STRINGSTRING
AOM41998.1 AOM41998.1 AOM39252.1 AOM39252.1 AOM39328.1 AOM39328.1 cysA cysA nuoA nuoA nuoC nuoC AOM39439.1 AOM39439.1 AOM39440.1 AOM39440.1 AOM42767.1 AOM42767.1 AOM39443.1 AOM39443.1 AOM39445.1 AOM39445.1 AOM39446.1 AOM39446.1 AOM39562.1 AOM39562.1 AOM39622.1 AOM39622.1 AOM39885.1 AOM39885.1 znuC znuC AOM40013.1 AOM40013.1 AOM40243.1 AOM40243.1 btuD btuD btuC btuC AOM40343.1 AOM40343.1 AOM40344.1 AOM40344.1 AOM40345.1 AOM40345.1 AOM40451.1 AOM40451.1 lolD lolD AOM40453.1 AOM40453.1 AOM40457.1 AOM40457.1 AOM40551.1 AOM40551.1 AOM40647.1 AOM40647.1 AOM40661.1 AOM40661.1 AOM40697.1 AOM40697.1 AOM40698.1 AOM40698.1 macB macB AOM40705.1 AOM40705.1 AOM40800.1 AOM40800.1 sdhB sdhB sdhA sdhA AOM40825.1 AOM40825.1 kdpA kdpA kdpB kdpB kdpC kdpC AOM40855.1 AOM40855.1 AOM41131.1 AOM41131.1 AOM41156.1 AOM41156.1 AOM41157.1 AOM41157.1 AOM41197.1 AOM41197.1 AOM41200.1 AOM41200.1 AOM41203.1 AOM41203.1 AOM41324.1 AOM41324.1 AOM41459.1 AOM41459.1 potA potA AOM41470.1 AOM41470.1 AOM41471.1 AOM41471.1 btuB btuB argH argH atpC atpC atpD atpD atpG atpG atpA atpA atpH atpH atpF-2 atpF-2 atpE atpE atpB atpB AOM41813.1 AOM41813.1 AOM41846.1 AOM41846.1 AOM41969.1 AOM41969.1 AOM41987.1 AOM41987.1 kefG kefG kefB kefB lamB lamB malK malK malF malF malG malG frdD frdD frdC frdC AOM42087.1 AOM42087.1 AOM42088.1 AOM42088.1 AOM42112.1 AOM42112.1 AOM42149.1 AOM42149.1 AOM42266.1 AOM42266.1 AOM42314.1 AOM42314.1 AOM42356.1 AOM42356.1 metN metN AOM42403.1 AOM42403.1 AOM42431.1 AOM42431.1 AOM42454.1 AOM42454.1 tatA tatA tatB tatB tatC tatC fbpC fbpC AOM42539.1 AOM42539.1 AOM42581.1 AOM42581.1 AOM42619.1 AOM42619.1 AOM42664.1 AOM42664.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AOM41998.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (124 aa)
AOM39252.1Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (86 aa)
AOM39328.1Sulfate ABC transporter permease subunit CysW; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)
cysASulfate/thiosulfate transporter subunit; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. (362 aa)
nuoANADH-quinone oxidoreductase subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family. (143 aa)
nuoCNADH-quinone oxidoreductase subunit C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. (598 aa)
AOM39439.1NADH-quinone oxidoreductase subunit E; Derived by automated computational analysis using gene prediction method: Protein Homology. (181 aa)
AOM39440.1NADH-quinone oxidoreductase subunit F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (454 aa)
AOM42767.1NADH-quinone oxidoreductase subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (910 aa)
AOM39443.1NADH:ubiquinone oxidoreductase subunit J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (176 aa)
AOM39445.1NADH-quinone oxidoreductase subunit L; Derived by automated computational analysis using gene prediction method: Protein Homology. (624 aa)
AOM39446.1NADH-quinone oxidoreductase subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology. (506 aa)
AOM39562.1DNAse; Derived by automated computational analysis using gene prediction method: Protein Homology. (116 aa)
AOM39622.1Multidrug transporter subunit MdtA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (412 aa)
AOM39885.1Zinc ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (261 aa)
znuCZinc ABC transporter ATP-binding protein ZnuC; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family. (252 aa)
AOM40013.1DNAse; Derived by automated computational analysis using gene prediction method: Protein Homology. (116 aa)
AOM40243.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (407 aa)
btuDVitamin B12 ABC transporter ATP-binding protein BtuD; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. (255 aa)
btuCVitamin B12 ABC transporter permease BtuC; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane. (331 aa)
AOM40343.1Iron ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)
AOM40344.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)
AOM40345.1Iron ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (297 aa)
AOM40451.1Lipoprotein transporter subunit LolE; Derived by automated computational analysis using gene prediction method: Protein Homology. (415 aa)
lolDLipoprotein releasing system, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. (239 aa)
AOM40453.1Outer membrane-specific lipoprotein transporter subunit LolC; Part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
AOM40457.1NADH dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (434 aa)
AOM40551.1Iron ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (377 aa)
AOM40647.1Porin OmpA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the outer membrane OOP (TC 1.B.6) superfamily. (365 aa)
AOM40661.1Porin; Allows for ions and hydrophilic solutes to cross the outer membrane; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Gram-negative porin family. (366 aa)
AOM40697.1Cysteine/glutathione ABC transporter permease/ATP-binding protein CydD; In Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; Derived by automated computational analysis using gene prediction method: Protein Homology. (589 aa)
AOM40698.1In Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; Derived by automated computational analysis using gene prediction method: Protein Homology. (590 aa)
macBMacrolide ABC transporter permease/ATP-binding protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. (646 aa)
AOM40705.1Macrolide transporter subunit MacA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (370 aa)
AOM40800.1Molybdate ABC transporter ATP-binding protein ModF; Derived by automated computational analysis using gene prediction method: Protein Homology. (497 aa)
sdhBSuccinate dehydrogenase iron-sulfur subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (238 aa)
sdhASuccinate dehydrogenase flavoprotein subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (588 aa)
AOM40825.1Succinate dehydrogenase, cytochrome b556 subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (129 aa)
kdpAPotassium-transporting ATPase subunit KdpA; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. (565 aa)
kdpBK+-transporting ATPase subunit B; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. (688 aa)
kdpCK+-transporting ATPase subunit C; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex. (193 aa)
AOM40855.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (354 aa)
AOM41131.1Efflux transporter periplasmic adaptor subunit; With AcrD and TolC forms a transport system involved in resistance to a number of compounds including lipophilic antibiotics; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (399 aa)
AOM41156.1Cytochrome o ubiquinol oxidase subunit III; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)
AOM41157.1Cytochrome o ubiquinol oxidase subunit IV; Derived by automated computational analysis using gene prediction method: Protein Homology. (110 aa)
AOM41197.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)
AOM41200.1Porin; Allows for ions and hydrophilic solutes to cross the outer membrane; Derived by automated computational analysis using gene prediction method: Protein Homology. (382 aa)
AOM41203.1TonB system transport protein ExbD; Derived by automated computational analysis using gene prediction method: Protein Homology. (141 aa)
AOM41324.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (139 aa)
AOM41459.1Spermidine/putrescine ABC transporter permease PotB; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)
potAPutrescine/spermidine ABC transporter ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. (371 aa)
AOM41470.1Lipopolysaccharide ABC transporter permease LptG; With LptABCF is involved in the transport of lipopolysaccharides; Derived by automated computational analysis using gene prediction method: Protein Homology. (359 aa)
AOM41471.1Lipopolysaccharide ABC transporter permease LptF; With LptBGC is involved in lipopolysaccharide export; Derived by automated computational analysis using gene prediction method: Protein Homology. (366 aa)
btuBTonB-dependent vitamin B12 receptor; Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans- periplasmic membrane protein TonB; Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily. (604 aa)
argHArgininosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (457 aa)
atpCF0F1 ATP synthase subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane. (140 aa)
atpDF0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (460 aa)
atpGF0F1 ATP synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (287 aa)
atpAF0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (513 aa)
atpHATP synthase F1 subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (177 aa)
atpF-2F0F1 ATP synthase subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (156 aa)
atpEATP F0F1 synthase subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (81 aa)
atpBF0F1 ATP synthase subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (274 aa)
AOM41813.1F0F1 ATP synthase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology. (125 aa)
AOM41846.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (2397 aa)
AOM41969.1Hemolysin activation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (561 aa)
AOM41987.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (139 aa)
kefGGlutathione-regulated potassium-efflux system ancillary protein KefG; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB. (187 aa)
kefBGlutathione-regulated potassium-efflux system protein KefB; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. (602 aa)
lamBMaltoporin; Porin involved in the transport of maltose and maltodextrins; Derived by automated computational analysis using gene prediction method: Protein Homology. (425 aa)
malKMaltose/maltodextrin transporter ATP-binding protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Maltooligosaccharide importer (TC 3.A.1.1.1) family. (369 aa)
malFWith MalKGE is involved in maltose transport into the cell; Derived by automated computational analysis using gene prediction method: Protein Homology. (518 aa)
malGMaltose transporter permease; With MalKFE is involved in the transport of maltose into the cell; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa)
frdDFumarate reductase; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (117 aa)
frdCFumarate reductase subunit C; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (131 aa)
AOM42087.1Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)
AOM42088.1Fumarate reductase (quinol) flavoprotein subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (598 aa)
AOM42112.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (106 aa)
AOM42149.1LPS export ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (241 aa)
AOM42266.1Outer membrane channel protein TolC; Derived by automated computational analysis using gene prediction method: Protein Homology. (454 aa)
AOM42314.1Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (463 aa)
AOM42356.1DL-methionine transporter permease subunit; Part of the MetNIQ methionine uptake system; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa)
metND-methionine ABC transporter, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (343 aa)
AOM42403.1DNAse; Derived by automated computational analysis using gene prediction method: Protein Homology. (116 aa)
AOM42431.1HNH endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (134 aa)
AOM42454.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (420 aa)
tatAPreprotein translocase subunit TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (84 aa)
tatBTwin arginine-targeting protein translocase TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. (165 aa)
tatCTwin arginine-targeting protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. (262 aa)
fbpCFerric transporter ATP-binding subunit; Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system. (346 aa)
AOM42539.12-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (160 aa)
AOM42581.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (270 aa)
AOM42619.1Holin; Derived by automated computational analysis using gene prediction method: Protein Homology. (111 aa)
AOM42664.1DNAse; Derived by automated computational analysis using gene prediction method: Protein Homology. (118 aa)
Your Current Organism:
Xenorhabdus hominickii
NCBI taxonomy Id: 351679
Other names: CIP 109072, DSM 17903, X. hominickii, Xenorhabdus hominickii Taillez et al. 2006, Xenorhabdus sp. KE01, Xenorhabdus sp. KR01, Xenorhabdus sp. KR05, strain KE01
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