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| | aif2 | Translation initiation factor 2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. (594 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (152 aa) |
| | rps28e | 30S ribosomal protein S28E; Belongs to the eukaryotic ribosomal protein eS28 family. (70 aa) |
| | rpl7ae | 50S ribosomal protein L7AE; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (123 aa) |
| | rpl12p | Putative 50S ribosomal protein L12P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (103 aa) |
| | rpl10e | 50S ribosomal protein L10E; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (304 aa) |
| | rpl1p | 50S ribosomal protein L1P; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (213 aa) |
| | rpl11p | 50S ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (158 aa) |
| | secE | Putative preprotein translocase, subunit E; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (71 aa) |
| | eif2a | Translation initiation factor 2, alpha subunit. (267 aa) |
| | rps27e | 30S ribosomal protein S27E. (58 aa) |
| | rpl44e | 50S ribosomal protein L44E; Binds to the 23S rRNA. (93 aa) |
| | eif1a-1 | Translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (112 aa) |
| | rpl30e | 50S ribosomal protein L30E; Belongs to the eukaryotic ribosomal protein eL30 family. (101 aa) |
| | nusA | Transcription termination factor NusA; Participates in transcription termination. Belongs to the NusA family. (146 aa) |
| | rps12p | 30S ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (142 aa) |
| | rps7p | 30S ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (206 aa) |
| | fusA | Translation elongation factor 2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] (732 aa) |
| | tuf-1 | Translation elongation factor 1, alpha subunit; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (426 aa) |
| | rps10p | 30S ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (104 aa) |
| | LRC37 | Conserved hypothetical protein. (152 aa) |
| | rps2p | 30S ribosomal protein S2P; Belongs to the universal ribosomal protein uS2 family. (207 aa) |
| | rps9p | 30S ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family. (136 aa) |
| | rpl13p | 50S ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (139 aa) |
| | rpl18e | 50S ribosomal protein L18E; Belongs to the eukaryotic ribosomal protein eL18 family. (120 aa) |
| | rps6e | 30S ribosomal protein S6E; Belongs to the eukaryotic ribosomal protein eS6 family. (142 aa) |
| | eif5a | Translation initiation factor 5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. (128 aa) |
| | rps15p | 30S ribosomal protein S15P. (152 aa) |
| | LRC61 | Predicted protease (Mov34 family). (136 aa) |
| | eif1a-2 | Translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (96 aa) |
| | RCIA82 | Conserved GTP-binding protein. (361 aa) |
| | nac | Putative transcription factor (alpha-NAC related); Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family. (131 aa) |
| | ftsY | Putative signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (377 aa) |
| | rplX | 50S ribosomal protein LX. (58 aa) |
| | rpl31e | 50S ribosomal protein L31E; Belongs to the eukaryotic ribosomal protein eL31 family. (91 aa) |
| | rps19e | 30S ribosomal protein S19E; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (146 aa) |
| | RCIX1090 | Predicted Zn-finger protein interacting with DnaK (DnaJ-like). (494 aa) |
| | eif1a-3 | Translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (112 aa) |
| | RCIX1138 | Predicted protein interacting with DnaK (DnaJ-like). (242 aa) |
| | RCIX1210 | RNase L inhibitor. (590 aa) |
| | RCIX127 | Conserved hypothetical protein. (157 aa) |
| | RCIX1378 | Conserved hypothetical protein. (59 aa) |
| | ef1b | Translation elongation factor 1, beta subunit; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. (89 aa) |
| | rpl40e | 50S ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family. (48 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (525 aa) |
| | eif2b-1 | Translation initiation factor 2, beta subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. (204 aa) |
| | rpl10e-2 | 50S ribosomal protein L10E; Belongs to the universal ribosomal protein uL16 family. (172 aa) |
| | eif2g | Translation initiation factor 2, gamma subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. (408 aa) |
| | srp19 | Signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP. (97 aa) |
| | rpl15e | 50S ribosomal protein L15E; Belongs to the eukaryotic ribosomal protein eL15 family. (196 aa) |
| | RCIX2122 | Conserved hypothetical protein. (231 aa) |
| | rpl37ae | 50S ribosomal protein L37AE; Binds to the 23S rRNA. (96 aa) |
| | eif2b-2 | Translation initiation factor 2, beta subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. (135 aa) |
| | rps3ae | 30S ribosomal protein S3AE; Belongs to the eukaryotic ribosomal protein eS1 family. (225 aa) |
| | srp54 | Signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (444 aa) |
| | rpl21e | 50S ribosomal protein L21E; Belongs to the eukaryotic ribosomal protein eL21 family. (99 aa) |
| | map-1 | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val); Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily. (293 aa) |
| | RCIX2456 | Putative transcription factor. (166 aa) |
| | rpl3p | 50S ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (337 aa) |
| | rpl4p | 50S ribosomal protein L4P; Forms part of the polypeptide exit tunnel. (253 aa) |
| | rpl23p | 50S ribosomal protein L23P; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (82 aa) |
| | rpl2p | 50S ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (238 aa) |
| | rps19p | 30S ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (140 aa) |
| | rpl22p | 50S ribosomal protein L22P; This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (153 aa) |
| | rps3p | 30S ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (279 aa) |
| | rpl29p | 50S ribosomal protein L29P; Belongs to the universal ribosomal protein uL29 family. (71 aa) |
| | RCIX2550 | Translation initiation factor (SUI1 family); Belongs to the SUI1 family. (101 aa) |
| | rps17p | 30S ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (111 aa) |
| | rpl14p | 50S ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (132 aa) |
| | rpl24p | 50S ribosomal protein L24P; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (123 aa) |
| | rps4e | 30S ribosomal protein S4E; Belongs to the eukaryotic ribosomal protein eS4 family. (234 aa) |
| | rpl5p | 50S ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (170 aa) |
| | rps14p | 30S ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles. (50 aa) |
| | rps8p | 30S ribosomal protein S8P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa) |
| | rpl6p | 50S ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (177 aa) |
| | rpl32e | Putative 50S ribosomal protein L32E. (221 aa) |
| | rpl19e | 50S ribosomal protein L19E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (152 aa) |
| | rpl18p | 50S ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (188 aa) |
| | rps5p | 30S ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy. (212 aa) |
| | rpl30p | 50S ribosomal protein L30P. (153 aa) |
| | rpl15p | 50S ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (146 aa) |
| | secY | Protein translocase, subunit Y; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (508 aa) |
| | rps13p | Putative 30S ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (224 aa) |
| | rps4p | 30S ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (205 aa) |
| | rps11p | 30S ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (132 aa) |
| | rps8e | 30S ribosomal protein S8E. (125 aa) |
| | erf1 | Translation termination factor; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. (417 aa) |
| | rps27ae | 30S ribosomal protein S27AE; Belongs to the eukaryotic ribosomal protein eS31 family. (44 aa) |
| | rps17e | 30s ribosomal protein S17E; Belongs to the eukaryotic ribosomal protein eS17 family. (65 aa) |
| | tuf-2 | Translation elongation factor 1, alpha subunit. (345 aa) |
| | RRC313 | Translation initiation factor (SUI1 family); Belongs to the SUI1 family. (101 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (474 aa) |
