(114 nodes) Mixed, incl. Organic acid catabolic process, and Valine, leucine and isoleucine degradation network (Thalassiosira pseudonana)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rbcS	Ribulose-1,5-bisphosphate carboxylase/oxygenase small subunit. (139 aa)
	rbcL	Ribulose bisphosphate carboxylase large chain; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site. (490 aa)
	rbcL-2	Ribulose bisphosphate carboxylase large chain. (490 aa)
	THAPS_25322	Predicted protein. (633 aa)
	THAPS_25412	Predicted protein. (266 aa)
	THAPS_35523	Isocitrate lyase. (541 aa)
	THAPS_41314	Predicted protein. (273 aa)
	THAPS_35420	Betaine aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (519 aa)
	THAPS_6996	Predicted protein. (249 aa)
	AAT1_2	Aspartate aminotransferase. (416 aa)
	THAPS_23526	Predicted protein. (317 aa)
	THAPS_7230	Predicted protein. (257 aa)
	ACD1	Acyl-coa dehydrogenase. (378 aa)
	THAPS_6667	Predicted protein. (511 aa)
	THAPS_269199	Predicted protein. (244 aa)
	THAPSDRAFT_174	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (436 aa)
	B8BQK1_THAPS	DAO domain-containing protein. (376 aa)
	B8BQT0_THAPS	CMP/dCMP-type deaminase domain-containing protein. (183 aa)
	ADH1	Probable alcohol dehydrogenase. (391 aa)
	B8BSD3_THAPS	VOC domain-containing protein. (157 aa)
	ADH2	Alcohol dehydrogenase. (344 aa)
	THAPSDRAFT_974	MaoC-like domain-containing protein. (410 aa)
	B8BT05_THAPS	Uncharacterized protein. (379 aa)
	B8BTC4_THAPS	Uncharacterized protein. (736 aa)
	CAT2	Carnitine acetyl transferase; Belongs to the carnitine/choline acetyltransferase family. (574 aa)
	ALD3	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (468 aa)
	HDP1	4-hydroxyphenylpyruvate dioxygenase. (418 aa)
	B8BUB3_THAPS	FAA_hydrolase domain-containing protein. (238 aa)
	B8BUC3_THAPS	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (453 aa)
	B8BUI4_THAPS	APH domain-containing protein. (422 aa)
	B8BUS7_THAPS	Hydroxyacylglutathione hydrolase. (262 aa)
	B8BUS8_THAPS	Hydroxyacylglutathione hydrolase. (269 aa)
	B8BUW9_THAPS	DJ-1_PfpI domain-containing protein. (184 aa)
	B8BV12_THAPS	Uncharacterized protein. (307 aa)
	FAO1	Bifunctional fatty acid oxidation enzyme; Belongs to the enoyl-CoA hydratase/isomerase family. (774 aa)
	B8BVI2_THAPS	Glycerate dehydrogenase and hydroxypyruvate reductase-like protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (340 aa)
	SPR1	Sepiapterin reductase. (137 aa)
	OCT1	Probable 3-oxoacid coa-transferase. (481 aa)
	B8BW62_THAPS	CMP/dCMP-type deaminase domain-containing protein. (180 aa)
	PCC1	Propionyl-coa carboxylase. (501 aa)
	B8BWK9_THAPS	PALP domain-containing protein. (412 aa)
	B8BWT1_THAPS	Uncharacterized protein. (339 aa)
	B8BXB2_THAPS	Uncharacterized protein. (164 aa)
	B8BXH2_THAPS	D-lactate dehydrogenase. (705 aa)
	B8BXJ5_THAPS	L-lactate dehydrogenase. (431 aa)
	B8BXN8_THAPS	Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (672 aa)
	B8BYB3_THAPS	Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (472 aa)
	B8BYP0_THAPS	Aldo-keto oxidoreductase. (324 aa)
	B8BYT6_THAPS	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (360 aa)
	B8BYX0_THAPS	Uncharacterized protein. (664 aa)
	ALD1	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (520 aa)
	ACS2_2	Acetyl-coenzyme A synthetase. (731 aa)
	GOX	Glycolate oxidase. (398 aa)
	B8BZV7_THAPS	Fumarylacetoacetase. (488 aa)
	B8BZV8_THAPS	Uncharacterized protein. (220 aa)
	THAPSDRAFT_413	Uncharacterized protein. (318 aa)
	B8C0F9_THAPS	Uncharacterized protein. (424 aa)
	B8C0X0_THAPS	Tyrosine aminotransferase. (561 aa)
	B8C1E8_THAPS	Aminotransferase. (392 aa)
	B8C1S6_THAPS	Uncharacterized protein. (256 aa)
	ECI1	3,2-TRANS-ENOYL-COA isomerase; Belongs to the enoyl-CoA hydratase/isomerase family. (315 aa)
	B8C2B7_THAPS	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (248 aa)
	THAPSDRAFT_460	Aminotransferase. (455 aa)
	B8C2R0_THAPS	Uncharacterized protein. (699 aa)
	B8C2S7_THAPS	Uncharacterized protein. (931 aa)
	KCT1	3-ketoacyl-coa thiolase, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
	B8C4K4_THAPS	ETF domain-containing protein. (343 aa)
	B8C4S8_THAPS	Probable homogentisate 1,2-dioxygenase. (477 aa)
	AHC3	Adenosylhomocysteinase. (481 aa)
	B8C5X2_THAPS	2-Hacid_dh_C domain-containing protein. (102 aa)
	B8C5Y4_THAPS	Uncharacterized protein. (305 aa)
	AAT1_1	Acetyl-coa acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (408 aa)
	B8C623_THAPS	Alcohol dehydrogenase. (368 aa)
	B8C653_THAPS	Uncharacterized protein. (299 aa)
	ACD3	Probable acyl-coa dehydrogenase, short/branched chain specific. (374 aa)
	B8C6F3_THAPS	Uncharacterized protein. (447 aa)
	PCB1	Beta subunit acetyl/propionyl-CoA carboxylase. (498 aa)
	B8C6F5_THAPS	Probable MaoC family protein. (147 aa)
	B8C6Y3_THAPS	MaoC-like domain-containing protein. (143 aa)
	NPS1	Probable naphthoate synthase; Belongs to the enoyl-CoA hydratase/isomerase family. (323 aa)
	B8C7B6_THAPS	FAD-binding PCMH-type domain-containing protein. (366 aa)
	GCD1	Precursor of hydrogenase glutaryl-coa dehydrogenase. (470 aa)
	B8C7R3_THAPS	Uncharacterized protein. (683 aa)
	B8C948_THAPS	Uncharacterized protein. (533 aa)
	B8C9F6_THAPS	Uncharacterized protein. (567 aa)
	B8C9G0_THAPS	Uncharacterized protein. (373 aa)
	B8C9I8_THAPS	Uncharacterized protein. (447 aa)
	B8C9J4_THAPS	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (683 aa)
	B8C9L9_THAPS	FADH-2,4-dienoyl-CoA reductase. (800 aa)
	AOX1_1	Acyl-coa oxidase. (685 aa)
	B8CAS7_THAPS	EF-hand domain-containing protein. (371 aa)
	B8CB58_THAPS	2-Hacid_dh_C domain-containing protein. (249 aa)
	B8CBP3_THAPS	Uncharacterized protein. (81 aa)
	CAT1_2	Carnitine acetyl transferase; Belongs to the carnitine/choline acetyltransferase family. (641 aa)
	B8CBV4_THAPS	Uncharacterized protein. (395 aa)
	B8CCT5_THAPS	Fe-ADH domain-containing protein. (418 aa)
	B8CD64_THAPS	Uncharacterized protein. (503 aa)
	B8CDG7_THAPS	Probable betaine aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (501 aa)
	B8CDU2_THAPS	Aldedh domain-containing protein. (612 aa)
	B8CEV7_THAPS	Fad-linked oxidase. (529 aa)
	B8CF21_THAPS	Catalase-peroxidase. (735 aa)
	B8CFF5_THAPS	FAD-binding PCMH-type domain-containing protein. (1316 aa)
	B8CG93_THAPS	Aspartate aminotransferase. (444 aa)
	B8CGD2_THAPS	Uncharacterized protein. (356 aa)
	KCT2	3-ketoacyl-coa thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (409 aa)
	B8LC04_THAPS	Predicted protein. (406 aa)
	B8LC13_THAPS	Uncharacterized protein. (588 aa)
	B8LC81_THAPS	Predicted protein. (299 aa)
	B8LCZ8_THAPS	Predicted protein. (1291 aa)
	B8LDA6_THAPS	3-hyroxyacyl CoA dehydrogenase. (350 aa)
	B8LDG4_THAPS	Aldedh domain-containing protein. (567 aa)
	B8LDQ6_THAPS	Predicted protein; Belongs to the enoyl-CoA hydratase/isomerase family. (320 aa)
	ACD2	ACYL-COA dehydrogenase. (380 aa)
	PAH1	Simliar to phenylalanine-4-hydroxylase. (395 aa)

Your Current Organism:

Thalassiosira pseudonana

NCBI taxonomy Id: 35128
Other names: T. pseudonana

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AAT1_1	ACD1	B8C5Z6	B5YNW9	Acetyl-coa acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Acyl-coa dehydrogenase.	0.962
AAT1_1	ACD2	B8C5Z6	B8LE08	Acetyl-coa acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	ACYL-COA dehydrogenase.	0.429
AAT1_1	ACD3	B8C5Z6	B8C661	Acetyl-coa acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Probable acyl-coa dehydrogenase, short/branched chain specific.	0.962
AAT1_1	ACS2_2	B8C5Z6	B8BZT4	Acetyl-coa acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-coenzyme A synthetase.	0.959
AAT1_1	ALD3	B8C5Z6	B8BU49	Acetyl-coa acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.518
AAT1_1	AOX1_1	B8C5Z6	B8CA48	Acetyl-coa acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Acyl-coa oxidase.	0.989
AAT1_1	B8BUI4_THAPS	B8C5Z6	B8BUI4	Acetyl-coa acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	APH domain-containing protein.	0.430
AAT1_1	B8BXN8_THAPS	B8C5Z6	B8BXN8	Acetyl-coa acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone.	0.407
AAT1_1	B8BYB3_THAPS	B8C5Z6	B8BYB3	Acetyl-coa acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.928
AAT1_1	B8BYT6_THAPS	B8C5Z6	B8BYT6	Acetyl-coa acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.	0.774
AAT1_1	B8C1S6_THAPS	B8C5Z6	B8C1S6	Acetyl-coa acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein.	0.415
AAT1_1	B8C2B7_THAPS	B8C5Z6	B8C2B7	Acetyl-coa acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.	0.831
AAT1_1	B8C2S7_THAPS	B8C5Z6	B8C2S7	Acetyl-coa acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein.	0.441
AAT1_1	B8C4K4_THAPS	B8C5Z6	B8C4K4	Acetyl-coa acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	ETF domain-containing protein.	0.602
AAT1_1	B8C6F5_THAPS	B8C5Z6	B8C6F5	Acetyl-coa acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Probable MaoC family protein.	0.513
AAT1_1	B8C6Y3_THAPS	B8C5Z6	B8C6Y3	Acetyl-coa acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	MaoC-like domain-containing protein.	0.513
AAT1_1	B8C7R3_THAPS	B8C5Z6	B8C7R3	Acetyl-coa acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein.	0.441
AAT1_1	B8C9I8_THAPS	B8C5Z6	B8C9I8	Acetyl-coa acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein.	0.746
AAT1_1	B8C9J4_THAPS	B8C5Z6	B8C9J4	Acetyl-coa acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.	0.979
AAT1_1	B8LDA6_THAPS	B8C5Z6	B8LDA6	Acetyl-coa acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	3-hyroxyacyl CoA dehydrogenase.	0.993