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Acel_0145 Acel_0145 Acel_0167 Acel_0167 moaC moaC Acel_0169 Acel_0169 Acel_0472 Acel_0472 Acel_0498 Acel_0498 Acel_0499 Acel_0499 Acel_0500 Acel_0500 Acel_0501 Acel_0501 Acel_0502 Acel_0502 Acel_0503 Acel_0503 Acel_0504 Acel_0504 Acel_0505 Acel_0505 Acel_0506 Acel_0506 Acel_0507 Acel_0507 Acel_0508 Acel_0508 Acel_0509 Acel_0509 Acel_0510 Acel_0510 Acel_0511 Acel_0511 Acel_0512 Acel_0512 Acel_0513 Acel_0513 Acel_0610 Acel_0610 Acel_0665 Acel_0665 Acel_0666 Acel_0666 fdhD fdhD Acel_0803 Acel_0803 Acel_1615 Acel_1615 Acel_1616 Acel_1616 Acel_1617 Acel_1617 cysD cysD cysC cysC moaA moaA Acel_1743 Acel_1743 Acel_1744 Acel_1744 Acel_1745 Acel_1745 Acel_1746 Acel_1746 Acel_1747 Acel_1747 Acel_2024 Acel_2024 Acel_2036 Acel_2036 Acel_2037 Acel_2037 Acel_2038 Acel_2038 Acel_2039 Acel_2039 Acel_2040 Acel_2040 Acel_2041 Acel_2041 Acel_2042 Acel_2042 Acel_2043 Acel_2043 cysH cysH Acel_2055 Acel_2055
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Acel_0145PFAM: Rieske [2Fe-2S] domain protein; TQO small subunit DoxD; DoxX family protein; KEGG: sma:SAV3474 hypothetical protein. (381 aa)
Acel_0167Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (414 aa)
moaCGTP cyclohydrolase subunit MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (158 aa)
Acel_0169TIGRFAM: molybdenum cofactor synthesis domain; PFAM: molybdopterin binding domain; KEGG: tfu:Tfu_0376 molybdopterin binding domain. (170 aa)
Acel_0472PFAM: molybdopterin biosynthesis MoaE; KEGG: fra:Francci3_3785 molybdopterin biosynthesis MoaE. (157 aa)
Acel_0498PFAM: protein of unknown function DUF59; KEGG: pho:PH0311 hypothetical protein. (111 aa)
Acel_04994Fe-4S ferredoxin, iron-sulfur binding domain protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. (117 aa)
Acel_0500KEGG: dar:Daro_3949 hypothetical protein. (385 aa)
Acel_0501PFAM: regulatory protein, ArsR; KEGG: mpa:MAP2725c hypothetical protein. (255 aa)
Acel_0502KEGG: tfu:Tfu_2795 hypothetical protein. (145 aa)
Acel_0503PFAM: multicopper oxidase, type 2; multicopper oxidase, type 3; KEGG: tfu:Tfu_2794 hypothetical protein. (479 aa)
Acel_0504Hypothetical protein. (125 aa)
Acel_0505PFAM: major facilitator superfamily MFS_1; KEGG: cpe:CPE2274 probable nitrate extrusion protein. (437 aa)
Acel_0506TIGRFAM: respiratory nitrate reductase, gamma subunit; PFAM: Nitrate reductase, gamma subunit; KEGG: sco:SCO0219 putative nitrate reductase delta chain NarI2. (250 aa)
Acel_0507TIGRFAM: nitrate reductase molybdenum cofactor assembly chaperone; PFAM: Nitrate reductase, delta subunit; KEGG: sco:SCO0218 putative nitrate reductase delta chain NarJ2. (226 aa)
Acel_0508TIGRFAM: nitrate reductase, beta subunit; KEGG: sco:SCO0217 nitrate reductase beta chain NarH2. (549 aa)
Acel_0509PFAM: molydopterin dinucleotide-binding region; KEGG: sco:SCO0216 nitrate reductase alpha chain NarG2; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (628 aa)
Acel_0510PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; KEGG: nfa:nfa45490 putative nitrate reductase alpha subunit. (596 aa)
Acel_0511KEGG: mag:amb3531 hypothetical protein. (79 aa)
Acel_0512Hypothetical protein. (118 aa)
Acel_0513KEGG: pac:PPA0092 hypothetical protein. (438 aa)
Acel_0610KEGG: tfu:Tfu_1737 oxidoreductase alpha (molybdopterin) subunit; TIGRFAM: oxidoreductase alpha (molybdopterin) subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (768 aa)
Acel_0665KEGG: fra:Francci3_3490 molybdopterin-guanine dinucleotide biosynthesis protein A-like. (242 aa)
Acel_0666Hypothetical protein; KEGG: sco:SCO3828 molybdopterin-guanine dinucleotide biosynthesis protein. (94 aa)
fdhDFormate dehydrogenase, subunit FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. (320 aa)
Acel_0803PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sco:SCO7117 ferredoxin reductase. (409 aa)
Acel_1615PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: tfu:Tfu_1890 putative secreted protein. (248 aa)
Acel_1616TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: tfu:Tfu_2221 uroporphyrin-III C-methyltransferase, C-terminal:siroheme synthase, N-terminal. (475 aa)
Acel_1617Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (431 aa)
cysDTIGRFAM: sulfate adenylyltransferase, small subunit; PFAM: phosphoadenosine phosphosulfate reductase; KEGG: sma:SAV2313 putative sulfate adenylyltransferase subunit 2. (328 aa)
cysCAdenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. (229 aa)
moaAGTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (362 aa)
Acel_1743TIGRFAM: nitrite reductase [NAD(P)H], small subunit; PFAM: Rieske [2Fe-2S] domain protein; KEGG: dge:Dgeo_2392 nitrite reductase (NAD(P)H) large subunit, NirD. (148 aa)
Acel_1744TIGRFAM: nitrite reductase [NAD(P)H], large subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: fra:Francci3_0794 nitrite reductase (NAD(P)H) large subunit, NirB. (853 aa)
Acel_1745PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: nar:Saro_2968 nitrite reductase (NAD(P)H) large subunit, NirB. (474 aa)
Acel_1746Assimilatory nitrate reductase (NADH) alpha subunit apoprotein; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: fra:Francci3_0863 molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (704 aa)
Acel_1747PFAM: major facilitator superfamily MFS_1; KEGG: cpe:CPE2274 probable nitrate extrusion protein. (449 aa)
Acel_2024PFAM: thiamineS protein; KEGG: fra:Francci3_0445 thiamine S. (92 aa)
Acel_2036Hypothetical protein. (159 aa)
Acel_2037Putative anti-sigma regulatory factor, serine/threonine protein kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; KEGG: sco:SCO0542 hypothetical regulatory protein. (182 aa)
Acel_2038PFAM: ABC transporter related; TOBE domain protein; SMART: AAA ATPase; KEGG: sma:SAV1721 putative ABC transporter ATP-binding protein. (384 aa)
Acel_2039NifC-like ABC-type porter; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (267 aa)
Acel_2040TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; PFAM: extracellular solute-binding protein, family 1; KEGG: nfa:nfa43280 putative transporter. (283 aa)
Acel_2041TIGRFAM: DNA binding domain, excisionase family; PFAM: regulatory protein, MerR; TOBE domain protein; KEGG: nfa:nfa43270 putative transporter. (132 aa)
Acel_2042KEGG: sco:SCO1113 hypothetical protein. (373 aa)
Acel_2043Hypothetical protein. (108 aa)
cysHPhosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (256 aa)
Acel_2055PFAM: thiamineS protein; nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region; KEGG: pai:PAE2577 ferredoxin-nitrite reductase. (639 aa)
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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