(20 nodes) Purine metabolism network (Thalassiosira pseudonana)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	APT2	Probable adenine phosphoribosyltransferase. (145 aa)
	B8BQC8_THAPS	Nucleotide diphosphatase. (198 aa)
	B8BQP3_THAPS	3',5'-cyclic nucleotide phosphodiesterase; Belongs to the cyclic nucleotide phosphodiesterase family. (303 aa)
	B8BRB2_THAPS	Phosphodiesterase. (558 aa)
	B8BRC9_THAPS	Uncharacterized protein. (324 aa)
	B8BST1_THAPS	3',5'-cyclic amp phosphodiesterase; Belongs to the cyclic nucleotide phosphodiesterase family. (321 aa)
	B8BTZ3_THAPS	ADK_lid domain-containing protein; Belongs to the adenylate kinase family. (227 aa)
	B8BX07_THAPS	3',5'-cyclic amp phosphodiesterase; Belongs to the cyclic nucleotide phosphodiesterase family. (285 aa)
	B8BXI8_THAPS	Adenylate kinase; Belongs to the adenylate kinase family. (222 aa)
	B8BYJ8_THAPS	Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity; Belongs to the adenylate kinase family. AK6 subfamily. (184 aa)
	B8BZA9_THAPS	Probable amp deaminase. (530 aa)
	B8BZC2_THAPS	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (528 aa)
	B8C1B3_THAPS	GMP synthase. (539 aa)
	B8C496_THAPS	3',5'-cyclic amp phosphodiesterase; Belongs to the cyclic nucleotide phosphodiesterase family. (332 aa)
	B8C545_THAPS	ADK_lid domain-containing protein; Belongs to the adenylate kinase family. (167 aa)
	AK2	Adenosine kinase. (337 aa)
	B8CAV8_THAPS	Guanylate cyclase. (217 aa)
	B8CBJ0_THAPS	Uncharacterized protein; Belongs to the adenylate kinase family. (285 aa)
	B8CC71_THAPS	Uncharacterized protein; Belongs to the adenylate kinase family. (181 aa)
	B8CDS3_THAPS	3',5'-cyclic nucleotide phosphodiesterase; Belongs to the cyclic nucleotide phosphodiesterase family. (345 aa)

Your Current Organism:

Thalassiosira pseudonana

NCBI taxonomy Id: 35128
Other names: T. pseudonana

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AK2	APT2	B8C871	B5YNT3	Adenosine kinase.	Probable adenine phosphoribosyltransferase.	0.980
AK2	B8BQP3_THAPS	B8C871	B8BQP3	Adenosine kinase.	3',5'-cyclic nucleotide phosphodiesterase; Belongs to the cyclic nucleotide phosphodiesterase family.	0.907
AK2	B8BRB2_THAPS	B8C871	B8BRB2	Adenosine kinase.	Phosphodiesterase.	0.902
AK2	B8BST1_THAPS	B8C871	B8BST1	Adenosine kinase.	3',5'-cyclic amp phosphodiesterase; Belongs to the cyclic nucleotide phosphodiesterase family.	0.907
AK2	B8BTZ3_THAPS	B8C871	B8BTZ3	Adenosine kinase.	ADK_lid domain-containing protein; Belongs to the adenylate kinase family.	0.941
AK2	B8BX07_THAPS	B8C871	B8BX07	Adenosine kinase.	3',5'-cyclic amp phosphodiesterase; Belongs to the cyclic nucleotide phosphodiesterase family.	0.907
AK2	B8BXI8_THAPS	B8C871	B8BXI8	Adenosine kinase.	Adenylate kinase; Belongs to the adenylate kinase family.	0.941
AK2	B8BYJ8_THAPS	B8C871	B8BYJ8	Adenosine kinase.	Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity; Belongs to the adenylate kinase family. AK6 subfamily.	0.908
AK2	B8BZA9_THAPS	B8C871	B8BZA9	Adenosine kinase.	Probable amp deaminase.	0.954
AK2	B8BZC2_THAPS	B8C871	B8BZC2	Adenosine kinase.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.490
AK2	B8C1B3_THAPS	B8C871	B8C1B3	Adenosine kinase.	GMP synthase.	0.423
AK2	B8C496_THAPS	B8C871	B8C496	Adenosine kinase.	3',5'-cyclic amp phosphodiesterase; Belongs to the cyclic nucleotide phosphodiesterase family.	0.907
AK2	B8C545_THAPS	B8C871	B8C545	Adenosine kinase.	ADK_lid domain-containing protein; Belongs to the adenylate kinase family.	0.941
AK2	B8CBJ0_THAPS	B8C871	B8CBJ0	Adenosine kinase.	Uncharacterized protein; Belongs to the adenylate kinase family.	0.941
AK2	B8CC71_THAPS	B8C871	B8CC71	Adenosine kinase.	Uncharacterized protein; Belongs to the adenylate kinase family.	0.913
AK2	B8CDS3_THAPS	B8C871	B8CDS3	Adenosine kinase.	3',5'-cyclic nucleotide phosphodiesterase; Belongs to the cyclic nucleotide phosphodiesterase family.	0.902
APT2	AK2	B5YNT3	B8C871	Probable adenine phosphoribosyltransferase.	Adenosine kinase.	0.980
APT2	B8BQC8_THAPS	B5YNT3	B8BQC8	Probable adenine phosphoribosyltransferase.	Nucleotide diphosphatase.	0.921
APT2	B8BQP3_THAPS	B5YNT3	B8BQP3	Probable adenine phosphoribosyltransferase.	3',5'-cyclic nucleotide phosphodiesterase; Belongs to the cyclic nucleotide phosphodiesterase family.	0.900
APT2	B8BRB2_THAPS	B5YNT3	B8BRB2	Probable adenine phosphoribosyltransferase.	Phosphodiesterase.	0.907