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Clos_0008 Clos_0008 Clos_0009 Clos_0009 Clos_0010 Clos_0010 Clos_0052 Clos_0052 Clos_0186 Clos_0186 Clos_0241 Clos_0241 Clos_0250 Clos_0250 Clos_0265 Clos_0265 Clos_0354 Clos_0354 Clos_0385 Clos_0385 Clos_0543 Clos_0543 Clos_0881 Clos_0881 Clos_0897 Clos_0897 Clos_1056 Clos_1056 Clos_1192 Clos_1192 Clos_1476 Clos_1476 Clos_1477 Clos_1477 fliE fliE Clos_1479 Clos_1479 Clos_1480 Clos_1480 Clos_1481 Clos_1481 Clos_1482 Clos_1482 Clos_1483 Clos_1483 Clos_1485 Clos_1485 Clos_1486 Clos_1486 Clos_1487 Clos_1487 Clos_1488 Clos_1488 Clos_1489 Clos_1489 Clos_1490 Clos_1490 Clos_1491 Clos_1491 Clos_1492 Clos_1492 Clos_1494 Clos_1494 Clos_1495 Clos_1495 Clos_1496 Clos_1496 fliP fliP fliQ fliQ Clos_1499 Clos_1499 flhB flhB flhA flhA Clos_1502 Clos_1502 Clos_1503 Clos_1503 Clos_1504 Clos_1504 cheB cheB Clos_1506 Clos_1506 Clos_1507 Clos_1507 Clos_1508 Clos_1508 cheD cheD Clos_1510 Clos_1510 Clos_1511 Clos_1511 Clos_1560 Clos_1560 Clos_1640 Clos_1640 Clos_1960 Clos_1960 Clos_2075 Clos_2075 Clos_2100 Clos_2100 Clos_2128 Clos_2128 Clos_2204 Clos_2204 Clos_2370 Clos_2370 Clos_2384 Clos_2384 Clos_2478 Clos_2478 Clos_2479 Clos_2479 Clos_2482 Clos_2482 Clos_2483 Clos_2483 Clos_2489 Clos_2489 Clos_2490 Clos_2490 Clos_2491 Clos_2491 csrA csrA fliW fliW Clos_2518 Clos_2518 Clos_2519 Clos_2519 Clos_2520 Clos_2520 flgK flgK Clos_2522 Clos_2522 Clos_2523 Clos_2523 Clos_2524 Clos_2524 Clos_2548 Clos_2548 Clos_2549 Clos_2549 Clos_2550 Clos_2550 Clos_2609 Clos_2609 Clos_2789 Clos_2789
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Clos_0008Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: amt:Amet_0008 anti-sigma-factor antagonist. (105 aa)
Clos_0009KEGG: amt:Amet_0009 putative anti-sigma regulatory factor, serine/threonine protein kinase. (142 aa)
Clos_0010RNA polymerase, sigma 28 subunit, FliA/WhiG family; TIGRFAM: RNA polymerase sigma-70; RNA polymerase sigma-B/F/G type; PFAM: sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: amt:Amet_0010 phage transcriptional regulator, RinA family; Belongs to the sigma-70 factor family. (270 aa)
Clos_0052PFAM: chemotaxis sensory transducer; KEGG: amt:Amet_0043 methyl-accepting chemotaxis sensory transducer. (495 aa)
Clos_0186PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: dsy:DSY0350 hypothetical protein. (533 aa)
Clos_0241PFAM: histidine kinase HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer; KEGG: amt:Amet_2943 methyl-accepting chemotaxis sensory transducer. (666 aa)
Clos_0250PFAM: histidine kinase HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer; KEGG: amt:Amet_4638 methyl-accepting chemotaxis sensory transducer. (663 aa)
Clos_0265PFAM: histidine kinase HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer; KEGG: tte:TTE2231 methyl-accepting chemotaxis protein. (705 aa)
Clos_0354PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: dsy:DSY3380 hypothetical protein. (672 aa)
Clos_0385PFAM: chemotaxis sensory transducer; KEGG: ctc:CTC01155 methyl-accepting chemotaxis protein. (489 aa)
Clos_0543PFAM: chemotaxis sensory transducer; KEGG: tte:TTE0646 methyl-accepting chemotaxis protein. (263 aa)
Clos_0881PFAM: chemotaxis sensory transducer; KEGG: mba:Mbar_A0989 methyl-accepting chemotaxis protein. (510 aa)
Clos_0897PFAM: chemotaxis sensory transducer; KEGG: cbo:CBO1558 methyl-accepting chemotaxis protein. (317 aa)
Clos_1056PFAM: chemotaxis sensory transducer; KEGG: bcz:BCZK1024 methyl-accepting chemotaxis protein. (567 aa)
Clos_1192PFAM: CheW domain protein; KEGG: chy:CHY_0966 chemotaxis protein CheW. (151 aa)
Clos_1476Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body. (131 aa)
Clos_1477TIGRFAM: flagellar basal-body rod protein FlgC; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: cth:Cthe_0463 flagellar basal-body rod protein FlgC. (147 aa)
fliETIGRFAM: flagellar hook-basal body complex subunit FliE; PFAM: flagellar hook-basal body complex protein FliE; KEGG: tte:TTE1443 flagellar hook-basal body protein. (99 aa)
Clos_1479Flagellar M-ring protein FliF; The M ring may be actively involved in energy transduction. Belongs to the FliF family. (515 aa)
Clos_1480PFAM: flagellar motor switch protein FliG; KEGG: cth:Cthe_0466 flagellar motor switch protein FliG. (339 aa)
Clos_1481PFAM: flagellar assembly protein FliH; KEGG: tte:TTE1440 flagellar biosynthesis/type III secretory pathway protein. (269 aa)
Clos_1482KEGG: cth:Cthe_0468 flagellar protein export ATPase FliI; TIGRFAM: ATPase, FliI/YscN family; flagellar protein export ATPase FliI; type III secretion apparatus H+-transporting two-sector ATPase; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; H+transporting two-sector ATPase alpha/beta subunit domain protein; SMART: AAA ATPase. (437 aa)
Clos_1483TIGRFAM: flagellar export protein FliJ; KEGG: cth:Cthe_0469 flagellar export protein FliJ. (146 aa)
Clos_1485PFAM: flagellar hook-length control protein; KEGG: cth:Cthe_0471 flagellar hook-length control protein. (485 aa)
Clos_1486PFAM: flagellar hook capping protein; KEGG: dvl:Dvul_1635 flagellar hook capping protein. (141 aa)
Clos_1487TIGRFAM: flagellar operon protein; KEGG: cth:Cthe_0473 flagellar operon protein. (128 aa)
Clos_1488PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; flagellar basal body FlaE domain protein; KEGG: cth:Cthe_0474 protein of unknown function DUF1078-like protein. (448 aa)
Clos_1489PFAM: flagellar FlbD family protein; KEGG: tte:TTE1432 uncharacterized protein, possibly involved in motility. (71 aa)
Clos_1490PFAM: MotA/TolQ/ExbB proton channel; KEGG: dde:Dde_3589 chemotaxis protein MotA. (261 aa)
Clos_1491PFAM: OmpA/MotB domain protein; KEGG: mta:Moth_0782 OmpA/MotB. (254 aa)
Clos_1492Flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family. (141 aa)
Clos_1494CheC, inhibitor of MCP methylation / FliN fusion protein; TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein; CheC domain protein; KEGG: cth:Cthe_0478 CheC, inhibitor of MCP methylation. (385 aa)
Clos_1495PFAM: response regulator receiver; KEGG: csc:Csac_1271 response regulator receiver protein. (120 aa)
Clos_1496KEGG: amt:Amet_2708 hypothetical protein. (114 aa)
fliPFlagellar biosynthetic protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family. (269 aa)
fliQFlagellar biosynthetic protein FliQ; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family. (89 aa)
Clos_1499Flagellar biosynthetic protein FliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family. (262 aa)
flhBFlagellar biosynthetic protein FlhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family. (362 aa)
flhAFlagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. (675 aa)
Clos_1502PFAM: GTP-binding signal recognition particle SRP54 G- domain; SMART: AAA ATPase; KEGG: amt:Amet_2702 GTP-binding signal recognition particle SRP54, G-domain. (409 aa)
Clos_1503PFAM: Cobyrinic acid ac-diamide synthase; KEGG: amt:Amet_2701 cobyrinic acid a,c-diamide synthase. (300 aa)
Clos_1504PFAM: type IV pilus assembly PilZ; KEGG: amt:Amet_2700 type IV pilus assembly PilZ. (218 aa)
cheBResponse regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (358 aa)
Clos_1506CheA signal transduction histidine kinase; PFAM: CheW domain protein; ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; P2 response regulator binding domain protein; KEGG: cth:Cthe_0490 CheA signal transduction histidine kinases. (692 aa)
Clos_1507PFAM: CheW domain protein; KEGG: cth:Cthe_0491 CheW protein. (145 aa)
Clos_1508PFAM: CheC domain protein; KEGG: cth:Cthe_0492 CheC, inhibitor of MCP methylation. (205 aa)
cheDCheD, stimulates methylation of MCP proteins; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family. (161 aa)
Clos_1510RNA polymerase, sigma 28 subunit, FliA/WhiG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (245 aa)
Clos_1511PFAM: protein of unknown function DUF342; KEGG: cth:Cthe_0498 protein of unknown function DUF342. (602 aa)
Clos_1560PFAM: MCP methyltransferase CheR-type; KEGG: cth:Cthe_0717 MCP methyltransferase, CheR-type. (257 aa)
Clos_1640KEGG: tte:TTE0491 flagellar protein. (143 aa)
Clos_1960PFAM: response regulator receiver; CheW domain protein; KEGG: bha:BH2262 modulation of CheA activity in response to attractants (chemotaxis protein). (303 aa)
Clos_2075PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; Cache type 2 domain protein; KEGG: cbo:CBO2811 methyl-accepting chemotaxis protein. (602 aa)
Clos_2100PFAM: response regulator receiver; Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: sat:SYN_00230 response regulator receiver domain and a sigma factor phosphatase domain. (403 aa)
Clos_2128PFAM: chemotaxis sensory transducer; Heme NO binding domain protein; KEGG: tte:TTE0680 methyl-accepting chemotaxis protein. (603 aa)
Clos_2204PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: dsy:DSY3380 hypothetical protein. (662 aa)
Clos_2370PFAM: histidine kinase HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer; KEGG: dsy:DSY4989 hypothetical protein. (679 aa)
Clos_2384PFAM: histidine kinase HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer; KEGG: bha:BH3903 methyl-accepting chemotaxis protein. (712 aa)
Clos_2478PFAM: flagellar protein FliS; KEGG: mta:Moth_0766 flagellar protein FliS. (161 aa)
Clos_2479Flagellin domain protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. (538 aa)
Clos_2482PFAM: protein of unknown function DUF327; KEGG: cth:Cthe_2106 protein of unknown function DUF327. (148 aa)
Clos_2483PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: bld:BLi03297 close homolog to McpA methyl-accepting chemotaxis protein; RBL01413. (791 aa)
Clos_2489PFAM: flagellar protein FliS; KEGG: tte:TTE0506 Flagellar protein. (126 aa)
Clos_2490Flagellar hook-associated 2 domain protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end. (662 aa)
Clos_2491PFAM: flagellar protein FlaG protein; KEGG: cth:Cthe_2219 flagellar protein FlaG protein. (119 aa)
csrACarbon storage regulator, CsrA; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW. (74 aa)
fliWProtein of unknown function DUF180; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum. (159 aa)
Clos_2518Flagellin domain protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. (270 aa)
Clos_2519PFAM: histidine kinase HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer; KEGG: cbo:CBO0693 methyl-accepting chemotaxis protein. (667 aa)
Clos_2520TIGRFAM: flagellar hook-associated protein 3; PFAM: flagellin domain protein; KEGG: bha:BH3620 flagellar hook-associated protein 3 (HAP3). (438 aa)
flgKTIGRFAM: flagellar hook-associated protein FlgK; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: cth:Cthe_2243 flagellar hook-associated protein FlgK. (522 aa)
Clos_2522KEGG: cth:Cthe_2245 hypothetical protein. (164 aa)
Clos_2523KEGG: cth:Cthe_2246 anti-sigma-28 factor, FlgM. (97 aa)
Clos_2524KEGG: csc:Csac_1661 hypothetical protein. (141 aa)
Clos_2548KEGG: cth:Cthe_2622 hypothetical protein. (120 aa)
Clos_2549PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: tte:TTE0173 Flagellar basal body and hook proteins. (264 aa)
Clos_2550PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: tte:TTE0172 Flagellar basal body and hook proteins. (357 aa)
Clos_2609PFAM: histidine kinase HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer; KEGG: dsy:DSY4989 hypothetical protein. (666 aa)
Clos_2789PFAM: chemotaxis sensory transducer; KEGG: cbo:CBO0693 methyl-accepting chemotaxis protein. (633 aa)
Your Current Organism:
Alkaliphilus oremlandii
NCBI taxonomy Id: 350688
Other names: A. oremlandii OhILAs, Alkaliphilus oremlandii OhILAs, Alkaliphilus oremlandii str. OhILAs, Alkaliphilus oremlandii strain OhILAs, Clostridium oremlandii OhILAs, Clostridium sp. OhILAs
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