STRINGSTRING
Acel_0039 Acel_0039 Acel_0040 Acel_0040 Acel_0158 Acel_0158 Acel_0455 Acel_0455 Acel_0496 Acel_0496 Acel_0497 Acel_0497 Acel_0551 Acel_0551 Acel_0662 Acel_0662 Acel_0663 Acel_0663 Acel_0687 Acel_0687 Acel_0691 Acel_0691 Acel_0692 Acel_0692 Acel_0769 Acel_0769 Acel_0884 Acel_0884 Acel_0885 Acel_0885 Acel_0886 Acel_0886 Acel_0887 Acel_0887 Acel_0888 Acel_0888 Acel_0889 Acel_0889 Acel_0890 Acel_0890 Acel_0891 Acel_0891 Acel_0892 Acel_0892 Acel_0893 Acel_0893 Acel_0894 Acel_0894 Acel_0895 Acel_0895 Acel_0896 Acel_0896 Acel_0897 Acel_0897 Acel_0898 Acel_0898 Acel_0899 Acel_0899 Acel_0900 Acel_0900 Acel_0901 Acel_0901 Acel_0902 Acel_0902 Acel_0921 Acel_0921 Acel_1039 Acel_1039 Acel_1040 Acel_1040 Acel_1041 Acel_1041 Acel_1042 Acel_1042 Acel_1043 Acel_1043 Acel_1044 Acel_1044 Acel_1045 Acel_1045 Acel_1094 Acel_1094 Acel_1095 Acel_1095 Acel_1097 Acel_1097 Acel_1098 Acel_1098 Acel_1099 Acel_1099 Acel_1100 Acel_1100 Acel_1101 Acel_1101 Acel_1102 Acel_1102 Acel_1103 Acel_1103 Acel_1104 Acel_1104 Acel_1105 Acel_1105 Acel_1463 Acel_1463 Acel_1464 Acel_1464 Acel_1465 Acel_1465 Acel_1466 Acel_1466 Acel_1467 Acel_1467 Acel_1468 Acel_1468 Acel_1470 Acel_1470 Acel_1471 Acel_1471 Acel_1472 Acel_1472 Acel_1630 Acel_1630 Acel_1631 Acel_1631 Acel_1632 Acel_1632 Acel_1633 Acel_1633 Acel_1634 Acel_1634 Acel_1635 Acel_1635 Acel_1636 Acel_1636 Acel_1637 Acel_1637 Acel_1638 Acel_1638 Acel_1639 Acel_1639 Acel_1640 Acel_1640 Acel_1641 Acel_1641 Acel_1642 Acel_1642 Acel_1643 Acel_1643 Acel_1644 Acel_1644 Acel_1645 Acel_1645 Acel_1646 Acel_1646 Acel_1664 Acel_1664 Acel_1666 Acel_1666 Acel_1667 Acel_1667 Acel_1673 Acel_1673 Acel_1692 Acel_1692 Acel_1709 Acel_1709 Acel_1710 Acel_1710 Acel_1711 Acel_1711 Acel_1717 Acel_1717 Acel_1767 Acel_1767 Acel_1848 Acel_1848 Acel_1849 Acel_1849 Acel_1850 Acel_1850 Acel_1851 Acel_1851 Acel_1852 Acel_1852 Acel_1853 Acel_1853 Acel_1854 Acel_1854 fbiD fbiD Acel_1962 Acel_1962 Acel_2056 Acel_2056 Acel_2122 Acel_2122
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Acel_0039PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; 3-demethylubiquinone-9 3-methyltransferase; KEGG: tbd:Tbd_1204 PhnB protein. (143 aa)
Acel_0040Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR; Tetracyclin repressor domain protein; KEGG: fra:Francci3_1243 transcriptional regulator, TetR family. (211 aa)
Acel_0158Methylthioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage. (273 aa)
Acel_0455LPPG:FO 2-phospho-L-lactate transferase; TIGRFAM: LPPG; PFAM: protein of unknown function UPF0052 and CofD; KEGG: tfu:Tfu_2517 LPPG:Fo 2-phospho-L-lactate transferase. (390 aa)
Acel_0496KEGG: sco:SCO4689 hypothetical protein. (111 aa)
Acel_0497Alkylhydroperoxidase like protein, AhpD family; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. (114 aa)
Acel_0551Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; UbiC transcription regulator-associated domain protein; KEGG: sma:SAV3023 putative GntR-family transcriptional regulator. (268 aa)
Acel_0662KEGG: lxx:Lxx21660 hypothetical protein. (207 aa)
Acel_0663TIGRFAM: peptidase S26B, signal peptidase; PFAM: peptidase S24, S26A and S26B; KEGG: lxx:Lxx21650 signal peptidase I. (618 aa)
Acel_0687PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sco:SCO1088 oxidoreductase. (234 aa)
Acel_0691PFAM: regulatory protein, TetR; KEGG: nfa:nfa31030 putative transcriptional regulator. (218 aa)
Acel_0692PFAM: Cupin 2, conserved barrel domain protein; KEGG: fra:Francci3_2969 cupin 2. (163 aa)
Acel_0769FO synthase subunit 1 / FO synthase subunit 2; KEGG: fra:Francci3_0745 conserved hypothetical protein; TIGRFAM: conserved hypothetical protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB. (884 aa)
Acel_0884PFAM: Cupin 2, conserved barrel domain protein. (116 aa)
Acel_0885PFAM: Endoribonuclease L-PSP; KEGG: hch:HCH_06312 putative translation initiation inhibitor, YjgF family. (155 aa)
Acel_0886PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rsp:RSP_2598 ABC transporter, inner membrane subunit. (255 aa)
Acel_0887PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rsp:RSP_0644 ABC transporter, inner membrane subunit. (276 aa)
Acel_0888PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mba:Mbar_A1030 ABC transporter, ATP-binding protein. (284 aa)
Acel_0889ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components-like protein; KEGG: reu:Reut_A2720 extracellular solute-binding protein, family 3. (390 aa)
Acel_0890PFAM: protein of unknown function DUF1100, hydrolase family protein; KEGG: cvi:CV0865 probable dipeptidyl aminopeptidase; Belongs to the UPF0255 family. (357 aa)
Acel_0891PFAM: Carboxymuconolactone decarboxylase; KEGG: bte:BTH_I0996 carboxymuconolactone decarboxylase family protein. (218 aa)
Acel_0892Transcriptional regulator, LacI family; PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: reu:Reut_B5848 periplasmic binding protein/LacI transcriptional regulator. (391 aa)
Acel_0893ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components-like protein; KEGG: ypm:pMT054 putative periplasmic protein. (305 aa)
Acel_0894KEGG: dsy:DSY0977 hypothetical protein. (405 aa)
Acel_0895PFAM: Carboxymuconolactone decarboxylase; KEGG: rba:RB4395 probable macrophage infectivity potentiator protein Mip. (205 aa)
Acel_0896PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: pae:PA1602 probable oxidoreductase. (168 aa)
Acel_0897PFAM: aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding; KEGG: bja:blr6047 putative oxidoreductase protein. (713 aa)
Acel_0898PFAM: NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding; KEGG: pae:PA2199 probable dehydrogenase. (314 aa)
Acel_0899Hypothetical protein. (156 aa)
Acel_0900PFAM: protein of unknown function DUF34; KEGG: mpa:MAP1982c hypothetical protein; Belongs to the GTP cyclohydrolase I type 2/NIF3 family. (393 aa)
Acel_0901PFAM: protein of unknown function DUF164; KEGG: fra:Francci3_1437 protein of unknown function DUF164. (237 aa)
Acel_0902PFAM: ribonuclease H; Phosphoglycerate mutase; KEGG: tfu:Tfu_1953 hypothetical protein. (411 aa)
Acel_0921PFAM: major facilitator superfamily MFS_1; KEGG: tfu:Tfu_2854 hypothetical protein. (442 aa)
Acel_1039PFAM: oxidoreductase domain protein. (376 aa)
Acel_1040PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mlo:mlr2047 short chain dehydrogenase. (231 aa)
Acel_1041PFAM: Cupin 2, conserved barrel domain protein. (311 aa)
Acel_1042PFAM: amidohydrolase; Amidohydrolase 3; KEGG: reu:Reut_C6231 hypothetical protein. (451 aa)
Acel_1043PFAM: peptidase M24; KEGG: hma:rrnB0212 aminopeptidase. (449 aa)
Acel_1044Transcriptional regulator, XRE family with cupin sensor; PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein; KEGG: sil:SPO0423 DNA-binding protein, putative. (212 aa)
Acel_1045PFAM: 6-phosphogluconate dehydrogenase, NAD-binding; KEGG: gme:Gmet_3011 6-phosphogluconate dehydrogenase, NAD-binding. (305 aa)
Acel_1094PFAM: glutamine amidotransferase class-I; KEGG: tel:tll1969 probable amino transferase. (238 aa)
Acel_1095PFAM: cytochrome P450; KEGG: nar:Saro_2608 cytochrome P450 family protein. (414 aa)
Acel_1097PFAM: Acetoacetate decarboxylase; KEGG: nar:Saro_2597 acetoacetate decarboxylase. (275 aa)
Acel_1098Transcriptional regulator, MarR family; PFAM: regulatory protein, MarR; KEGG: bld:BLi00667 YwaE. (171 aa)
Acel_1099PFAM: peptidase C26; KEGG: mta:Moth_2164 peptidase C26. (243 aa)
Acel_1100PFAM: aldehyde dehydrogenase; KEGG: nar:Saro_2610 betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (493 aa)
Acel_1101PFAM: Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B; KEGG: bte:BTH_II0234 class III extradiol-type catecholic dioxygenase, putative. (303 aa)
Acel_1102PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: nar:Saro_2598 5-carboxymethyl-2-hydroxymuconate delta-isomerase. (290 aa)
Acel_1103KEGG: mba:Mbar_A1947 hypothetical protein. (73 aa)
Acel_1104PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sma:SAV1609 ferredoxin reductase. (414 aa)
Acel_1105Amino acid/polyamine/organocation transporter, APC superfamily; PFAM: amino acid permease-associated region; KEGG: nfa:nfa27870 putative permease; TC 2.A.3. (516 aa)
Acel_1463KEGG: fra:Francci3_4387 putative integral membrane protein. (552 aa)
Acel_1464PFAM: pyridoxamine 5'-phosphate oxidase-related, FMN-binding; KEGG: sma:SAV7483 hypothetical protein. (200 aa)
Acel_1465PFAM: luciferase family protein; KEGG: sma:SAV7484 N5,N10-methylenetetrahydromethanopterin reductase-related protein. (275 aa)
Acel_1466KEGG: cgl:NCgl1234 hypothetical protein. (548 aa)
Acel_1467PFAM: protein of unknown function DUF1707; KEGG: cjk:jk1672 hypothetical protein. (144 aa)
Acel_1468PFAM: GCN5-related N-acetyltransferase; KEGG: sco:SCO1091 acetyltransferase. (202 aa)
Acel_1470FAD linked oxidase domain protein; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; protein of unknown function DUF224, cysteine-rich region domain protein; FAD linked oxidase domain protein; KEGG: fra:Francci3_0962 D-lactate dehydrogenase (cytochrome). (997 aa)
Acel_1471PFAM: protein of unknown function DUF894, DitE; major facilitator superfamily MFS_1; KEGG: sma:SAV3157 export protein. (420 aa)
Acel_1472PFAM: major facilitator superfamily MFS_1; KEGG: hma:rrnAC2836 sugar and other transporter. (458 aa)
Acel_1630KEGG: sco:SCO6244 hypothetical protein. (212 aa)
Acel_1631PFAM: protein of unknown function DUF182; KEGG: sma:SAV1536 xanthine dehydrogenase accessory factor. (357 aa)
Acel_1632KEGG: gvi:gll0959 hypothetical protein. (207 aa)
Acel_1633PFAM: purine catabolism PurC domain protein; KEGG: mta:Moth_2125 transcriptional regulator, CdaR. (601 aa)
Acel_1634KEGG: mth:MTH1911 hypothetical protein. (326 aa)
Acel_1635PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: mlo:mlr7936 diaminopropionate ammonia-lyase. (402 aa)
Acel_1636PFAM: carbon monoxide dehydrogenase subunit G; KEGG: bpa:BPP0391 hypothetical protein. (237 aa)
Acel_1637Purine hydroxylase delta subunit apoprotein; PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: reu:Reut_A3075 ferredoxin:(2Fe-2S)-binding. (161 aa)
Acel_1638Carbon-monoxide dehydrogenase (acceptor); PFAM: molybdopterin dehydrogenase, FAD-binding; CO dehydrogenase flavoprotein domain protein; KEGG: ape:APE2219 292aa long hypothetical nicotine dehydrogenase chain A. (295 aa)
Acel_1639PFAM: Asp/Glu racemase; KEGG: pab:PAB2420 arylmalonate decarboxylase. (230 aa)
Acel_1640KEGG: bja:blr4464 probable ABC transporter ATP-binding/permease protein; TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; SMC domain protein; ABC transporter related; SMART: AAA ATPase; TC 3.A.1.3.-; 3.A.1.3.-. (559 aa)
Acel_1641Amino acid ABC transporter substrate-binding protein, PAAT family; PFAM: extracellular solute-binding protein, family 3; SMART: ionotropic glutamate receptor; KEGG: atc:AGR_pAT_714 putative periplasmic binding transport protein; TC 3.A.1.3.-. (302 aa)
Acel_1642Xanthine dehydrogenase, molybdenum binding subunit apoprotein; PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding; KEGG: sme:SMb20132 probable aldehyde oxidase and xanthine dehydrogenase family protein transmembrane. (782 aa)
Acel_1643PFAM: coenzyme A transferase; KEGG: plu:plu0144 unnamed protein product; similar to glutaconate CoA-transferase chain B. (261 aa)
Acel_1644Glutaconate CoA-transferase; PFAM: coenzyme A transferase; KEGG: afu:AF1199 glutaconate CoA-transferase, subunit A. (317 aa)
Acel_1645PFAM: luciferase family protein; KEGG: nfa:nfa26770 hypothetical protein. (315 aa)
Acel_1646TIGRFAM: NADPH-dependent F420 reductase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: tfu:Tfu_0970 NADPH-dependent F420 reductase. (229 aa)
Acel_1664Putative transcriptional regulator; KEGG: mbo:Mb2651 hypothetical protein. (209 aa)
Acel_1666KEGG: fra:Francci3_4216 transposase IS116/IS110/IS902. (100 aa)
Acel_1667PFAM: transposase, IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: fra:Francci3_4216 transposase IS116/IS110/IS902. (312 aa)
Acel_1673TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: sma:SAV5648 efflux membrane protein. (530 aa)
Acel_1692Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (443 aa)
Acel_1709PFAM: regulatory protein, TetR; KEGG: dvu:DVU2819 transcriptional regulator, TetR family. (224 aa)
Acel_1710PFAM: protein of unknown function DUF1486; KEGG: pfo:Pfl_4651 hypothetical protein. (142 aa)
Acel_1711PFAM: short-chain dehydrogenase/reductase SDR; KEGG: eba:c1A58 (S)-1-Phenylethanol dehydrogenase. (252 aa)
Acel_1717PFAM: isochorismatase hydrolase; KEGG: pac:PPA0993 pyrazinamidase/nicotinamidase. (207 aa)
Acel_1767KEGG: fra:Francci3_1839 hypothetical protein. (59 aa)
Acel_1848Peptidase C26; PFAM: glutamine amidotransferase class-I; peptidase C26; KEGG: mbo:Mb2884c possible amidotransferase. (251 aa)
Acel_1849PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sma:SAV6727 short chain dehydrogenase. (255 aa)
Acel_1850PFAM: aldehyde dehydrogenase; KEGG: mtc:MT2926 aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. (453 aa)
Acel_1851PFAM: glutamine synthetase, catalytic region; KEGG: sma:SAV6725 putative glutamine synthetase. (446 aa)
Acel_1852Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; GntR domain protein; Helix-turn-helix, type 11 domain protein; KEGG: sma:SAV6724 GntR-family transcriptional regulator. (252 aa)
Acel_1853Amino acid/polyamine/organocation transporter, APC superfamily; PFAM: amino acid permease-associated region; KEGG: sma:SAV4122 amino acid permease; TC 2.A.3. (528 aa)
Acel_1854PFAM: ATPase, BadF/BadG/BcrA/BcrD type; KEGG: sth:STH292 hypothetical protein. (289 aa)
fbiDConserved hypothetical protein; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor. (260 aa)
Acel_1962Coenzyme F420-0 gamma-glutamyl ligase; TIGRFAM: F420-dependent oxidoreductase, putative; PFAM: nitroreductase; protein of unknown function DUF129; KEGG: sco:SCO3037 putative oxidoreductase. (430 aa)
Acel_2056PFAM: Na+/solute symporter; KEGG: sco:SCO5229 putative permease; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (527 aa)
Acel_2122PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mpa:MAP3856 hypothetical protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (249 aa)
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.