STRINGSTRING
hisH hisH THAPS_10878 THAPS_10878 APT2 APT2 B8BQ44_THAPS B8BQ44_THAPS B8BQB0_THAPS B8BQB0_THAPS MTS2_1 MTS2_1 B8BQH3_THAPS B8BQH3_THAPS B8C3C7_THAPS B8C3C7_THAPS B8C4E1_THAPS B8C4E1_THAPS B8C565_THAPS B8C565_THAPS PNP1 PNP1 B8CAL4_THAPS B8CAL4_THAPS B8CAM0_THAPS B8CAM0_THAPS B8CDU8_THAPS B8CDU8_THAPS B8LDA3_THAPS B8LDA3_THAPS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hisHImidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. (570 aa)
THAPS_10878Predicted protein. (485 aa)
APT2Probable adenine phosphoribosyltransferase. (145 aa)
B8BQ44_THAPSPyrimidine-nucleoside phosphorylase. (458 aa)
B8BQB0_THAPSQueuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (412 aa)
MTS2_1Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (476 aa)
B8BQH3_THAPSAmidophosphoribosyltransferase. (537 aa)
B8C3C7_THAPSNicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (520 aa)
B8C4E1_THAPSATP phosphoribosyltransferase. (291 aa)
B8C565_THAPSXanthine phosphoribosyltransferase. (260 aa)
PNP1Probable purine-nucleoside phosphorylase. (241 aa)
B8CAL4_THAPSNicotinate-nucleotide pyrophosphorylase. (291 aa)
B8CAM0_THAPSQueuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (418 aa)
B8CDU8_THAPSUncharacterized protein. (452 aa)
B8LDA3_THAPSPredicted protein. (544 aa)
Your Current Organism:
Thalassiosira pseudonana
NCBI taxonomy Id: 35128
Other names: T. pseudonana
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