STRINGSTRING
wecF wecF wzxE wzxE wzzE wzzE wecA wecA emrB-2 emrB-2 secY secY ftsN ftsN menA menA AOM41723.1 AOM41723.1 AOM41751.1 AOM41751.1 yidC yidC atpC atpC atpD atpD atpG atpG atpA atpA atpH atpH atpF-2 atpF-2 atpE atpE atpB atpB rbsA rbsA rbsC rbsC AOM41827.1 AOM41827.1 rrf rrf AOM41869.1 AOM41869.1 AOM41874.1 AOM41874.1 glpG glpG AOM41912.1 AOM41912.1 AOM42923.1 AOM42923.1 AOM41914.1 AOM41914.1 pstB pstB AOM41918.1 AOM41918.1 AOM41919.1 AOM41919.1 gltS gltS AOM41957.1 AOM41957.1 AOM41958.1 AOM41958.1 AOM41967.1 AOM41967.1 AOM42006.1 AOM42006.1 AOM42007.1 AOM42007.1 A9255_16555 A9255_16555 AOM42029.1 AOM42029.1 kefG kefG kefB kefB secE secE malK malK malF malF malG malG AOM42082.1 AOM42082.1 frdD frdD frdC frdC AOM42937.1 AOM42937.1 ftsY ftsY ftsE ftsE AOM42104.1 AOM42104.1 AOM42118.1 AOM42118.1 A9255_17145 A9255_17145 lptC lptC AOM42941.1 AOM42941.1 AOM42171.1 AOM42171.1 mtgA mtgA AOM42185.1 AOM42185.1 plsY plsY parC parC djlA djlA thiQ thiQ thiP thiP lgt lgt AOM42313.1 AOM42313.1 syd syd AOM42336.1 AOM42336.1 AOM42356.1 AOM42356.1 metN metN ubiA ubiA plsB plsB AOM42370.1 AOM42370.1 AOM42441.1 AOM42441.1 A9255_18950 A9255_18950 AOM42456.1 AOM42456.1 ubiB ubiB tatA tatA tatB tatB tatC tatC ubiD ubiD AOM42478.1 AOM42478.1 ftsB ftsB fbpC fbpC AOM42523.1 AOM42523.1 AOM42535.1 AOM42535.1 lpxH lpxH tppB tppB AOM42743.1 AOM42743.1 cobS cobS nuoB nuoB nuoA nuoA AOM39430.1 AOM39430.1 dedD dedD AOM39385.1 AOM39385.1 AOM39375.1 AOM39375.1 zipA zipA cysZ cysZ cysA cysA AOM39327.1 AOM39327.1 AOM39315.1 AOM39315.1 AOM39308.1 AOM39308.1 era era lepA lepA aqpZ aqpZ dctA dctA mdtH mdtH murJ murJ znuC znuC lpxM lpxM AOM39893.1 AOM39893.1 AOM39894.1 AOM39894.1 AOM39960.1 AOM39960.1 AOM39980.1 AOM39980.1 rnfA rnfA rnfB rnfB rnfC rnfC rnfD rnfD rnfG rnfG rnfE rnfE lapB lapB lapA lapA AOM40121.1 AOM40121.1 AOM40123.1 AOM40123.1 AOM40130.1 AOM40130.1 clsA clsA AOM40134.1 AOM40134.1 oppB oppB AOM40224.1 AOM40224.1 nhaB nhaB dsbB dsbB AOM40276.1 AOM40276.1 AOM40283.1 AOM40283.1 AOM40284.1 AOM40284.1 AOM40301.1 AOM40301.1 mdtK mdtK AOM40317.1 AOM40317.1 hmuV hmuV arnF arnF arnE arnE arnT arnT arnC arnC btuD btuD btuC btuC htpX htpX AOM40367.1 AOM40367.1 mntP mntP AOM40391.1 AOM40391.1 hflD hflD AOM42833.1 AOM42833.1 AOM40451.1 AOM40451.1 lolD lolD AOM40453.1 AOM40453.1 mltG mltG rne rne dld dld AOM40550.1 AOM40550.1 AOM40554.1 AOM40554.1 AOM40558.1 AOM40558.1 lpxT lpxT AOM40565.1 AOM40565.1 rcsC rcsC rcsD rcsD AOM40605.1 AOM40605.1 pyrD pyrD msbA msbA AOM40694.1 AOM40694.1 macB macB AOM40710.1 AOM40710.1 artM artM AOM40738.1 AOM40738.1 modC modC modB modB tolR tolR tolQ tolQ AOM40815.1 AOM40815.1 sdhA sdhA sdhD sdhD kdpA kdpA kdpB kdpB kdpC kdpC AOM40847.1 AOM40847.1 AOM40864.1 AOM40864.1 lnt lnt AOM40873.1 AOM40873.1 AOM40874.1 AOM40874.1 mrdA mrdA mrdB mrdB AOM40886.1 AOM40886.1 crcB crcB emrB emrB AOM40899.1 AOM40899.1 AOM40900.1 AOM40900.1 aas aas gpt gpt AOM40940.1 AOM40940.1 AOM40948.1 AOM40948.1 nqrF nqrF nqrE nqrE nqrD nqrD nqrC nqrC nqrB nqrB AOM42865.1 AOM42865.1 argO argO secA secA ftsA ftsA ftsQ ftsQ murG murG ftsW ftsW mraY mraY ftsI ftsI ftsL ftsL AOM41132.1 AOM41132.1 AOM41154.1 AOM41154.1 cyoE cyoE A9255_11640 A9255_11640 secF secF secD secD yajC_2 yajC_2 AOM41230.1 AOM41230.1 nhaA nhaA lspA lspA AOM41286.1 AOM41286.1 AOM41294.1 AOM41294.1 dsbD dsbD AOM42883.1 AOM42883.1 AOM41408.1 AOM41408.1 AOM41416.1 AOM41416.1 AOM41458.1 AOM41458.1 AOM39741.1 AOM39741.1 AOM39734.1 AOM39734.1 A9255_03510 A9255_03510 AOM39715.1 AOM39715.1 AOM39624.1 AOM39624.1 mdtB mdtB mdtC mdtC AOM39611.1 AOM39611.1 pgsA pgsA AOM39543.1 AOM39543.1 AOM39531.1 AOM39531.1 fliJ fliJ fliL fliL AOM39525.1 AOM39525.1 AOM39524.1 AOM39524.1 AOM39523.1 AOM39523.1 fliP fliP fliQ fliQ AOM39521.1 AOM39521.1 flhA flhA flhB flhB AOM39489.1 AOM39489.1 lpxL lpxL lldD lldD AOM39449.1 AOM39449.1 nuoN nuoN nuoK nuoK AOM39443.1 AOM39443.1 nuoI nuoI nuoH nuoH nuoC nuoC AOM41459.1 AOM41459.1 potA potA AOM41480.1 AOM41480.1 AOM41492.1 AOM41492.1 AOM41517.1 AOM41517.1 AOM41525.1 AOM41525.1 hflB hflB cysQ cysQ psd psd corA corA wzyE wzyE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
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gene neighborhood
gene fusions
gene co-occurrence
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co-expression
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wecF4-alpha-L-fucosyltransferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family. (364 aa)
wzxEO-antigen translocase; Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA); Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family. (416 aa)
wzzEPolysaccharide chain length modulation protein; Modulates the polysaccharide chain length of enterobacterial common antigen (ECA); Belongs to the WzzB/Cld/Rol family. (353 aa)
wecAUndecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55). (362 aa)
emrB-2Multidrug resistance protein B; Multidrug MFS transporte; with EmrA is involved in resistance to hydrophobic antibiotics such as nalidixic acid; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the major facilitator superfamily. (506 aa)
secYPreprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (443 aa)
ftsNCell division protein FtsN; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases. (262 aa)
menA1,4-dihydroxy-2-naphthoate polyprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. (305 aa)
AOM41723.1Two-component system sensor histidine kinase CpxA; Derived by automated computational analysis using gene prediction method: Protein Homology. (458 aa)
AOM41751.13-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (425 aa)
yidCMembrane protein insertase YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. (537 aa)
atpCF0F1 ATP synthase subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane. (140 aa)
atpDF0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (460 aa)
atpGF0F1 ATP synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (287 aa)
atpAF0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (513 aa)
atpHATP synthase F1 subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (177 aa)
atpF-2F0F1 ATP synthase subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (156 aa)
atpEATP F0F1 synthase subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (81 aa)
atpBF0F1 ATP synthase subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (274 aa)
rbsARibose ABC transporter ATP-binding protein RbsA; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (506 aa)
rbsCRibose ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. (323 aa)
AOM41827.1MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the major facilitator superfamily. (460 aa)
rrf5S ribosomal RNA; Transports acetate; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (553 aa)
AOM41869.1PTS trehalose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology. (477 aa)
AOM41874.1Chloramphenicol efflux MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (421 aa)
glpGRhomboid family intramembrane serine protease GlpG; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. (278 aa)
AOM41912.1EnvZ; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa)
AOM42923.1Phosphate ABC transporter permease subunit PstC; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (318 aa)
AOM41914.1Phosphate ABC transporter, permease protein PstA; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
pstBPhosphate ABC transporter ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (258 aa)
AOM41918.1Amino acid ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa)
AOM41919.1ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (247 aa)
gltSSodium/glutamate symporter; Catalyzes the sodium-dependent transport of glutamate. Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family. (403 aa)
AOM41957.1Peptide transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)
AOM41958.1Peptide transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa)
AOM41967.1Inner membrane protein YhjD; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
AOM42006.1Autoinducer 2 ABC transporter permease LsrC; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. (337 aa)
AOM42007.1With IsrABC is involved with autoinducer 2 import; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. (338 aa)
A9255_16555Hydrolase; Frameshifted; incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (201 aa)
AOM42029.1PTS N-acetylmuramic acid transporter subunits IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology. (488 aa)
kefGGlutathione-regulated potassium-efflux system ancillary protein KefG; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB. (187 aa)
kefBGlutathione-regulated potassium-efflux system protein KefB; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. (602 aa)
secEPreprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. (127 aa)
malKMaltose/maltodextrin transporter ATP-binding protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Maltooligosaccharide importer (TC 3.A.1.1.1) family. (369 aa)
malFWith MalKGE is involved in maltose transport into the cell; Derived by automated computational analysis using gene prediction method: Protein Homology. (518 aa)
malGMaltose transporter permease; With MalKFE is involved in the transport of maltose into the cell; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa)
AOM42082.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (416 aa)
frdDFumarate reductase; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (117 aa)
frdCFumarate reductase subunit C; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (131 aa)
AOM42937.1Hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (222 aa)
ftsYSignal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. (558 aa)
ftsECell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. (221 aa)
AOM42104.1Cell division protein FtsX; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. (324 aa)
AOM42118.1Sodium/panthothenate symporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (480 aa)
A9255_17145Rod shape-determining protein MreC; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family. (162 aa)
lptCLPS export ABC transporter periplasmic protein LptC; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. (197 aa)
AOM42941.1ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (260 aa)
AOM42171.1Aerobic respiration two-component sensor histidine kinase ArcB; Derived by automated computational analysis using gene prediction method: Protein Homology. (765 aa)
mtgAMonofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. (238 aa)
AOM42185.1Lysine transporter LysE; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa)
plsYGlycerol-3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (218 aa)
parCDNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. (748 aa)
djlAMolecular chaperone DjlA; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host. (269 aa)
thiQThiamine ABC transporter ATP-binding protein; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family. (233 aa)
thiPThiamine/thiamine pyrophosphate ABC transporter permease ThiP; Permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; Derived by automated computational analysis using gene prediction method: Protein Homology. (534 aa)
lgtProlipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (296 aa)
AOM42313.1Derived by automated computational analysis using gene prediction method: Protein Homology. (445 aa)
sydSecY-interacting protein; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family. (183 aa)
AOM42336.1RIP metalloprotease RseP; Derived by automated computational analysis using gene prediction method: Protein Homology. (450 aa)
AOM42356.1DL-methionine transporter permease subunit; Part of the MetNIQ methionine uptake system; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa)
metND-methionine ABC transporter, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (343 aa)
ubiA4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. (284 aa)
plsBGlycerol-3-phosphate 1-O-acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPAT/DAPAT family. (824 aa)
AOM42370.1Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (123 aa)
AOM42441.1Disulfide bond formation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (188 aa)
A9255_18950Peptidase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (445 aa)
AOM42456.1Na+/H+ antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (549 aa)
ubiBUbiquinone biosynthesis regulatory protein kinase UbiB; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. (545 aa)
tatAPreprotein translocase subunit TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (84 aa)
tatBTwin arginine-targeting protein translocase TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. (165 aa)
tatCTwin arginine-targeting protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. (262 aa)
ubiD3-octaprenyl-4-hydroxybenzoate decarboxylase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. (490 aa)
AOM42478.1Potassium transporter; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family. (483 aa)
ftsBCell division protein FtsB; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. (105 aa)
fbpCFerric transporter ATP-binding subunit; Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system. (346 aa)
AOM42523.1Iron ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (692 aa)
AOM42535.1ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
lpxHUDP-2,3-diacylglucosamine diphosphatase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (240 aa)
tppBPeptide ABC transporter permease; Proton-dependent permease that transports di- and tripeptides; Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpB subfamily. (484 aa)
AOM42743.1Hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (285 aa)
cobSadenosylcobinamide-GDP ribazoletransferase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (254 aa)
nuoBNADH dehydrogenase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (224 aa)
nuoANADH-quinone oxidoreductase subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family. (143 aa)
AOM39430.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (151 aa)
dedDCell division protein DedD; Non-essential cell division protein that could be required for efficient cell constriction. (219 aa)
AOM39385.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (477 aa)
AOM39375.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa)
zipACell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. (314 aa)
cysZSulfate transporter CysZ; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway; Belongs to the CysZ family. (254 aa)
cysASulfate/thiosulfate transporter subunit; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. (362 aa)
AOM39327.1Sulfate/thiosulfate transporter subunit; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (276 aa)
AOM39315.1Cytoskeletal protein RodZ; Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis. Belongs to the RodZ family. (339 aa)
AOM39308.1Hypothetical protein; Protects the bacterial cell from host peptidases. (1690 aa)
eraGTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (301 aa)
lepAElongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (598 aa)
aqpZAquaporin Z; Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity; Belongs to the MIP/aquaporin (TC 1.A.8) family. (235 aa)
dctAC4-dicarboxylate transporter DctA; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane. Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (439 aa)
mdtHMultidrug resistance protein MdtH; Confers resistance to norfloxacin and enoxacin; Derived by automated computational analysis using gene prediction method: Protein Homology. (401 aa)
murJMurein biosynthesis integral membrane protein MurJ; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (512 aa)
znuCZinc ABC transporter ATP-binding protein ZnuC; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family. (252 aa)
lpxMLipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A. (322 aa)
AOM39893.1Spermidine export protein MdtJ; Catalyzes the excretion of spermidine. (130 aa)
AOM39894.1Multidrug transporter; Catalyzes the excretion of spermidine. (110 aa)
AOM39960.1NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. (462 aa)
AOM39980.1Lysine transporter LysE; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa)
rnfAElectron transport complex subunit RsxA; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. (193 aa)
rnfBElectron transport complex subunit RsxB; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily. (213 aa)
rnfCElectron transport complex subunit RsxC; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. (628 aa)
rnfDElectron transport complex subunit RsxD; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family. (359 aa)
rnfGElectron transport complex subunit RsxG; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family. (210 aa)
rnfEElectron transport complex subunit RsxE; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. (228 aa)
lapBLipopolysaccharide assembly protein LapB; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family. (389 aa)
lapAHypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. (104 aa)
AOM40121.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)
AOM40123.1Septation protein A; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family. (178 aa)
AOM40130.1TonB system transport protein TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. (233 aa)
clsACardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. (486 aa)
AOM40134.1Peptide ABC transporter permease; With OppABDF is involved in the transport of oligopeptides of up to 5 amino acids into the cell; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
oppBOligopeptide transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa)
AOM40224.1SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane; Derived by automated computational analysis using gene prediction method: Protein Homology. (630 aa)
nhaBNa+/H+ antiporter NhaB; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family. (514 aa)
dsbBDisulfide bond formation protein B; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. (172 aa)
AOM40276.1TIGR01620 family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (356 aa)
AOM40283.1Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (321 aa)
AOM40284.1Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa)
AOM40301.1Bcr/CflA family multidrug efflux transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (403 aa)
mdtKMATE family efflux transporter; Multidrug efflux pump that functions probably as a Na(+)/drug antiporter; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily. (457 aa)
AOM40317.1Iron ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (338 aa)
hmuVHeme ABC transporter ATP-binding protein; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system. (264 aa)
arnF4-amino-4-deoxy-L-arabinose-phospho-UDP flippase; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnF family. (128 aa)
arnE4-amino-4-deoxy-L-arabinose-phospho-UDP flippase; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnE family. (115 aa)
arnT4-amino-4-deoxy-L-arabinose lipid A transferase; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. Belongs to the glycosyltransferase 83 family. (553 aa)
arnCUndecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase; Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. (325 aa)
btuDVitamin B12 ABC transporter ATP-binding protein BtuD; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. (255 aa)
btuCVitamin B12 ABC transporter permease BtuC; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane. (331 aa)
htpXZinc metalloprotease HtpX; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase M48B family. (294 aa)
AOM40367.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (152 aa)
mntPHypothetical protein; Probably functions as a manganese efflux pump. Belongs to the MntP (TC 9.B.29) family. (206 aa)
AOM40391.1Bcr/CflA family drug resistance efflux transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (402 aa)
hflDHflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; Derived by automated computational analysis using gene prediction method: Protein Homology. (208 aa)
AOM42833.1Sensor protein PhoQ; Derived by automated computational analysis using gene prediction method: Protein Homology. (507 aa)
AOM40451.1Lipoprotein transporter subunit LolE; Derived by automated computational analysis using gene prediction method: Protein Homology. (415 aa)
lolDLipoprotein releasing system, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. (239 aa)
AOM40453.1Outer membrane-specific lipoprotein transporter subunit LolC; Part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
mltGCell division protein YceG; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (341 aa)
rneRibonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. (1077 aa)
dldD-lactate dehydrogenase; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. (584 aa)
AOM40550.1Iron-siderophore ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (361 aa)
AOM40554.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0324 family. (360 aa)
AOM40558.1Tryptophan transporter of high affinity; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa)
lpxTHypothetical protein; Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1- diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P); Belongs to the LpxT phosphotransferase family. (234 aa)
AOM40565.1Bcr/CflA family drug resistance efflux transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
rcsCTwo-component system sensor histidine kinase/response regulator; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. (939 aa)
rcsDPhosphotransferase RcsD; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB. (907 aa)
AOM40605.1Tyrosine transporter TyrP; Tyrosine specific permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (401 aa)
pyrDDihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (336 aa)
msbALipid ABC transporter permease/ATP-binding protein; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. (582 aa)
AOM40694.1Cell division protein FtsK; Derived by automated computational analysis using gene prediction method: Protein Homology. (1197 aa)
macBMacrolide ABC transporter permease/ATP-binding protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. (646 aa)
AOM40710.1Arginine transporter permease subunit ArtQ; With ArtPMJI transports arginine across the inner membrane; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
artMArginine transporter permease subunit ArtM; With ArtPQJI acts to transport arginine across the inner membrane; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa)
AOM40738.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (161 aa)
modCMolybdenum ABC transporter ATP-binding protein; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family. (354 aa)
modBMolybdate ABC transporter permease; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (230 aa)
tolRProtein TolR; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction. (143 aa)
tolQProtein TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction. (229 aa)
AOM40815.1Cytochrome d terminal oxidase subunit 1; Part of the aerobic respiratory chain; catalyzes the ubiquinol to ubiquinone; Derived by automated computational analysis using gene prediction method: Protein Homology. (523 aa)
sdhASuccinate dehydrogenase flavoprotein subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (588 aa)
sdhDSuccinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (115 aa)
kdpAPotassium-transporting ATPase subunit KdpA; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. (565 aa)
kdpBK+-transporting ATPase subunit B; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. (688 aa)
kdpCK+-transporting ATPase subunit C; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex. (193 aa)
AOM40847.1Derived by automated computational analysis using gene prediction method: Protein Homology. (453 aa)
AOM40864.1PTS N-acetyl-D-glucosamine transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (504 aa)
lntApolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. (509 aa)
AOM40873.1Amino acid ABC transporter permease; With GltIKL is involved in the transport of glutamate and aspartate; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)
AOM40874.1Amino acid ABC transporter permease; With GltJLPS and GadC for glutamate and GltJLP, DctA and DcuAB for aspartate is involved in the transport of glutamate and aspartate; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
mrdAPenicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. (636 aa)
mrdBRod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (370 aa)
AOM40886.1Potassium transporter TrkG; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family. (486 aa)
crcBFluoride ion transporter CrcB; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. (124 aa)
emrBMultidrug resistance protein B; Multidrug MFS transporte; with EmrA is involved in resistance to hydrophobic antibiotics such as nalidixic acid; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the major facilitator superfamily. (513 aa)
AOM40899.1Iron ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (347 aa)
AOM40900.1Iron ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (335 aa)
aasBifunctional 2-acylglycerophosphoethanolamine acyltransferase/acyl-ACP synthetase; Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family. (715 aa)
gptXanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. (151 aa)
AOM40940.1High-affinity choline transporter BetT; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the BCCT transporter (TC 2.A.15) family. (680 aa)
AOM40948.1FAD:protein FMN transferase ApbE; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family. (342 aa)
nqrFNADH:ubiquinone reductase (Na(+)-transporting) subunit F; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway. (408 aa)
nqrENADH:ubiquinone reductase (Na(+)-transporting) subunit E; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family. (198 aa)
nqrDNADH:ubiquinone reductase (Na(+)-transporting) subunit D; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family. (209 aa)
nqrCNa(+)-translocating NADH-quinone reductase subunit C; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. (264 aa)
nqrBNADH:ubiquinone reductase (Na(+)-transporting) subunit B; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. (412 aa)
AOM42865.1Multidrug transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (398 aa)
argOArginine transporter; Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine; Belongs to the LysE/ArgO transporter (TC 2.A.75) family. (207 aa)
secAPreprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (902 aa)
ftsACell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. (418 aa)
ftsQCell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. (272 aa)
murGUndecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (361 aa)
ftsWCell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. (394 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (360 aa)
ftsIPeptidoglycan glycosyltransferase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. (584 aa)
ftsLCell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. (105 aa)
AOM41132.1Multidrug efflux RND transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (1049 aa)
AOM41154.1Cytochrome o ubiquinol oxidase subunit II; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
cyoEProtoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (294 aa)
A9255_11640Pyroglutamyl-peptidase I; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). (163 aa)
secFProtein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (322 aa)
secDProtein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (604 aa)
yajC_2Preprotein translocase subunit YajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. (110 aa)
AOM41230.1PTS beta-glucoside transporter subunit IIABC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (458 aa)
nhaANa(+)/H(+) antiporter NhaA; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family. (389 aa)
lspASignal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. (168 aa)
AOM41286.1Multidrug transporter; Member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations; Derived by automated computational analysis using gene prediction method: Protein Homology. (104 aa)
AOM41294.1C4-dicarboxylate transporter; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. (433 aa)
dsbDProtein-disulfide reductase DsbD; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. (596 aa)
AOM42883.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (164 aa)
AOM41408.1Alginate O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the membrane-bound acyltransferase family. (473 aa)
AOM41416.1PTS cellobiose transporter subunit IIC; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. (432 aa)
AOM41458.1Spermidine/putrescine ABC transporter permease PotC; Derived by automated computational analysis using gene prediction method: Protein Homology. (259 aa)
AOM39741.1Cytochrome D ubiquinol oxidase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology. (449 aa)
AOM39734.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (96 aa)
A9255_03510Hypothetical protein; Internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (172 aa)
AOM39715.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (150 aa)
AOM39624.1Magnesium transporter; Acts as a magnesium transporter. (487 aa)
mdtBMultidrug transporter subunit MdtB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily. (1056 aa)
mdtCMultidrug transporter subunit MdtC; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily. (1031 aa)
AOM39611.1Sodium:alanine symporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (484 aa)
pgsACDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (182 aa)
AOM39543.1Sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (494 aa)
AOM39531.1Flagellar motor switch protein FliG; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. (330 aa)
fliJFlagellar biosynthesis chaperone FliJ; Flagellar protein that affects chemotactic events. Belongs to the FliJ family. (148 aa)
fliLFlagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family. (158 aa)
AOM39525.1Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. (335 aa)
AOM39524.1Flagellar motor switch protein FliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family. (135 aa)
AOM39523.1Flagellar biosynthetic protein FliO; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)
fliPFlagellar biosynthetic protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family. (255 aa)
fliQFlagellar export apparatus protein FliQ; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family. (89 aa)
AOM39521.1Flagellar biosynthetic protein FliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family. (263 aa)
flhAFlagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. (695 aa)
flhBFlagellar biosynthesis protein FlhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family. (383 aa)
AOM39489.1Sodium:alanine symporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (458 aa)
lpxLLipid A biosynthesis lauroyl acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A). (313 aa)
lldDAlpha-hydroxy-acid oxidizing enzyme; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. (380 aa)
AOM39449.1Choline transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the BCCT transporter (TC 2.A.15) family. (664 aa)
nuoNNADH:ubiquinone oxidoreductase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (485 aa)
nuoKNADH-quinone oxidoreductase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (100 aa)
AOM39443.1NADH:ubiquinone oxidoreductase subunit J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (176 aa)
nuoINADH-quinone oxidoreductase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (180 aa)
nuoHNADH-quinone oxidoreductase subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. (325 aa)
nuoCNADH-quinone oxidoreductase subunit C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. (598 aa)
AOM41459.1Spermidine/putrescine ABC transporter permease PotB; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)
potAPutrescine/spermidine ABC transporter ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. (371 aa)
AOM41480.1Cysteine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
AOM41492.1Lysine transporter LysE; Derived by automated computational analysis using gene prediction method: Protein Homology. (206 aa)
AOM41517.1Lipoprotein NlpI; May be involved in cell division. (294 aa)
AOM41525.1Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (112 aa)
hflBATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (638 aa)
cysQ3'(2'),5'-bisphosphate nucleotidase CysQ; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (247 aa)
psdPhosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (306 aa)
corAMagnesium and cobalt transport protein CorA; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family. (317 aa)
wzyEEnterobacterial common antigen polymerase; Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units; Belongs to the WzyE family. (480 aa)
Your Current Organism:
Xenorhabdus hominickii
NCBI taxonomy Id: 351679
Other names: CIP 109072, DSM 17903, X. hominickii, Xenorhabdus hominickii Taillez et al. 2006, Xenorhabdus sp. KE01, Xenorhabdus sp. KR01, Xenorhabdus sp. KR05, strain KE01
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