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KLU14459.1 KLU14459.1 KLU13951.1 KLU13951.1 KLU17240.1 KLU17240.1 KLU17241.1 KLU17241.1 KLU17252.1 KLU17252.1 KLU17253.1 KLU17253.1 KLU17254.1 KLU17254.1 KLU17255.1 KLU17255.1 KLU17256.1 KLU17256.1 KLU17257.1 KLU17257.1 KLU17259.1 KLU17259.1 KLU17260.1 KLU17260.1 KLU17261.1 KLU17261.1 paaB paaB paaA paaA KLU17321.1 KLU17321.1 KLU17306.1 KLU17306.1 gcvT gcvT KLU16435.1 KLU16435.1 KLU16436.1 KLU16436.1 KLU16221.1 KLU16221.1 KLU16223.1 KLU16223.1 KLU16195.1 KLU16195.1 KLU16196.1 KLU16196.1 KLU16197.1 KLU16197.1 gabD gabD KLU16202.1 KLU16202.1 KLU16205.1 KLU16205.1 KLU16169.1 KLU16169.1 KLU15755.1 KLU15755.1 KLU15597.1 KLU15597.1 KLU15666.1 KLU15666.1 KLU15656.1 KLU15656.1 astD astD KLU15658.1 KLU15658.1 KLU15503.1 KLU15503.1 KLU15518.1 KLU15518.1 KLU15520.1 KLU15520.1 prpB prpB KLU15467.1 KLU15467.1 KLU14585.1 KLU14585.1 KLU14612.1 KLU14612.1 nagB nagB KLU14834.1 KLU14834.1 KLU14876.1 KLU14876.1 murQ murQ fadA fadA fadB fadB KLU15242.1 KLU15242.1 KLU15305.1 KLU15305.1 KLU15272.1 KLU15272.1 KLU15271.1 KLU15271.1 KLU15270.1 KLU15270.1 KLU15355.1 KLU15355.1 anmK anmK KLU15380.1 KLU15380.1 fadE fadE KLU17317.1 KLU17317.1 KLU16931.1 KLU16931.1 KLU16938.1 KLU16938.1 KLU16973.1 KLU16973.1 KLU16864.1 KLU16864.1 KLU16729.1 KLU16729.1 fadJ fadJ KLU16733.1 KLU16733.1 KLU16780.1 KLU16780.1 KLU16736.1 KLU16736.1 KLU16737.1 KLU16737.1 KLU16547.1 KLU16547.1 KLU16370.1 KLU16370.1 KLU16373.1 KLU16373.1 putA putA tdh tdh KLU14249.1 KLU14249.1 fadH fadH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KLU14459.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (512 aa)
KLU13951.1Phenylacetaldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (476 aa)
KLU17240.1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa)
KLU17241.1Long-chain-fatty-acyl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (811 aa)
KLU17252.1Phenylacetic acid degradation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)
KLU17253.1phenylacetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (439 aa)
KLU17254.1Catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa)
KLU17255.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (156 aa)
KLU17256.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (537 aa)
KLU17257.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (265 aa)
KLU17259.1Phenylacetic acid degradation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (362 aa)
KLU17260.1Phenylacetic acid degradation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (172 aa)
KLU17261.1Phenylacetic acid degradation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa)
paaBphenylacetate-CoA oxygenase; With PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; involved in phenylacetate degradation; Derived by automated computational analysis using gene prediction method: Protein Homology. (95 aa)
paaAATPase AAA; With PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
KLU17321.1enoyl-CoA hydratase; Catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (688 aa)
KLU17306.1Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; Derived by automated computational analysis using gene prediction method: Protein Homology. (145 aa)
gcvTGlycine cleavage system protein T; Catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa)
KLU16435.1Glycine cleavage system protein H; Part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; Derived by automated computational analysis using gene prediction method: Protein Homology. (130 aa)
KLU16436.1Glycine dehydrogenase; Acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; Derived by automated computational analysis using gene prediction method: Protein Homology. (958 aa)
KLU16221.1Betaine-aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (492 aa)
KLU16223.1Deoxygluconate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa)
KLU16195.12-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
KLU16196.12-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa)
KLU16197.1Betaine-aldehyde dehydrogenase; Catalyzes the formation of betaine from betaine aldehyde; Derived by automated computational analysis using gene prediction method: Protein Homology. (488 aa)
gabDSuccinate-semialdehyde dehydrogenase; Catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. (490 aa)
KLU16202.14-hydroxy-2-oxo-heptane-1,7-dioate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
KLU16205.1Pyoverdin chromophore biosynthetic protein pvcC; Derived by automated computational analysis using gene prediction method: Protein Homology. (520 aa)
KLU16169.1Autonomous glycyl radical cofactor GrcA; Stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (127 aa)
KLU15755.13-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
KLU15597.1Tryptophan transporter of high affinity; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa)
KLU15666.1Succinylglutamate desuccinylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)
KLU15656.1N-succinylarginine dihydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (447 aa)
astDA high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH; Derived by automated computational analysis using gene prediction method: Protein Homology. (506 aa)
KLU15658.1Arginine N-succinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
KLU15503.1Coenzyme F390 synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (430 aa)
KLU15518.1Mannonate dehydratase; Catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa)
KLU15520.1Glucuronate isomerase; Catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology. (477 aa)
prpB2-methylisocitrate lyase; Catalyzes the formation of pyruvate and succinate from 2-methylisocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology. (301 aa)
KLU15467.1Propionate catabolism operon regulatory protein PrpR; Sigma-54 dependent activator family protein; activates the prpBCDE operon; Derived by automated computational analysis using gene prediction method: Protein Homology. (556 aa)
KLU14585.1Zinc-binding dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (353 aa)
KLU14612.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (444 aa)
nagBGlucosamine-6-phosphate deaminase; Catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (268 aa)
KLU14834.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa)
KLU14876.1Lysis protein; Required for phi X174 lysis; Derived by automated computational analysis using gene prediction method: Protein Homology. (72 aa)
murQN-acetylmuramic acid-6-phosphate etherase; Catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
fadA3-ketoacyl-CoA thiolase; FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; Derived by automated computational analysis using gene prediction method: Protein Homology. (387 aa)
fadBMultifunctional fatty acid oxidation complex subunit alpha; Includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; Derived by automated computational analysis using gene prediction method: Protein Homology. (728 aa)
KLU15242.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1023 aa)
KLU15305.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa)
KLU15272.1Galactonate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (382 aa)
KLU15271.12-dehydro-3-deoxy-6-phosphogalactonate aldolase; Catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)
KLU15270.12-oxo-3-deoxygalactonate kinase; Catalyzes the formation of 2-dehydro-3-deoxy-D-galactonate 6-phosphate from 2-dehydro-3-deoxy-D-galactonate; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)
KLU15355.13-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)
anmKanhydro-N-acetylmuramic acid kinase; Catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; Derived by automated computational analysis using gene prediction method: Protein Homology. (369 aa)
KLU15380.1Amino acid dehydrogenase; Catalyzes the oxidative deamination of D-amino acids; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa)
fadEacyl-CoA dehydrogenase; Functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (815 aa)
KLU17317.1Biopolymer transporter Tol; Derived by automated computational analysis using gene prediction method: Protein Homology. (429 aa)
KLU16931.1Lysine 2,3-aminomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
KLU16938.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (497 aa)
KLU16973.1Flavoprotein; Derived by automated computational analysis using gene prediction method: Protein Homology. (191 aa)
KLU16864.1Thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (135 aa)
KLU16729.13-ketoacyl-CoA thiolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (436 aa)
fadJMultifunctional fatty acid oxidation complex subunit alpha; Multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate; Derived by automated computational analysis using gene prediction method: Protein Homology. (724 aa)
KLU16733.1Imidazolonepropionase; Derived by automated computational analysis using gene prediction method: Protein Homology. (422 aa)
KLU16780.1Formimidoylglutamase; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)
KLU16736.1Urocanate hydratase; Catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology. (564 aa)
KLU16737.1Catalyzes the degradation of histidine to urocanate and ammmonia; Derived by automated computational analysis using gene prediction method: Protein Homology. (510 aa)
KLU16547.1Purine nucleoside phosphoramidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (116 aa)
KLU16370.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (494 aa)
KLU16373.1Arginine decarboxylase; Catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (634 aa)
putATranscriptional regulator; Proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1326 aa)
tdhL-threonine 3-dehydrogenase; Converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)
KLU14249.1Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)
fadH2,4-dienoyl-CoA reductase; Catalyzes the formation of trans-2- enoyl-CoA from 2,4-dienoyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (673 aa)
Your Current Organism:
Xenorhabdus griffiniae
NCBI taxonomy Id: 351672
Other names: CIP 109073, DSM 17911, X. griffiniae, Xenorhabdus griffiniae Tailliez et al. 2006, Xenorhabdus sp. ID10, strain ID10
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