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| | purD | KEGG: vpa:VP2898 phosphoribosylamine-glycine ligase; TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; protein of unknown function DUF201; Belongs to the GARS family. (428 aa) |
| | Maqu_3484 | KEGG: abo:ABO_0289 hypothetical protein. (622 aa) |
| | Maqu_3501 | PFAM: inositol monophosphatase; KEGG: hch:HCH_06096 archaeal fructose-1,6-bisphosphatase and related enzyme of inositol monophosphatase family. (274 aa) |
| | thiG | Thiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (269 aa) |
| | Maqu_3504 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: pfl:PFL_5851 thiamine biosynthesis protein ThiS. (66 aa) |
| | pdxA | 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (336 aa) |
| | Maqu_3515 | PFAM: ribulose-phosphate 3-epimerase; KEGG: hch:HCH_06112 ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (228 aa) |
| | dut | Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (153 aa) |
| | Maqu_3563 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (404 aa) |
| | coaD | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (160 aa) |
| | Maqu_3590 | Palmitoyl-CoA hydrolase; PFAM: acyl-CoA thioesterase; KEGG: hch:HCH_00781 acyl-CoA thioesterase II. (286 aa) |
| | Maqu_3593 | PFAM: phosphoribosyltransferase; KEGG: gsu:GSU1017 hypoxanthine phosphoribosyltransferase, putative. (185 aa) |
| | Maqu_3630 | PFAM: thioesterase superfamily protein; KEGG: hch:HCH_00745 acyl-CoA hydrolase. (134 aa) |
| | thiI | [ThiS-adenylate] sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (484 aa) |
| | Maqu_3682 | KEGG: pfo:Pfl_1743 1-acyl-sn-glycerol-3-phosphate acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (239 aa) |
| | Maqu_3760 | TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase; KEGG: pfl:PFL_5834 dihydroorotase, multifunctional complex type. (437 aa) |
| | pyrB | KEGG: hch:HCH_00553 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (336 aa) |
| | Maqu_3764 | PFAM: protein of unknown function DUF179; KEGG: hch:HCH_00550 putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family. (188 aa) |
| | folE | PFAM: GTP cyclohydrolase I; KEGG: csa:Csal_2294 GTP cyclohydrolase I. (189 aa) |
| | Maqu_3856 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (352 aa) |
| | glmU | UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the t [...] (454 aa) |
| | atpC | ATP synthase F1 subcomplex epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (140 aa) |
| | atpD | ATP synthase F1 subcomplex beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (464 aa) |
| | atpG | ATP synthase F1 subcomplex gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (287 aa) |
| | Maqu_0089 | TIGRFAM: acetoacetyl-CoA synthase; PFAM: AMP-dependent synthetase and ligase; KEGG: aeh:Mlg_2108 acetoacetyl-CoA synthase. (662 aa) |
| | Maqu_0142 | PFAM: metallophosphoesterase; KEGG: hch:HCH_02241 hypothetical protein. (283 aa) |
| | pdxH | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (211 aa) |
| | Maqu_0157 | PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: mca:MCA0827 HD domain protein. (201 aa) |
| | Maqu_0217 | KEGG: tbd:Tbd_2296 putative phosphonate metabolism protein PhnG; K06166 PhnG protein. (163 aa) |
| | Maqu_0218 | PFAM: phosphonate metabolism; KEGG: tbd:Tbd_2295 putative PhnH protein, phosphonate metabolism, function unknown. (192 aa) |
| | Maqu_0219 | PFAM: phosphonate metabolism; KEGG: tbd:Tbd_2294 phosphonate metabolism protein. (379 aa) |
| | Maqu_0220 | Phosphonate metabolism PhnJ; Catalyzes the breakage of the C-P bond in alpha-D-ribose 1- methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose. Belongs to the PhnJ family. (299 aa) |
| | Maqu_0222 | KEGG: tcx:Tcr_2087 ABC transporter related; TIGRFAM: phosphonate C-P lyase system protein PhnL; PFAM: ABC transporter related; SMART: AAA ATPase. (253 aa) |
| | Maqu_0223 | PFAM: amidohydrolase; Amidohydrolase 3; KEGG: tbd:Tbd_2290 amidohydrolase-like protein. (382 aa) |
| | phnN | Phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN; Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP). (189 aa) |
| | Maqu_0225 | PFAM: beta-lactamase domain protein; KEGG: tbd:Tbd_2288 phosphonate metabolism protein, PhnP. (261 aa) |
| | Maqu_0269 | PFAM: Phosphoglycerate mutase; KEGG: abo:ABO_2379 alpha-ribazole-5'-phosphate phosphatase, putative. (207 aa) |
| | Maqu_0282 | PFAM: glycosyl transferase, family 39; KEGG: she:Shewmr4_3882 glycosyl transferase, family 39. (582 aa) |
| | Maqu_0284 | PFAM: glycosyl transferase, family 2; KEGG: shm:Shewmr7_3977 glycosyl transferase, family 2. (255 aa) |
| | Maqu_0287 | PFAM: glycosyl transferase, family 39; KEGG: pau:PA14_63700 hypothetical protein. (515 aa) |
| | Maqu_0288 | PFAM: glycosyl transferase, family 2; KEGG: net:Neut_0041 glycosyl transferase, family 2. (335 aa) |
| | Maqu_0357 | NAD pyrophosphatase/5'-nucleotidase NadN; KEGG: hch:HCH_00409 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; TIGRFAM: NAD pyrophosphatase/5'-nucleotidase NadN; PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; Belongs to the 5'-nucleotidase family. (607 aa) |
| | Maqu_0474 | PFAM: Ppx/GppA phosphatase; KEGG: hch:HCH_00283 exopolyphosphatase; Belongs to the GppA/Ppx family. (508 aa) |
| | mobA | Molybdenum cofactor guanylyltransferase; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (196 aa) |
| | Maqu_0477 | PFAM: molybdopterin biosynthesis MoaE; KEGG: hch:HCH_05229 molybdopterin converting factor, large subunit. (148 aa) |
| | Maqu_0478 | TIGRFAM: molybdopterin converting factor, subunit 1; PFAM: thiamineS protein; KEGG: mfa:Mfla_1262 molybdopterin converting factor, subunit 1. (86 aa) |
| | Maqu_0479 | Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (404 aa) |
| | Maqu_0480 | Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family. (190 aa) |
| | Maqu_0492 | PFAM: adenylate cyclase, class-I; KEGG: hch:HCH_00295 adenylate cyclase. (949 aa) |
| | Maqu_0505 | PFAM: phospholipase D/Transphosphatidylase; KEGG: bxe:Bxe_A1666 putative cardiolipin synthetase; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. (478 aa) |
| | Maqu_0529 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (199 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (212 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (210 aa) |
| | Maqu_0636 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (714 aa) |
| | plsY | Acyl-phosphate glycerol-3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (197 aa) |
| | pgi | PFAM: phosphoglucose isomerase (PGI); KEGG: hch:HCH_06266 glucose-6-phosphate isomerase; Belongs to the GPI family. (553 aa) |
| | thiE | Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (222 aa) |
| | Maqu_0688 | PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: mca:MCA0629 phosphomethylpyrimidine kinase, putative. (253 aa) |
| | coaX | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. (242 aa) |
| | Maqu_0793 | PFAM: lipid A biosynthesis acyltransferase; KEGG: hch:HCH_00023 lauroyl/myristoyl acyltransferase. (302 aa) |
| | lpxL | Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A). (318 aa) |
| | thiC | Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (654 aa) |
| | Maqu_0813 | TIGRFAM: HAD-superfamily hydrolase, subfamily IB (PSPase-like); HAD-superfamily subfamily IB hydrolase, TIGR01490; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: abo:ABO_2350 hypothetical protein. (228 aa) |
| | thiL | Thiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (315 aa) |
| | Maqu_0848 | Phosphatidylglycerophosphatase; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). (174 aa) |
| | Maqu_0861 | FMN adenylyltransferase / riboflavin kinase; KEGG: csa:Csal_0480 riboflavin biosynthesis protein RibF; TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase / FAD synthetase; Belongs to the ribF family. (322 aa) |
| | ispH | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (316 aa) |
| | nadE | DNA-directed RNA polymerase, subunit H; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (554 aa) |
| | Maqu_0885 | KEGG: hch:HCH_05913 CDP-diacylglycerol--serine O-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (271 aa) |
| | accA | acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (317 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (542 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (431 aa) |
| | ispD | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (233 aa) |
| | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (159 aa) |
| | surE | 3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (256 aa) |
| | Maqu_0928 | PFAM: protein of unknown function DUF368; KEGG: vch:VCA0040 hypothetical protein. (329 aa) |
| | dcd | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. (188 aa) |
| | purN | Formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (220 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: hch:HCH_01906 phosphoribosylaminoimidazole (AIR) synthetase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein. (354 aa) |
| | Maqu_0948 | PFAM: CDP-alcohol phosphatidyltransferase; KEGG: hch:HCH_01908 phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (186 aa) |
| | Maqu_0952 | KEGG: pfl:PFL_0851 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. (279 aa) |
| | Maqu_0991 | PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: ilo:IL2074 glyoxalase/dioxygenase superfamily protein. (133 aa) |
| | purU | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (284 aa) |
| | cmk | KEGG: hch:HCH_04979 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region. (226 aa) |
| | pyrF | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (236 aa) |
| | pyrD | Dihydroorotate oxidase A; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (340 aa) |
| | Maqu_1058 | PFAM: fructose-bisphosphate aldolase, class-I; KEGG: net:Neut_1996 fructose-bisphosphate aldolase. (339 aa) |
| | Maqu_1100 | Putative adenylate/guanylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; MASE2 domain protein; KEGG: hch:HCH_04487 adenylate cyclase, family 3. (479 aa) |
| | Maqu_1118 | PFAM: inositol monophosphatase; KEGG: hch:HCH_04465 archaeal fructose-1,6-bisphosphatase and related enzyme of inositol monophosphatase family. (270 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (142 aa) |
| | ispG | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (372 aa) |
| | Maqu_1132 | Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (717 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (401 aa) |
| | Maqu_1155 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (407 aa) |
| | Maqu_1193 | KEGG: hch:HCH_04043 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (184 aa) |
| | Maqu_1231 | KEGG: ssn:SSO_2538 EutII; TIGRFAM: phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase. (327 aa) |
| | Maqu_1245 | Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (95 aa) |
| | Maqu_1262 | PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: xac:XAC3952 hypothetical protein. (769 aa) |
| | Maqu_1263 | SMART: TIR protein; KEGG: rha:RHA1_ro09117 hypothetical protein. (255 aa) |
| | Maqu_1307 | PFAM: 5-nucleotidase; KEGG: ppu:PP_2531 5-nucleotidase, putative. (308 aa) |
| | Maqu_1345 | PFAM: FAD dependent oxidoreductase; KEGG: hch:HCH_04624 glycerol-3-phosphate dehydrogenase. (532 aa) |
| | Maqu_1380 | PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: hch:HCH_03685 2-oxoglutarate dehydrogenase E2. (528 aa) |
| | gpsA | PFAM: NADP oxidoreductase, coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Ketopantoate reductase ApbA/PanE, N-terminal domain protein; KEGG: hch:HCH_02763 glycerol-3-phosphate dehydrogenase. (353 aa) |
| | Maqu_1480 | SMART: metal-dependent phosphohydrolase, HD region; KEGG: hch:HCH_02760 HD superfamily phosphohydrolase. (494 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (507 aa) |
| | accD | acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (309 aa) |
| | Maqu_1616 | PFAM: phospholipid/glycerol acyltransferase; KEGG: hch:HCH_02752 1-acyl-sn-glycerol-3-phosphate acyltransferase. (271 aa) |
| | Maqu_1679 | PFAM: CDP-alcohol phosphatidyltransferase; KEGG: csa:Csal_1179 CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (251 aa) |
| | purC | KEGG: csa:Csal_2813 phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. (237 aa) |
| | nadA | Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily. (353 aa) |
| | guaA | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (525 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (494 aa) |
| | Maqu_1730 | PFAM: AMP-dependent synthetase and ligase; KEGG: aeh:Mlg_1396 AMP-dependent synthetase and ligase. (624 aa) |
| | lpxK | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (353 aa) |
| | Maqu_1764 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase C-terminal domain protein; KEGG: csa:Csal_2446 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (455 aa) |
| | Maqu_1827 | PFAM: FAD dependent oxidoreductase; KEGG: pha:PSHAa0189 sn-glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (513 aa) |
| | glk | Glucokinase; KEGG: hch:HCH_00434 glucokinase; TIGRFAM: glucokinase; PFAM: Glucokinase; Belongs to the bacterial glucokinase family. (321 aa) |
| | Maqu_1831 | PFAM: pyruvate kinase; KEGG: hch:HCH_00431 pyruvate kinase; Belongs to the pyruvate kinase family. (482 aa) |
| | pgl | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (237 aa) |
| | zwf | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (491 aa) |
| | folD | Methenyltetrahydrofolate cyclohydrolase / 5,10-methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (304 aa) |
| | lpxH | UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (244 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (214 aa) |
| | plsX | Phosphate:acyl-[acyl carrier protein] acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (340 aa) |
| | Maqu_1872 | Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids; Belongs to the Maf family. YceF subfamily. (197 aa) |
| | rne | RNAse E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. (1056 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (321 aa) |
| | upp | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (212 aa) |
| | Maqu_1994 | Flagellar protein export ATPase FliI; KEGG: hch:HCH_05190 flagellum-specific ATP synthase; TIGRFAM: ATPase, FliI/YscN family; flagellar protein export ATPase FliI; PFAM: H+-transporting two-sector ATPase, alpha/beta subunit, central region; H+-transporting two-sector ATPase, alpha/beta subunit domain protein; SMART: AAA ATPase. (463 aa) |
| | purE | 5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (163 aa) |
| | purK | 5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (372 aa) |
| | nadK | NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (294 aa) |
| | Maqu_2083 | PFAM: CinA domain protein; KEGG: yps:YPTB0822 putative competence-damaged protein; Belongs to the CinA family. (166 aa) |
| | Maqu_2100 | PFAM: phospholipase D/Transphosphatidylase; KEGG: ppr:PBPRB1025 hypothetical protein. (506 aa) |
| | Maqu_2125 | 3-methylcrotonoyl-CoA carboxylase, alpha subunit; PFAM: biotin/lipoyl attachment domain-containing protein; phosphoribosylglycinamide synthetase; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: ilo:IL0877 3-methylcrotonyl-CoA carboxylase alpha chain. (662 aa) |
| | Maqu_2178 | PFAM: diacylglycerol kinase, catalytic region; KEGG: gbe:GbCGDNIH1_0844 diacylglycerol kinase family protein. (297 aa) |
| | acsA | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (649 aa) |
| | Maqu_2227 | PFAM: NUDIX hydrolase; KEGG: pau:PA14_40950 putative NADH pyrophosphatase; Belongs to the Nudix hydrolase family. (294 aa) |
| | plsB | PFAM: phospholipid/glycerol acyltransferase; KEGG: hch:HCH_05086 glycerol-3-phosphate O-acyltransferase; Belongs to the GPAT/DAPAT family. (823 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (217 aa) |
| | Maqu_2237 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: hch:HCH_01808 predicted pyrophosphatase. (279 aa) |
| | Maqu_2238 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (745 aa) |
| | Maqu_2264 | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (542 aa) |
| | Maqu_2288 | PFAM: amidohydrolase; Amidohydrolase 3; KEGG: ana:all2221 phosphonate metabolism protein. (410 aa) |
| | Maqu_2289 | KEGG: tbd:Tbd_2296 putative phosphonate metabolism protein PhnG; K06166 PhnG protein. (164 aa) |
| | Maqu_2290 | PFAM: phosphonate metabolism; KEGG: tbd:Tbd_2295 putative PhnH protein, phosphonate metabolism, function unknown. (197 aa) |
| | Maqu_2291 | PFAM: phosphonate metabolism; KEGG: tbd:Tbd_2294 phosphonate metabolism protein. (374 aa) |
| | Maqu_2292 | Phosphonate metabolism PhnJ; Catalyzes the breakage of the C-P bond in alpha-D-ribose 1- methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose. Belongs to the PhnJ family. (302 aa) |
| | Maqu_2294 | Phosphonate C-P lyase system protein PhnL; KEGG: tbd:Tbd_2291 ABC phosphonate transport system ATPase; TIGRFAM: phosphonate C-P lyase system protein PhnL; PFAM: ABC transporter related; SMART: AAA ATPase. (236 aa) |
| | phnN-2 | Phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN; Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP). (189 aa) |
| | Maqu_2297 | PFAM: beta-lactamase domain protein; KEGG: tbd:Tbd_2288 phosphonate metabolism protein, PhnP. (251 aa) |
| | glpK | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (493 aa) |
| | Maqu_2323 | PFAM: phospholipid/glycerol acyltransferase; KEGG: hch:HCH_01754 1-acyl-sn-glycerol-3-phosphate acyltransferase. (272 aa) |
| | Maqu_2358 | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: pfo:Pfl_4746 UBA/ThiF-type NAD/FAD binding fold. (248 aa) |
| | ispE | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (287 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (316 aa) |
| | pfp | Pyrophosphate-dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (420 aa) |
| | nadD | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (216 aa) |
| | Maqu_2429 | KEGG: pfo:Pfl_4024 acyl-CoA thioesterase II, putative. (284 aa) |
| | thyA | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (279 aa) |
| | dxs | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (643 aa) |
| | moaC | GTP cyclohydrolase subunit MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (160 aa) |
| | lpxC | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (304 aa) |
| | Maqu_2465 | KEGG: pfo:Pfl_4686 phosphoheptose isomerase. (196 aa) |
| | purT | Formate-dependent phosphoribosylglycinamide formyltransferase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (400 aa) |
| | Maqu_2481 | PFAM: NUDIX hydrolase; KEGG: pfl:PFL_1085 hydrolase, NUDIX family. (195 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1301 aa) |
| | pyrC | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (343 aa) |
| | lpxB | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (392 aa) |
| | lpxA | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (263 aa) |
| | fabZ | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (145 aa) |
| | lpxD | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (341 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (394 aa) |
| | Maqu_2543 | PFAM: phosphatidate cytidylyltransferase; KEGG: pfo:Pfl_1106 phosphatidate cytidylyltransferase; Belongs to the CDS family. (281 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (242 aa) |
| | Maqu_2595 | KEGG: bth:BT3374 putative carbamoyl-phosphate-synthetase. (398 aa) |
| | cysQ | 3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (255 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (205 aa) |
| | Maqu_2725 | Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (200 aa) |
| | Maqu_2741 | Transporter-associated region; PFAM: CBS domain containing protein; transporter-associated region; KEGG: hch:HCH_05351 putative Mg2+ and Co2+ transporter CorC. (281 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (431 aa) |
| | nnrE | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] (520 aa) |
| | psd | Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (286 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (180 aa) |
| | Maqu_2910 | PFAM: thioesterase superfamily protein; KEGG: cbu:CBU_1269 long chain acyl-CoA thioester hydrolase family protein. (165 aa) |
| | Maqu_2970 | PFAM: nucleoside 2-deoxyribosyltransferase; KEGG: atc:AGR_L_1489 hypothetical protein. (204 aa) |
| | Maqu_3037 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa) |
| | pgk | PFAM: phosphoglycerate kinase; KEGG: hch:HCH_01537 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (386 aa) |
| | Maqu_3039 | Erythrose 4-phosphate dehydrogenase; PFAM: glyceraldehyde 3-phosphate dehydrogenase; KEGG: hch:HCH_01536 D-erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (342 aa) |
| | Maqu_3040 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (666 aa) |
| | moaA | GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (330 aa) |
| | gpmI | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (519 aa) |
| | Maqu_3185 | PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: sde:Sde_0208 hypothetical protein. (725 aa) |
| | Maqu_3252 | PFAM: pyruvate kinase; KEGG: mmc:Mmcs_0383 pyruvate kinase. (626 aa) |
| | Maqu_3283 | PFAM: phospholipase D/Transphosphatidylase; KEGG: bpe:BP3092 putative phospholipase D protein. (505 aa) |
| | Maqu_3327 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (552 aa) |
| | Maqu_3328 | 2-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (887 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (252 aa) |
| | carB | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain, oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: psp:PSPPH_4202 carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. (1072 aa) |
| | carA | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase, small chain; KEGG: pae:PA4758 carbamoyl-phosphate synthase small chain; Belongs to the CarA family. (381 aa) |
| | Maqu_3392 | Cardiolipin synthetase 2; PFAM: phospholipase D/Transphosphatidylase; KEGG: mfa:Mfla_1169 phospholipase D/transphosphatidylase. (476 aa) |
| | Maqu_3400 | PFAM: phospholipid/glycerol acyltransferase; KEGG: lpn:lpg0551 1-acyl-sn-glycerol-3-phosphate acetyltransferase. (254 aa) |
| | Maqu_3403 | PFAM: metallophosphoesterase; KEGG: hch:HCH_04892 predicted phosphohydrolase. (323 aa) |
| | Maqu_3404 | PFAM: protein of unknown function DUF46; KEGG: hch:HCH_02040 CDP-diglyceride synthetase. (160 aa) |
| | rpiA | Ribose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (225 aa) |
| | Maqu_3445 | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (448 aa) |
| | purH | IMP cyclohydrolase; KEGG: hch:HCH_06011 bifunctional purine biosynthesis protein PurH; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme, formylation region. (526 aa) |
| | atpA | ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (514 aa) |
| | atpH | ATP synthase F1 subcomplex delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (178 aa) |
| | atpF | ATP synthase F0 subcomplex B subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (156 aa) |
| | atpE | ATP synthase F0 subcomplex C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (73 aa) |
| | atpB | ATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (284 aa) |
