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THAPS_41425 THAPS_41425 B8BQB4_THAPS B8BQB4_THAPS MDH1 MDH1 AAT2 AAT2 IDH1 IDH1 SCS1 SCS1 B8BS58_THAPS B8BS58_THAPS THAPSDRAFT_899 THAPSDRAFT_899 B8BSX2_THAPS B8BSX2_THAPS B8BTA3_THAPS B8BTA3_THAPS PDK1_1 PDK1_1 LAT1_2 LAT1_2 LAT2 LAT2 B8BUT0_THAPS B8BUT0_THAPS B8BV33_THAPS B8BV33_THAPS PDHA1 PDHA1 B8BWY9_THAPS B8BWY9_THAPS B8BX10_THAPS B8BX10_THAPS B8BX11_THAPS B8BX11_THAPS B8BX37_THAPS B8BX37_THAPS B8BXD4_THAPS B8BXD4_THAPS SDH1 SDH1 B8BYY9_THAPS B8BYY9_THAPS MDH2 MDH2 SCS2 SCS2 FUM1 FUM1 PPC2 PPC2 MAO1 MAO1 PDK1_2 PDK1_2 ACAS2 ACAS2 SDH SDH THAPSDRAFT_547 THAPSDRAFT_547 B8C489_THAPS B8C489_THAPS B8C5P9_THAPS B8C5P9_THAPS B8C5Q0_THAPS B8C5Q0_THAPS B8C648_THAPS B8C648_THAPS B8C8C2_THAPS B8C8C2_THAPS B8C935_THAPS B8C935_THAPS B8CAI1_THAPS B8CAI1_THAPS B8CAK5_THAPS B8CAK5_THAPS B8CBX3_THAPS B8CBX3_THAPS B8CCG5_THAPS B8CCG5_THAPS B8CCT7_THAPS B8CCT7_THAPS B8CDK2_THAPS B8CDK2_THAPS B8CE35_THAPS B8CE35_THAPS B8CE42_THAPS B8CE42_THAPS THAPSDRAFT_795 THAPSDRAFT_795 CSN1 CSN1 B8CEH1_THAPS B8CEH1_THAPS B8CG06_THAPS B8CG06_THAPS LASPO LASPO LPD LPD PDHB1 PDHB1 DLDH2 DLDH2 B8LCZ7_THAPS B8LCZ7_THAPS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
THAPS_41425Cytosolic malate dehydrogenase; Belongs to the LDH/MDH superfamily. (374 aa)
B8BQB4_THAPSProtein-serine/threonine kinase. (417 aa)
MDH1Malate dehydrogenase. (352 aa)
AAT2Aspartate aminotransferase. (416 aa)
IDH1Uncharacterized protein. (662 aa)
SCS1Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (419 aa)
B8BS58_THAPSLipoyl-binding domain-containing protein. (307 aa)
THAPSDRAFT_899Uncharacterized protein. (1175 aa)
B8BSX2_THAPS2-oxoacid_dh domain-containing protein. (218 aa)
B8BTA3_THAPSAlpha-keto acid dehydrogenase. (323 aa)
PDK1_1Protein-serine/threonine kinase. (320 aa)
LAT1_2Dihydrolipoamide s-acetyltransferase. (328 aa)
LAT2Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (508 aa)
B8BUT0_THAPSTransket_pyr domain-containing protein. (814 aa)
B8BV33_THAPSUncharacterized protein. (137 aa)
PDHA1Pyruvate dehydrogenase. (375 aa)
B8BWY9_THAPSUncharacterized protein. (714 aa)
B8BX10_THAPSPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (349 aa)
B8BX11_THAPSE1_dh domain-containing protein. (314 aa)
B8BX37_THAPSEF-hand domain-containing protein. (560 aa)
B8BXD4_THAPSUncharacterized protein. (90 aa)
SDH1Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (240 aa)
B8BYY9_THAPSProbable SOLUBLE pyridine nucleotide transhydrogenase. (466 aa)
MDH2Malate dehydrogenase. (364 aa)
SCS2Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (299 aa)
FUM1Fumarate hydratase. (626 aa)
PPC2Phospoenolpyruvate carboxylase. (843 aa)
MAO1NAD dependent malic enzyme. (559 aa)
PDK1_2Pyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (933 aa)
ACAS2Acetyl-coenzyme A synthetase. (645 aa)
SDHSarcosine dehydrogenase. (895 aa)
THAPSDRAFT_547Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (426 aa)
B8C489_THAPSLipoyl-binding domain-containing protein. (126 aa)
B8C5P9_THAPSPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (318 aa)
B8C5Q0_THAPSE1_dh domain-containing protein. (343 aa)
B8C648_THAPSMalate synthase; Belongs to the malate synthase family. (555 aa)
B8C8C2_THAPSDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (423 aa)
B8C935_THAPSUncharacterized protein. (512 aa)
B8CAI1_THAPSBPL/LPL catalytic domain-containing protein. (141 aa)
B8CAK5_THAPSLipoyl-binding domain-containing protein. (378 aa)
B8CBX3_THAPS2-oxoglutarate dehydrogenase E1 component. (1015 aa)
B8CCG5_THAPSUncharacterized protein. (191 aa)
B8CCT7_THAPSSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (637 aa)
B8CDK2_THAPSPPM-type phosphatase domain-containing protein. (206 aa)
B8CE35_THAPSMercuric reductase. (550 aa)
B8CE42_THAPSPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1155 aa)
THAPSDRAFT_7952-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (337 aa)
CSN1Citrate synthase; Belongs to the citrate synthase family. (473 aa)
B8CEH1_THAPSAcetyl-coa synthetase. (973 aa)
B8CG06_THAPSUncharacterized protein. (373 aa)
LASPOL-aspartate oxidase. (570 aa)
LPDDihydrolipoyl dehydrogenase. (470 aa)
PDHB1Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (336 aa)
DLDH2Uncharacterized protein DLDH2. (498 aa)
B8LCZ7_THAPSPredicted protein. (1236 aa)
Your Current Organism:
Thalassiosira pseudonana
NCBI taxonomy Id: 35128
Other names: T. pseudonana
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