STRINGSTRING
LRC101 LRC101 top6A-1 top6A-1 rps28e rps28e rpl12p rpl12p rpl10e rpl10e rpl44e rpl44e priA priA LRC304 LRC304 rpl30e rpl30e rps10p rps10p flpA flpA LRC386 LRC386 rfcS rfcS LRC4 LRC4 rps2p rps2p rps9p rps9p rps6e rps6e cyaB cyaB LRC445 LRC445 dnaJ dnaJ LRC482 LRC482 LRC525 LRC525 RCIX1018 RCIX1018 rpl31e rpl31e rps19e rps19e RCIX1066 RCIX1066 top6A-2 top6A-2 RCIX1090 RCIX1090 cdc6-1 cdc6-1 RCIX1138 RCIX1138 RCIX1189 RCIX1189 RCIX1276 RCIX1276 rpl40e rpl40e RCIX1447 RCIX1447 RCIX1487 RCIX1487 hpyA1 hpyA1 recQ recQ RCIX1785 RCIX1785 RCIX1790 RCIX1790 rfcL rfcL RCIX1845 RCIX1845 cdc6-2 cdc6-2 RCIX1965 RCIX1965 RCIX1966 RCIX1966 RCIX1984 RCIX1984 RCIX1999 RCIX1999 RCIX2110 RCIX2110 rpl15e rpl15e rpl37ae rpl37ae RCIX2182 RCIX2182 rbcL rbcL RCIX2239 RCIX2239 rps3ae rps3ae priB priB hmfA hmfA zim zim rpl21e rpl21e RCIX2401 RCIX2401 RCIX2402 RCIX2402 RCIX2412 RCIX2412 albA albA RCIX2503 RCIX2503 RCIX2539 RCIX2539 rps19p rps19p rps3p rps3p rpl29p rpl29p rps17p rps17p rps4e rps4e rpl6p rpl6p rpl32e rpl32e rpl19e rpl19e rpl18p rpl18p rps5p rps5p truB truB rps4p rps4p RCIX2597 RCIX2597 RCIX2617 RCIX2617 RCIX2663 RCIX2663 RCIX2705 RCIX2705 dnaG dnaG RCIX285 RCIX285 RCIX305 RCIX305 RCIX650 RCIX650 RCIX676 RCIX676 rps17e rps17e RCIX848 RCIX848 RCIX90 RCIX90 RCIX927 RCIX927 RCIX940 RCIX940 RCIX977 RCIX977 RRC149 RRC149 RRC290 RRC290 RRC451 RRC451 RRC63 RRC63 pdxS pdxS RRC95 RRC95 RRC96 RRC96
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LRC101Predicted iron-molybdenum cofactor biosynthesis protein. (119 aa)
top6A-1Type II DNA topoisomerase VI, subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. (366 aa)
rps28e30S ribosomal protein S28E; Belongs to the eukaryotic ribosomal protein eS28 family. (70 aa)
rpl12pPutative 50S ribosomal protein L12P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (103 aa)
rpl10e50S ribosomal protein L10E; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (304 aa)
rpl44e50S ribosomal protein L44E; Binds to the 23S rRNA. (93 aa)
priADNA primase, small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...] (400 aa)
LRC304Putative transcription regulator (TrmB family); Identical to orf15 of fosmid clone 3D10mr4. (264 aa)
rpl30e50S ribosomal protein L30E; Belongs to the eukaryotic ribosomal protein eL30 family. (101 aa)
rps10p30S ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (104 aa)
flpAFibrillarin-like pre-rRNA processing protein; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. (220 aa)
LRC386Nop56-like pre-mRNA processing protein. (297 aa)
rfcSReplication factor C (clamp loader), small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily. (322 aa)
LRC4Conserved hypothetical protein. (232 aa)
rps2p30S ribosomal protein S2P; Belongs to the universal ribosomal protein uS2 family. (207 aa)
rps9p30S ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family. (136 aa)
rps6e30S ribosomal protein S6E; Belongs to the eukaryotic ribosomal protein eS6 family. (142 aa)
cyaBAdenylate cyclase. (176 aa)
LRC445Putative chaperonin (DnaJ family), N-terminal fragment. (175 aa)
dnaJChaperonin Hsp40; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK an [...] (380 aa)
LRC482Conserved hypothetical protein. (225 aa)
LRC525Conserved hypothetical protein. (124 aa)
RCIX1018Conserved hypothetical GTP-binding protein. (355 aa)
rpl31e50S ribosomal protein L31E; Belongs to the eukaryotic ribosomal protein eL31 family. (91 aa)
rps19e30S ribosomal protein S19E; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (146 aa)
RCIX1066Hypothetical protein. (426 aa)
top6A-2Type II DNA topoisomerase VI, subunit A. (375 aa)
RCIX1090Predicted Zn-finger protein interacting with DnaK (DnaJ-like). (494 aa)
cdc6-1Cell division cycle protein 6; Involved in regulation of DNA replication. (415 aa)
RCIX1138Predicted protein interacting with DnaK (DnaJ-like). (242 aa)
RCIX1189Putative transcription regulator (TrmB family); Similar to orf15 of fosmid clone 3D10mr4. (274 aa)
RCIX1276Putative phosphoesterase. (495 aa)
rpl40e50S ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family. (48 aa)
RCIX1447Hypothetical protein. (95 aa)
RCIX1487Predicted methanol dehydrogenase regulator MoxR-like ATPase. (312 aa)
hpyA1Putative archaeal histone A1 (H4 family). (70 aa)
recQATP-dependent DNA helicase. (605 aa)
RCIX1785Putative transcription regulator (TrmB family). (273 aa)
RCIX1790Transcription regulator (TrmB family). (260 aa)
rfcLReplication factor C, large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. (553 aa)
RCIX1845Conserved hypothetical protein. (122 aa)
cdc6-2Cell division cycle protein 6; Involved in regulation of DNA replication. (375 aa)
RCIX1965Conserved hypothetical protein. (225 aa)
RCIX1966Conserved hypothetical protein. (298 aa)
RCIX1984Putative glycosyltransferase (family 2). (427 aa)
RCIX1999Hypothetical protein. (1632 aa)
RCIX2110Conserved hypothetical protein. (79 aa)
rpl15e50S ribosomal protein L15E; Belongs to the eukaryotic ribosomal protein eL15 family. (196 aa)
rpl37ae50S ribosomal protein L37AE; Binds to the 23S rRNA. (96 aa)
RCIX2182Hypothetical phage-like protein. (867 aa)
rbcLRibulose 1,5-bisphosphate carboxylase (RuBisCO),large subunit. (412 aa)
RCIX2239Hypothetical protein. (189 aa)
rps3ae30S ribosomal protein S3AE; Belongs to the eukaryotic ribosomal protein eS1 family. (225 aa)
priBDNA primase, large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. (366 aa)
hmfAArchaeal histone A. (69 aa)
zimN-4 cytosine-specific methyltransferase. (347 aa)
rpl21e50S ribosomal protein L21E; Belongs to the eukaryotic ribosomal protein eL21 family. (99 aa)
RCIX2401Conserved hypothetical protein. (119 aa)
RCIX2402Conserved hypothetical protein. (122 aa)
RCIX2412Hypothetical protein. (350 aa)
albADNA/RNA-binding protein Alba; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes; Belongs to the histone-like Alba family. (96 aa)
RCIX2503Hypothetical protein. (234 aa)
RCIX2539Hypothetical protein. (93 aa)
rps19p30S ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (140 aa)
rps3p30S ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (279 aa)
rpl29p50S ribosomal protein L29P; Belongs to the universal ribosomal protein uL29 family. (71 aa)
rps17p30S ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (111 aa)
rps4e30S ribosomal protein S4E; Belongs to the eukaryotic ribosomal protein eS4 family. (234 aa)
rpl6p50S ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (177 aa)
rpl32ePutative 50S ribosomal protein L32E. (221 aa)
rpl19e50S ribosomal protein L19E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (152 aa)
rpl18p50S ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (188 aa)
rps5p30S ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy. (212 aa)
truBPutative tRNA pseudouridine synthase B; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. (328 aa)
rps4p30S ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (205 aa)
RCIX2597Hypothetical protein. (292 aa)
RCIX2617Putative N6 adenine-specific DNA methyltransferase. (307 aa)
RCIX2663Predicted ATPase (chaperonin ClpA/B family). (475 aa)
RCIX2705Putative ATPase (AAA superfamily). (292 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. (481 aa)
RCIX285Conserved hypothetical protein; Belongs to the UPF0292 family. (138 aa)
RCIX305dCMP deaminase. (167 aa)
RCIX650Lipase. (325 aa)
RCIX676Conserved hypothetical protein. (322 aa)
rps17e30s ribosomal protein S17E; Belongs to the eukaryotic ribosomal protein eS17 family. (65 aa)
RCIX848Conserved hypothetical protein. (104 aa)
RCIX90Hypothetical protein. (581 aa)
RCIX927Predicted endonuclease III. (307 aa)
RCIX940Hypothetical protein. (267 aa)
RCIX977Putative metal-dependent phosphohydrolase (HD superfamily). (431 aa)
RRC149Hypothetical protein. (265 aa)
RRC290Hypothetical protein. (280 aa)
RRC451Putative metal-dependent phosphohydrolase (HD superfamily). (396 aa)
RRC63Predicted endonuclease III. (243 aa)
pdxSPutative pyridoxal biosynthesis lyase; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (298 aa)
RRC95Predicted DNA repair exonuclease (Rad32/Mre11-like). (471 aa)
RRC96Predicted DNA repair ATPase (Rad50-like). (782 aa)
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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