STRINGSTRING
nadK nadK acpS acpS AOM42760.1 AOM42760.1 ndk ndk A9255_01080 A9255_01080 AOM39331.1 AOM39331.1 A9255_01255 A9255_01255 AOM39356.1 AOM39356.1 AOM39385.1 AOM39385.1 ackA ackA motB motB fliA fliA AOM39587.1 AOM39587.1 pgsA pgsA AOM39616.1 AOM39616.1 ppk ppk AOM39738.1 AOM39738.1 AOM39768.1 AOM39768.1 AOM39777.1 AOM39777.1 AOM39798.1 AOM39798.1 A9255_04025 A9255_04025 AOM39815.1 AOM39815.1 prs prs ispE ispE AOM39837.1 AOM39837.1 A9255_04235 A9255_04235 AOM39889.1 AOM39889.1 A9255_04710 A9255_04710 AOM39987.1 AOM39987.1 AOM40003.1 AOM40003.1 AOM40087.1 AOM40087.1 clsA clsA tdk tdk AOM40144.1 AOM40144.1 AOM40274.1 AOM40274.1 AOM40278.1 AOM40278.1 anmK anmK AOM40305.1 AOM40305.1 AOM40311.1 AOM40311.1 AOM40312.1 AOM40312.1 lplA lplA arnC arnC AOM40346.1 AOM40346.1 AOM40358.1 AOM40358.1 AOM40364.1 AOM40364.1 AOM40373.1 AOM40373.1 AOM42830.1 AOM42830.1 AOM42833.1 AOM42833.1 thiK thiK AOM40463.1 AOM40463.1 tmk tmk AOM40556.1 AOM40556.1 lpxT lpxT rcsC rcsC rcsD rcsD AOM40618.1 AOM40618.1 coaE_1 coaE_1 kdsB kdsB AOM40674.1 AOM40674.1 lpxK lpxK cmk cmk udk udk AOM40779.1 AOM40779.1 AOM40835.1 AOM40835.1 AOM40864.1 AOM40864.1 AOM40877.1 AOM40877.1 nadD nadD pssA pssA aroK aroK proB proB dinB dinB coaE coaE mraY mraY AOM42871.1 AOM42871.1 AOM41115.1 AOM41115.1 adk adk dnaX dnaX thiI thiI thiL thiL phoR phoR AOM41198.1 AOM41198.1 AOM41212.1 AOM41212.1 AOM41222.1 AOM41222.1 thrB thrB AOM41228.1 AOM41228.1 AOM41230.1 AOM41230.1 AOM41250.1 AOM41250.1 AOM41277.1 AOM41277.1 entE entE gntK gntK AOM41416.1 AOM41416.1 AOM41417.1 AOM41417.1 AOM41428.1 AOM41428.1 AOM41473.1 AOM41473.1 kptA kptA AOM41513.1 AOM41513.1 pnp pnp AOM41619.1 AOM41619.1 wecA wecA tsaC tsaC rpoA rpoA coaA coaA argB argB AOM41699.1 AOM41699.1 glpK glpK pfkA pfkA AOM41719.1 AOM41719.1 AOM41723.1 AOM41723.1 AOM41725.1 AOM41725.1 AOM41726.1 AOM41726.1 coaD coaD rph rph AOM41767.1 AOM41767.1 AOM41786.1 AOM41786.1 A9255_15290 A9255_15290 glmU glmU rbsK rbsK aroK-2 aroK-2 AOM41869.1 AOM41869.1 AOM41912.1 AOM41912.1 AOM41928.1 AOM41928.1 rpoZ rpoZ gmk gmk lsrK lsrK mobA mobA srkA srkA polA polA AOM42026.1 AOM42026.1 AOM42029.1 AOM42029.1 slyX slyX rpoB rpoB rpoC rpoC AOM42067.1 AOM42067.1 AOM42107.1 AOM42107.1 AOM42144.1 AOM42144.1 AOM42146.1 AOM42146.1 AOM42148.1 AOM42148.1 AOM42171.1 AOM42171.1 dnaG dnaG cca cca glnE glnE hldE hldE AOM42284.1 AOM42284.1 AOM42292.1 AOM42292.1 glnD glnD pyrH pyrH AOM42335.1 AOM42335.1 AOM42344.1 AOM42344.1 aceK aceK AOM42365.1 AOM42365.1 AOM42370.1 AOM42370.1 glk glk AOM42460.1 AOM42460.1 ubiB ubiB cysD cysD cysN cysN cysC cysC ispD ispD AOM42512.1 AOM42512.1 AOM42526.1 AOM42526.1 AOM42539.1 AOM42539.1 pcnB pcnB AOM42552.1 AOM42552.1 AOM42973.1 AOM42973.1 AOM42608.1 AOM42608.1 dnaQ dnaQ pgk pgk AOM42738.1 AOM42738.1 cobS cobS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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nadKNAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (299 aa)
acpSholo-ACP synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (126 aa)
AOM42760.1Two-component sensor histidine kinase; Part of the GlrKR two-component signal transduction system involved in the regulation of glmY; Derived by automated computational analysis using gene prediction method: Protein Homology. (479 aa)
ndkNucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (142 aa)
A9255_01080Acetyltransferase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (169 aa)
AOM39331.1Phosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (575 aa)
A9255_01255Ferredoxin; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (68 aa)
AOM39356.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (130 aa)
AOM39385.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (477 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (400 aa)
motBFlagellar motor protein MotB; With MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (717 aa)
fliARNA polymerase sigma factor FliA; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily. (240 aa)
AOM39587.1Sugar kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (531 aa)
pgsACDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (182 aa)
AOM39616.1Bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (265 aa)
ppkRNA degradosome polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (689 aa)
AOM39738.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (409 aa)
AOM39768.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (101 aa)
AOM39777.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (513 aa)
AOM39798.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (80 aa)
A9255_04025Transposase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (142 aa)
AOM39815.1Universal stress protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (145 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (336 aa)
ispE4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. IspE subfamily. (301 aa)
AOM39837.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (269 aa)
A9255_04235Hypothetical protein; Internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa)
AOM39889.1Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (480 aa)
A9255_04710Helicase; Frameshifted; incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (167 aa)
AOM39987.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (176 aa)
AOM40003.1DNA primase; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)
AOM40087.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)
clsACardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. (486 aa)
tdkThymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (198 aa)
AOM40144.1UTP--glucose-1-phosphate uridylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)
AOM40274.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (329 aa)
AOM40278.1DNA-binding transcriptional activator PspC; Derived by automated computational analysis using gene prediction method: Protein Homology. (120 aa)
anmKanhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (369 aa)
AOM40305.1Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (469 aa)
AOM40311.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (792 aa)
AOM40312.1Phosphoenolpyruvate synthase regulatory protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation. (287 aa)
lplALipoate--protein ligase; Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes. Belongs to the LplA family. (336 aa)
arnCUndecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase; Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. (325 aa)
AOM40346.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the fructosamine kinase family. (289 aa)
AOM40358.1DNA polymerase III subunit theta; Derived by automated computational analysis using gene prediction method: Protein Homology. (76 aa)
AOM40364.1PTS mannose transporter subunit IIAB; Derived by automated computational analysis using gene prediction method: Protein Homology. (321 aa)
AOM40373.1Two-component system sensor histidine kinase UhpB; Derived by automated computational analysis using gene prediction method: Protein Homology. (507 aa)
AOM42830.1DNA primase; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa)
AOM42833.1Sensor protein PhoQ; Derived by automated computational analysis using gene prediction method: Protein Homology. (507 aa)
thiKThiamine kinase; Catalyzes the phosphorylation of thiamine to thiamine phosphate. (286 aa)
AOM40463.1DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa)
tmkdTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (211 aa)
AOM40556.11-phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. (312 aa)
lpxTHypothetical protein; Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1- diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P); Belongs to the LpxT phosphotransferase family. (234 aa)
rcsCTwo-component system sensor histidine kinase/response regulator; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. (939 aa)
rcsDPhosphotransferase RcsD; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB. (907 aa)
AOM40618.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (420 aa)
coaE_1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa)
kdsB3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (249 aa)
AOM40674.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0434 family. (59 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (330 aa)
cmkCytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
udkUridine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)
AOM40779.1Hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. (302 aa)
AOM40835.1Two-component system sensor histidine kinase KdbD; Derived by automated computational analysis using gene prediction method: Protein Homology. (904 aa)
AOM40864.1PTS N-acetyl-D-glucosamine transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (504 aa)
AOM40877.1DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (358 aa)
nadDNicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (215 aa)
pssACatalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; Derived by automated computational analysis using gene prediction method: Protein Homology. (452 aa)
aroKShikimate kinase II; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (176 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (368 aa)
dinBDNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (351 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (207 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (360 aa)
AOM42871.14'-phosphopantetheinyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the P-Pant transferase superfamily. (246 aa)
AOM41115.1Kinase inhibitor; YbhB; similar to rat and human kinase inhibitory proteins; Derived by automated computational analysis using gene prediction method: Protein Homology. (161 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (215 aa)
dnaXDNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (674 aa)
thiItRNA 4-thiouridine(8) synthase ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (482 aa)
thiLThiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (348 aa)
phoRMembrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; Derived by automated computational analysis using gene prediction method: Protein Homology. (437 aa)
AOM41198.1Fructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
AOM41212.1Trifunctional adenylyltransferase/ribosylnicotinamide kinase/transcriptional regulator; Catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; catalyzes the formation of nicotinamide mononucleotide from nicotinamide riboside; also has a regulatory function; Derived by automated computational analysis using gene prediction method: Protein Homology. (408 aa)
AOM41222.1Bifunctional aspartate kinase/homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the homoserine dehydrogenase family. (819 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (316 aa)
AOM41228.1Molybdopterin adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (191 aa)
AOM41230.1PTS beta-glucoside transporter subunit IIABC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (458 aa)
AOM41250.1Riboflavin biosynthesis protein RibF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. (314 aa)
AOM41277.1DNA polymerase III subunit psi; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. (136 aa)
entEBifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; Derived by automated computational analysis using gene prediction method: Protein Homology. (542 aa)
gntKGluconate kinase; Thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)
AOM41416.1PTS cellobiose transporter subunit IIC; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. (432 aa)
AOM41417.1PTS sugar transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology. (101 aa)
AOM41428.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (266 aa)
AOM41473.1DNA polymerase III subunit chi; Binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; Derived by automated computational analysis using gene prediction method: Protein Homology. (159 aa)
kptARNA 2'-phosphotransferase; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase. (171 aa)
AOM41513.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (565 aa)
pnpPolyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (712 aa)
AOM41619.1Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (293 aa)
wecAUndecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55). (362 aa)
tsaCL-threonylcarbamoyladenylate synthase TsaC; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. (189 aa)
rpoADNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (329 aa)
coaAType I pantothenate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate. (257 aa)
AOM41699.1Bifunctional aspartate kinase/homoserine dehydrogenase II; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the homoserine dehydrogenase family. (811 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (507 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (325 aa)
AOM41719.1Phosphatidate cytidylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
AOM41723.1Two-component system sensor histidine kinase CpxA; Derived by automated computational analysis using gene prediction method: Protein Homology. (458 aa)
AOM41725.1Capsular biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (523 aa)
AOM41726.1Capsular biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (160 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (247 aa)
AOM41767.1YicC family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (287 aa)
AOM41786.1DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (366 aa)
A9255_15290Hypothetical protein; Internal stop; incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)
glmUUDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (461 aa)
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (309 aa)
aroK-2Shikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (173 aa)
AOM41869.1PTS trehalose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology. (477 aa)
AOM41912.1EnvZ; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa)
AOM41928.1Two-component system sensor histidine kinase NtrB; Derived by automated computational analysis using gene prediction method: Protein Homology. (349 aa)
rpoZDNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (91 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (207 aa)
lsrKAutoinducer-2 kinase; Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position. (530 aa)
mobAMolybdenum cofactor guanylyltransferase MobA; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (192 aa)
srkAStress response serine/threonine protein kinase YihE; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response. (328 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (941 aa)
AOM42026.1Phosphoribulokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (289 aa)
AOM42029.1PTS N-acetylmuramic acid transporter subunits IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology. (488 aa)
slyXLysis protein; Required for phi X174 lysis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SlyX family. (72 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1342 aa)
rpoCDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1408 aa)
AOM42067.1Molybdopterin-synthase adenylyltransferase MoeB; Derived by automated computational analysis using gene prediction method: Protein Homology. (274 aa)
AOM42107.1Glycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycerate kinase type-1 family. (377 aa)
AOM42144.1Phosphohistidinoprotein-hexose phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (90 aa)
AOM42146.1PTS IIA-like nitrogen-regulatory protein PtsN; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa)
AOM42148.1RNA polymerase factor sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (477 aa)
AOM42171.1Aerobic respiration two-component sensor histidine kinase ArcB; Derived by automated computational analysis using gene prediction method: Protein Homology. (765 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (582 aa)
ccaCCA-adding enzyme; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 2 subfamily. (390 aa)
glnEBifunctional glutamine synthetase adenylyltransferase/deadenyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of [...] (952 aa)
hldEBifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (474 aa)
AOM42284.1Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. (782 aa)
AOM42292.1Phosphoenolpyruvate--protein phosphotransferase PtsP; Member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family. (748 aa)
glnD[protein-PII] uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. (884 aa)
pyrHUMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (242 aa)
AOM42335.1CDP-diglyceride synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDS family. (287 aa)
AOM42344.1DNA polymerase III subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (1160 aa)
aceKBifunctional isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. (591 aa)
AOM42365.1Lysine-sensitive aspartokinase 3; Catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (457 aa)
AOM42370.1Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (123 aa)
glkGlucokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial glucokinase family. (322 aa)
AOM42460.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (427 aa)
ubiBUbiquinone biosynthesis regulatory protein kinase UbiB; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. (545 aa)
cysDSulfate adenylyltransferase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
cysNSulfate adenylyltransferase subunit CysN; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (480 aa)
cysCAdenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. (217 aa)
ispD2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. (265 aa)
AOM42512.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (522 aa)
AOM42526.1MASE1 sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (515 aa)
AOM42539.12-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (160 aa)
pcnBPolynucleotide adenylyltransferase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (516 aa)
AOM42552.1Two-component sensor histidine kinase BarA; Derived by automated computational analysis using gene prediction method: Protein Homology. (803 aa)
AOM42973.1Catalyzes the formation of inosine/guanosine monophosphate from inosine or guanosine and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. (436 aa)
AOM42608.1DNA primase; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)
dnaQDNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (249 aa)
pgkPhosphoglycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (388 aa)
AOM42738.15-dehydro-2-deoxygluconokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (638 aa)
cobSadenosylcobinamide-GDP ribazoletransferase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (254 aa)
Your Current Organism:
Xenorhabdus hominickii
NCBI taxonomy Id: 351679
Other names: CIP 109072, DSM 17903, X. hominickii, Xenorhabdus hominickii Taillez et al. 2006, Xenorhabdus sp. KE01, Xenorhabdus sp. KR01, Xenorhabdus sp. KR05, strain KE01
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