mvan_4528 Mvan_4528 Mvan_4610 Mvan_4610 pat pat Mvan_5565 Mvan_5565 Mvan_5535 Mvan_5535 egtE egtE Mvan_1570 Mvan_1570 Mvan_5273 Mvan_5273
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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from curated databases
experimentally determined
Predicted Interactions
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glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (487 aa)
Mvan_3146PFAM: aminotransferase class-III; KEGG: gsu:GSU0151 acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (408 aa)
Mvan_0618L-aspartate aminotransferase apoenzyme; PFAM: aminotransferase, class I and II; KEGG: mbo:Mb0344c probable aspartate aminotransferase AspC (transaminase A) (ASPAT). (426 aa)
metZO-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (411 aa)
hemLTIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase, class I and II; aminotransferase class-III; KEGG: mmc:Mmcs_0690 glutamate-1-semialdehyde-2,1-aminomutase. (432 aa)
Mvan_1179L-threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: dde:Dde_1657 threonine aldolase. (343 aa)
Mvan_1287Aminotransferase; TIGRFAM: ornithine aminotransferase; PFAM: aminotransferase class-III; KEGG: mmc:Mmcs_0992 ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (403 aa)
Mvan_1355PFAM: aminotransferase, class I and II; KEGG: mpa:MAP4211 hypothetical protein. (343 aa)
Mvan_1554KEGG: mmc:Mmcs_1208 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase. (447 aa)
Mvan_5803PFAM: aminotransferase class-III; KEGG: bur:Bcep18194_B0665 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (433 aa)
Mvan_5776PFAM: aminotransferase class-III; KEGG: mmc:Mmcs_0347 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (484 aa)
Mvan_5616TIGRFAM: cysteine desulfurase family protein; PFAM: aminotransferase, class V; KEGG: mmc:Mmcs_4989 cysteine desulphurase related. (398 aa)
Mvan_1652L-lysine 6-transaminase precursor; PFAM: aminotransferase class-III; KEGG: mmc:Mmcs_1272 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (451 aa)
Mvan_1823PFAM: aminotransferase class-III; KEGG: mmc:Mmcs_0347 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (464 aa)
Mvan_1858TIGRFAM: 4-aminobutyrate aminotransferase; PFAM: aminotransferase class-III; KEGG: tfu:Tfu_0690 bacterial 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (450 aa)
Mvan_2084Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II; KEGG: mmc:Mmcs_1854 transcriptional regulator, GntR family. (504 aa)
Mvan_2105PFAM: aminotransferase, class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: mmc:Mmcs_1875 aminotransferase, class V. (397 aa)
Mvan_2142PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; KEGG: mmc:Mmcs_1928 Cys/Met metabolism pyridoxal-phosphate-dependent enzymes. (369 aa)
Mvan_2581TIGRFAM: 4-aminobutyrate aminotransferase; PFAM: aminotransferase class-III; KEGG: mmc:Mmcs_2274 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (446 aa)
Mvan_2736Cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. (415 aa)
bioAAdenosylmethionine-8-amino-7-oxononanoate aminotransferase apoenzyme; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (433 aa)
Mvan_27898-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (380 aa)
Mvan_4670Cystathionine gamma-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: mmc:Mmcs_4146 cystathionine gamma-synthase. (393 aa)
serCAminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (371 aa)
Mvan_5070Succinyldiaminopimelate aminotransferase apoenzyme; PFAM: aminotransferase, class I and II; KEGG: mmc:Mmcs_4497 aminotransferase, class I and II. (391 aa)
gcvPGlycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (950 aa)
Mvan_2918PFAM: aminotransferase class-III; KEGG: sme:SMc02413 putative aminotransferase protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (435 aa)
hisCTIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase, class I and II; KEGG: mpa:MAP1294 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (373 aa)
argDAminotransferase; TIGRFAM: acetylornithine and succinylornithine aminotransferases; PFAM: aminotransferase class-III; KEGG: mmc:Mmcs_2969 acetylornithine and succinylornithine aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (390 aa)
Mvan_4528Succinyldiaminopimelate aminotransferase apoenzyme; PFAM: aminotransferase, class I and II; KEGG: mbo:Mb1211 probable aminotransferase. (359 aa)
Mvan_4610Aminotransferase; PFAM: aminoglycoside phosphotransferase; aminotransferase class-III; KEGG: mmc:Mmcs_4091 aminotransferase class-III. (977 aa)
patAminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (351 aa)
Mvan_5565PFAM: aminotransferase class-III; KEGG: mmc:Mmcs_0198 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (426 aa)
Mvan_5535Putative transcriptional regulator, GntR family; PFAM: aminotransferase, class I and II; KEGG: mmc:Mmcs_4910 aminotransferase, class I and II. (433 aa)
egtEAminotransferase, class V; Probably catalyzes the conversion of hercynylcysteine sulfoxide to ergothioneine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily. (359 aa)
Mvan_1570PFAM: aminotransferase class-III; KEGG: mmc:Mmcs_1218 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (461 aa)
Mvan_5273Diaminobutyrate aminotransferase apoenzyme; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (429 aa)
Your Current Organism:
Mycolicibacterium vanbaalenii
NCBI taxonomy Id: 350058
Other names: M. vanbaalenii PYR-1, Mycobacterium sp. PYR-1, Mycobacterium vanbaalenii DSM 7251, Mycobacterium vanbaalenii PYR-1, Mycolicibacterium vanbaalenii DSM 7251, Mycolicibacterium vanbaalenii PYR-1
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