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Mvan_0044 Mvan_0044 Mvan_0443 Mvan_0443 Mvan_0463 Mvan_0463 Mvan_0464 Mvan_0464 Mvan_0466 Mvan_0466 Mvan_0467 Mvan_0467 Mvan_0470 Mvan_0470 Mvan_0472 Mvan_0472 Mvan_0483 Mvan_0483 Mvan_0486 Mvan_0486 Mvan_0487 Mvan_0487 Mvan_0488 Mvan_0488 Mvan_0495 Mvan_0495 nidB3 nidB3 Mvan_0538 Mvan_0538 Mvan_0544 Mvan_0544 Mvan_0545 Mvan_0545 Mvan_0560 Mvan_0560 Mvan_0561 Mvan_0561 Mvan_0562 Mvan_0562 Mvan_0563 Mvan_0563 Mvan_0592 Mvan_0592 Mvan_0593 Mvan_0593 Mvan_0595 Mvan_0595 Mvan_0596 Mvan_0596 Mvan_0597 Mvan_0597 Mvan_0669 Mvan_0669 Mvan_1216 Mvan_1216 Mvan_1290 Mvan_1290 Mvan_1327 Mvan_1327 Mvan_1329 Mvan_1329 Mvan_2243 Mvan_2243 Mvan_2891 Mvan_2891 Mvan_3073 Mvan_3073 Mvan_3156 Mvan_3156 Mvan_3396 Mvan_3396 Mvan_4167 Mvan_4167 Mvan_4181 Mvan_4181 Mvan_4185 Mvan_4185 mhpB mhpB mhpA mhpA Mvan_4246 Mvan_4246 Mvan_4316 Mvan_4316 Mvan_4391 Mvan_4391 Mvan_4392 Mvan_4392 Mvan_4393 Mvan_4393 Mvan_4405 Mvan_4405 Mvan_4406 Mvan_4406 Mvan_4409 Mvan_4409 Mvan_4412 Mvan_4412 Mvan_4414 Mvan_4414 Mvan_4415 Mvan_4415 Mvan_4821 Mvan_4821 Mvan_4906 Mvan_4906 Mvan_4934 Mvan_4934 Mvan_4961 Mvan_4961 Mvan_5154 Mvan_5154 Mvan_5164 Mvan_5164 Mvan_5234 Mvan_5234 Mvan_5235 Mvan_5235 Mvan_5236 Mvan_5236 Mvan_5306 Mvan_5306 Mvan_5307 Mvan_5307 Mvan_5450 Mvan_5450 Mvan_5476 Mvan_5476
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Mvan_0044PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR; KEGG: mmc:Mmcs_5285 short-chain dehydrogenase/reductase SDR. (230 aa)
Mvan_0443PFAM: iron-containing alcohol dehydrogenase; aldehyde dehydrogenase; KEGG: aba:Acid345_0379 iron-containing alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (858 aa)
Mvan_0463PFAM: ring hydroxylating dioxygenase, alpha subunit; Rieske [2Fe-2S] domain protein; KEGG: mmc:Mmcs_1622 ring hydroxylating dioxygenase, alpha subunit. (484 aa)
Mvan_0464PFAM: aromatic-ring-hydroxylating dioxygenase, beta subunit; KEGG: mmc:Mmcs_1623 aromatic-ring-hydroxylating dioxygenase, beta subunit. (198 aa)
Mvan_0466Phthalate 3,4-dihydrodiol dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mmc:Mmcs_1624 short-chain dehydrogenase/reductase SDR. (267 aa)
Mvan_0467Phthalate 3,4-dioxygenase, ferredoxin reductase subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mmc:Mmcs_1625 FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (468 aa)
Mvan_0470PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: mmc:Mmcs_1630 glyoxalase/bleomycin resistance protein/dioxygenase. (296 aa)
Mvan_0472PFAM: dihydrodipicolinate synthetase; KEGG: mmc:Mmcs_1632 dihydrodipicolinate synthetase; Belongs to the DapA family. (341 aa)
Mvan_0483PFAM: aromatic-ring-hydroxylating dioxygenase, beta subunit; KEGG: mmc:Mmcs_1641 aromatic-ring-hydroxylating dioxygenase, beta subunit. (169 aa)
Mvan_0486PFAM: aldehyde dehydrogenase; KEGG: mmc:Mmcs_1637 aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family. (486 aa)
Mvan_0487PFAM: aromatic-ring-hydroxylating dioxygenase, beta subunit; KEGG: mmc:Mmcs_1641 aromatic-ring-hydroxylating dioxygenase, beta subunit. (169 aa)
Mvan_0488PFAM: ring hydroxylating dioxygenase, alpha subunit; Rieske [2Fe-2S] domain protein; KEGG: mmc:Mmcs_1642 ring hydroxylating dioxygenase, alpha subunit. (455 aa)
Mvan_0495PFAM: intradiol ring-cleavage dioxygenase; KEGG: mmc:Mmcs_1649 intradiol ring-cleavage dioxygenase. (172 aa)
nidB3PFAM: aromatic-ring-hydroxylating dioxygenase, beta subunit; KEGG: mmc:Mmcs_1667 aromatic-ring-hydroxylating dioxygenase, beta subunit. (180 aa)
Mvan_0538PFAM: alpha/beta hydrolase fold; KEGG: mmc:Mmcs_1679 alpha/beta hydrolase fold. (299 aa)
Mvan_0544PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mmc:Mmcs_1685 short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (301 aa)
Mvan_0545PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: mmc:Mmcs_1630 glyoxalase/bleomycin resistance protein/dioxygenase. (296 aa)
Mvan_0560TIGRFAM: protocatechuate 3,4-dioxygenase, beta subunit; PFAM: intradiol ring-cleavage dioxygenase; KEGG: mmc:Mmcs_1698 protocatechuate 3,4-dioxygenase, beta subunit. (265 aa)
Mvan_0561TIGRFAM: protocatechuate 3,4-dioxygenase, alpha subunit; PFAM: intradiol ring-cleavage dioxygenase; KEGG: mmc:Mmcs_1699 protocatechuate 3,4-dioxygenase, alpha subunit. (189 aa)
Mvan_05623-carboxy-cis,cis-muconate cycloisomerase; PFAM: fumarate lyase; KEGG: mmc:Mmcs_1700 fumarate lyase. (401 aa)
Mvan_0563TIGRFAM: 4-carboxymuconolactone decarboxylase; PFAM: alpha/beta hydrolase fold; Carboxymuconolactone decarboxylase; KEGG: mmc:Mmcs_1701 4-carboxymuconolactone decarboxylase. (393 aa)
Mvan_0592PFAM: alpha/beta hydrolase fold; KEGG: nfa:nfa4730 putative hydrolase. (288 aa)
Mvan_0593PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase; KEGG: mxa:MXAN_7320 FAD-binding monooxygenase, PheA/TfdB family. (520 aa)
Mvan_0595PFAM: Hydratase/decarboxylase; KEGG: mta:Moth_1777 4-oxalocrotonate decarboxylase. (262 aa)
Mvan_0596PFAM: Semialdehyde dehydrogenase, NAD - binding; KEGG: bur:Bcep18194_C7645 semialdehyde dehydrogenase, NAD - binding; Belongs to the acetaldehyde dehydrogenase family. (315 aa)
Mvan_05974-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. (338 aa)
Mvan_0669PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: mmc:Mmcs_0502 alcohol dehydrogenase GroES-like protein. (337 aa)
Mvan_1216PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mmc:Mmcs_0905 FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (367 aa)
Mvan_1290PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mmc:Mmcs_0995 FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (394 aa)
Mvan_1327PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: rxy:Rxyl_2822 FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (412 aa)
Mvan_1329PFAM: Rieske [2Fe-2S] domain protein; KEGG: rxy:Rxyl_0167 Rieske (2Fe-2S) region. (118 aa)
Mvan_2243KEGG: mmc:Mmcs_2024 cyclohexanone monooxygenase. (507 aa)
Mvan_2891PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: mmc:Mmcs_0317 glyoxalase/bleomycin resistance protein/dioxygenase. (302 aa)
Mvan_3073PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: mpa:MAP1571 alcohol dehydrogenase. (333 aa)
Mvan_3156PFAM: 4-hydroxyphenylacetate 3-hydroxylase; KEGG: nfa:nfa20870 putative 4-hydroxyphenylacetate 3-hydroxylase. (471 aa)
Mvan_3396PFAM: Carboxymuconolactone decarboxylase; KEGG: mmc:Mmcs_0333 carboxymuconolactone decarboxylase. (266 aa)
Mvan_4167KEGG: mmc:Mmcs_3688 hypothetical protein. (290 aa)
Mvan_4181PFAM: Carboxymuconolactone decarboxylase; KEGG: mmc:Mmcs_3707 carboxymuconolactone decarboxylase. (173 aa)
Mvan_4185PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR; KEGG: mmc:Mmcs_3711 short-chain dehydrogenase/reductase SDR. (248 aa)
mhpBExtradiol ring-cleavage dioxygenase, class III enzyme, subunit B; Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6- ketononatrienedioate, respectively; Belongs to the LigB/MhpB extradiol dioxygenase family. (306 aa)
mhpAMonooxygenase, FAD-binding protein; Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3-hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI). (569 aa)
Mvan_4246PFAM: alpha/beta hydrolase fold; KEGG: mmc:Mmcs_3787 alpha/beta hydrolase fold. (288 aa)
Mvan_4316PFAM: Carboxymuconolactone decarboxylase; KEGG: mmc:Mmcs_3746 carboxymuconolactone decarboxylase. (229 aa)
Mvan_4391Pyruvate carboxyltransferase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. (337 aa)
Mvan_4392Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (318 aa)
Mvan_4393PFAM: Hydratase/decarboxylase; KEGG: nfa:nfa33180 putative hydratase. (283 aa)
Mvan_4405Maleylacetate reductase; PFAM: iron-containing alcohol dehydrogenase; KEGG: cgb:cg3386 maleylacetate reductasetase. (351 aa)
Mvan_44062,4-dichlorophenol 6-monooxygenase; PFAM: monooxygenase, FAD-binding; KEGG: cef:CE2219 putative phenol 2-monooxygenase. (597 aa)
Mvan_4409PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase; KEGG: bha:BH1998 hypothetical protein. (405 aa)
Mvan_4412PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: plu:plu2207 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (276 aa)
Mvan_4414PFAM: alpha/beta hydrolase fold; KEGG: bxe:Bxe_C1186 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase (BphD). (277 aa)
Mvan_4415PFAM: ring hydroxylating dioxygenase, alpha subunit; Rieske [2Fe-2S] domain protein; KEGG: sfx:S2757 large terminal subunit of phenylpropionate dioxygenase. (446 aa)
Mvan_4821PFAM: Carboxymuconolactone decarboxylase; KEGG: mpa:MAP0745c putative 4-carboxymuconolactone decarboxylase. (126 aa)
Mvan_4906PFAM: monooxygenase, FAD-binding; KEGG: sma:SAV563 putative 3-(3-hydroxy-phenyl)propionate hydroxylase. (511 aa)
Mvan_4934PFAM: Carboxymuconolactone decarboxylase; KEGG: sma:SAV6757 4-carboxymuconolactone decarboxylase. (150 aa)
Mvan_4961PFAM: FAD dependent oxidoreductase; KEGG: mmc:Mmcs_4405 cyclohexanone monooxygenase. (613 aa)
Mvan_5154PFAM: Carboxymuconolactone decarboxylase; KEGG: mpa:MAP0605 hypothetical protein. (152 aa)
Mvan_5164PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: mmc:Mmcs_4585 alcohol dehydrogenase GroES-like protein. (376 aa)
Mvan_5234Pyruvate carboxyltransferase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. (350 aa)
Mvan_5235Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (306 aa)
Mvan_5236PFAM: Hydratase/decarboxylase; KEGG: mmc:Mmcs_4661 4-oxalocrotonate decarboxylase. (261 aa)
Mvan_5306PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: mmc:Mmcs_4707 glyoxalase/bleomycin resistance protein/dioxygenase. (300 aa)
Mvan_5307PFAM: alpha/beta hydrolase fold; KEGG: mmc:Mmcs_4708 alpha/beta hydrolase fold. (295 aa)
Mvan_5450PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ape:APE2239 alcohol dehydrogenase. (356 aa)
Mvan_5476PFAM: iron-containing alcohol dehydrogenase; KEGG: rha:RHA1_ro06060 1,3-propanediol dehydrogenase. (402 aa)
Your Current Organism:
Mycolicibacterium vanbaalenii
NCBI taxonomy Id: 350058
Other names: M. vanbaalenii PYR-1, Mycobacterium sp. PYR-1, Mycobacterium vanbaalenii DSM 7251, Mycobacterium vanbaalenii PYR-1, Mycolicibacterium vanbaalenii DSM 7251, Mycolicibacterium vanbaalenii PYR-1
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