STRINGSTRING
argG argG ttcA ttcA tyrS tyrS Gura_1211 Gura_1211 Gura_1212 Gura_1212 Gura_1224 Gura_1224 Gura_1346 Gura_1346 Gura_1351 Gura_1351 mnmA mnmA Gura_1601 Gura_1601 Gura_1602 Gura_1602 Gura_1603 Gura_1603 Gura_1690 Gura_1690 valS valS panC panC gluQ gluQ Gura_2250 Gura_2250 gltX gltX argS argS Gura_2415 Gura_2415 Gura_2416 Gura_2416 Gura_2474 Gura_2474 coaD coaD Gura_2597 Gura_2597 Gura_2686 Gura_2686 tilS tilS Gura_2933 Gura_2933 Gura_3037 Gura_3037 Gura_3038 Gura_3038 guaA guaA leuS leuS metG metG Gura_3157 Gura_3157 hldE hldE Gura_3554 Gura_3554 Gura_3557 Gura_3557 Gura_3645 Gura_3645 nadE nadE Gura_3830 Gura_3830 Gura_3906 Gura_3906 cysD cysD Gura_3935 Gura_3935 queC queC nadD nadD glnS glnS cysS cysS Gura_4272 Gura_4272 ileS ileS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
argGPFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (406 aa)
ttcAPP-loop domain protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. (252 aa)
tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (403 aa)
Gura_1211PFAM: electron transfer flavoprotein beta-subunit. (270 aa)
Gura_1212PFAM: electron transfer flavoprotein beta-subunit; electron transfer flavoprotein, alpha subunit; 4Fe-4S ferredoxin, iron-sulfur binding domain protein. (441 aa)
Gura_1224PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; Osmosensitive K+ channel His kinase sensor; UspA domain protein. (889 aa)
Gura_1346PFAM: asparagine synthase. (639 aa)
Gura_1351PFAM: asparagine synthase. (640 aa)
mnmAtRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (375 aa)
Gura_1601PFAM: electron transfer flavoprotein beta-subunit. (258 aa)
Gura_1602PFAM: electron transfer flavoprotein beta-subunit; electron transfer flavoprotein, alpha subunit. (304 aa)
Gura_1603PFAM: electron transfer flavoprotein beta-subunit; protein of unknown function DUF224, cysteine-rich region domain protein. (335 aa)
Gura_1690Hypothetical protein. (380 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (886 aa)
panCPantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (282 aa)
gluQglutamyl-tRNA synthetase, class Ic; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (311 aa)
Gura_2250TIGRFAM: tryptophanyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase, class Ib. (327 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (467 aa)
argSTIGRFAM: arginyl-tRNA synthetase. (561 aa)
Gura_2415PFAM: electron transfer flavoprotein beta-subunit; electron transfer flavoprotein, alpha subunit; 4Fe-4S ferredoxin, iron-sulfur binding domain protein. (441 aa)
Gura_2416PFAM: electron transfer flavoprotein beta-subunit. (270 aa)
Gura_24743'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase-like protein. (551 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (162 aa)
Gura_2597Hypothetical protein. (207 aa)
Gura_2686Riboflavin kinase / FMN adenylyltransferase; TIGRFAM: riboflavin biosynthesis protein RibF; cytidyltransferase-related domain; PFAM: Riboflavin kinase / FAD synthetase; cytidylyltransferase; Belongs to the ribF family. (320 aa)
tilStRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (459 aa)
Gura_2933PFAM: UspA domain protein. (147 aa)
Gura_3037PFAM: electron transfer flavoprotein beta-subunit; electron transfer flavoprotein, alpha subunit. (305 aa)
Gura_3038PFAM: electron transfer flavoprotein beta-subunit. (286 aa)
guaAGMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (516 aa)
leuSTIGRFAM: leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (824 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (509 aa)
Gura_3157PFAM: protein of unknown function DUF218. (199 aa)
hldED-alpha,beta-D-heptose 7-phosphate 1-kinase / D-beta-D-heptose 1-phosphate adenylyltransferase; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the C-terminal section; belongs to the cytidylyltransferase family. (490 aa)
Gura_3554PFAM: electron transfer flavoprotein beta-subunit. (296 aa)
Gura_3557PFAM: electron transfer flavoprotein, alpha subunit. (334 aa)
Gura_3645PFAM: UspA domain protein. (151 aa)
nadENH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (273 aa)
Gura_3830Sulfate adenylyltransferase subunit 2; PFAM: phosphoadenosine phosphosulfate reductase. (265 aa)
Gura_3906PFAM: PP-loop domain protein. (296 aa)
cysDTIGRFAM: sulfate adenylyltransferase, small subunit; PFAM: phosphoadenosine phosphosulfate reductase. (312 aa)
Gura_3935Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. (231 aa)
queCpreQ(0) biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (228 aa)
nadDNicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (216 aa)
glnSTIGRFAM: glutaminyl-tRNA synthetase; PFAM: glutamyl-tRNA synthetase, class Ic. (568 aa)
cysSTIGRFAM: cysteinyl-tRNA synthetase; PFAM: cysteinyl-tRNA synthetase, class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family. (494 aa)
Gura_4272PFAM: thiamine biosynthesis protein. (334 aa)
ileSIsoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (924 aa)
Your Current Organism:
Geobacter uraniireducens
NCBI taxonomy Id: 351605
Other names: G. uraniireducens Rf4, Geobacter uraniireducens Rf4, Geobacter uraniireducens str. Rf4, Geobacter uraniireducens strain Rf4, Geobacter uraniumreducens JCM 13001
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.