(27 nodes) Methane metabolism network (Xenorhabdus griffiniae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	KLU14898.1	Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (199 aa)
	KLU17354.1	Oxidizes malate to oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
	KLU17357.1	Catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
	KLU17219.1	acetyl-CoA synthetase; Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (651 aa)
	KLU16993.1	Phosphoglycerate mutase; Catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate; Derived by automated computational analysis using gene prediction method: Protein Homology. (215 aa)
	serB	Phosphoserine phosphatase; Catalyzes the formation of serine from O-phosphoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
	KLU16565.1	Fructose-bisphosphate aldolase; Catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (349 aa)
	KLU16623.1	3-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; catalyzes 4 phosphohydroxy L-threonine from 2-oxo 3 hydroxy 4- phosphobutanoate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; Derived by automated computational analysis using gene prediction method: Protein Homology. (362 aa)
	eno	Enolase; Catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa)
	KLU16427.1	D-3-phosphoglycerate dehydrogenase; Catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa)
	KLU16352.1	Aldehyde-activating protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (133 aa)
	KLU16208.1	Fructose-bisphosphate aldolase; Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (358 aa)
	KLU16052.1	Serine hydroxymethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (417 aa)
	KLU14732.1	Hypothetical protein; Contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA; Derived by automated computational analysis using gene prediction method: Protein Homology. (485 aa)
	KLU15961.1	Phosphoenolpyruvate carboxylase; Catalyzes the formation of oxaloacetate from phosphoenolpyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (878 aa)
	KLU15979.1	6-phosphofructokinase; Catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
	KLU15687.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (67 aa)
	KLU15654.1	AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; also known to act on propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
	KLU15655.1	Catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. (714 aa)
	KLU15264.1	Molecular chaperone; Derived by automated computational analysis using gene prediction method: Protein Homology. (180 aa)
	KLU15290.1	Transcriptional regulator; Represses the expression of the zwf, eda, glp and gap; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
	KLU14341.1	HI1409 family phage-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (558 aa)
	KLU15240.1	Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (792 aa)
	KLU15159.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
	gpmA	Phosphoglyceromutase; 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; Derived by automated computational analysis using gene prediction method: Protein Homology. (250 aa)
	KLU15086.1	HI1409 family phage-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (457 aa)
	KLU14941.1	Catalyzes the formation of S-formylglutathione from S-(hydroxymethyl)glutathione; also catalyzes the formation of aldehyde or ketone from alcohols; Derived by automated computational analysis using gene prediction method: Protein Homology. (369 aa)

Your Current Organism:

Xenorhabdus griffiniae

NCBI taxonomy Id: 351672
Other names: CIP 109073, DSM 17911, X. griffiniae, Xenorhabdus griffiniae Tailliez et al. 2006, Xenorhabdus sp. ID10, strain ID10

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KLU14941.1	KLU16352.1	AAY47_13670	AAY47_06025	Catalyzes the formation of S-formylglutathione from S-(hydroxymethyl)glutathione; also catalyzes the formation of aldehyde or ketone from alcohols; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aldehyde-activating protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.703
KLU14941.1	KLU17219.1	AAY47_13670	AAY47_00770	Catalyzes the formation of S-formylglutathione from S-(hydroxymethyl)glutathione; also catalyzes the formation of aldehyde or ketone from alcohols; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-CoA synthetase; Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.403
KLU15240.1	KLU15654.1	AAY47_11915	AAY47_10080	Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.	AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; also known to act on propionate; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.422
KLU15240.1	KLU15655.1	AAY47_11915	AAY47_10085	Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.	Catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.700
KLU15240.1	KLU15961.1	AAY47_11915	AAY47_07930	Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphoenolpyruvate carboxylase; Catalyzes the formation of oxaloacetate from phosphoenolpyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.732
KLU15240.1	KLU16208.1	AAY47_11915	AAY47_06850	Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.	Fructose-bisphosphate aldolase; Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.668
KLU15240.1	KLU16565.1	AAY47_11915	AAY47_04865	Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.	Fructose-bisphosphate aldolase; Catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.576
KLU15240.1	KLU16993.1	AAY47_11915	AAY47_02895	Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphoglycerate mutase; Catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.553
KLU15240.1	KLU17354.1	AAY47_11915	AAY47_00285	Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.	Oxidizes malate to oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.736
KLU15240.1	eno	AAY47_11915	AAY47_05285	Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.	Enolase; Catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.750
KLU15240.1	gpmA	AAY47_11915	AAY47_12265	Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphoglyceromutase; 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.627
KLU15290.1	KLU16208.1	AAY47_11600	AAY47_06850	Transcriptional regulator; Represses the expression of the zwf, eda, glp and gap; Derived by automated computational analysis using gene prediction method: Protein Homology.	Fructose-bisphosphate aldolase; Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.576
KLU15290.1	KLU16565.1	AAY47_11600	AAY47_04865	Transcriptional regulator; Represses the expression of the zwf, eda, glp and gap; Derived by automated computational analysis using gene prediction method: Protein Homology.	Fructose-bisphosphate aldolase; Catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.495
KLU15290.1	KLU16993.1	AAY47_11600	AAY47_02895	Transcriptional regulator; Represses the expression of the zwf, eda, glp and gap; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphoglycerate mutase; Catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.427
KLU15290.1	eno	AAY47_11600	AAY47_05285	Transcriptional regulator; Represses the expression of the zwf, eda, glp and gap; Derived by automated computational analysis using gene prediction method: Protein Homology.	Enolase; Catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.529
KLU15654.1	KLU15240.1	AAY47_10080	AAY47_11915	AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; also known to act on propionate; Derived by automated computational analysis using gene prediction method: Protein Homology.	Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.422
KLU15654.1	KLU15655.1	AAY47_10080	AAY47_10085	AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; also known to act on propionate; Derived by automated computational analysis using gene prediction method: Protein Homology.	Catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
KLU15654.1	KLU15979.1	AAY47_10080	AAY47_08035	AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; also known to act on propionate; Derived by automated computational analysis using gene prediction method: Protein Homology.	6-phosphofructokinase; Catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.421
KLU15654.1	KLU17219.1	AAY47_10080	AAY47_00770	AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; also known to act on propionate; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-CoA synthetase; Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.728
KLU15654.1	eno	AAY47_10080	AAY47_05285	AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; also known to act on propionate; Derived by automated computational analysis using gene prediction method: Protein Homology.	Enolase; Catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.458