(8 nodes) Sterol biosynthetic process network (Thalassiosira pseudonana)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B8C1K1_THAPS	Sterol delta7 reductase-like protein. (382 aa)
	B8BS75_THAPS	Mevalonate disphosphate decarboxylase-like protein. (346 aa)
	HMCS1	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (449 aa)
	B8BTM4_THAPS	Uncharacterized protein. (460 aa)
	B8BU66_THAPS	Mevalonate kinase. (315 aa)
	B8BWW2_THAPS	PEROXIDASE_4 domain-containing protein; Belongs to the peroxidase family. (865 aa)
	B8BYG3_THAPS	GHMP_kinases_N domain-containing protein. (744 aa)
	B8C0R4_THAPS	3-hydroxy-3-methylglutaryl coenzyme A reductase. (368 aa)

Your Current Organism:

Thalassiosira pseudonana

NCBI taxonomy Id: 35128
Other names: T. pseudonana

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B8BS75_THAPS	B8BTM4_THAPS	B8BS75	B8BTM4	Mevalonate disphosphate decarboxylase-like protein.	Uncharacterized protein.	0.495
B8BS75_THAPS	B8BU66_THAPS	B8BS75	B8BU66	Mevalonate disphosphate decarboxylase-like protein.	Mevalonate kinase.	0.954
B8BS75_THAPS	B8BWW2_THAPS	B8BS75	B8BWW2	Mevalonate disphosphate decarboxylase-like protein.	PEROXIDASE_4 domain-containing protein; Belongs to the peroxidase family.	0.608
B8BS75_THAPS	B8BYG3_THAPS	B8BS75	B8BYG3	Mevalonate disphosphate decarboxylase-like protein.	GHMP_kinases_N domain-containing protein.	0.963
B8BS75_THAPS	B8C0R4_THAPS	B8BS75	B8C0R4	Mevalonate disphosphate decarboxylase-like protein.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.681
B8BS75_THAPS	B8C1K1_THAPS	B8BS75	B8C1K1	Mevalonate disphosphate decarboxylase-like protein.	Sterol delta7 reductase-like protein.	0.502
B8BS75_THAPS	HMCS1	B8BS75	B8BSY2	Mevalonate disphosphate decarboxylase-like protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.866
B8BTM4_THAPS	B8BS75_THAPS	B8BTM4	B8BS75	Uncharacterized protein.	Mevalonate disphosphate decarboxylase-like protein.	0.495
B8BTM4_THAPS	B8BU66_THAPS	B8BTM4	B8BU66	Uncharacterized protein.	Mevalonate kinase.	0.462
B8BTM4_THAPS	B8BWW2_THAPS	B8BTM4	B8BWW2	Uncharacterized protein.	PEROXIDASE_4 domain-containing protein; Belongs to the peroxidase family.	0.858
B8BTM4_THAPS	B8C0R4_THAPS	B8BTM4	B8C0R4	Uncharacterized protein.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.458
B8BTM4_THAPS	HMCS1	B8BTM4	B8BSY2	Uncharacterized protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.570
B8BU66_THAPS	B8BS75_THAPS	B8BU66	B8BS75	Mevalonate kinase.	Mevalonate disphosphate decarboxylase-like protein.	0.954
B8BU66_THAPS	B8BTM4_THAPS	B8BU66	B8BTM4	Mevalonate kinase.	Uncharacterized protein.	0.462
B8BU66_THAPS	B8BWW2_THAPS	B8BU66	B8BWW2	Mevalonate kinase.	PEROXIDASE_4 domain-containing protein; Belongs to the peroxidase family.	0.548
B8BU66_THAPS	B8BYG3_THAPS	B8BU66	B8BYG3	Mevalonate kinase.	GHMP_kinases_N domain-containing protein.	0.953
B8BU66_THAPS	B8C0R4_THAPS	B8BU66	B8C0R4	Mevalonate kinase.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.967
B8BU66_THAPS	B8C1K1_THAPS	B8BU66	B8C1K1	Mevalonate kinase.	Sterol delta7 reductase-like protein.	0.463
B8BU66_THAPS	HMCS1	B8BU66	B8BSY2	Mevalonate kinase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.723
B8BWW2_THAPS	B8BS75_THAPS	B8BWW2	B8BS75	PEROXIDASE_4 domain-containing protein; Belongs to the peroxidase family.	Mevalonate disphosphate decarboxylase-like protein.	0.608