(61 nodes) Sulfur compound biosynthetic process network (Thalassiosira pseudonana)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B8BVD1_THAPS	Uncharacterized protein. (2251 aa)
	PDHA1	Pyruvate dehydrogenase. (375 aa)
	B8BVS6_THAPS	Methylenetetrahydrofolate reductase. (383 aa)
	B8BWX4_THAPS	Uncharacterized protein. (957 aa)
	B8BX10_THAPS	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (349 aa)
	B8LEV4_THAPS	Thiamine biosynthesis protein. (269 aa)
	B8LE49_THAPS	Glutamate-cysteine ligase. (680 aa)
	B8LE37_THAPS	Predicted protein. (120 aa)
	B8LD59_THAPS	PALP domain-containing protein. (351 aa)
	PDHB1	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (336 aa)
	B8CGH7_THAPS	Uncharacterized protein. (994 aa)
	B8CG57_THAPS	Uncharacterized protein. (487 aa)
	CBL1	Cystathionine beta-lyase. (381 aa)
	B8CCB2_THAPS	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (205 aa)
	B8CBW8_THAPS	ATP sulfurylase. (968 aa)
	MHMT1	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1251 aa)
	B8C9U6_THAPS	Methylthioadenosine/S-adenosyl homocysteine nucleosidase. (249 aa)
	CGL1	Dubious cystathionine gamma-lyase. (456 aa)
	THI1	Thiamin biosynthesis protein. (636 aa)
	GSHS	Glutathione synthetase. (533 aa)
	B8C6V8_THAPS	Homoserine dehydrogenase. (433 aa)
	B8C6J0_THAPS	Aldolase_II domain-containing protein. (529 aa)
	B8C6A7_THAPS	Glutamate-cysteine ligase. (636 aa)
	B8C5V3_THAPS	Biotin synthase, BioB. (330 aa)
	B8C5Q0_THAPS	E1_dh domain-containing protein. (343 aa)
	B8C5P9_THAPS	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (318 aa)
	B8C574_THAPS	ATP-grasp domain-containing protein. (444 aa)
	B8C489_THAPS	Lipoyl-binding domain-containing protein. (126 aa)
	THAPSDRAFT_547	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (426 aa)
	B8C466_THAPS	Probable thiamin biosynthetic enzyme. (265 aa)
	B8C465_THAPS	Thiaminephosphate pyrophosphorylase thiamine phosphate synthase. (193 aa)
	ASK1	Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. (204 aa)
	B8C3L8_THAPS	Uncharacterized protein. (511 aa)
	B8C2Y3_THAPS	Uncharacterized protein. (462 aa)
	B8C0Y8_THAPS	TENA_THI-4 domain-containing protein. (155 aa)
	B8BYX2_THAPS	ATP-grasp domain-containing protein. (567 aa)
	ASDH	Aspartate-semialdehyde dehydrogenase. (345 aa)
	AMS2	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (450 aa)
	AMS1	Probable S-adenosylmethionine synthetase. (465 aa)
	B8BX11_THAPS	E1_dh domain-containing protein. (314 aa)
	MTNA_THAPS	Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (373 aa)
	thiG	Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (269 aa)
	THAPS_35690	Predicted protein. (277 aa)
	ACC	Acetyl-coa carboxylase. (2088 aa)
	THAPS_6805	Predicted protein. (723 aa)
	THAPS_23407	Predicted protein. (563 aa)
	THAPS_29008	Bifunctional aspartokinase/homoserine dehydrogenase. (936 aa)
	B8BQ31_THAPS	Lipoic acid synthetase. (310 aa)
	CYS2	Cysteine synthase. (355 aa)
	CYS3	Cysteine synthase. (311 aa)
	B8BQL7_THAPS	Uncharacterized protein. (409 aa)
	B8BRT9_THAPS	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (574 aa)
	B8BSX2_THAPS	2-oxoacid_dh domain-containing protein. (218 aa)
	B8BTB6_THAPS	Lipoic acid synthetase. (374 aa)
	LAT1_2	Dihydrolipoamide s-acetyltransferase. (328 aa)
	B8BUL0_THAPS	Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (365 aa)
	B8BUL7_THAPS	Uncharacterized protein. (563 aa)
	LAT2	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (508 aa)
	B8BUU6_THAPS	APH domain-containing protein. (395 aa)
	B8BV33_THAPS	Uncharacterized protein. (137 aa)
	B8BV89_THAPS	DRTGG domain-containing protein. (423 aa)

Your Current Organism:

Thalassiosira pseudonana

NCBI taxonomy Id: 35128
Other names: T. pseudonana

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACC	B8BUL7_THAPS	B5YMF5	B8BUL7	Acetyl-coa carboxylase.	Uncharacterized protein.	0.923
ACC	B8BVD1_THAPS	B5YMF5	B8BVD1	Acetyl-coa carboxylase.	Uncharacterized protein.	0.909
ACC	LAT1_2	B5YMF5	B8BTR7	Acetyl-coa carboxylase.	Dihydrolipoamide s-acetyltransferase.	0.902
ACC	LAT2	B5YMF5	B8BUM6	Acetyl-coa carboxylase.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.902
ACC	THAPSDRAFT_547	B5YMF5	B8C488	Acetyl-coa carboxylase.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.903
AMS1	AMS2	B8BY55	B8BY56	Probable S-adenosylmethionine synthetase.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	0.903
AMS1	ASDH	B8BY55	B8BYC9	Probable S-adenosylmethionine synthetase.	Aspartate-semialdehyde dehydrogenase.	0.525
AMS1	B8BQL7_THAPS	B8BY55	B8BQL7	Probable S-adenosylmethionine synthetase.	Uncharacterized protein.	0.414
AMS1	B8BRT9_THAPS	B8BY55	B8BRT9	Probable S-adenosylmethionine synthetase.	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.627
AMS1	B8BVS6_THAPS	B8BY55	B8BVS6	Probable S-adenosylmethionine synthetase.	Methylenetetrahydrofolate reductase.	0.627
AMS1	B8C2Y3_THAPS	B8BY55	B8C2Y3	Probable S-adenosylmethionine synthetase.	Uncharacterized protein.	0.627
AMS1	B8C5V3_THAPS	B8BY55	B8C5V3	Probable S-adenosylmethionine synthetase.	Biotin synthase, BioB.	0.480
AMS1	B8C6J0_THAPS	B8BY55	B8C6J0	Probable S-adenosylmethionine synthetase.	Aldolase_II domain-containing protein.	0.609
AMS1	MHMT1	B8BY55	B8C9X1	Probable S-adenosylmethionine synthetase.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.950
AMS2	AMS1	B8BY56	B8BY55	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	Probable S-adenosylmethionine synthetase.	0.903
AMS2	ASDH	B8BY56	B8BYC9	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	Aspartate-semialdehyde dehydrogenase.	0.524
AMS2	B8BQL7_THAPS	B8BY56	B8BQL7	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	Uncharacterized protein.	0.413
AMS2	B8BRT9_THAPS	B8BY56	B8BRT9	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.627
AMS2	B8BVS6_THAPS	B8BY56	B8BVS6	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	Methylenetetrahydrofolate reductase.	0.627
AMS2	B8C2Y3_THAPS	B8BY56	B8C2Y3	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	Uncharacterized protein.	0.627