STRINGSTRING
cgd7_560 cgd7_560 cgd7_1140 cgd7_1140 cgd7_1590 cgd7_1590 cgd7_1720 cgd7_1720 FEN1 FEN1 cgd7_4850 cgd7_4850 cgd6_1190 cgd6_1190 cgd6_1850 cgd6_1850 cgd6_1900 cgd6_1900 cgd6_1920 cgd6_1920 cgd6_2390 cgd6_2390 cgd6_4210 cgd6_4210 cgd8_2510 cgd8_2510 cgd3_1510 cgd3_1510 cgd3_2590 cgd3_2590 cgd3_2720 cgd3_2720 cgd3_3090 cgd3_3090 cgd3_3200 cgd3_3200 cgd3_3960 cgd3_3960 cgd2_1830 cgd2_1830 cgd2_3180 cgd2_3180 cgd2_3190 cgd2_3190 cgd2_4070 cgd2_4070 cgd1_60 cgd1_60 cgd1_1420 cgd1_1420 cgd1_1490 cgd1_1490 cgd5_230 cgd5_230 cgd5_1180 cgd5_1180 cgd4_2050 cgd4_2050 cgd4_2160 cgd4_2160 cgd4_2200 cgd4_2200 cgd8_370 cgd8_370 cgd3_40 cgd3_40 cgd3_120 cgd3_120 cgd6_240 cgd6_240 cgd2_40 cgd2_40 cgd4_4470 cgd4_4470 cgd4_4320 cgd4_4320 cgd4_3920 cgd4_3920 cgd8_640 cgd8_640 cgd8_610 cgd8_610 cgd4_1490 cgd4_1490 cgd4_1450 cgd4_1450 MCM7 MCM7 cgd4_780 cgd4_780 cgd4_760 cgd4_760 cgd4_720 cgd4_720 cgd4_630 cgd4_630 cgd4_440 cgd4_440 cgd4_430 cgd4_430 cgd4_3720 cgd4_3720 cgd4_2970 cgd4_2970 cgd4_2960 cgd4_2960 cgd4_2670 cgd4_2670 cgd4_2070 cgd4_2070 cgd4_1930 cgd4_1930 cgd4_1710 cgd4_1710 cgd5_2560 cgd5_2560 cgd5_2510 cgd5_2510 cgd5_2080 cgd5_2080 cgd5_1750 cgd5_1750 cgd5_1680 cgd5_1680 cgd5_410 cgd5_410 cgd1_3700 cgd1_3700 cgd1_3540 cgd1_3540 cgd1_3420 cgd1_3420 cgd1_3410 cgd1_3410 cgd1_2740 cgd1_2740 cgd1_2640 cgd1_2640 cgd1_2530 cgd1_2530 cgd1_2410 cgd1_2410 cgd1_2320 cgd1_2320 cgd1_1840 cgd1_1840 cgd1_1220 cgd1_1220 cgd1_1180 cgd1_1180 cgd1_930 cgd1_930 cgd1_840 cgd1_840 cgd1_760 cgd1_760 cgd1_400 cgd1_400 cgd1_310 cgd1_310 cgd2_4080 cgd2_4080 cgd2_3300 cgd2_3300 cgd2_2750 cgd2_2750 cgd2_2500 cgd2_2500 cgd2_2340 cgd2_2340 cgd2_1860 cgd2_1860 cgd2_1600 cgd2_1600 cgd2_1550 cgd2_1550 cgd2_1250 cgd2_1250 cgd2_1100 cgd2_1100 cgd2_750 cgd2_750 cgd2_700 cgd2_700 cgd2_510 cgd2_510 cgd3_4290 cgd3_4290 cgd3_4060 cgd3_4060 cgd3_4050 cgd3_4050 cgd3_3860 cgd3_3860 cgd3_3820 cgd3_3820 cgd3_3470 cgd3_3470 cgd3_3400 cgd3_3400 cgd3_3170 cgd3_3170 cgd3_2960 cgd3_2960 cgd3_2520 cgd3_2520 cgd3_2210 cgd3_2210 cgd3_2020 cgd3_2020 cgd3_1470 cgd3_1470 cgd3_1450 cgd3_1450 cgd3_950 cgd3_950 cgd3_390 cgd3_390 cgd8_5410 cgd8_5410 cgd8_5320 cgd8_5320 cgd8_5190 cgd8_5190 cgd8_4950 cgd8_4950 cgd8_4920 cgd8_4920 cgd8_4070 cgd8_4070 cgd8_3970 cgd8_3970 cgd8_3950 cgd8_3950 cgd8_3360 cgd8_3360 cgd8_3300 cgd8_3300 cgd8_3210 cgd8_3210 cgd8_3180 cgd8_3180 cgd8_3010 cgd8_3010 cgd8_2940 cgd8_2940 cgd8_2670 cgd8_2670 cgd8_2380 cgd8_2380 cgd8_2150 cgd8_2150 cgd8_2020 cgd8_2020 cgd8_1630 cgd8_1630 cgd8_1620 cgd8_1620 cgd8_1410 cgd8_1410 cgd8_1350 cgd8_1350 cgd8_1300 cgd8_1300 cgd8_1240 cgd8_1240 cgd8_1230 cgd8_1230 cgd8_870 cgd8_870 cgd6_5240 cgd6_5240 cgd6_4420 cgd6_4420 cgd6_4410 cgd6_4410 cgd6_4140 cgd6_4140 cgd6_4030 cgd6_4030 cgd6_2930 cgd6_2930 cgd6_2610 cgd6_2610 cgd6_2320 cgd6_2320 cgd6_2300 cgd6_2300 cgd6_1710 cgd6_1710 cgd6_1580 cgd6_1580 Hus1-like Hus1-like cgd6_810 cgd6_810 cgd6_730 cgd6_730 cgd6_550 cgd6_550 cgd7_5420 cgd7_5420 cgd7_4690 cgd7_4690 cgd7_4620 cgd7_4620 cgd7_4470 cgd7_4470 cgd7_3680 cgd7_3680 cgd7_3350 cgd7_3350 cgd7_3050 cgd7_3050 cgd7_2920 cgd7_2920 cgd7_2760 cgd7_2760 cgd7_2700 cgd7_2700 cgd7_2660 cgd7_2660 cgd7_2390 cgd7_2390 cgd7_2370 cgd7_2370 cgd7_2310 cgd7_2310 cgd7_2000 cgd7_2000 cgd7_1920 cgd7_1920 cgd7_1850 cgd7_1850 cgd7_1690 cgd7_1690 cgd7_1440 cgd7_1440 cgd7_1190 cgd7_1190 cgd7_710 cgd7_710 cgd7_290 cgd7_290
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cgd7_560WD_REPEATS_REGION domain-containing protein. (664 aa)
cgd7_1140Uncharacterized protein. (765 aa)
cgd7_1590Uracil-DNA glycosylase, putative. (211 aa)
cgd7_1720Endonuclease III, putative. (189 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (490 aa)
cgd7_4850Protein kinase domain-containing protein. (286 aa)
cgd6_1190DNAJ protein-like, putative. (247 aa)
cgd6_1850Anaphase promoting complex subunit 10, putative. (132 aa)
cgd6_1900Kinesin heavy chain, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (714 aa)
cgd6_1920Putative kinesin heavy chain; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (925 aa)
cgd6_2390DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (835 aa)
cgd6_4210Kinesin-like boursin, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1184 aa)
cgd8_2510Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (86 aa)
cgd3_1510Cyclin-dependent kinase 3, putative; Belongs to the protein kinase superfamily. (331 aa)
cgd3_2590Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (543 aa)
cgd3_2720Putative topoisomerase VIA. (235 aa)
cgd3_3090Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (634 aa)
cgd3_3200Uncharacterized protein. (394 aa)
cgd3_3960Uncharacterized protein. (838 aa)
cgd2_1830Uncharacterized protein. (381 aa)
cgd2_3180Replication factor C subunit 5, putative. (345 aa)
cgd2_3190Protein kinase, putative. (358 aa)
cgd2_4070RECA_2 domain-containing protein. (304 aa)
cgd1_60Cyclin dependent kinase A, putative; Belongs to the protein kinase superfamily. (300 aa)
cgd1_1420DNA repair and meiosis protein Mre11 (Emb/CAB50793.1). (513 aa)
cgd1_1490NEK2 protein, putative. (555 aa)
cgd5_230Uncharacterized protein. (464 aa)
cgd5_1180DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (814 aa)
cgd4_2050RECA_2 domain-containing protein. (133 aa)
cgd4_2160Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (144 aa)
cgd4_2200Structural maintenance of chromosomes protein. (1236 aa)
cgd8_370DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1242 aa)
cgd3_40Casein kinase I; Belongs to the protein kinase superfamily. (493 aa)
cgd3_120Uncharacterized protein. (228 aa)
cgd6_240DNA replication licensing factor MCM6-like AAA ATpase; Belongs to the MCM family. (1055 aa)
cgd2_40Uncharacterized protein. (500 aa)
cgd4_4470Putative secreted, membrane-associated protein. (584 aa)
cgd4_4320ORC/CDC6 like AAA+ ATpase. (868 aa)
cgd4_3920DinB/family X-type DNA polymerase. (358 aa)
cgd8_640WD40 repeat protein. (1230 aa)
cgd8_610DNA replication repC1, AAA+ ATpase with a BRCT domain at the N-terminus. (874 aa)
cgd4_1490DNA primase; Belongs to the eukaryotic-type primase small subunit family. (402 aa)
cgd4_1450Uncharacterized protein. (898 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (857 aa)
cgd4_780DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1797 aa)
cgd4_760Putative ASF1 anti-silencing function 1 like protein. (246 aa)
cgd4_720Putative nucleosome assembly protein; Belongs to the nucleosome assembly protein (NAP) family. (347 aa)
cgd4_630RAD14/XpA, DNA excision repair protein. (199 aa)
cgd4_440XPG, DNA excision repair protein, flap endonuclease. (1147 aa)
cgd4_430ORC5 like AAA+ ATpase. (739 aa)
cgd4_3720Putative 2 TPR domains at N-terminus. (1317 aa)
cgd4_2970RAD1, NH2 terminal ERCC4-like helicase domain. (631 aa)
cgd4_2960ERCC4/XP-G-type excision repair nuclease. (308 aa)
cgd4_2670Serine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family. (3461 aa)
cgd4_2070Cyclin B like. (437 aa)
cgd4_1930Putative origin recognition complex protein subunit 2, orc2. (355 aa)
cgd4_1710Low complexity protein. (1466 aa)
cgd5_2560MutL family ATpase. (817 aa)
cgd5_2510Cdc2-like CDK2/CDC28 like protein kinase; Belongs to the protein kinase superfamily. (295 aa)
cgd5_2080Sister chromatid cohesion protein. (1803 aa)
cgd5_1750Conserved protein with N-terminal HORMA domain. (403 aa)
cgd5_1680Protein with an N-terminal domain shared with the TOG/ALp4p ike microtubule associated proteins. (1359 aa)
cgd5_410DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily. (347 aa)
cgd1_3700WD_REPEATS_REGION domain-containing protein. (453 aa)
cgd1_3540TPR repeat proteini. (1500 aa)
cgd1_3420Conserved possible MUS81 endonuclease. (734 aa)
cgd1_3410DNA replication complex GINS protein PSF2, putative. (90 aa)
cgd1_2740Centromere/kinetochore protein. (861 aa)
cgd1_2640RING-type domain-containing protein. (117 aa)
cgd1_2530TRAFAC type P-loop GTpase that may be related to kinesin; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1298 aa)
cgd1_2410RAD50. (1062 aa)
cgd1_2320Cyclin B, saccharomyces Clb4p like; Belongs to the cyclin family. (440 aa)
cgd1_1840Uncharacterized protein. (932 aa)
cgd1_1220S/T protein kinase. (758 aa)
cgd1_1180RAD54 like SWI/SNF2 ATpase. (877 aa)
cgd1_930U2 snrnp-specific A' protein. (299 aa)
cgd1_840Mnd1 domain-containing protein. (66 aa)
cgd1_760Dual specificity phosphatase. (792 aa)
cgd1_400Protein kinase, CMGC/MAPK group. (728 aa)
cgd1_310AP endonuclease of the TIM barrel fold, possible bacterial horizontal transfer. (364 aa)
cgd2_4080RP-A, OB fold single strand binding protein. (362 aa)
cgd2_3300RMI1_N domain-containing protein. (570 aa)
cgd2_2750Structural maintenance of chromosomes protein. (1349 aa)
cgd2_2500DNA polymerase epsilon subunit. (530 aa)
cgd2_2340R1 like alpha-glucan water dikinase. (1652 aa)
cgd2_1860TBC domain containing protein. (1246 aa)
cgd2_1600DNA helicase; Belongs to the MCM family. (862 aa)
cgd2_1550Origin recognition complex 4 orc4p like AAA+ ATpase. (495 aa)
cgd2_1250DNA replication licensing factor MCM4 like AAA+ ATpase; Belongs to the MCM family. (896 aa)
cgd2_1100DNA helicase; Belongs to the MCM family. (970 aa)
cgd2_750Bub3'bub3-like protein with WD40 repeats. (422 aa)
cgd2_700PMS1'MutL family ATpase. (971 aa)
cgd2_510Hypothetical coiled coil protein. (302 aa)
cgd3_4290DNA polymerase. (1488 aa)
cgd3_4060Histone transcription regulator (HIR1)-like WD40 repeat protein. (1317 aa)
cgd3_4050Cyclin; Belongs to the cyclin family. (344 aa)
cgd3_3860Coiled coil protein. (493 aa)
cgd3_3820DNA ligase. (825 aa)
cgd3_3470Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
cgd3_3400Uncharacterized protein. (110 aa)
cgd3_3170Replication factor RFC3 AAA+ ATpase. (383 aa)
cgd3_2960Uncharacterized protein. (2691 aa)
cgd3_2520TPR_REGION domain-containing protein. (573 aa)
cgd3_2210Replication protein A1 large subunit. (484 aa)
cgd3_2020PP2C like protein phosphatase. (648 aa)
cgd3_1470Dual specificity phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (314 aa)
cgd3_1450Replication factor C like AAA+ ATpase. (339 aa)
cgd3_950Hypothetical conserved protein. (706 aa)
cgd3_390RecQ SF II RNA helicase, DEXDc+HELICc. (762 aa)
cgd8_5410DNA-3-methyladenine glycosidase. (217 aa)
cgd8_5320Ser/Thr protein kinase. (345 aa)
cgd8_5190Large protein with central conserved domain, possible BCRT domain. (1442 aa)
cgd8_4950RecQ4 SF II RNA helicase. (1421 aa)
cgd8_4920WD repeats containing protein. (312 aa)
cgd8_4070SANT domain containing protein. (1632 aa)
cgd8_3970NAP, nucleosome assembly protein; Belongs to the nucleosome assembly protein (NAP) family. (197 aa)
cgd8_3950MutS like ABC ATpase involved in DNA repair. (848 aa)
cgd8_3360annotation not available (593 aa)
cgd8_3300Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (610 aa)
cgd8_3210DNA helicase II / ATP-dependent DNA helicase PcrA. (917 aa)
cgd8_3180Condensin-2 complex subunit G2. (831 aa)
cgd8_3010Smc ABC ATpase. (1268 aa)
cgd8_2940Replication factor C like AAA ATpase. (335 aa)
cgd8_2670annotation not available (698 aa)
cgd8_2380CDC45 like protein, possible horizontal transfer. (706 aa)
cgd8_2150Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (262 aa)
cgd8_2020OGG1 like 8-oxoguanine DNA glycosylase involved in DNA repair. (390 aa)
cgd8_1630Uncharacterized protein. (231 aa)
cgd8_1620DNA polymerase delta2, inactive calcineurin like phosphatase subunit. (475 aa)
cgd8_1410DNA primase large subunit. (538 aa)
cgd8_1350Topoisomerase VIA/SpoII nuclease subunit, toprim domain. (360 aa)
cgd8_1300Smc like ABC ATpase involved in DNA repair. (1314 aa)
cgd8_1240DNA polymerase epsilon catalytic subunit. (2728 aa)
cgd8_1230Protein kinase. (730 aa)
cgd8_870DNA dependent DNA polymerase alpha subunit, inactive calcineurin like phosphatase subunit. (621 aa)
cgd6_5240Protein kinase. (684 aa)
cgd6_4420ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (990 aa)
cgd6_4410DNA polymerase. (1084 aa)
cgd6_4140Coiled coil protein. (696 aa)
cgd6_4030Uncharacterized protein. (1037 aa)
cgd6_2930Protein with possible stromal antigen (SA/STAG) domain. (1404 aa)
cgd6_2610ERCC1 excision repair 1 C-terminal HhH domain. (240 aa)
cgd6_2320Multi-domain chromatin protein with WD40 repeats, bromodomain and PHD domain. (1654 aa)
cgd6_2300Meiotic check point regulator and 26S proteasome regulatory complex; PC-rep repeats. (2006 aa)
cgd6_1710Mcm10p-like'Mcm10p-like. (585 aa)
cgd6_1580Xeroderma pigmentosum G N-region plus xeroderma pigmentosum G I-region plus HhH2 domain. (482 aa)
Hus1-likeHus1-like mitotic and DNA damage checkpoint protein. (336 aa)
cgd6_810Swift like BRCT domain. (419 aa)
cgd6_73014-3-3 domain containing protein. (1937 aa)
cgd6_550Pch2p like AAA ATpase; Belongs to the AAA ATPase family. (546 aa)
cgd7_5420DUF1767 domain-containing protein. (523 aa)
cgd7_4690RF-C paralog (Ctf18p) AAA+ ATpase. (914 aa)
cgd7_4620Rf-A (OB fold protein). (707 aa)
cgd7_4470CDC14 phosphatase. (453 aa)
cgd7_3680TPR repeat protein. (791 aa)
cgd7_3350Eukaryotic DNA topoisomerase I. (653 aa)
cgd7_3050Protein kinase. (651 aa)
cgd7_2920DNA replication licensing factor MCM5 like AAA+ ATpase; Belongs to the MCM family. (791 aa)
cgd7_2760Separin (Caspase fold protease). (2442 aa)
cgd7_2700SMC3'SMC type chromosomal ABC ATpase. (1304 aa)
cgd7_2660RAD24/Rf-C activator 1 AAA+ ATpase. (701 aa)
cgd7_2390Tyrosyl-DNA phodphodiesterase 1 (Tdp1). (511 aa)
cgd7_2370EB1 like microtubule binding protein. (285 aa)
cgd7_2310ORC/CDC6 like AAA ATpase. (551 aa)
cgd7_2000Bub1p related protein kinase. (850 aa)
cgd7_1920Sld5 domain-containing protein. (144 aa)
cgd7_1850SMC4'SMC4, chromosomal ATpase with giant coiled coil regions. (1366 aa)
cgd7_1690Meiotic recombination protein DMC1-like protein; Belongs to the RecA family. (342 aa)
cgd7_1440Protein with 5 TPR domains. (649 aa)
cgd7_1190Ser/Thr protein kinase. (827 aa)
cgd7_710Possible helicase. (1239 aa)
cgd7_290RAD21-N-terminal like protein. (646 aa)
Your Current Organism:
Cryptosporidium parvum
NCBI taxonomy Id: 353152
Other names: C. parvum Iowa II, Cryptosporidium parvum Iowa II, Cryptosporidium parvum strain Iowa type II
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