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Acel_0031 Acel_0031 Acel_0032 Acel_0032 Acel_0033 Acel_0033 gpmA gpmA Acel_0115 Acel_0115 Acel_0283 Acel_0283 Acel_0284 Acel_0284 sucC sucC sucD sucD Acel_0387 Acel_0387 Acel_0388 Acel_0388 Acel_0394 Acel_0394 ppc ppc Acel_0520 Acel_0520 Acel_0521 Acel_0521 ackA ackA Acel_0548 Acel_0548 Acel_0549 Acel_0549 Acel_0573 Acel_0573 Acel_0586 Acel_0586 Acel_0588 Acel_0588 Acel_0589 Acel_0589 pdhA pdhA Acel_0690 Acel_0690 Acel_0700 Acel_0700 Acel_0701 Acel_0701 Acel_0702 Acel_0702 Acel_0721 Acel_0721 Acel_0801 Acel_0801 Acel_0874 Acel_0874 Acel_0935 Acel_0935 Acel_0936 Acel_0936 Acel_0979 Acel_0979 pfp pfp Acel_1046 Acel_1046 Acel_1047 Acel_1047 Acel_1048 Acel_1048 Acel_1068 Acel_1068 Acel_1080 Acel_1080 Acel_1093 Acel_1093 Acel_1114 Acel_1114 pgk pgk pgl pgl Acel_1123 Acel_1123 zwf zwf Acel_1125 Acel_1125 tal tal Acel_1127 Acel_1127 Acel_1213 Acel_1213 Acel_1214 Acel_1214 Acel_1377 Acel_1377 Acel_1394 Acel_1394 Acel_1611 Acel_1611 Acel_1647 Acel_1647 Acel_1656 Acel_1656 Acel_1657 Acel_1657 Acel_1658 Acel_1658 Acel_1674 Acel_1674 Acel_1680 Acel_1680 Acel_1681 Acel_1681 Acel_1799 Acel_1799 Acel_1864 Acel_1864 Acel_1865 Acel_1865 Acel_1877 Acel_1877 fumC fumC eno eno prs prs Acel_1956 Acel_1956 acsA acsA Acel_2125 Acel_2125
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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Acel_0031PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: sco:SCO3815 putative dihydrolipoamide acyltransferase component. (546 aa)
Acel_0032PFAM: Transketolase, central region; Transketolase domain protein; KEGG: sco:SCO3816 putative branched-chain alpha keto acid dehydrogenase E1 beta subunit. (327 aa)
Acel_0033PFAM: dehydrogenase, E1 component; KEGG: tfu:Tfu_0180 pyruvate dehydrogenase (lipoamide). (372 aa)
gpmAPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (252 aa)
Acel_0115PFAM: Citrate synthase; KEGG: sco:SCO4388 citrate synthase; Belongs to the citrate synthase family. (368 aa)
Acel_0283PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: sma:SAV4876 2-oxoglutarate ferredoxin oxidoreductase, beta subunit. (361 aa)
Acel_0284PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: tfu:Tfu_2674 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit. (623 aa)
sucCsuccinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (392 aa)
sucDsuccinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (295 aa)
Acel_0387Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. (330 aa)
Acel_0388KEGG: tfu:Tfu_2568 isocitrate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (407 aa)
Acel_0394Pyridine nucleotide-disulfide oxidoreductase dimerization region; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; KEGG: tfu:Tfu_2559 dihydrolipoamide dehydrogenase. (463 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (915 aa)
Acel_0520CoA-binding domain protein; PFAM: GCN5-related N-acetyltransferase; CoA-binding domain protein; KEGG: tfu:Tfu_1311 hypothetical protein. (911 aa)
Acel_0521PFAM: D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; KEGG: fra:Francci3_3546 fructose-6-phosphate phosphoketolase. (797 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (344 aa)
Acel_0548PFAM: phosphoribosylglycinamide synthetase; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: gka:GK1599 acetyl-CoA carboxylase. (454 aa)
Acel_0549PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: fra:Francci3_3765 biotin/lipoyl attachment. (71 aa)
Acel_0573Glucokinase; PFAM: ROK family protein; KEGG: mta:Moth_0832 glucokinase ROK. (341 aa)
Acel_0586TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase, E1 component; catalytic domain of components of various dehydrogenase complexes; Transketolase, central region; KEGG: tfu:Tfu_0566 2-oxoglutarate dehydrogenase, E1 component. (1233 aa)
Acel_0588Catalytic domain of components of various dehydrogenase complexes; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (449 aa)
Acel_0589Transketolase, central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (331 aa)
pdhAPyruvate dehydrogenase (acetyl-transferring); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (375 aa)
Acel_0690TIGRFAM: mercuric reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: cjk:jk1442 putative mercuric reductase. (481 aa)
Acel_0700TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: rfr:Rfer_2187 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate. (194 aa)
Acel_0701Pyruvate ferredoxin oxidoreductase, alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rfr:Rfer_2186 pyruvate flavodoxin/ferredoxin oxidoreductase-like. (396 aa)
Acel_0702Pyruvate ferredoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: rfr:Rfer_2185 thiamine pyrophosphate enzyme-like TPP-binding. (327 aa)
Acel_0721PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: sto:ST2350 hypothetical protein. (283 aa)
Acel_0801KEGG: sma:SAV5654 putative pyruvate phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilizing enzyme; pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile region; Belongs to the PEP-utilizing enzyme family. (896 aa)
Acel_0874Propionyl-CoA carboxylase; PFAM: carboxyl transferase; KEGG: fra:Francci3_3485 propionyl-CoA carboxylase. (474 aa)
Acel_09352-oxoglutarate dehydrogenase E2 component; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: fra:Francci3_3135 dehydrogenase subunit. (476 aa)
Acel_0936TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD dependent oxidoreductase; KEGG: sma:SAV6024 putative dihydrolipoamide dehydrogenase. (459 aa)
Acel_0979Glucokinase; TIGRFAM: putative glucokinase, ROK family; PFAM: ROK family protein; KEGG: fra:Francci3_3092 glucokinase ROK. (314 aa)
pfpPyrophosphate-dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (341 aa)
Acel_1046Pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase, E1 component; KEGG: bha:BH0776 acetoin dehydrogenase (TPP-dependent) alpha chain. (342 aa)
Acel_1047PFAM: Transketolase, central region; Transketolase domain protein; KEGG: sso:SSO1526 pyruvate dehydrogenase E1 component, beta subunit. (327 aa)
Acel_1048PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: pac:PPA0693 dihydrolipoamide acyltransferase. (76 aa)
Acel_1068PFAM: AMP-dependent synthetase and ligase; KEGG: sru:SRU_1684 acetyl-CoA synthase. (713 aa)
Acel_1080PFAM: pyruvate kinase; KEGG: sma:SAV6217 putative pyruvate kinase; Belongs to the pyruvate kinase family. (481 aa)
Acel_1093TIGRFAM: 4-aminobutyrate aminotransferase; PFAM: aminotransferase class-III; KEGG: fra:Francci3_3824 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (441 aa)
Acel_1114KEGG: tfu:Tfu_2017 glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa)
pgkPhosphoglycerate kinase / triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (687 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (254 aa)
Acel_1123KEGG: sma:SAV6312 oxppcycle protein. (314 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (508 aa)
Acel_1125PFAM: phosphoglucose isomerase (PGI); KEGG: tfu:Tfu_2004 glucose-6-phosphate isomerase; Belongs to the GPI family. (542 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (372 aa)
Acel_1127Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (692 aa)
Acel_1213TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; KEGG: sco:SCO3495 putative 2-dehydro-3-deoxyphosphogluconate aldolase / 4-hydroxy-2-oxoglutarate aldolase. (214 aa)
Acel_1214PFAM: PfkB domain protein; KEGG: sco:SCO3494 putative 2-dehydro-3-deoxygluconokinase; Belongs to the carbohydrate kinase PfkB family. (329 aa)
Acel_1377PFAM: ROK family protein; KEGG: spr:spr0584 glucose kinase. (346 aa)
Acel_1394Aconitase; TIGRFAM: aconitate hydratase 1; PFAM: aconitate hydratase domain protein; KEGG: fra:Francci3_1312 aconitate hydratase 1. (926 aa)
Acel_1611Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (438 aa)
Acel_1647Malate dehydrogenase (oxaloacetate-decarboxylating); PFAM: malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: rba:RB307 NAD-dependent malic enzyme. (504 aa)
Acel_16562-methylcitrate dehydratase; PFAM: MmgE/PrpD family protein; KEGG: rpc:RPC_3512 2-methylcitrate dehydratase. (499 aa)
Acel_16572,3-dimethylmalate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. (306 aa)
Acel_1658KEGG: mbo:Mb1162 citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase; Belongs to the citrate synthase family. (373 aa)
Acel_1674PFAM: Aldose 1-epimerase; KEGG: blo:BL1360 hypothetical protein in aldose epimerase family. (325 aa)
Acel_1680Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter; Belongs to the GroES chaperonin family. (108 aa)
Acel_1681PFAM: Alcohol dehydrogenase GroES domain protein; KEGG: nfa:nfa35140 putative dehydrogenase. (350 aa)
Acel_1799TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: tfu:Tfu_0687 methylmalonate-semialdehyde dehydrogenase. (496 aa)
Acel_1864TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: ferredoxin; KEGG: nfa:nfa56030 putative succinate dehydrogenase iron-sulfur subunit. (260 aa)
Acel_1865PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; KEGG: sco:SCO5107 putative succinate dehydrogenase flavoprotein subunit. (598 aa)
Acel_1877TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX family protein; KEGG: sma:SAV3215 putative glycerol-inducible protein. (349 aa)
fumCFumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (472 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (429 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (325 aa)
Acel_1956PFAM: aldehyde dehydrogenase; KEGG: sma:SAV7134 putative aldehyde dehydrogenase. (457 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (657 aa)
Acel_2125Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (342 aa)
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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