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Acel_0713 Acel_0713 Acel_0898 Acel_0898 Acel_1784 Acel_1784 Acel_1813 Acel_1813 Acel_1820 Acel_1820 gcvT gcvT Acel_0048 Acel_0048 dtd dtd Acel_0672 Acel_0672 Acel_0248 Acel_0248 Acel_1045 Acel_1045 Acel_1102 Acel_1102 gcvP gcvP gcvH gcvH Acel_1288 Acel_1288 Acel_1291 Acel_1291 Acel_0626 Acel_0626 pdxT pdxT Acel_1441 Acel_1441 Acel_1442 Acel_1442 Acel_1443 Acel_1443 Acel_1562 Acel_1562 Acel_1657 Acel_1657 Acel_1749 Acel_1749
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
Acel_07135-carboxymethyl-2-hydroxymuconate delta-isomerase; PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: fra:Francci3_3626 5-carboxymethyl-2-hydroxymuconate delta-isomerase. (267 aa)
Acel_0898PFAM: NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding; KEGG: pae:PA2199 probable dehydrogenase. (314 aa)
Acel_1784KEGG: sma:SAV3097 hypothetical protein. (224 aa)
Acel_1813PFAM: Phytanoyl-CoA dioxygenase; KEGG: sma:SAV7190 hypothetical protein. (393 aa)
Acel_1820TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: 6-phosphogluconate dehydrogenase domain protein; 6-phosphogluconate dehydrogenase, NAD-binding; KEGG: mpa:MAP2670c 6-phosphogluconate dehydrogenase. (344 aa)
gcvTAminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. (386 aa)
Acel_0048D-mannonate dehydratase; PFAM: Mandelate racemase/muconate lactonizing enzyme, N-terminal domain protein; Mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein; KEGG: ccr:CC2812 mandelate racemase / muconate lactonizing enzyme family. (405 aa)
dtdD-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (142 aa)
Acel_0672KEGG: tfu:Tfu_2394 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
Acel_0248PFAM: Proline dehydrogenase; KEGG: tfu:Tfu_0434 proline dehydrogenase. (317 aa)
Acel_1045PFAM: 6-phosphogluconate dehydrogenase, NAD-binding; KEGG: gme:Gmet_3011 6-phosphogluconate dehydrogenase, NAD-binding. (305 aa)
Acel_1102PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: nar:Saro_2598 5-carboxymethyl-2-hydroxymuconate delta-isomerase. (290 aa)
gcvPGlycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (964 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (130 aa)
Acel_1288TIGRFAM: alanine dehydrogenase; PFAM: alanine dehydrogenase/PNT domain protein; KEGG: nfa:nfa16250 putative L-alanine dehydrogenase; Belongs to the AlaDH/PNT family. (372 aa)
Acel_1291Phosphopantothenate-cysteine ligase / Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (415 aa)
Acel_0626KEGG: tfu:Tfu_0875 thiolase; TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
pdxTPyridoxal phosphate synthase yaaE subunit; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (207 aa)
Acel_1441TIGRFAM: phenylacetate-CoA oxygenase, PaaI subunit; PFAM: phenylacetic acid catabolic family protein; KEGG: rpb:RPB_3639 phenylacetate-CoA oxygenase, PaaI subunit. (252 aa)
Acel_1442TIGRFAM: phenylacetate-CoA oxygenase, PaaH subunit; PFAM: phenylacetic acid degradation B; KEGG: sma:SAV4353 putative phenylacetic acid degradation protein. (97 aa)
Acel_1443TIGRFAM: phenylacetate-CoA oxygenase, PaaG subunit; PFAM: phenylacetic acid catabolic family protein; KEGG: sma:SAV4354 putative phenylacetic acid degradation protein. (320 aa)
Acel_1562PFAM: amidohydrolase; Amidohydrolase 3; KEGG: fra:Francci3_3462 amidohydrolase 3. (362 aa)
Acel_16572,3-dimethylmalate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. (306 aa)
Acel_1749PFAM: NAD-glutamate dehydrogenase; KEGG: sma:SAV5075 NAD-glutamate dehydrogenase. (1584 aa)
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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