STRINGSTRING
LRC112 LRC112 LRC128 LRC128 LRC129 LRC129 LRC131 LRC131 top6A-1 top6A-1 top6B-1 top6B-1 rps28e rps28e rpl7ae rpl7ae polB-1 polB-1 LRC159 LRC159 LRC222 LRC222 LRC223 LRC223 LRC226 LRC226 LRC23 LRC23 LRC235 LRC235 rpl12p rpl12p rpl10e rpl10e LRC251 LRC251 rpl1p rpl1p LRC263 LRC263 LRC268 LRC268 rpl11p rpl11p tfeA tfeA rpl26e rpl26e LRC289 LRC289 rps27e rps27e rpl44e rpl44e priA priA LRC3 LRC3 LRC300 LRC300 LRC345 LRC345 LRC353 LRC353 rpl30e rpl30e rps12p rps12p rps7p rps7p rps10p rps10p rfcS rfcS LRC392 LRC392 LRC400 LRC400 rps2p rps2p rps9p rps9p rpl13p rpl13p rpl18e rpl18e rps6e rps6e LRC45 LRC45 rad25 rad25 dnaK dnaK LRC473 LRC473 LRC482 LRC482 mutSb mutSb LRC529 LRC529 rps15p rps15p mutSa mutSa LRC65 LRC65 LRC70 LRC70 LRC94 LRC94 RCIX1018 RCIX1018 nac nac hmgA hmgA rplX rplX rpl31e rpl31e rps19e rps19e RCIX107 RCIX107 top6B-2 top6B-2 top6A-2 top6A-2 mpg mpg RCIX1108 RCIX1108 cdc6-1 cdc6-1 cdc48-3 cdc48-3 RCIX115 RCIX115 RCIX117 RCIX117 polX polX RCIX1210 RCIX1210 xthA xthA tbpE tbpE RCIX1257 RCIX1257 RCIX1263 RCIX1263 RCIX1272 RCIX1272 RCIX1310 RCIX1310 RCIX1333 RCIX1333 RCIX1335 RCIX1335 RCIX1340 RCIX1340 RCIX1428 RCIX1428 rpl40e rpl40e RCIX1585 RCIX1585 RCIX1603 RCIX1603 nifH-1 nifH-1 RCIX1654 RCIX1654 hpyA1 hpyA1 RCIX1761 RCIX1761 recQ recQ rfcL rfcL cdc6-2 cdc6-2 RCIX1862 RCIX1862 RCIX1863 RCIX1863 RCIX1864 RCIX1864 RCIX1866 RCIX1866 RCIX1867 RCIX1867 RCIX1868 RCIX1868 RCIX1934 RCIX1934 RCIX1966 RCIX1966 rpl10e-2 rpl10e-2 nifH-2 nifH-2 cbiX-1 cbiX-1 RCIX2018 RCIX2018 RCIX209 RCIX209 RCIX210 RCIX210 RCIX2110 RCIX2110 rpl15e rpl15e RCIX2122 RCIX2122 rpl37ae rpl37ae RCIX214 RCIX214 kptA kptA RCIX2178 RCIX2178 RCIX2198 RCIX2198 RCIX2215 RCIX2215 rbcL rbcL truA truA RCIX2249 RCIX2249 smc smc eif2b1 eif2b1 rps3ae rps3ae repD repD tfs tfs priB priB topA-1 topA-1 RCIX2327 RCIX2327 hmfA hmfA pus10 pus10 rpl21e rpl21e RCIX2394 RCIX2394 ugd ugd RCIX2412 RCIX2412 gatB-1 gatB-1 topA-2 topA-2 RCIX2438 RCIX2438 RCIX2456 RCIX2456 adk-1 adk-1 albA albA RCIX2472 RCIX2472 RCIX2491 RCIX2491 RCIX2497 RCIX2497 RCIX2501 RCIX2501 RCIX2525 RCIX2525 dcm dcm RCIX2536 RCIX2536 rpl3p rpl3p rpl4p rpl4p rpl23p rpl23p rpl2p rpl2p rps19p rps19p rpl22p rpl22p rps3p rps3p rpl29p rpl29p rps17p rps17p rpl14p rpl14p rpl24p rpl24p rps4e rps4e rpl5p rpl5p rps14p rps14p rps8p rps8p rpl6p rpl6p rpl32e rpl32e rpl19e rpl19e rpl18p rpl18p rps5p rps5p rpl30p rpl30p rpl15p rpl15p truB truB rps13p rps13p rps4p rps4p rps11p rps11p rps8e rps8e RCIX2705 RCIX2705 trm1 trm1 RCIX2726 RCIX2726 polB-3 polB-3 RCIX28 RCIX28 dnaG dnaG RCIX292 RCIX292 RCIX293 RCIX293 RCIX305 RCIX305 ptpS ptpS RCIX360 RCIX360 hmgA-2 hmgA-2 RCIX407 RCIX407 RCIX455 RCIX455 RCIX492 RCIX492 hel308 hel308 gyrA gyrA RCIX580 RCIX580 gyrB gyrB fen fen rps27ae rps27ae RCIX628 RCIX628 cdc48-1 cdc48-1 cdc48-2 cdc48-2 rnz rnz RCIX72 RCIX72 rps17e rps17e pycA pycA ppiB ppiB RCIX759 RCIX759 RCIX807 RCIX807 RCIX819 RCIX819 ubiE ubiE RCIX894 RCIX894 RCIX900 RCIX900 hemA hemA cysG cysG lysM lysM RCIX924 RCIX924 RCIX925 RCIX925 RCIX927 RCIX927 RCIX977 RCIX977 cbiX-2 cbiX-2 RRC12 RRC12 pdhB pdhB pdhA pdhA endA endA RRC248 RRC248 RRC278 RRC278 RRC290 RRC290 RRC295 RRC295 nfo nfo RRC355 RRC355 polB-4 polB-4 RRC405 RRC405 RRC430 RRC430 ubiX ubiX RRC451 RRC451 RRC454 RRC454 RRC49 RRC49 RRC51 RRC51 RRC53 RRC53 aat-4 aat-4 RRC63 RRC63 RRC95 RRC95
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LRC112Conserved hypothetical protein; Belongs to the UPF0145 family. (120 aa)
LRC128Predicted regulator of chromosome condensation. (490 aa)
LRC129Predicted methyltransferase (UbiE/COQ5 family). (299 aa)
LRC131Thioredoxin-like protein. (195 aa)
top6A-1Type II DNA topoisomerase VI, subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. (366 aa)
top6B-1Type II DNA topoisomerase VI, subunit B; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. (541 aa)
rps28e30S ribosomal protein S28E; Belongs to the eukaryotic ribosomal protein eS28 family. (70 aa)
rpl7ae50S ribosomal protein L7AE; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (123 aa)
polB-1DNA-directed DNA polymerase B. (918 aa)
LRC159Conserved hypothetical protein. (181 aa)
LRC222Conserved hypothetical Fe-S cluster-binding protein, N-terminal fragment. (107 aa)
LRC223Conserved hypothetical Fe-S cluster-binding protein, C-terminal fragment. (202 aa)
LRC226Thioredoxin-like protein. (174 aa)
LRC23Putative ATPase (KaiC family). (254 aa)
LRC235Conserved hypothetical protein. (162 aa)
rpl12pPutative 50S ribosomal protein L12P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (103 aa)
rpl10e50S ribosomal protein L10E; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (304 aa)
LRC251Conserved hypothetical protein. (391 aa)
rpl1p50S ribosomal protein L1P; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (213 aa)
LRC263Hypothetical protein. (338 aa)
LRC268Predicted N6 adenine-specific DNA methyltransferase. (225 aa)
rpl11p50S ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (158 aa)
tfeATranscription initiation factor IIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing [...] (171 aa)
rpl26e50S ribosomal protein L26E; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. (164 aa)
LRC289Conserved hypothetical protein; Identical to orf4 of fosmid clone 3D10mr4. (181 aa)
rps27e30S ribosomal protein S27E. (58 aa)
rpl44e50S ribosomal protein L44E; Binds to the 23S rRNA. (93 aa)
priADNA primase, small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...] (400 aa)
LRC3ATP-dependent RNA helicase. (746 aa)
LRC300Hypothetical protein; Identical to orf11 of fosmid clone 3D10mr4. (201 aa)
LRC345ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. (497 aa)
LRC353mRNA 3-end processing factor. (432 aa)
rpl30e50S ribosomal protein L30E; Belongs to the eukaryotic ribosomal protein eL30 family. (101 aa)
rps12p30S ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (142 aa)
rps7p30S ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (206 aa)
rps10p30S ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (104 aa)
rfcSReplication factor C (clamp loader), small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily. (322 aa)
LRC392Fumarylacetoacetate hydrolase family protein. (242 aa)
LRC400Conserved hypothetical protein; Belongs to the MEMO1 family. (264 aa)
rps2p30S ribosomal protein S2P; Belongs to the universal ribosomal protein uS2 family. (207 aa)
rps9p30S ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family. (136 aa)
rpl13p50S ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (139 aa)
rpl18e50S ribosomal protein L18E; Belongs to the eukaryotic ribosomal protein eL18 family. (120 aa)
rps6e30S ribosomal protein S6E; Belongs to the eukaryotic ribosomal protein eS6 family. (142 aa)
LRC45Conserved hypothetical protein. (210 aa)
rad25Putative DNA repair protein 25. (446 aa)
dnaKChaperonin Hsp70; Acts as a chaperone. (623 aa)
LRC473Predicted RecA-family ATPase. (241 aa)
LRC482Conserved hypothetical protein. (225 aa)
mutSbPutative DNA mismatch repair protein, N-terminal fragment. (565 aa)
LRC529Pedicted SAM-dependent methyltransferase. (211 aa)
rps15p30S ribosomal protein S15P. (152 aa)
mutSaPutative DNA mismatch repair protein, C-terminal fragment. (122 aa)
LRC65Conserved hypothetical protein. (157 aa)
LRC70Putative DNA/RNA helicase (SNF2 family). (1042 aa)
LRC94Hypothetical protein. (191 aa)
RCIX1018Conserved hypothetical GTP-binding protein. (355 aa)
nacPutative transcription factor (alpha-NAC related); Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family. (131 aa)
hmgA3-hydroxy-3-methylglutaryl-coenzyme a reductase (hmg-coa reductase); Belongs to the HMG-CoA reductase family. (408 aa)
rplX50S ribosomal protein LX. (58 aa)
rpl31e50S ribosomal protein L31E; Belongs to the eukaryotic ribosomal protein eL31 family. (91 aa)
rps19e30S ribosomal protein S19E; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (146 aa)
RCIX107Predicted ATPase (RecA family); Similarities with kaiC (circadian clock regulatory protein kinase). (491 aa)
top6B-2Type II DNA topoisomerase VI, subunit B; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. (556 aa)
top6A-2Type II DNA topoisomerase VI, subunit A. (375 aa)
mpgPutative 3-methyladenine DNA glycosylase; Belongs to the DNA glycosylase MPG family. (200 aa)
RCIX1108Conserved hypothetical protein. (167 aa)
cdc6-1Cell division cycle protein 6; Involved in regulation of DNA replication. (415 aa)
cdc48-3Cell division cycle protein 48. (758 aa)
RCIX115Conserved hypothetical protein; Similarities with kaiC (circadian clock regulatory protein kinase) and Rad55 (RecA-superfamily ATPase implicated in signal transduction). (231 aa)
RCIX117Conserved hypothetical protein; Similarities with kaiC (circadian clock regulatory protein kinase) and Rad55 (RecA-superfamily ATPase implicated in signal transduction). (289 aa)
polXDNA-directed DNA polymerase X. (574 aa)
RCIX1210RNase L inhibitor. (590 aa)
xthAExodeoxyribonuclease III; Gene synonym: exoA. (257 aa)
tbpETATA-box binding protein E; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (188 aa)
RCIX1257Conserved hypothetical protein. (138 aa)
RCIX1263Putative type III restriction-modification system, restriction subunit. (792 aa)
RCIX1272Conserved hypothetical protein. (336 aa)
RCIX13104Fe-4S ferredoxin-domain protein. (385 aa)
RCIX1333Conserved hypothetical protein. (250 aa)
RCIX1335Predicted regulator of chromosome condensation. (451 aa)
RCIX1340Putative metallo-beta-lactamase. (247 aa)
RCIX1428Conserved hypothetical protein. (285 aa)
rpl40e50S ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family. (48 aa)
RCIX1585Predicted regulator of chromosome condensation. (447 aa)
RCIX1603Predicted SAM-dependent methyltransferase. (174 aa)
nifH-1Nitrogenase iron protein (nitrogenase reductase); The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein. (274 aa)
RCIX1654Glutaredoxin-like protein; Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro. (79 aa)
hpyA1Putative archaeal histone A1 (H4 family). (70 aa)
RCIX1761Predicted regulator of chromosome condensation. (439 aa)
recQATP-dependent DNA helicase. (605 aa)
rfcLReplication factor C, large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. (553 aa)
cdc6-2Cell division cycle protein 6; Involved in regulation of DNA replication. (375 aa)
RCIX1862Conserved GTP-binding protein (Ras family). (211 aa)
RCIX1863Conserved hypothetical CBS domain protein. (193 aa)
RCIX1864Conserved hypothetical CBS domain protein. (260 aa)
RCIX1866Conserved hypothetical CBS domain protein. (324 aa)
RCIX1867Conserved hypothetical CBS domain protein. (283 aa)
RCIX1868Conserved hypothetical CBS domain protein. (259 aa)
RCIX1934Conserved hypothetical protein. (493 aa)
RCIX1966Conserved hypothetical protein. (298 aa)
rpl10e-250S ribosomal protein L10E; Belongs to the universal ribosomal protein uL16 family. (172 aa)
nifH-2Nitrogenase iron protein (nitrogenase reductase). (272 aa)
cbiX-1Putative sirohydrochlorin cobaltochelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni- sirohydrochlorin. (133 aa)
RCIX2018Conserved hypothetical protein. (121 aa)
RCIX209Conserved hypothetical protein. (193 aa)
RCIX210Conserved hypothetical protein. (384 aa)
RCIX2110Conserved hypothetical protein. (79 aa)
rpl15e50S ribosomal protein L15E; Belongs to the eukaryotic ribosomal protein eL15 family. (196 aa)
RCIX2122Conserved hypothetical protein. (231 aa)
rpl37ae50S ribosomal protein L37AE; Binds to the 23S rRNA. (96 aa)
RCIX214Predicted SAM-dependent methyltransferase. (460 aa)
kptAPutative RNA 2'-phosphotransferase; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase. (211 aa)
RCIX2178Predicted SAM-dependent methyltransferase. (239 aa)
RCIX2198Hypothetical protein. (876 aa)
RCIX2215Conserved hypothetical protein. (250 aa)
rbcLRibulose 1,5-bisphosphate carboxylase (RuBisCO),large subunit. (412 aa)
truAtRNA pseudouridine synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. (266 aa)
RCIX2249ATPase (AAA superfamily); Belongs to the AAA ATPase family. (429 aa)
smcChromosome segregation/partition protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1173 aa)
eif2b1Translation initiation factor 2B, subunit 1; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. (342 aa)
rps3ae30S ribosomal protein S3AE; Belongs to the eukaryotic ribosomal protein eS1 family. (225 aa)
repDPutative ATP-dependent DNA-repair helicase. (721 aa)
tfsArchaeal transcription factor S; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (106 aa)
priBDNA primase, large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. (366 aa)
topA-1DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (767 aa)
RCIX2327Conserved hypothetical protein. (317 aa)
hmfAArchaeal histone A. (69 aa)
pus10Conserved hypothetical protein; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. (440 aa)
rpl21e50S ribosomal protein L21E; Belongs to the eukaryotic ribosomal protein eL21 family. (99 aa)
RCIX2394Putative ATP-dependent helicase. (864 aa)
ugdUDP-glucose 6-dehydrogenase. (429 aa)
RCIX2412Hypothetical protein. (350 aa)
gatB-1glutamyl-tRNA(Gln) amidotransferase, subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (485 aa)
topA-2DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (728 aa)
RCIX2438Predicted SAM-dependent methyltransferase. (251 aa)
RCIX2456Putative transcription factor. (166 aa)
adk-1Putative adenylate kinase; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. (168 aa)
albADNA/RNA-binding protein Alba; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes; Belongs to the histone-like Alba family. (96 aa)
RCIX2472Predicted redox-active protein (CxxC motives). (153 aa)
RCIX2491Hypothetical protein. (317 aa)
RCIX2497Conserved hypothetical protein. (225 aa)
RCIX2501Predicted endonuclease/exonuclease. (294 aa)
RCIX2525Conserved hypothetical protein. (1055 aa)
dcmC-5 cytosine-specific DNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (419 aa)
RCIX2536Putative DNA glycosylase. (212 aa)
rpl3p50S ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (337 aa)
rpl4p50S ribosomal protein L4P; Forms part of the polypeptide exit tunnel. (253 aa)
rpl23p50S ribosomal protein L23P; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (82 aa)
rpl2p50S ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (238 aa)
rps19p30S ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (140 aa)
rpl22p50S ribosomal protein L22P; This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (153 aa)
rps3p30S ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (279 aa)
rpl29p50S ribosomal protein L29P; Belongs to the universal ribosomal protein uL29 family. (71 aa)
rps17p30S ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (111 aa)
rpl14p50S ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (132 aa)
rpl24p50S ribosomal protein L24P; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (123 aa)
rps4e30S ribosomal protein S4E; Belongs to the eukaryotic ribosomal protein eS4 family. (234 aa)
rpl5p50S ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (170 aa)
rps14p30S ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles. (50 aa)
rps8p30S ribosomal protein S8P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa)
rpl6p50S ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (177 aa)
rpl32ePutative 50S ribosomal protein L32E. (221 aa)
rpl19e50S ribosomal protein L19E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (152 aa)
rpl18p50S ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (188 aa)
rps5p30S ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy. (212 aa)
rpl30p50S ribosomal protein L30P. (153 aa)
rpl15p50S ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (146 aa)
truBPutative tRNA pseudouridine synthase B; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. (328 aa)
rps13pPutative 30S ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (224 aa)
rps4p30S ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (205 aa)
rps11p30S ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (132 aa)
rps8e30S ribosomal protein S8E. (125 aa)
RCIX2705Putative ATPase (AAA superfamily). (292 aa)
trm1N(2),N(2)-dimethylguanosine tRNA methyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (365 aa)
RCIX2726Conserved hypothetical protein. (644 aa)
polB-3Putative DNA-directed DNA polymerase B. (770 aa)
RCIX28Putative hydrolase (haloacid dehalogenase superfamily). (243 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. (481 aa)
RCIX292Conserved hypothetical protein. (198 aa)
RCIX293Conserved hypothetical protein. (401 aa)
RCIX305dCMP deaminase. (167 aa)
ptpSPutative 6-pyruvoyl-tetrahydropterin synthase. (112 aa)
RCIX360Thioredoxin-like protein. (169 aa)
hmgA-23-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family. (428 aa)
RCIX407Conserved hypothetical protein. (307 aa)
RCIX455Conserved hypothetical protein. (241 aa)
RCIX492Predicted regulator of chromosome condensation. (441 aa)
hel308Putative ski2-type helicase; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks. (740 aa)
gyrAType II DNA topoisomerase II (gyrase), subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an [...] (826 aa)
RCIX580Putative methyltransferase (UbiE/COQ5 family). (220 aa)
gyrBType II DNA topoisomerase II (gyrase), subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an [...] (635 aa)
fenFlap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...] (340 aa)
rps27ae30S ribosomal protein S27AE; Belongs to the eukaryotic ribosomal protein eS31 family. (44 aa)
RCIX628Putative SAM-dependent methyltransferase. (228 aa)
cdc48-1Putative cell division cycle protein 48. (942 aa)
cdc48-2Cell division cycle protein 48. (743 aa)
rnzRNase Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (304 aa)
RCIX72Conserved hypothetical protein. (279 aa)
rps17e30s ribosomal protein S17E; Belongs to the eukaryotic ribosomal protein eS17 family. (65 aa)
pycAPutative pyruvate carboxylase, subunit A. (722 aa)
ppiBPeptidyl-prolyl cis-trans isomerase B (cyclophilin type). (142 aa)
RCIX759Hypothetical protein. (189 aa)
RCIX807Predicted regulator of chromosome condensation; Similar to RCIX819. (445 aa)
RCIX819Predicted regulator of chromosome condensation; Similar to RCIX807. (478 aa)
ubiEUbiquinone/menaquinone biosynthesis methyltransferase. (270 aa)
RCIX894Putative GTP-binding protein (Ras GTPase family). (174 aa)
RCIX900Hypothetical protein. (162 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (427 aa)
cysGuroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. (248 aa)
lysMPutative methyltransferase. (201 aa)
RCIX924Putative hydrolase (HAD superfamily). (245 aa)
RCIX925Putative hydrolase (HAD superfamily). (258 aa)
RCIX927Predicted endonuclease III. (307 aa)
RCIX977Putative metal-dependent phosphohydrolase (HD superfamily). (431 aa)
cbiX-2Putative sirohydrochlorin cobaltochelatase. (119 aa)
RRC12Conserved hypothetical protein. (220 aa)
pdhBPyruvate dehydrogenase complex E1, transketolase beta subunit. (325 aa)
pdhAPyruvate dehydrogenase complex E1, transketolase alpha subunit. (359 aa)
endAtRNA-splicing endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp. (353 aa)
RRC248Hypothetical protein. (425 aa)
RRC278Hypothetical protein. (453 aa)
RRC290Hypothetical protein. (280 aa)
RRC295Predicted ferredoxin:thioredoxin reductase subunit. (115 aa)
nfoPutative endonuclease IV. (265 aa)
RRC355Conserved hypothetical protein. (339 aa)
polB-4DNA-directed DNA polymerase B. (798 aa)
RRC405Conserved hypothetical protein. (376 aa)
RRC430ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. (451 aa)
ubiXPutative aromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (185 aa)
RRC451Putative metal-dependent phosphohydrolase (HD superfamily). (396 aa)
RRC454Conserved hypothetical protein. (173 aa)
RRC49Putative iron-containing alcohol dehydrogenase. (388 aa)
RRC51Hypothetical protein. (396 aa)
RRC53Predicted cobalamin biosynthesis protein (CbiX-like). (305 aa)
aat-4Putative aspartate aminotransferase. (381 aa)
RRC63Predicted endonuclease III. (243 aa)
RRC95Predicted DNA repair exonuclease (Rad32/Mre11-like). (471 aa)
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
Server load: low (16%) [HD]