STRINGSTRING
LRC236 LRC236 LRC237 LRC237 LRC263 LRC263 LRC265 LRC265 LRC271 LRC271 LRC275 LRC275 LRC278 LRC278 LRC279 LRC279 rpl26e rpl26e tgt-1 tgt-1 LRC292 LRC292 LRC298 LRC298 LRC429 LRC429 LRC435 LRC435 LRC520 LRC520 LRC539 LRC539 LRC541 LRC541 LRC57 LRC57 RCIX1015 RCIX1015 RCIX1020 RCIX1020 RCIX1118 RCIX1118 RCIX1120 RCIX1120 RCIX1140 RCIX1140 RCIX1141 RCIX1141 RCIX1172 RCIX1172 RCIX1209 RCIX1209 RCIX1235 RCIX1235 RCIX1248 RCIX1248 RCIX1274 RCIX1274 RCIX1276 RCIX1276 tiaS tiaS RCIX1430 RCIX1430 mptD mptD RCIX1546 RCIX1546 RCIX1549 RCIX1549 RCIX1640 RCIX1640 RCIX1732 RCIX1732 serB-1 serB-1 RCIX1743 RCIX1743 RCIX1843 RCIX1843 RCIX1844 RCIX1844 RCIX1848 RCIX1848 RCIX1858 RCIX1858 RCIX1860 RCIX1860 RCIX2021 RCIX2021 recJ recJ RCIX2104 RCIX2104 RCIX2215 RCIX2215 gsp-9 gsp-9 gsp-10 gsp-10 RCIX2245 RCIX2245 RCIX2250 RCIX2250 trmY trmY RCIX2571 RCIX2571 RCIX2572 RCIX2572 RCIX2680 RCIX2680 tgt-2 tgt-2 RCIX2741 RCIX2741 RCIX282 RCIX282 dnaG dnaG mptE mptE RCIX396 RCIX396 RCIX403 RCIX403 RCIX407 RCIX407 RCIX408 RCIX408 RCIX415 RCIX415 RCIX452 RCIX452 RCIX502 RCIX502 RCIX529 RCIX529 RCIX587 RCIX587 rpoE2 rpoE2 RCIX625 RCIX625 RCIX689 RCIX689 RCIX690 RCIX690 RCIX703 RCIX703 pol2b pol2b RRC100 RRC100 RRC101 RRC101 endA endA dacZ dacZ RRC338 RRC338 RRC517 RRC517
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LRC236Conserved hypothetical protein. (124 aa)
LRC237Predicted Zn-finger protein (ZPR1-type). (198 aa)
LRC263Hypothetical protein. (338 aa)
LRC265Conserved hypothetical protein. (278 aa)
LRC271Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. (178 aa)
LRC275Conserved hypothetical protein. (217 aa)
LRC278Conserved hypothetical protein. (167 aa)
LRC279Conserved hypothetical protein. (338 aa)
rpl26e50S ribosomal protein L26E; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. (164 aa)
tgt-1Archaeosine tRNA-ribosyltransferase. (589 aa)
LRC292Predicted 3-isopropylmalate dehydratase. (254 aa)
LRC298Hypothetical protein; Identical to orf9 of fosmid clone 3D10mr4. (176 aa)
LRC429Conserved hypothetical protein. (166 aa)
LRC435Conserved hypothetical protein; Belongs to the UPF0179 family. (148 aa)
LRC520Hypothetical protein. (218 aa)
LRC539Transmembrane oligosaccharyltransferase. (939 aa)
LRC541Transmembrane oligosaccharyltransferase. (950 aa)
LRC57Putative single-stranded DNA-specific exonuclease (RecJ-like). (430 aa)
RCIX1015Signal sequence peptidase; Similar to orf41 of fosmid clone 1B6mr2. (186 aa)
RCIX1020Conserved hypothetical protein. (307 aa)
RCIX1118Putative signal sequence peptidase; Similar to orf41 of fosmid clone 1B6mr2. (185 aa)
RCIX1120Putative signal sequence peptidase; Similar to orf41 of fosmid clone 1B6mr2. (183 aa)
RCIX1140Transcription regulator (Crp family). (258 aa)
RCIX1141Conserved hypothetical protein. (172 aa)
RCIX1172Conserved hypothetical protein. (127 aa)
RCIX1209Hypothetical protein. (113 aa)
RCIX1235Conserved hypothetical protein. (224 aa)
RCIX1248Conserved hypothetical protein. (675 aa)
RCIX1274Putative transcription regulator (ArsR family). (282 aa)
RCIX1276Putative phosphoesterase. (495 aa)
tiaSConserved hypothetical protein; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. (421 aa)
RCIX1430Predicted transcription regulator. (324 aa)
mptDConserved hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD); Belongs to the archaeal dihydroneopterin aldolase family. (116 aa)
RCIX1546Conserved hypothetical protein. (127 aa)
RCIX1549Conserved hypothetical protein; Similar to orf20 (predicted lipoate synthase) of fosmid clone 1B6mr2. (330 aa)
RCIX1640Conserved hypothetical protein. (138 aa)
RCIX1732Conserved hypothetical protein. (367 aa)
serB-1Putative phosphoserine phosphatase. (286 aa)
RCIX1743Conserved hypothetical protein. (185 aa)
RCIX1843Conserved hypothetical protein. (247 aa)
RCIX1844Conserved hypothetical protein. (112 aa)
RCIX1848Putative TatD-related deoxyribonuclease. (281 aa)
RCIX1858Conserved hypothetical protein. (159 aa)
RCIX1860Conserved hypothetical protein. (113 aa)
RCIX2021Putative phosphoesterase. (319 aa)
recJPutative single-stranded DNA-specific exonuclease. (461 aa)
RCIX2104Conserved hypothetical protein. (199 aa)
RCIX2215Conserved hypothetical protein. (250 aa)
gsp-9Putative bacterial type II secretion system protein. (683 aa)
gsp-10Putative bacterial type II secretion system protein. (700 aa)
RCIX2245Conserved hypothetical protein. (97 aa)
RCIX2250Predicted peptidase (A24 family). (272 aa)
trmYConserved hypothetical protein; Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs; Belongs to the methyltransferase superfamily. TrmY family. (192 aa)
RCIX2571Conserved hypothetical protein. (207 aa)
RCIX2572Conserved hypothetical protein. (217 aa)
RCIX2680Conserved hypothetical protein. (291 aa)
tgt-2Archaeosine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. (487 aa)
RCIX2741Putative phosphoesterase. (325 aa)
RCIX282Conserved hypothetical protein. (88 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. (481 aa)
mptEConserved hypothetical protein; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family. (211 aa)
RCIX396Predicted redox-active protein (CxxC motif). (557 aa)
RCIX403Conserved hypothetical protein. (220 aa)
RCIX407Conserved hypothetical protein. (307 aa)
RCIX408Conserved hypothetical protein. (193 aa)
RCIX415Putative archaeosine tRNA-ribosyltransferase. (159 aa)
RCIX452Conserved hypothetical protein. (99 aa)
RCIX502Conserved hypothetical protein. (100 aa)
RCIX529Conserved hypothetical protein; Involved in DNA damage repair. (414 aa)
RCIX587Conserved hypothetical protein. (428 aa)
rpoE2Putative DNA-directed RNA polymerase, subunit E2; Stimulates transcription elongation; Belongs to the archaeal Spt4 family. (75 aa)
RCIX625Conserved hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). (176 aa)
RCIX689Conserved hypothetical protein. (230 aa)
RCIX690Conserved hypothetical protein. (83 aa)
RCIX703Conserved hypothetical protein. (248 aa)
pol2bDNA-directed DNA polymerase D, large subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity). (1134 aa)
RRC100Conserved hypothetical protein. (174 aa)
RRC101Small nuclear riboprotein-like protein. (74 aa)
endAtRNA-splicing endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp. (353 aa)
dacZConserved hypothetical protein; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. (289 aa)
RRC338Conserved hypothetical protein. (125 aa)
RRC517Conserved hypothetical protein. (322 aa)
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
Server load: low (16%) [HD]