(11 nodes) Thiolase-like network (Thalassiosira pseudonana)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HMCS1	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (449 aa)
	THAPSDRAFT_961	Ketoacyl_synth_N domain-containing protein. (565 aa)
	B8CGL7_THAPS	PKS_KS domain-containing protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (419 aa)
	KAS3	3-oxoacyl-synthase. (380 aa)
	AAT1_1	Acetyl-coa acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (408 aa)
	KAS2	Probable beta-ketoacyl-acyl carrier protein synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (470 aa)
	KCT1	3-ketoacyl-coa thiolase, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
	B8C1R1_THAPS	3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (465 aa)
	KCS1	3-ketoacyl-CoA synthase. (551 aa)
	B8BYB3_THAPS	Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (472 aa)
	KCT2	3-ketoacyl-coa thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (409 aa)

Your Current Organism:

Thalassiosira pseudonana

NCBI taxonomy Id: 35128
Other names: T. pseudonana

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AAT1_1	B8BYB3_THAPS	B8C5Z6	B8BYB3	Acetyl-coa acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.928
AAT1_1	HMCS1	B8C5Z6	B8BSY2	Acetyl-coa acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.994
AAT1_1	KCS1	B8C5Z6	B8BZW4	Acetyl-coa acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	3-ketoacyl-CoA synthase.	0.623
AAT1_1	KCT1	B8C5Z6	B8C459	Acetyl-coa acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	3-ketoacyl-coa thiolase, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family.	0.925
AAT1_1	KCT2	B8C5Z6	B8LC01	Acetyl-coa acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	3-ketoacyl-coa thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.933
B8BYB3_THAPS	AAT1_1	B8BYB3	B8C5Z6	Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-coa acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.928
B8BYB3_THAPS	HMCS1	B8BYB3	B8BSY2	Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.992
B8BYB3_THAPS	KCS1	B8BYB3	B8BZW4	Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	3-ketoacyl-CoA synthase.	0.655
B8BYB3_THAPS	KCT1	B8BYB3	B8C459	Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	3-ketoacyl-coa thiolase, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family.	0.960
B8BYB3_THAPS	KCT2	B8BYB3	B8LC01	Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	3-ketoacyl-coa thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.919
B8C1R1_THAPS	HMCS1	B8C1R1	B8BSY2	3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.455
B8C1R1_THAPS	KAS2	B8C1R1	B8C5X7	3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	Probable beta-ketoacyl-acyl carrier protein synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.911
B8C1R1_THAPS	KAS3	B8C1R1	B8CGL6	3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	3-oxoacyl-synthase.	0.990
B8C1R1_THAPS	THAPSDRAFT_961	B8C1R1	B8BSY1	3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	Ketoacyl_synth_N domain-containing protein.	0.906
B8CGL7_THAPS	HMCS1	B8CGL7	B8BSY2	PKS_KS domain-containing protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.455
B8CGL7_THAPS	KAS3	B8CGL7	B8CGL6	PKS_KS domain-containing protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	3-oxoacyl-synthase.	0.825
HMCS1	AAT1_1	B8BSY2	B8C5Z6	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Acetyl-coa acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.994
HMCS1	B8BYB3_THAPS	B8BSY2	B8BYB3	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.992
HMCS1	B8C1R1_THAPS	B8BSY2	B8C1R1	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.455
HMCS1	B8CGL7_THAPS	B8BSY2	B8CGL7	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	PKS_KS domain-containing protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.455